AU2008232413B2 - Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) - Google Patents
Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) Download PDFInfo
- Publication number
- AU2008232413B2 AU2008232413B2 AU2008232413A AU2008232413A AU2008232413B2 AU 2008232413 B2 AU2008232413 B2 AU 2008232413B2 AU 2008232413 A AU2008232413 A AU 2008232413A AU 2008232413 A AU2008232413 A AU 2008232413A AU 2008232413 B2 AU2008232413 B2 AU 2008232413B2
- Authority
- AU
- Australia
- Prior art keywords
- cartridge
- nitrogen dioxide
- kit
- gas
- flow
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 title claims abstract description 557
- JCXJVPUVTGWSNB-UHFFFAOYSA-N nitrogen dioxide Inorganic materials O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 title claims abstract description 67
- MGWGWNFMUOTEHG-UHFFFAOYSA-N 4-(3,5-dimethylphenyl)-1,3-thiazol-2-amine Chemical compound CC1=CC(C)=CC(C=2N=C(N)SC=2)=C1 MGWGWNFMUOTEHG-UHFFFAOYSA-N 0.000 title claims abstract description 59
- 238000006243 chemical reaction Methods 0.000 title description 27
- 239000007789 gas Substances 0.000 claims abstract description 176
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 68
- 230000001225 therapeutic effect Effects 0.000 claims abstract description 65
- 239000011149 active material Substances 0.000 claims abstract description 45
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 39
- 239000000741 silica gel Substances 0.000 claims abstract description 36
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- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 7
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- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 19
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- 206010001052 Acute respiratory distress syndrome Diseases 0.000 description 2
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- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 description 1
- IOVCWXUNBOPUCH-UHFFFAOYSA-N Nitrous acid Chemical compound ON=O IOVCWXUNBOPUCH-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B21/00—Nitrogen; Compounds thereof
- C01B21/20—Nitrogen oxides; Oxyacids of nitrogen; Salts thereof
- C01B21/24—Nitric oxide (NO)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/1005—Preparation of respiratory gases or vapours with O2 features or with parameter measurement
- A61M2016/102—Measuring a parameter of the content of the delivered gas
- A61M2016/1025—Measuring a parameter of the content of the delivered gas the O2 concentration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/02—Gases
- A61M2202/0266—Nitrogen (N)
- A61M2202/0275—Nitric oxide [NO]
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Inorganic Chemistry (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2013267074A AU2013267074B2 (en) | 2007-03-23 | 2013-12-06 | Conversion of Nitrogen Dioxide (NO2) to Nitric Oxide (NO) |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89662707P | 2007-03-23 | 2007-03-23 | |
| US60/896,627 | 2007-03-23 | ||
| US95576707P | 2007-08-14 | 2007-08-14 | |
| US60/955,767 | 2007-08-14 | ||
| PCT/US2008/003739 WO2008118360A1 (en) | 2007-03-23 | 2008-03-21 | Conversion of nitrogen dioxide (no2) to nitric oxide (no) |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2013267074A Division AU2013267074B2 (en) | 2007-03-23 | 2013-12-06 | Conversion of Nitrogen Dioxide (NO2) to Nitric Oxide (NO) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2008232413A1 AU2008232413A1 (en) | 2008-10-02 |
| AU2008232413B2 true AU2008232413B2 (en) | 2013-09-19 |
Family
ID=39788824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2008232413A Active AU2008232413B2 (en) | 2007-03-23 | 2008-03-21 | Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7947227B2 (enExample) |
| EP (1) | EP2131903B1 (enExample) |
| JP (2) | JP5575489B2 (enExample) |
| AU (1) | AU2008232413B2 (enExample) |
| CA (1) | CA2681308C (enExample) |
| WO (1) | WO2008118360A1 (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7618594B2 (en) | 2004-08-18 | 2009-11-17 | Geno Llc | Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) |
| US7560076B2 (en) * | 2004-08-18 | 2009-07-14 | Geno Llc | Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) |
| CA2681308C (en) * | 2007-03-23 | 2015-11-24 | Geno Llc | Conversion of nitrogen dioxide (no2) to nitric oxide (no) |
| WO2009097343A1 (en) * | 2008-01-28 | 2009-08-06 | Geno Llc | Conversion of nitrogen dioxide (no2) to nitric oxide (no) |
| US8434475B2 (en) * | 2008-01-31 | 2013-05-07 | Genosys, Inc. | Nitric oxide reactor and distributor apparatus and method |
| US8607785B2 (en) | 2008-08-21 | 2013-12-17 | Geno Llc | Systems and devices for generating nitric oxide |
| EP2362810A4 (en) | 2008-09-22 | 2013-09-11 | Geno Llc | CONVERSION OF NITROGEN DIOXIDE (NO2) TO NITROGEN MONOXIDE (NO) |
| CN105214193B (zh) | 2009-05-27 | 2017-11-17 | 马林克罗特医疗产品知识产权公司 | 用于药物递送调节装置的分度药物收容装置组件及分度药物递送系统 |
| JP5878866B2 (ja) | 2009-06-22 | 2016-03-08 | ゲノ エルエルシー | 一酸化窒素治療 |
| ES2873089T3 (es) * | 2010-02-01 | 2021-11-03 | Vero Biotech LLC | Sistema de administración de óxido nítrico |
| USD673654S1 (en) * | 2010-04-08 | 2013-01-01 | Bruce Santourian | Set of valve covers with coil brackets |
| AU2011245476B2 (en) * | 2010-04-26 | 2016-05-12 | VERO Biotech LLC. | Delivery of ultra pure nitric oxide (NO) |
| AU2011245474B2 (en) * | 2010-04-26 | 2016-01-07 | VERO Biotech LLC. | Nitrosyl special connector |
| WO2012038853A1 (en) | 2010-09-22 | 2012-03-29 | Koninklijke Philips Electronics N.V. | Method for generating nitric oxide |
| USD670360S1 (en) * | 2010-09-23 | 2012-11-06 | Specialty Auto Parts U.S.A., Inc. | Valve cover |
| AU2011336358B2 (en) | 2010-12-03 | 2016-09-29 | VERO Biotech LLC. | Nitric oxide treatments |
| JP2014527025A (ja) | 2011-05-27 | 2014-10-09 | ゲノ エルエルシー | 吸入用一酸化窒素を用いて血管反応性を決定する方法 |
| EP3391891A3 (en) * | 2011-06-10 | 2019-01-02 | VERO Biotech LLC | Pressurized vessel of nitric oxide (no) |
| CA2890202A1 (en) * | 2012-11-05 | 2014-05-08 | Geno Llc | Method of mixing gases including nitric oxide |
| US9795756B2 (en) | 2012-12-04 | 2017-10-24 | Mallinckrodt Hospital Products IP Limited | Cannula for minimizing dilution of dosing during nitric oxide delivery |
| KR102483889B1 (ko) * | 2012-12-04 | 2023-01-03 | 말린크로트 파마슈티칼스 아일랜드 리미티드 | 일산화질소 전달 동안 투약량의 희석을 최소화하기 위한 캐뉼라 |
| US20140318658A1 (en) * | 2013-04-26 | 2014-10-30 | Real Sensors, Inc. | Useful Life of Permeation Devices |
| US10517817B2 (en) | 2013-05-09 | 2019-12-31 | Syk Technologies, Llc | Deep topical systemic nitric oxide therapy apparatus and method |
| US10525226B2 (en) * | 2014-05-14 | 2020-01-07 | Mallinckrodt Hospital Products IP Limited | Systems and methods for indicating lifetime of an NO2-to-NO reactor cartridge used to deliver NO for inhalation therapy to a patient |
| EP4180078A1 (en) | 2014-10-20 | 2023-05-17 | VERO Biotech LLC | Nitrogen dioxide storage cassette |
| EP4400101A1 (en) | 2016-01-27 | 2024-07-17 | SYK Technologies, LLC | Nitric oxide topical application apparatus and methods |
| TWI619539B (zh) | 2016-10-14 | 2018-04-01 | 財團法人工業技術研究院 | 淨化含氮氧化物氣體的組成物及裝置 |
| BR112019016708B1 (pt) | 2017-02-27 | 2024-01-30 | Third Pole, Inc | Sistemas de geração de óxido nítrico |
| EP4095094A1 (en) | 2017-02-27 | 2022-11-30 | Third Pole, Inc. | Systems and methods for ambulatory generation of nitric oxide |
| MX2020010523A (es) | 2017-02-27 | 2021-02-09 | Third Pole Inc | Sistemas y metodos para generar oxido nitrico. |
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- 2008-03-21 CA CA2681308A patent/CA2681308C/en active Active
- 2008-03-21 AU AU2008232413A patent/AU2008232413B2/en active Active
- 2008-03-21 WO PCT/US2008/003739 patent/WO2008118360A1/en not_active Ceased
- 2008-03-21 US US12/076,723 patent/US7947227B2/en active Active
- 2008-03-21 JP JP2009554587A patent/JP5575489B2/ja not_active Expired - Fee Related
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Also Published As
| Publication number | Publication date |
|---|---|
| JP2010522130A (ja) | 2010-07-01 |
| EP2131903B1 (en) | 2018-01-24 |
| US8211368B2 (en) | 2012-07-03 |
| CA2681308C (en) | 2015-11-24 |
| US7947227B2 (en) | 2011-05-24 |
| JP2015013118A (ja) | 2015-01-22 |
| WO2008118360A1 (en) | 2008-10-02 |
| EP2131903A1 (en) | 2009-12-16 |
| JP5575489B2 (ja) | 2014-08-20 |
| US20110240020A1 (en) | 2011-10-06 |
| US20080317874A1 (en) | 2008-12-25 |
| JP5950965B2 (ja) | 2016-07-13 |
| CA2681308A1 (en) | 2008-10-02 |
| AU2008232413A1 (en) | 2008-10-02 |
| EP2131903A4 (en) | 2013-06-26 |
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