AU2008240964B2 - Ophthalmic oil-in-water emulsions containing prostaglandins - Google Patents

Ophthalmic oil-in-water emulsions containing prostaglandins Download PDF

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Publication number
AU2008240964B2
AU2008240964B2 AU2008240964A AU2008240964A AU2008240964B2 AU 2008240964 B2 AU2008240964 B2 AU 2008240964B2 AU 2008240964 A AU2008240964 A AU 2008240964A AU 2008240964 A AU2008240964 A AU 2008240964A AU 2008240964 B2 AU2008240964 B2 AU 2008240964B2
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AU
Australia
Prior art keywords
oil
water emulsion
emulsion
prostaglandin
polyoxyethylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
AU2008240964A
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English (en)
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AU2008240964A1 (en
Inventor
Mihran Baronian
Fabio Carli
Elisabetta Chiellini
Rene Schmid
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Azad Pharma AG
Original Assignee
Azad Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Azad Pharma AG filed Critical Azad Pharma AG
Publication of AU2008240964A1 publication Critical patent/AU2008240964A1/en
Application granted granted Critical
Publication of AU2008240964B2 publication Critical patent/AU2008240964B2/en
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2008240964A 2007-04-24 2008-04-24 Ophthalmic oil-in-water emulsions containing prostaglandins Active AU2008240964B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP07008357.1 2007-04-24
EP07008357A EP1985298A1 (en) 2007-04-24 2007-04-24 Ophtalmic oil-in-water emulsions containing prostaglandins
US94269107P 2007-06-08 2007-06-08
US60/942,691 2007-06-08
PCT/EP2008/003317 WO2008128779A1 (en) 2007-04-24 2008-04-24 Ophthalmic oil-in-water emulsions containing prostaglandins

Publications (2)

Publication Number Publication Date
AU2008240964A1 AU2008240964A1 (en) 2008-10-30
AU2008240964B2 true AU2008240964B2 (en) 2013-03-07

Family

ID=38924841

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008240964A Active AU2008240964B2 (en) 2007-04-24 2008-04-24 Ophthalmic oil-in-water emulsions containing prostaglandins

Country Status (11)

Country Link
US (2) US8414904B2 (https=)
EP (2) EP1985298A1 (https=)
JP (1) JP5452472B2 (https=)
CN (1) CN101674804B (https=)
AU (1) AU2008240964B2 (https=)
CA (1) CA2683672C (https=)
ES (1) ES2425593T3 (https=)
MX (1) MX2009011391A (https=)
NZ (1) NZ579954A (https=)
RU (1) RU2460516C2 (https=)
WO (1) WO2008128779A1 (https=)

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EP1985298A1 (en) * 2007-04-24 2008-10-29 Azad Pharma AG Ophtalmic oil-in-water emulsions containing prostaglandins
JP2009040727A (ja) * 2007-08-09 2009-02-26 Towa Yakuhin Kk ラタノプロストを有効成分とする安定な点眼液剤
FR2934955B1 (fr) * 2008-08-14 2011-07-08 Commissariat Energie Atomique Encapsulation d'agents therapeutiques lipophiles ou amphiphiles dans des nanoemulsions
FR2934954B1 (fr) 2008-08-14 2011-07-22 Commissariat Energie Atomique Emulsion fluorescente de vert d'indocyanine
FR2938757B1 (fr) * 2008-11-27 2010-12-31 Octalia Technologies Vehicule sous forme d'une emulsion huile-dans-eau notamment destine a une utilisation cosmetique ou dermatologique
EP2228058A1 (en) * 2009-03-04 2010-09-15 Novagali Pharma S.A. Anionic oil-in-water emulsion containing prostaglandins and uses thereof
DE102009021372A1 (de) 2009-05-14 2010-11-18 Ursapharm Arzneimittel Gmbh Phosphatfreie pharmazeutische Zusammensetzung zur Glaukombehandlung
US9480645B2 (en) 2009-06-02 2016-11-01 Abbott Medical Optics Inc. Omega-3 oil containing ophthalmic emulsions
US20100303915A1 (en) * 2009-06-02 2010-12-02 Abbott Medical Optics Inc. Therapeutic opthalmic emulsions
AU2014250656B2 (en) * 2009-06-02 2016-05-05 Johnson & Johnson Surgical Vision, Inc. Omega-3 oil containing ophthalmic emulsions
US20100305046A1 (en) 2009-06-02 2010-12-02 Abbott Medical Optics Inc. Stable cyclosporine containing ophthalmic emulsion for treating dry eyes
PH12012500928A1 (en) * 2009-11-09 2012-11-26 Allergan Inc Compositions and methods for stimulating hair growth
EP2389939A1 (en) 2010-05-28 2011-11-30 Novagali Pharma S.A. Use of prostaglandins F2alpha and analogues for the healing of corneal and conjunctival lesions
US10272040B2 (en) 2010-08-12 2019-04-30 Nanyang Technological University Liposomal formulation for ocular drug delivery
DE102011108948A1 (de) * 2011-07-29 2013-01-31 Achim Göpferich Wässrige, kolloidale Lösungen von lipophilen Substanzen,insbesondere Arzneistofflösungen
US9278132B2 (en) * 2012-02-13 2016-03-08 Bausch & Lomb Incorporated Ophthalmic pharmaceutical compositions and methods of making and using same
EP2664329A1 (de) * 2012-05-15 2013-11-20 F. Holzer GmbH Ophthalmologisches Vehikelsystem
US9956195B2 (en) 2014-01-07 2018-05-01 Nanyang Technological University Stable liposomal formulations for ocular drug delivery
US20200237859A1 (en) 2019-01-25 2020-07-30 Newport Research, Inc. Aqueous suspensions of cyclosporin
US11324800B2 (en) 2015-01-15 2022-05-10 Wellspring Ophthalmics, Inc. Aqueous suspensions of cyclosporin
KR20170120161A (ko) * 2015-03-05 2017-10-30 알러간, 인코포레이티드 안과용 약물 전달을 위한 자가-유화 약물 전달 시스템(sedds)
KR101848124B1 (ko) * 2015-03-31 2018-04-11 단국대학교 천안캠퍼스 산학협력단 타크로리무스의 경구용 과포화성 마이크로에멀젼 조성물
CN105748415B (zh) * 2016-03-18 2019-05-07 上海方予健康医药科技有限公司 一种前列地尔冻干微乳组合物及其制备方法
KR101770324B1 (ko) 2016-11-09 2017-08-22 주식회사태준제약 안압 강하용 점안 조성물
FR3064002B1 (fr) 2017-03-14 2021-07-02 Prevor Int Melange liquide pour nettoyer les deversements de peinture, vernis, colorant et/ou lasure
EP3982930A1 (en) 2019-06-11 2022-04-20 SIFI S.p.A. Microemulsion compositions
US20210000910A1 (en) 2019-07-03 2021-01-07 Jysk Skin Solutions Pte Ltd Topical compositions
WO2021056106A1 (en) 2019-09-23 2021-04-01 Dds Research Inc. Lipid vesicle compositions with penetration enhancing agents
AU2021272476A1 (en) * 2020-05-13 2022-12-15 Follicle Pharma Ltd Compositions for delivery of bioactive agents into hair follicles
EP3919047A1 (en) * 2020-06-03 2021-12-08 AZAD Pharma AG Microemulsion for the treatment of dry eye syndrome
CN116744904A (zh) * 2020-12-24 2023-09-12 参天制药株式会社 含有依匹斯汀或其盐和硫系抗氧化剂的经皮施予用医药组合物
MX2023011157A (es) 2021-03-24 2024-01-25 Glo Pharma Inc Peptidos y metodos para reducir la pigmentacion de la piel.
ES2944784B8 (es) 2021-12-23 2026-04-21 Univ Complutense De Madrid Microemulsión oftálmica, procedimiento de obtención y uso dado a la misma
US12083204B2 (en) 2022-06-02 2024-09-10 L'oreal Topical composition for homeostatic delivery of nitric oxide and uses thereof

Citations (4)

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Publication number Priority date Publication date Assignee Title
US5849792A (en) * 1994-12-22 1998-12-15 Alcon Laboratories, Inc. Storage-stable prostaglandin compositions
US6417228B1 (en) * 1998-11-02 2002-07-09 Alcon Manufacturing, Ltd.. 13-Aza prostaglandins for the treatment of glaucoma and ocular hypertension
WO2006050836A2 (en) * 2004-11-09 2006-05-18 Novagali Pharma Sa Ophthalmic emulsions containing prostaglandins
EP1681059A1 (en) * 2003-11-07 2006-07-19 Senju Pharmaceutical Co., Ltd. Pharmaceutical composition containing prostaglandin

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Publication number Priority date Publication date Assignee Title
US5849792A (en) * 1994-12-22 1998-12-15 Alcon Laboratories, Inc. Storage-stable prostaglandin compositions
US6417228B1 (en) * 1998-11-02 2002-07-09 Alcon Manufacturing, Ltd.. 13-Aza prostaglandins for the treatment of glaucoma and ocular hypertension
EP1681059A1 (en) * 2003-11-07 2006-07-19 Senju Pharmaceutical Co., Ltd. Pharmaceutical composition containing prostaglandin
WO2006050836A2 (en) * 2004-11-09 2006-05-18 Novagali Pharma Sa Ophthalmic emulsions containing prostaglandins

Also Published As

Publication number Publication date
CA2683672A1 (en) 2008-10-30
CN101674804A (zh) 2010-03-17
EP2136782B1 (en) 2013-06-05
CN101674804B (zh) 2013-02-13
WO2008128779A1 (en) 2008-10-30
RU2460516C2 (ru) 2012-09-10
HK1133598A1 (en) 2010-04-01
US20100112016A1 (en) 2010-05-06
NZ579954A (en) 2011-04-29
ES2425593T3 (es) 2013-10-16
CA2683672C (en) 2015-10-06
EP2136782A1 (en) 2009-12-30
JP2010524992A (ja) 2010-07-22
RU2009143324A (ru) 2011-05-27
US8414904B2 (en) 2013-04-09
EP1985298A1 (en) 2008-10-29
AU2008240964A1 (en) 2008-10-30
MX2009011391A (es) 2010-02-09
US20130195936A1 (en) 2013-08-01
JP5452472B2 (ja) 2014-03-26

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