AU2008267138B9 - FSH producing cell clone - Google Patents

FSH producing cell clone Download PDF

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Publication number
AU2008267138B9
AU2008267138B9 AU2008267138A AU2008267138A AU2008267138B9 AU 2008267138 B9 AU2008267138 B9 AU 2008267138B9 AU 2008267138 A AU2008267138 A AU 2008267138A AU 2008267138 A AU2008267138 A AU 2008267138A AU 2008267138 B9 AU2008267138 B9 AU 2008267138B9
Authority
AU
Australia
Prior art keywords
nucleic acid
acid sequence
seq
recombinant
chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2008267138A
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English (en)
Other versions
AU2008267138B2 (en
AU2008267138A1 (en
Inventor
Stefan Arnold
Nanni Jelinek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Theramex HQ UK Ltd
Original Assignee
Theramex HQ UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theramex HQ UK Ltd filed Critical Theramex HQ UK Ltd
Publication of AU2008267138A1 publication Critical patent/AU2008267138A1/en
Publication of AU2008267138B2 publication Critical patent/AU2008267138B2/en
Assigned to RATIOPHARM GMBH reassignment RATIOPHARM GMBH Request to Amend Deed and Register Assignors: BIOGENERIX AG
Application granted granted Critical
Publication of AU2008267138B9 publication Critical patent/AU2008267138B9/en
Assigned to Theramex HQ UK Limited reassignment Theramex HQ UK Limited Request for Assignment Assignors: RATIOPHARM GMBH
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Reproductive Health (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AU2008267138A 2007-06-28 2008-06-27 FSH producing cell clone Active AU2008267138B9 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07111257 2007-06-28
EP07111257.7 2007-06-28
PCT/EP2008/058274 WO2009000913A1 (en) 2007-06-28 2008-06-27 Fsh producing cell clone

Publications (3)

Publication Number Publication Date
AU2008267138A1 AU2008267138A1 (en) 2008-12-31
AU2008267138B2 AU2008267138B2 (en) 2014-01-16
AU2008267138B9 true AU2008267138B9 (en) 2014-06-05

Family

ID=39745099

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008267138A Active AU2008267138B9 (en) 2007-06-28 2008-06-27 FSH producing cell clone

Country Status (23)

Country Link
US (1) US8318457B2 (enExample)
EP (2) EP2170942B1 (enExample)
JP (1) JP5570980B2 (enExample)
KR (1) KR101522217B1 (enExample)
CN (1) CN101720332B (enExample)
AU (1) AU2008267138B9 (enExample)
BR (1) BRPI0813913B1 (enExample)
CA (1) CA2690844C (enExample)
CY (1) CY1114463T1 (enExample)
DK (1) DK2170942T3 (enExample)
EA (1) EA022993B1 (enExample)
ES (1) ES2432183T3 (enExample)
HR (1) HRP20130921T1 (enExample)
IL (1) IL202280A (enExample)
MX (1) MX2010000385A (enExample)
NZ (1) NZ581702A (enExample)
PL (1) PL2170942T3 (enExample)
PT (1) PT2170942E (enExample)
RS (1) RS52976B (enExample)
SI (1) SI2170942T1 (enExample)
UA (1) UA103598C2 (enExample)
WO (1) WO2009000913A1 (enExample)
ZA (1) ZA200908168B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101573773B1 (ko) 2008-02-08 2015-12-02 바이오제너릭스 게엠베하 Ｆｓｈ의 액체 포뮬레이션
CA2755927A1 (en) * 2009-04-01 2010-10-14 Biogenerix Ag Method for purifying recombinant fsh
EP2325194A1 (en) 2009-11-24 2011-05-25 Glycotope GmbH Process for the purification of glycoproteins
JP6279466B2 (ja) * 2012-04-27 2018-02-14 Ｊｃｒファーマ株式会社 新規な発現ベクター
CN103539861B (zh) * 2013-11-01 2015-02-18 广州联康生物科技有限公司 长效重组人促卵泡激素融合蛋白
CN103554269B (zh) * 2013-11-01 2015-02-11 广州联康生物科技有限公司 重组猪促卵泡激素融合蛋白
CN103539860B (zh) * 2013-11-01 2014-12-03 广州优联康医药科技有限公司 一种长效重组人促卵泡激素融合蛋白
CN105462909B (zh) * 2015-12-31 2019-09-27 哈药集团技术中心 一种高效表达人促卵泡激素的cho细胞的培养方法
CN107460206B (zh) * 2017-09-11 2020-05-01 深圳市深研生物科技有限公司 人fsh的重组表达载体、重组细胞株及重组人fsh的制备方法
CN111349154A (zh) * 2018-12-21 2020-06-30 江苏众红生物工程创药研究院有限公司 一种重组人促卵泡激素及其制备方法和药物应用
CN110812366B (zh) * 2019-11-18 2023-11-17 珠海丽凡达生物技术有限公司 一种可用于激素补充的mRNA药物及其制备方法
CN120519466A (zh) * 2025-07-23 2025-08-22 苏州晟济药业有限公司 卵泡刺激素表达系统

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4923805A (en) 1983-11-02 1990-05-08 Integrated Genetics, Inc. Fsh
IT1206302B (it) 1987-06-26 1989-04-14 Serono Cesare Ist Ricerca Ormone follicolo-stimolante urinario
CA2018676C (en) * 1989-06-20 2003-05-06 Christie A. Kelton Novel heteropolymeric protein production methods
CA2223125A1 (en) 1995-02-17 1996-08-22 Stichting Instituut Voor Dierhouderij En Diergezondheid Production of biologically active recombinant bovine follicle stimulating hormone (recbfsh) in the baculovirus expression system
TW518235B (en) 1997-01-15 2003-01-21 Akzo Nobel Nv A gonadotropin-containing pharmaceutical composition with improved stability on prolong storage
PL346127A1 (en) 1998-07-23 2002-01-28 Lilly Co Eli Fsh and fsh variant formulations, products and methods
EP1169349B1 (en) 1999-04-16 2007-03-28 Instituto Massone S.A. Process for preparing gonadotropin compositions
WO2001058493A1 (en) * 2000-02-11 2001-08-16 Maxygen Aps Conjugates of follicle stimulating hormones
US20020127652A1 (en) 2000-02-11 2002-09-12 Schambye Hans Thalsgard Follicle stimulating hormones
KR20050083691A (ko) * 2002-09-13 2005-08-26 더 유니버시티 오브 퀸스랜드 코돈 번역 효율에 기초한 유전자 발현 시스템
KR100533794B1 (ko) * 2003-10-02 2005-12-07 주식회사 프로젠 인간 난포자극 호르몬을 대량으로 생산하는 방법
ES2333128T3 (es) 2003-12-22 2010-02-17 Ares Trading S.A. Metodo para purificar fsh.
SI1809663T1 (sl) 2004-11-09 2009-02-28 Ares Trading Sa Postopek za äśiĺ äśenje fsh
TWI369401B (en) * 2005-07-05 2012-08-01 Ares Trading Sa Serum-free culture medium for the production of recombinant gonadotropins
US20070281883A1 (en) 2006-06-05 2007-12-06 Hanna Rosenfeld Development of follicle stimulating hormone agonists and antagonists in fish

Also Published As

Publication number Publication date
PT2170942E (pt) 2013-10-22
RS52976B (sr) 2014-02-28
EP2492280A1 (en) 2012-08-29
BRPI0813913A8 (pt) 2018-02-14
CA2690844A1 (en) 2008-12-31
WO2009000913A1 (en) 2008-12-31
JP2010531148A (ja) 2010-09-24
US20120034655A1 (en) 2012-02-09
CA2690844C (en) 2016-05-17
UA103598C2 (uk) 2013-11-11
BRPI0813913A2 (pt) 2014-12-30
AU2008267138B2 (en) 2014-01-16
EP2170942A1 (en) 2010-04-07
AU2008267138A1 (en) 2008-12-31
IL202280A0 (en) 2010-06-16
CN101720332B (zh) 2014-08-13
ZA200908168B (en) 2010-07-28
BRPI0813913B1 (pt) 2022-04-19
EA022993B1 (ru) 2016-04-29
US8318457B2 (en) 2012-11-27
KR101522217B1 (ko) 2015-05-21
MX2010000385A (es) 2010-03-29
HK1140782A1 (en) 2010-10-22
DK2170942T3 (da) 2013-11-04
SI2170942T1 (sl) 2013-12-31
PL2170942T3 (pl) 2013-12-31
CN101720332A (zh) 2010-06-02
IL202280A (en) 2014-12-31
NZ581702A (en) 2011-10-28
CY1114463T1 (el) 2016-10-05
KR20100051632A (ko) 2010-05-17
EP2170942B1 (en) 2013-07-31
HRP20130921T1 (hr) 2013-11-08
EA201070071A1 (ru) 2010-10-29
JP5570980B2 (ja) 2014-08-13
ES2432183T3 (es) 2013-12-02

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FGA Letters patent sealed or granted (standard patent)
SREP Specification republished
PC Assignment registered

Owner name: THERAMEX HQ UK LIMITED

Free format text: FORMER OWNER(S): RATIOPHARM GMBH