CA2681308C - Conversion of nitrogen dioxide (no2) to nitric oxide (no) - Google Patents
Conversion of nitrogen dioxide (no2) to nitric oxide (no) Download PDFInfo
- Publication number
- CA2681308C CA2681308C CA2681308A CA2681308A CA2681308C CA 2681308 C CA2681308 C CA 2681308C CA 2681308 A CA2681308 A CA 2681308A CA 2681308 A CA2681308 A CA 2681308A CA 2681308 C CA2681308 C CA 2681308C
- Authority
- CA
- Canada
- Prior art keywords
- kit
- cartridge
- nitrogen dioxide
- flow
- gas
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B21/00—Nitrogen; Compounds thereof
- C01B21/20—Nitrogen oxides; Oxyacids of nitrogen; Salts thereof
- C01B21/24—Nitric oxide (NO)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/1005—Preparation of respiratory gases or vapours with O2 features or with parameter measurement
- A61M2016/102—Measuring a parameter of the content of the delivered gas
- A61M2016/1025—Measuring a parameter of the content of the delivered gas the O2 concentration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/02—Gases
- A61M2202/0266—Nitrogen (N)
- A61M2202/0275—Nitric oxide [NO]
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Inorganic Chemistry (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89662707P | 2007-03-23 | 2007-03-23 | |
| US60/896,627 | 2007-03-23 | ||
| US95576707P | 2007-08-14 | 2007-08-14 | |
| US60/955,767 | 2007-08-14 | ||
| PCT/US2008/003739 WO2008118360A1 (en) | 2007-03-23 | 2008-03-21 | Conversion of nitrogen dioxide (no2) to nitric oxide (no) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2681308A1 CA2681308A1 (en) | 2008-10-02 |
| CA2681308C true CA2681308C (en) | 2015-11-24 |
Family
ID=39788824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2681308A Active CA2681308C (en) | 2007-03-23 | 2008-03-21 | Conversion of nitrogen dioxide (no2) to nitric oxide (no) |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7947227B2 (enExample) |
| EP (1) | EP2131903B1 (enExample) |
| JP (2) | JP5575489B2 (enExample) |
| AU (1) | AU2008232413B2 (enExample) |
| CA (1) | CA2681308C (enExample) |
| WO (1) | WO2008118360A1 (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7618594B2 (en) | 2004-08-18 | 2009-11-17 | Geno Llc | Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) |
| US7560076B2 (en) * | 2004-08-18 | 2009-07-14 | Geno Llc | Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) |
| CA2681308C (en) * | 2007-03-23 | 2015-11-24 | Geno Llc | Conversion of nitrogen dioxide (no2) to nitric oxide (no) |
| WO2009097343A1 (en) * | 2008-01-28 | 2009-08-06 | Geno Llc | Conversion of nitrogen dioxide (no2) to nitric oxide (no) |
| US8434475B2 (en) * | 2008-01-31 | 2013-05-07 | Genosys, Inc. | Nitric oxide reactor and distributor apparatus and method |
| US8607785B2 (en) | 2008-08-21 | 2013-12-17 | Geno Llc | Systems and devices for generating nitric oxide |
| EP2362810A4 (en) | 2008-09-22 | 2013-09-11 | Geno Llc | CONVERSION OF NITROGEN DIOXIDE (NO2) TO NITROGEN MONOXIDE (NO) |
| CN105214193B (zh) | 2009-05-27 | 2017-11-17 | 马林克罗特医疗产品知识产权公司 | 用于药物递送调节装置的分度药物收容装置组件及分度药物递送系统 |
| JP5878866B2 (ja) | 2009-06-22 | 2016-03-08 | ゲノ エルエルシー | 一酸化窒素治療 |
| ES2873089T3 (es) * | 2010-02-01 | 2021-11-03 | Vero Biotech LLC | Sistema de administración de óxido nítrico |
| USD673654S1 (en) * | 2010-04-08 | 2013-01-01 | Bruce Santourian | Set of valve covers with coil brackets |
| AU2011245476B2 (en) * | 2010-04-26 | 2016-05-12 | VERO Biotech LLC. | Delivery of ultra pure nitric oxide (NO) |
| AU2011245474B2 (en) * | 2010-04-26 | 2016-01-07 | VERO Biotech LLC. | Nitrosyl special connector |
| WO2012038853A1 (en) | 2010-09-22 | 2012-03-29 | Koninklijke Philips Electronics N.V. | Method for generating nitric oxide |
| USD670360S1 (en) * | 2010-09-23 | 2012-11-06 | Specialty Auto Parts U.S.A., Inc. | Valve cover |
| AU2011336358B2 (en) | 2010-12-03 | 2016-09-29 | VERO Biotech LLC. | Nitric oxide treatments |
| JP2014527025A (ja) | 2011-05-27 | 2014-10-09 | ゲノ エルエルシー | 吸入用一酸化窒素を用いて血管反応性を決定する方法 |
| EP3391891A3 (en) * | 2011-06-10 | 2019-01-02 | VERO Biotech LLC | Pressurized vessel of nitric oxide (no) |
| CA2890202A1 (en) * | 2012-11-05 | 2014-05-08 | Geno Llc | Method of mixing gases including nitric oxide |
| US9795756B2 (en) | 2012-12-04 | 2017-10-24 | Mallinckrodt Hospital Products IP Limited | Cannula for minimizing dilution of dosing during nitric oxide delivery |
| KR102483889B1 (ko) * | 2012-12-04 | 2023-01-03 | 말린크로트 파마슈티칼스 아일랜드 리미티드 | 일산화질소 전달 동안 투약량의 희석을 최소화하기 위한 캐뉼라 |
| US20140318658A1 (en) * | 2013-04-26 | 2014-10-30 | Real Sensors, Inc. | Useful Life of Permeation Devices |
| US10517817B2 (en) | 2013-05-09 | 2019-12-31 | Syk Technologies, Llc | Deep topical systemic nitric oxide therapy apparatus and method |
| US10525226B2 (en) * | 2014-05-14 | 2020-01-07 | Mallinckrodt Hospital Products IP Limited | Systems and methods for indicating lifetime of an NO2-to-NO reactor cartridge used to deliver NO for inhalation therapy to a patient |
| EP4180078A1 (en) | 2014-10-20 | 2023-05-17 | VERO Biotech LLC | Nitrogen dioxide storage cassette |
| EP4400101A1 (en) | 2016-01-27 | 2024-07-17 | SYK Technologies, LLC | Nitric oxide topical application apparatus and methods |
| TWI619539B (zh) | 2016-10-14 | 2018-04-01 | 財團法人工業技術研究院 | 淨化含氮氧化物氣體的組成物及裝置 |
| BR112019016708B1 (pt) | 2017-02-27 | 2024-01-30 | Third Pole, Inc | Sistemas de geração de óxido nítrico |
| EP4095094A1 (en) | 2017-02-27 | 2022-11-30 | Third Pole, Inc. | Systems and methods for ambulatory generation of nitric oxide |
| MX2020010523A (es) | 2017-02-27 | 2021-02-09 | Third Pole Inc | Sistemas y metodos para generar oxido nitrico. |
| CN116236665A (zh) * | 2017-06-08 | 2023-06-09 | 凯斯西储大学 | 以受控浓度输送的汽化系统 |
| US11243197B1 (en) * | 2018-07-18 | 2022-02-08 | Vero Biotech LLC | Method and apparatus for calibration of gas and liquid concentration sensors without the need for known calibration standards |
| US11672938B1 (en) | 2018-07-18 | 2023-06-13 | Vero Biotech LLC | Start-up protocols for nitric oxide delivery device |
| US11754538B1 (en) * | 2018-07-18 | 2023-09-12 | Vero Biotech Inc. | Method and apparatus for automatic calibration |
| JP7086209B2 (ja) * | 2018-10-25 | 2022-06-17 | 帝人ファーマ株式会社 | 中継投与装置及び一酸化窒素投与システム |
| WO2020232419A1 (en) | 2019-05-15 | 2020-11-19 | Third Pole, Inc. | Systems and methods for generating nitric oxide |
| CN114269685A (zh) | 2019-05-15 | 2022-04-01 | 第三极股份有限公司 | 用于一氧化氮生成的电极 |
| WO2021142472A1 (en) | 2020-01-11 | 2021-07-15 | Third Pole, Inc. | Systems and methods for nitric oxide generation with humidity control |
| EP4167920A4 (en) | 2020-06-18 | 2024-06-12 | Third Pole, Inc. | Systems and methods for preventing and treating infections with nitric oxide |
| JP2024534608A (ja) | 2021-09-23 | 2024-09-20 | サード ポール,インコーポレイテッド | 一酸化窒素を送達するシステム及び方法 |
Family Cites Families (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1021234A (en) | 1911-05-10 | 1912-03-26 | Hoechst Ag | Process of manufacturing pure nitric oxid. |
| US3930813A (en) | 1974-11-27 | 1976-01-06 | General Electric Company | Process for producing nitrogen dioxide-free oxygen-enriched gas |
| US3979501A (en) * | 1975-03-28 | 1976-09-07 | Meloy Laboratories, Inc. | Method and apparatus for converting nitrogen dioxide to nitric oxide |
| US4010897A (en) | 1976-03-31 | 1977-03-08 | Charles F. Kettering Foundation | Method and apparatus for home production and application of nitrogen fertilizer |
| IL57239A (en) | 1979-05-08 | 1982-04-30 | Alamaro Moshe | Production of nitric oxides |
| US4778450A (en) | 1979-07-12 | 1988-10-18 | Baxter Travenol Laboratories, Inc. | Fluid flow control system |
| US4270933A (en) | 1980-03-19 | 1981-06-02 | Meny Allan H | Regenerative, fluid filter |
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| GB8516333D0 (en) | 1985-06-28 | 1985-07-31 | Johnson Matthey Plc | Nitric oxide |
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| US5405919A (en) | 1992-08-24 | 1995-04-11 | The United States Of America As Represented By The Secretary Of Health And Human Services | Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions and methods of treating biological disorders |
| FR2695831B1 (fr) | 1992-09-24 | 1994-11-10 | Air Liquide | Installation et procédé de fourniture d'un mélange gazeux aux voies respiratoires d'un utilisateur. |
| WO1994016740A1 (en) | 1993-01-29 | 1994-08-04 | Brigham And Women's Hospital | The use of nitric oxide-delivering compounds for the treatment or prevention of alcoholic liver injury |
| SE501074C2 (sv) * | 1993-07-22 | 1994-11-07 | Siemens Elema Ab | Gasblandning och apparat för att tillföra gasblandningen till lungorna hos ett levande väsen |
| DE69403342T2 (de) * | 1993-09-13 | 1997-08-28 | Aga Ab | Verfahren und vorrichtung zum erzeugen von stickstoffoxyde |
| GB9320978D0 (en) | 1993-10-12 | 1993-12-01 | Higenbottam Timohy W | Nitric oxide treatment |
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| US6190704B1 (en) | 1994-09-23 | 2001-02-20 | New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery | Regulation of wound healing by nitric oxide |
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| JPH10179742A (ja) * | 1996-12-25 | 1998-07-07 | Sumitomo Seika Chem Co Ltd | 携帯用一酸化窒素−酸素ガス供給装置およびその操作方法 |
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| US20010012851A1 (en) | 1999-07-29 | 2001-08-09 | Kristin M. Lundy | Nitric oxide releasing oxindole prodrugs for anagesic, anti-inflammatory and disease-modifying use |
| FR2797398B1 (fr) * | 1999-08-11 | 2002-10-18 | Mainelab | Microparticules pour administration pulmonaire |
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| DE60042611D1 (de) | 1999-10-29 | 2009-09-03 | Nitromed Inc | Verfahren zur behandlung von gefässerkrankungen, dxid auszeichnen |
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| US7560076B2 (en) * | 2004-08-18 | 2009-07-14 | Geno Llc | Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) |
| US7618594B2 (en) * | 2004-08-18 | 2009-11-17 | Geno Llc | Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) |
| TWI348919B (en) | 2004-12-07 | 2011-09-21 | Access Business Group Int Llc | Methods for scavenging oxidizing nitrogen and oxygen species with fragrances having anti-oxidative properties |
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| JP4820596B2 (ja) * | 2005-07-21 | 2011-11-24 | 住友精化株式会社 | 一酸化窒素精製方法 |
| US20070062532A1 (en) | 2005-09-21 | 2007-03-22 | Choncholas Gary J | Apparatus and method for identifying optimal PEEP |
| JP5016032B2 (ja) * | 2006-06-07 | 2012-09-05 | トリニティ ワウンド インスティテュート, エルエルシー | 超音波を用いる酸素治療 |
| CA2681308C (en) * | 2007-03-23 | 2015-11-24 | Geno Llc | Conversion of nitrogen dioxide (no2) to nitric oxide (no) |
| WO2009097343A1 (en) * | 2008-01-28 | 2009-08-06 | Geno Llc | Conversion of nitrogen dioxide (no2) to nitric oxide (no) |
-
2008
- 2008-03-21 CA CA2681308A patent/CA2681308C/en active Active
- 2008-03-21 AU AU2008232413A patent/AU2008232413B2/en active Active
- 2008-03-21 WO PCT/US2008/003739 patent/WO2008118360A1/en not_active Ceased
- 2008-03-21 US US12/076,723 patent/US7947227B2/en active Active
- 2008-03-21 JP JP2009554587A patent/JP5575489B2/ja not_active Expired - Fee Related
- 2008-03-21 EP EP08742186.3A patent/EP2131903B1/en active Active
-
2011
- 2011-05-23 US US13/113,787 patent/US8211368B2/en active Active
-
2014
- 2014-07-02 JP JP2014136392A patent/JP5950965B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2010522130A (ja) | 2010-07-01 |
| EP2131903B1 (en) | 2018-01-24 |
| US8211368B2 (en) | 2012-07-03 |
| AU2008232413B2 (en) | 2013-09-19 |
| US7947227B2 (en) | 2011-05-24 |
| JP2015013118A (ja) | 2015-01-22 |
| WO2008118360A1 (en) | 2008-10-02 |
| EP2131903A1 (en) | 2009-12-16 |
| JP5575489B2 (ja) | 2014-08-20 |
| US20110240020A1 (en) | 2011-10-06 |
| US20080317874A1 (en) | 2008-12-25 |
| JP5950965B2 (ja) | 2016-07-13 |
| CA2681308A1 (en) | 2008-10-02 |
| AU2008232413A1 (en) | 2008-10-02 |
| EP2131903A4 (en) | 2013-06-26 |
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| Publication | Publication Date | Title |
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