AU2008358353B2 - Chloramphenicol acetyl transferase (CAT)-defective somatostatin fusion protein and uses thereof - Google Patents

Chloramphenicol acetyl transferase (CAT)-defective somatostatin fusion protein and uses thereof Download PDF

Info

Publication number
AU2008358353B2
AU2008358353B2 AU2008358353A AU2008358353A AU2008358353B2 AU 2008358353 B2 AU2008358353 B2 AU 2008358353B2 AU 2008358353 A AU2008358353 A AU 2008358353A AU 2008358353 A AU2008358353 A AU 2008358353A AU 2008358353 B2 AU2008358353 B2 AU 2008358353B2
Authority
AU
Australia
Prior art keywords
somatostatin
seq
amino acid
cat
chimeric polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2008358353A
Other languages
English (en)
Other versions
AU2008358353A1 (en
Inventor
Keith N. Haffer
James Larrick
Andrew R. Mendelsohn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Braasch Biotech LLC
Original Assignee
Braasch Biotech LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Braasch Biotech LLC filed Critical Braasch Biotech LLC
Publication of AU2008358353A1 publication Critical patent/AU2008358353A1/en
Application granted granted Critical
Publication of AU2008358353B2 publication Critical patent/AU2008358353B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/60—Feeding-stuffs specially adapted for particular animals for weanlings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12N9/1033—Chloramphenicol O-acetyltransferase (2.3.1.28)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01028—Chloramphenicol O-acetyltransferase (2.3.1.28)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Endocrinology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Husbandry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Birds (AREA)
  • Toxicology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2008358353A 2008-06-25 2008-06-25 Chloramphenicol acetyl transferase (CAT)-defective somatostatin fusion protein and uses thereof Ceased AU2008358353B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2008/068195 WO2009157926A1 (en) 2008-06-25 2008-06-25 Chloramphenicol acetyl transferase (cat)-defective somatostatin fusion protein and uses thereof

Publications (2)

Publication Number Publication Date
AU2008358353A1 AU2008358353A1 (en) 2009-12-30
AU2008358353B2 true AU2008358353B2 (en) 2013-11-07

Family

ID=41444809

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008358353A Ceased AU2008358353B2 (en) 2008-06-25 2008-06-25 Chloramphenicol acetyl transferase (CAT)-defective somatostatin fusion protein and uses thereof

Country Status (15)

Country Link
US (3) US7722881B2 (enExample)
EP (1) EP2303314B1 (enExample)
JP (1) JP5506792B2 (enExample)
KR (1) KR101555731B1 (enExample)
CN (1) CN102105163B (enExample)
AU (1) AU2008358353B2 (enExample)
CA (1) CA2728734A1 (enExample)
DK (1) DK2303314T3 (enExample)
ES (1) ES2445403T3 (enExample)
IL (1) IL209792A (enExample)
MX (1) MX2010014082A (enExample)
NZ (1) NZ590011A (enExample)
RU (1) RU2501565C2 (enExample)
WO (1) WO2009157926A1 (enExample)
ZA (1) ZA201009125B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2728735A1 (en) 2008-06-25 2009-12-30 Braasch Biotech Llc Compositions and methods for enhanced somatostatin immunogenicity
RU2501565C2 (ru) 2008-06-25 2013-12-20 Брааш Биотех Ллк Слитый белок дефектная хлорамфеникол ацетилтрансфераза (сат)-соматостатин и его применения
WO2014003538A1 (en) * 2012-06-26 2014-01-03 Biovalence Sdn. Bhd. Rapid specific pathogen free animal
JP6595340B2 (ja) 2012-11-08 2019-10-23 ペアシュイ ファルマ ソシエテ アノニム Ｃ４ｓプロテオグリカン特異的トランスポーター分子
RU2526571C1 (ru) * 2013-04-08 2014-08-27 Сергей Михайлович Юдин Инъекционный препарат для повышения спермопродукции человека и способ его применения
WO2016029013A2 (en) 2014-08-21 2016-02-25 Braasch Biotech Llc Methods for improving immunological response in vaccinated animals
WO2021024020A1 (en) 2019-08-06 2021-02-11 Astellas Pharma Inc. Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer
JP7727389B2 (ja) * 2020-02-11 2025-08-21 ブラッシュ・バイオテック・エルエルシー 乳房炎の処置及び／又は予防のための組成物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4342832A (en) 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
US4446235A (en) 1982-03-22 1984-05-01 Genentech, Inc. Method for cloning human growth hormone varient genes
WO1989004326A1 (en) * 1987-11-04 1989-05-18 California Biotechnology Inc. Alveolar surfactant proteins
US6316004B1 (en) * 1993-06-22 2001-11-13 T. Tikhonenko Chimeric somatostatin containing protein and encoding DNA, plasmids of expression, method for preparing chimeric protein, strain-producers, immunogenic composition, method for increasing the productivity of farm animals
RU2034457C1 (ru) * 1993-06-22 1995-05-10 Товарищество с ограниченной ответственностью "Ветек" Способ повышения продуктивности сельскохозяйственных животных и препарат для его осуществления
US6025368A (en) 1997-02-25 2000-02-15 Celtrix Pharmaceuticals, Inc. Method for treating the symptoms of chronic stress-related disorders using IGF
US20070048860A1 (en) 1997-10-10 2007-03-01 The Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services Carcinoembryonic antigen (CEA) peptides
PL213561B1 (pl) * 2004-01-09 2013-03-29 Inst Biotechnologii I Antybiotykow Sposób otrzymywania plazmidu, plazmid oraz zastosowania
US7998930B2 (en) 2004-11-04 2011-08-16 Hanall Biopharma Co., Ltd. Modified growth hormones
EP1896002A4 (en) 2005-06-27 2009-11-25 Biovail Lab Int Srl BUPROPIONAL SALT FORMULATIONS WITH MODIFIED RELEASE
CA2728735A1 (en) 2008-06-25 2009-12-30 Braasch Biotech Llc Compositions and methods for enhanced somatostatin immunogenicity
RU2501565C2 (ru) 2008-06-25 2013-12-20 Брааш Биотех Ллк Слитый белок дефектная хлорамфеникол ацетилтрансфераза (сат)-соматостатин и его применения

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Muderhwa J. M, et aI., Oil-in-water liposomal emulsions: characterization and potential use in vaccine delivery. J Pharm Sci. 1999 Dec; 88(12): 1332-1339. *

Also Published As

Publication number Publication date
NZ590011A (en) 2012-09-28
DK2303314T3 (da) 2014-01-13
US8367073B2 (en) 2013-02-05
US20120076806A1 (en) 2012-03-29
BRPI0822826A2 (pt) 2015-07-07
US20100136037A1 (en) 2010-06-03
JP2011525914A (ja) 2011-09-29
US7722881B2 (en) 2010-05-25
EP2303314A4 (en) 2012-07-18
MX2010014082A (es) 2011-04-07
EP2303314A1 (en) 2011-04-06
ES2445403T3 (es) 2014-03-03
WO2009157926A1 (en) 2009-12-30
CN102105163A (zh) 2011-06-22
KR20110039517A (ko) 2011-04-19
JP5506792B2 (ja) 2014-05-28
AU2008358353A1 (en) 2009-12-30
CA2728734A1 (en) 2009-12-30
US7943143B2 (en) 2011-05-17
IL209792A0 (en) 2011-02-28
KR101555731B1 (ko) 2015-09-25
EP2303314B1 (en) 2013-12-11
RU2501565C2 (ru) 2013-12-20
RU2011100104A (ru) 2012-07-20
US20090324629A1 (en) 2009-12-31
IL209792A (en) 2012-12-31
ZA201009125B (en) 2012-06-27
CN102105163B (zh) 2014-12-10

Similar Documents

Publication Publication Date Title
US8367073B2 (en) Chloramphenicol acetyl transferase (CAT)-defective somatostatin fusion protein and uses thereof
AU2009262243B2 (en) Compositions and methods for enhanced somatostatin immunogenicity
CA3145228A1 (en) African swine fever vaccine
WO2010050903A1 (en) Chimeric flagellins for vaccines
RU2034457C1 (ru) Способ повышения продуктивности сельскохозяйственных животных и препарат для его осуществления
Smooker et al. Fasciola: kinetics and quality of humoral responses to fatty acid binding protein and cathepsin l following delivery as DNA vaccines in mice
RU2677347C2 (ru) Вакцина против клещей рода rhipicephalus
US11400151B2 (en) Methods for improving immunological response in vaccinated animals
EP4382533A1 (en) Protein nanopellets for fish or teleost and crustacean vaccination
JP7727389B2 (ja) 乳房炎の処置及び／又は予防のための組成物
BRPI0822826B1 (pt) Polipeptídio quimérico com a imunogenicidade da somatostatina, composição imunogênica, composição imunológica, seus usos e métodos nãoterapêuticos para aumentar produção de leite e de carne magra
RU2614115C1 (ru) Рекомбинантный соматостатинсодержащий белок, способ его получения, инъекционный препарат для повышения мясной и молочной продуктивности сельскохозяйственных животных, а также способ использования препарата
US10052369B2 (en) Aquaporin 2 protects cattle from ticks and tick-borne parasites
AU2013217398A1 (en) Sheep nematode vaccine
US11000579B2 (en) Recombinant Eimeria maxima protein delivered as nanoparticles
EP3185896B1 (en) Exotoxin/thermolysin compositions and methods and uses for treating or preventing laminitis
CN120365382A (zh) 猪流行性腹泻病毒s蛋白及相关产品

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired