ES2424088T3 - Éster de diol y de ácido graso poliinsaturado como agente antiacné - Google Patents
Éster de diol y de ácido graso poliinsaturado como agente antiacné Download PDFInfo
- Publication number
- ES2424088T3 ES2424088T3 ES09797045T ES09797045T ES2424088T3 ES 2424088 T3 ES2424088 T3 ES 2424088T3 ES 09797045 T ES09797045 T ES 09797045T ES 09797045 T ES09797045 T ES 09797045T ES 2424088 T3 ES2424088 T3 ES 2424088T3
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- Prior art keywords
- acid
- compound
- polyunsaturated fatty
- formula
- fatty acid
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- 235000020777 polyunsaturated fatty acids Nutrition 0.000 title claims abstract description 47
- 150000002009 diols Chemical class 0.000 title claims description 17
- 150000002148 esters Chemical class 0.000 title description 9
- 239000000058 anti acne agent Substances 0.000 title description 2
- 229940124340 antiacne agent Drugs 0.000 title description 2
- 150000001875 compounds Chemical class 0.000 claims abstract description 34
- 125000001183 hydrocarbyl group Chemical group 0.000 claims abstract 2
- 206010000496 acne Diseases 0.000 claims description 29
- 208000002874 Acne Vulgaris Diseases 0.000 claims description 27
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 claims description 25
- 239000000203 mixture Substances 0.000 claims description 22
- -1 hexafluorophosphate Chemical compound 0.000 claims description 17
- 238000011282 treatment Methods 0.000 claims description 13
- DTOSIQBPPRVQHS-UHFFFAOYSA-N α-Linolenic acid Chemical compound CCC=CCC=CCC=CCCCCCCCC(O)=O DTOSIQBPPRVQHS-UHFFFAOYSA-N 0.000 claims description 13
- 235000021342 arachidonic acid Nutrition 0.000 claims description 12
- 229940114079 arachidonic acid Drugs 0.000 claims description 12
- 239000002537 cosmetic Substances 0.000 claims description 12
- 238000000034 method Methods 0.000 claims description 12
- 208000008742 seborrheic dermatitis Diseases 0.000 claims description 12
- 206010039793 Seborrhoeic dermatitis Diseases 0.000 claims description 11
- 238000005859 coupling reaction Methods 0.000 claims description 11
- PSHKMPUSSFXUIA-UHFFFAOYSA-N n,n-dimethylpyridin-2-amine Chemical compound CN(C)C1=CC=CC=N1 PSHKMPUSSFXUIA-UHFFFAOYSA-N 0.000 claims description 10
- OPGOLNDOMSBSCW-CLNHMMGSSA-N Fursultiamine hydrochloride Chemical compound Cl.C1CCOC1CSSC(\CCO)=C(/C)N(C=O)CC1=CN=C(C)N=C1N OPGOLNDOMSBSCW-CLNHMMGSSA-N 0.000 claims description 8
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- XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 description 1
- YXHKONLOYHBTNS-UHFFFAOYSA-N Diazomethane Chemical compound C=[N+]=[N-] YXHKONLOYHBTNS-UHFFFAOYSA-N 0.000 description 1
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- 150000001721 carbon Chemical group 0.000 description 1
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- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 229960000541 cetyl alcohol Drugs 0.000 description 1
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- WQHOLQQHMGXEAC-UHFFFAOYSA-N dimethyl(pyridin-2-yl)azanium;chloride Chemical compound Cl.CN(C)C1=CC=CC=N1 WQHOLQQHMGXEAC-UHFFFAOYSA-N 0.000 description 1
- JVSWJIKNEAIKJW-UHFFFAOYSA-N dimethyl-hexane Natural products CCCCCC(C)C JVSWJIKNEAIKJW-UHFFFAOYSA-N 0.000 description 1
- 230000005750 disease progression Effects 0.000 description 1
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- 150000002334 glycols Chemical class 0.000 description 1
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- OEIJHBUUFURJLI-UHFFFAOYSA-N octane-1,8-diol Chemical compound OCCCCCCCCO OEIJHBUUFURJLI-UHFFFAOYSA-N 0.000 description 1
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- 210000002966 serum Anatomy 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
- C07C69/587—Monocarboxylic acid esters having at least two carbon-to-carbon double bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8105—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
- A61K8/8111—Homopolymers or copolymers of aliphatic olefines, e.g. polyethylene, polyisobutene; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Birds (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0858967 | 2008-12-22 | ||
| FR0858967A FR2940281B1 (fr) | 2008-12-22 | 2008-12-22 | Ester de diol et d'acide gras polyinsature comme agent anti-acne |
| PCT/EP2009/067701 WO2010072738A1 (fr) | 2008-12-22 | 2009-12-21 | Ester de diol et d'acide gras polyinsature comme agent anti-acne |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2424088T3 true ES2424088T3 (es) | 2013-09-27 |
Family
ID=40875013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09797045T Active ES2424088T3 (es) | 2008-12-22 | 2009-12-21 | Éster de diol y de ácido graso poliinsaturado como agente antiacné |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US8623916B2 (enExample) |
| EP (1) | EP2379484B1 (enExample) |
| JP (1) | JP5587333B2 (enExample) |
| KR (1) | KR101676055B1 (enExample) |
| CN (1) | CN102256930B (enExample) |
| AU (1) | AU2009331526B2 (enExample) |
| BR (1) | BRPI0923494B1 (enExample) |
| CA (1) | CA2747681C (enExample) |
| CL (1) | CL2011001539A1 (enExample) |
| CO (1) | CO6390033A2 (enExample) |
| ES (1) | ES2424088T3 (enExample) |
| FR (1) | FR2940281B1 (enExample) |
| GE (1) | GEP20135820B (enExample) |
| IL (1) | IL213646A (enExample) |
| MA (1) | MA32810B1 (enExample) |
| MX (1) | MX2011006659A (enExample) |
| MY (1) | MY151002A (enExample) |
| NZ (1) | NZ593781A (enExample) |
| PL (1) | PL2379484T3 (enExample) |
| PT (1) | PT2379484E (enExample) |
| RU (1) | RU2524779C2 (enExample) |
| SG (1) | SG172342A1 (enExample) |
| TN (1) | TN2011000237A1 (enExample) |
| UA (1) | UA103645C2 (enExample) |
| WO (1) | WO2010072738A1 (enExample) |
| ZA (1) | ZA201103509B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6336902B2 (ja) * | 2011-06-22 | 2018-06-06 | ビョーメ バイオサイエンシズ ピーブイティー．リミテッド | コンジュゲートベースの抗真菌性および抗菌性プロドラッグ |
| FR2983858B1 (fr) * | 2011-12-08 | 2014-01-03 | Fabre Pierre Dermo Cosmetique | Nouveaux composes inhibiteurs de la lipogenese |
| CA2920457A1 (en) * | 2013-08-08 | 2015-02-12 | Galderm Therapeutics Ltd. | Anti-acne compositions comprising bile acid-fatty acid conjugates |
| FR3033135B1 (fr) * | 2015-02-27 | 2018-03-16 | Pierre Fabre Dermo-Cosmetique | Association d'un retinoide et d'un ester de diol et d'acide gras polyinsature |
| FR3053253B1 (fr) * | 2016-07-01 | 2020-01-17 | Pierre Fabre Dermo-Cosmetique | Nouvel extrait d'akenes de silybum marianum et ses utilisations en dermatologie et dermo-cosmetique |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JPS5534762B2 (enExample) | 1975-02-07 | 1980-09-09 | ||
| DE4240674C2 (de) | 1992-11-26 | 1999-06-24 | Schuelke & Mayr Gmbh | Desodorierende Wirkstoffe |
| AU683027B2 (en) * | 1993-01-27 | 1997-10-30 | Scotia Holdings Plc | Triglycerides |
| MY118354A (en) | 1995-05-01 | 2004-10-30 | Scarista Ltd | 1,3-propane diol derivatives as bioactive compounds |
| JPH09110818A (ja) * | 1995-10-16 | 1997-04-28 | Sanshin Chem Ind Co Ltd | １−エチル−３−（３−ジメチルアミノプロピル）カルボジイミド塩酸塩の製造方法 |
| ES2176692T3 (es) | 1996-02-21 | 2002-12-01 | Stoa Sa | Composiciones cosmeticas, dermofarmaceuticas o veterinarias para el tratamiento aseptico de la piel humana o animal. |
| GB9620248D0 (en) * | 1996-09-26 | 1996-11-13 | Scotia Holdings Plc | Esters of unsaturated fatty acids |
| GB9622636D0 (en) | 1996-10-30 | 1997-01-08 | Scotia Holdings Plc | Presentation of bioactives |
| GB9710351D0 (en) * | 1997-05-20 | 1997-07-16 | Scotia Holdings Plc | Glucosamine fatty acids |
| WO2001001980A1 (en) * | 1999-07-06 | 2001-01-11 | The Regents Of The University Of California | Methods for the amelioration of neuropsychiatric disorders by inhibiting the inactivating transport of endogenous cannabinoid substances |
| GB9927629D0 (en) * | 1999-11-24 | 2000-01-19 | Croda Int Plc | Compounds |
| ES2208498T3 (es) | 2001-06-22 | 2004-06-16 | SYMRISE GMBH & CO. KG | Uso de 1,2-decanodiol contra germenes causantes de olores corporales desagradables. |
| US20070265352A1 (en) | 2002-02-19 | 2007-11-15 | Joachim Roeding | Synergistic mixtures of at least one 1,2 alkanediol such as 1,2-hexanediol and 1,2-octanediol with a further compound having antimicrobial properties |
| DE10206759A1 (de) | 2002-02-19 | 2003-08-28 | Dragoco Gerberding Co Ag | Synergistische Mischungen von 1,2-Alkandiolen |
| SE0301862D0 (sv) | 2003-06-26 | 2003-06-26 | Jan Faergeman | Sätt att inhibera tillväxten av mot antibiotika resistenta bakterier |
| DE102004031210A1 (de) * | 2004-06-28 | 2006-02-09 | Trommsdorff Gmbh & Co. Kg | MLV-Kosmetikum |
| DE10341179A1 (de) | 2003-09-06 | 2005-03-31 | Beiersdorf Ag | Wirkstoffkombination gegen Akne |
| US7935732B2 (en) | 2004-04-08 | 2011-05-03 | Isp Investments Inc. | Antimicrobial compositions |
| ES2352744T3 (es) * | 2004-04-27 | 2011-02-22 | Akzo Nobel Coatings International Bv | Pintura pigmentada que se desprende a tiras. |
| JP2006056795A (ja) * | 2004-08-18 | 2006-03-02 | Suntory Ltd | ６−ｏ−ｐｕｆａアスコルビン酸エステルを含有する皮膚化粧料並びに飲食品 |
| DE102006044849A1 (de) * | 2006-09-22 | 2008-04-03 | Symrise Gmbh & Co. Kg | Dekonjugierte Alkadiensäureester als Riech- und/oder Aromastoffe |
-
2008
- 2008-12-22 FR FR0858967A patent/FR2940281B1/fr not_active Expired - Fee Related
-
2009
- 2009-12-21 CA CA2747681A patent/CA2747681C/fr active Active
- 2009-12-21 ES ES09797045T patent/ES2424088T3/es active Active
- 2009-12-21 NZ NZ593781A patent/NZ593781A/xx not_active IP Right Cessation
- 2009-12-21 JP JP2011541506A patent/JP5587333B2/ja active Active
- 2009-12-21 CN CN200980151867.4A patent/CN102256930B/zh active Active
- 2009-12-21 UA UAA201108993A patent/UA103645C2/uk unknown
- 2009-12-21 SG SG2011046067A patent/SG172342A1/en unknown
- 2009-12-21 BR BRPI0923494A patent/BRPI0923494B1/pt not_active IP Right Cessation
- 2009-12-21 MY MYPI20112827 patent/MY151002A/en unknown
- 2009-12-21 AU AU2009331526A patent/AU2009331526B2/en not_active Ceased
- 2009-12-21 EP EP09797045.3A patent/EP2379484B1/fr active Active
- 2009-12-21 RU RU2011128264/04A patent/RU2524779C2/ru not_active IP Right Cessation
- 2009-12-21 PT PT97970453T patent/PT2379484E/pt unknown
- 2009-12-21 KR KR1020117013471A patent/KR101676055B1/ko active Active
- 2009-12-21 MX MX2011006659A patent/MX2011006659A/es active IP Right Grant
- 2009-12-21 PL PL09797045T patent/PL2379484T3/pl unknown
- 2009-12-21 GE GEAP200912313A patent/GEP20135820B/en unknown
- 2009-12-21 US US13/130,900 patent/US8623916B2/en active Active
- 2009-12-21 WO PCT/EP2009/067701 patent/WO2010072738A1/fr not_active Ceased
-
2011
- 2011-05-12 TN TN2011000237A patent/TN2011000237A1/fr unknown
- 2011-05-13 ZA ZA2011/03509A patent/ZA201103509B/en unknown
- 2011-05-20 MA MA33865A patent/MA32810B1/fr unknown
- 2011-06-15 CO CO11074814A patent/CO6390033A2/es not_active Application Discontinuation
- 2011-06-19 IL IL213646A patent/IL213646A/en active IP Right Grant
- 2011-06-21 CL CL2011001539A patent/CL2011001539A1/es unknown
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