AU2009267052B2 - Formulations of 5-fluorocytosine and uses thereof - Google Patents
Formulations of 5-fluorocytosine and uses thereof Download PDFInfo
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- AU2009267052B2 AU2009267052B2 AU2009267052A AU2009267052A AU2009267052B2 AU 2009267052 B2 AU2009267052 B2 AU 2009267052B2 AU 2009267052 A AU2009267052 A AU 2009267052A AU 2009267052 A AU2009267052 A AU 2009267052A AU 2009267052 B2 AU2009267052 B2 AU 2009267052B2
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| EP1115290B1 (en) | 1998-10-01 | 2009-03-04 | University of Southern California | Retroviral gene delivery system and methods of use |
| CA2724740C (en) | 2008-06-30 | 2017-02-21 | Tocagen Inc. | Formulations of 5-fluorocytosine and uses thereof |
| US8829173B2 (en) | 2008-09-26 | 2014-09-09 | Tocagen Inc. | Recombinant vectors |
| MX2011003039A (es) * | 2008-09-26 | 2011-08-15 | Tocagen Inc | Vectores de terapia genica y citosina deaminasas. |
| CN102459616A (zh) | 2009-06-17 | 2012-05-16 | 托卡根公司 | 复制型逆转录病毒载体的生产细胞 |
| US8865937B2 (en) * | 2009-11-06 | 2014-10-21 | Mahendra G. Dedhiya | Crystalline forms of (1S,2R)-2-(amino methyl)-N,N-diethyl-1-phenyl cyclopropane carboxamide |
| US9669049B2 (en) | 2010-10-31 | 2017-06-06 | Tocagen Inc. | Compositions comprising gamma retrovirus vectors and methods of treating proliferative disorders |
| US10130684B2 (en) * | 2011-02-03 | 2018-11-20 | Pharmedica Ltd. | Oral dissolving films for insulin administration, for treating diabetes |
| WO2013004658A1 (en) * | 2011-07-01 | 2013-01-10 | Transgene Sa | Formulations of 5-fluorocytosine and uses thereof. |
| CN102579450B (zh) * | 2012-02-10 | 2013-07-24 | 上海市嘉定区南翔医院 | 5-氟尿嘧啶在制备局限性慢性湿疹治疗药物上的应用 |
| EP2668945A1 (de) * | 2012-06-01 | 2013-12-04 | Bayer Technology Services GmbH | Genotyp- bzw. Phänotyp-basierte Arzeimittelformulierungen |
| EP2909324B1 (en) | 2012-10-25 | 2020-02-26 | Tocagen Inc. | Retroviral vector with mini-promoter cassette |
| US9642921B2 (en) | 2012-12-20 | 2017-05-09 | Tocagen Inc. | Cancer combination therapy and recombinant vectors |
| JP2018526007A (ja) | 2015-09-04 | 2018-09-13 | トカジェン インコーポレーテッド | ２ａペプチドを含む組換えベクター |
| EP3595675A4 (en) * | 2017-03-14 | 2020-12-30 | Memorial Sloan Kettering Cancer Center | MARKING, ISOLATION AND ANALYSIS OF RNA FROM RARE CELLULAR POPULATIONS |
| US20190380965A1 (en) * | 2018-06-15 | 2019-12-19 | Hemant N. Joshi | Quick Water-Dispersible Pharmaceutical Compositions of Flucytosine |
| WO2020172671A1 (en) * | 2019-02-22 | 2020-08-27 | Advantagene, Inc. | Gmci and ddri combination therapy for treating cancer |
| US11483244B2 (en) | 2020-03-18 | 2022-10-25 | Marvell Israel (M.I.S.L) Ltd. | Packet buffer spill-over in network devices |
| CN111937887B (zh) * | 2020-07-15 | 2021-09-07 | 南京师范大学 | 5-氟-2’-脱氧尿苷在抑制和/或防治螺旋藻规模化生产中褶皱臂尾轮虫的应用 |
Citations (5)
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|---|---|---|---|---|
| US6667060B1 (en) * | 1999-03-31 | 2003-12-23 | Janssen Pharmaceutica N.V. | Pregelatinized starch in a controlled release formulation |
| US6667155B2 (en) * | 2000-03-22 | 2003-12-23 | Kabushiki Kaisha Toshiba | Carrier for gene detection and its use for detecting validity of interferon therapy |
| US20050186179A1 (en) * | 2000-11-17 | 2005-08-25 | Dror Harats | Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis |
| US20060003005A1 (en) * | 2004-07-02 | 2006-01-05 | Bruce Cao | Tablet for pulsed delivery |
| US7186699B2 (en) * | 2003-06-03 | 2007-03-06 | Cell Genesys, Inc. | Method for treating cancer by vector-mediated delivery of one or more anti-angiogenic or pro-apoptotic genes |
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| CZ282747B6 (cs) | 1991-03-06 | 1997-09-17 | Emory University | Použití 1-/2-(hydroxymethyl)-1,3-oxathiazolan-5-yl/5-fluorocytosinu k výrobě léčiva pro ošetřování hepatitidy B |
| FI980901A7 (fi) | 1998-04-23 | 1999-10-24 | Orion Yhtymae Oyj | Levosimendaania säädellysti vapauttavia oraalisia koostumuksia |
| EP1115290B1 (en) | 1998-10-01 | 2009-03-04 | University of Southern California | Retroviral gene delivery system and methods of use |
| US6677155B1 (en) | 1999-04-22 | 2004-01-13 | The General Hospital Corporation | Triple hybrid amplicon vector systems to generate retroviral packaging lines |
| GB2368846B (en) | 1999-07-08 | 2004-08-25 | Univ California | Isolated Jaagsiekte retroviruses (JSRV), gene delivery vectors, and methods of use |
| CZ2003199A3 (cs) | 2000-06-23 | 2003-12-17 | Teva Pharmaceutical Industries Ltd. | Rychle expandující kompozice pro řízené uvolňování léčiva a retenci léčiva v žaludku a lékové formy obsahující tuto kompozici |
| CN1244321C (zh) * | 2003-06-26 | 2006-03-08 | 李勇 | 用于胃癌治疗的5－氟尿嘧啶胃内漂浮滞留双层缓释片 |
| US20050049207A1 (en) | 2003-09-03 | 2005-03-03 | Kaufmann Doug A. | Method of treating and preventing cancer |
| FR2874325B1 (fr) | 2004-08-19 | 2006-10-20 | Sanofi Synthelabo | Composition pharmaceutique sous forme de comprime a residence gastrique contenant de l'alfuzosine |
| WO2006127980A2 (en) | 2005-05-25 | 2006-11-30 | The Regents Of The University Of California | Optimized core promoters and uses therefor |
| WO2007069358A1 (ja) * | 2005-12-14 | 2007-06-21 | Kissei Pharmaceutical Co., Ltd. | 新規胃内滞留製剤 |
| CN101085355B (zh) * | 2007-06-20 | 2012-01-25 | 山东大学 | 5-氟胞嘧啶/类水滑石纳米杂化物及其制备方法 |
| US20090068287A1 (en) | 2007-09-12 | 2009-03-12 | Susan Welsh | Novel topical formulations of flucytosine and uses thereof |
| US9314524B2 (en) | 2007-12-31 | 2016-04-19 | Calla Therapeutics Llc | Topical formulations of Flucytosine |
| CA2724740C (en) * | 2008-06-30 | 2017-02-21 | Tocagen Inc. | Formulations of 5-fluorocytosine and uses thereof |
| MX2011003039A (es) | 2008-09-26 | 2011-08-15 | Tocagen Inc | Vectores de terapia genica y citosina deaminasas. |
| US8829173B2 (en) | 2008-09-26 | 2014-09-09 | Tocagen Inc. | Recombinant vectors |
| US8993837B2 (en) | 2010-08-13 | 2015-03-31 | Pioneer Hi-Bred International, Inc | Chimeric promoters and methods of use |
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2019
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6667060B1 (en) * | 1999-03-31 | 2003-12-23 | Janssen Pharmaceutica N.V. | Pregelatinized starch in a controlled release formulation |
| US6667155B2 (en) * | 2000-03-22 | 2003-12-23 | Kabushiki Kaisha Toshiba | Carrier for gene detection and its use for detecting validity of interferon therapy |
| US20050186179A1 (en) * | 2000-11-17 | 2005-08-25 | Dror Harats | Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis |
| US7186699B2 (en) * | 2003-06-03 | 2007-03-06 | Cell Genesys, Inc. | Method for treating cancer by vector-mediated delivery of one or more anti-angiogenic or pro-apoptotic genes |
| US20060003005A1 (en) * | 2004-07-02 | 2006-01-05 | Bruce Cao | Tablet for pulsed delivery |
Non-Patent Citations (1)
| Title |
|---|
| BONNY et al. 'Use of In Vitro Release Tests for the Prediction of the In Vivo Behavior and the Development of Flucytosine Controlled-Release Capsule,' Journal of Pharmaceutical Sciences (1995) Vol 84 No 5 pp 619-623. * |
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