CA2681308C - Conversion of nitrogen dioxide (no2) to nitric oxide (no) - Google Patents

Conversion of nitrogen dioxide (no2) to nitric oxide (no) Download PDF

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Publication number
CA2681308C
CA2681308C CA2681308A CA2681308A CA2681308C CA 2681308 C CA2681308 C CA 2681308C CA 2681308 A CA2681308 A CA 2681308A CA 2681308 A CA2681308 A CA 2681308A CA 2681308 C CA2681308 C CA 2681308C
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CA
Canada
Prior art keywords
kit
cartridge
nitrogen dioxide
flow
gas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2681308A
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English (en)
French (fr)
Other versions
CA2681308A1 (en
Inventor
David H. Fine
David P. Rounbehler
Greg Vasquez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vero Biotech Inc
Original Assignee
Geno LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geno LLC filed Critical Geno LLC
Publication of CA2681308A1 publication Critical patent/CA2681308A1/en
Application granted granted Critical
Publication of CA2681308C publication Critical patent/CA2681308C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B21/00—Nitrogen; Compounds thereof
    • C01B21/20—Nitrogen oxides; Oxyacids of nitrogen; Salts thereof
    • C01B21/24—Nitric oxide (NO)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/1005—Preparation of respiratory gases or vapours with O2 features or with parameter measurement
    • A61M2016/102—Measuring a parameter of the content of the delivered gas
    • A61M2016/1025—Measuring a parameter of the content of the delivered gas the O2 concentration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0266—Nitrogen (N)
    • A61M2202/0275—Nitric oxide [NO]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2681308A 2007-03-23 2008-03-21 Conversion of nitrogen dioxide (no2) to nitric oxide (no) Active CA2681308C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US89662707P 2007-03-23 2007-03-23
US60/896,627 2007-03-23
US95576707P 2007-08-14 2007-08-14
US60/955,767 2007-08-14
PCT/US2008/003739 WO2008118360A1 (en) 2007-03-23 2008-03-21 Conversion of nitrogen dioxide (no2) to nitric oxide (no)

Publications (2)

Publication Number Publication Date
CA2681308A1 CA2681308A1 (en) 2008-10-02
CA2681308C true CA2681308C (en) 2015-11-24

Family

ID=39788824

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2681308A Active CA2681308C (en) 2007-03-23 2008-03-21 Conversion of nitrogen dioxide (no2) to nitric oxide (no)

Country Status (6)

Country Link
US (2) US7947227B2 (enExample)
EP (1) EP2131903B1 (enExample)
JP (2) JP5575489B2 (enExample)
AU (1) AU2008232413B2 (enExample)
CA (1) CA2681308C (enExample)
WO (1) WO2008118360A1 (enExample)

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AU2009209181B2 (en) 2008-01-28 2014-01-16 VERO Biotech LLC. Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
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WO2010033916A1 (en) * 2008-09-22 2010-03-25 Geno Llc Conversion of nitrogen dioxide (no2) to nitric oxide (no)
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CA2788582C (en) * 2010-02-01 2020-01-07 VERO Biotech LLC. Nitric oxide delivery system
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CA2797674C (en) * 2010-04-26 2018-06-12 Geno Llc Nitrosyl special connector
CA2797702C (en) * 2010-04-26 2020-03-10 VERO Biotech LLC. Delivery of ultra pure nitric oxide (no)
CN103140438B (zh) * 2010-09-22 2016-06-29 皇家飞利浦电子股份有限公司 产生一氧化氮的方法
USD670360S1 (en) * 2010-09-23 2012-11-06 Specialty Auto Parts U.S.A., Inc. Valve cover
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WO2012166534A1 (en) 2011-05-27 2012-12-06 Geno Llc Method of determining vasoreactivity using inhaled nitric oxide
EP2717683A4 (en) * 2011-06-10 2015-05-06 Geno Llc PRESSURIZED CONTAINER OF NITRIC OXIDE (NO)
EP2914324A4 (en) * 2012-11-05 2016-04-20 Geno Llc METHOD FOR MIXING GASES INCLUDING STAIN OXIDE
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CA2892398C (en) 2012-12-04 2023-02-14 Ino Therapeutics Llc Cannula for minimizing dilution of dosing during nitric oxide delivery
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US10525226B2 (en) * 2014-05-14 2020-01-07 Mallinckrodt Hospital Products IP Limited Systems and methods for indicating lifetime of an NO2-to-NO reactor cartridge used to deliver NO for inhalation therapy to a patient
WO2016064928A1 (en) * 2014-10-20 2016-04-28 Geno Llc Nitrogen dioxide storage cassette
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KR102354762B1 (ko) 2017-02-27 2022-01-25 써드 폴, 아이엔씨. 산화 질소 발생 시스템 및 방법
MX2020010523A (es) 2017-02-27 2021-02-09 Third Pole Inc Sistemas y metodos para generar oxido nitrico.
US11577042B2 (en) 2017-06-08 2023-02-14 Case Western Reserve University Vaporization system for delivery in a controlled concentration
US11754538B1 (en) * 2018-07-18 2023-09-12 Vero Biotech Inc. Method and apparatus for automatic calibration
US11672938B1 (en) 2018-07-18 2023-06-13 Vero Biotech LLC Start-up protocols for nitric oxide delivery device
US11243197B1 (en) * 2018-07-18 2022-02-08 Vero Biotech LLC Method and apparatus for calibration of gas and liquid concentration sensors without the need for known calibration standards
KR102626986B1 (ko) * 2018-10-25 2024-01-19 데이진 화-마 가부시키가이샤 중계 투여 장치 및 일산화질소 투여 시스템
EP3969416A4 (en) 2019-05-15 2023-11-01 Third Pole, Inc. SYSTEMS AND DEVICES FOR GENERATING NITROGEN OXIDE
CN114269685A (zh) 2019-05-15 2022-04-01 第三极股份有限公司 用于一氧化氮生成的电极
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WO2021142472A1 (en) 2020-01-11 2021-07-15 Third Pole, Inc. Systems and methods for nitric oxide generation with humidity control
US20210395905A1 (en) 2020-06-18 2021-12-23 Third Pole, Inc. Systems and methods for preventing and treating infections with nitric oxide
US12509349B2 (en) 2020-10-16 2025-12-30 Third Pole, Inc. Nitric oxide generation process controls
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Also Published As

Publication number Publication date
CA2681308A1 (en) 2008-10-02
JP5950965B2 (ja) 2016-07-13
EP2131903A1 (en) 2009-12-16
JP2015013118A (ja) 2015-01-22
AU2008232413A1 (en) 2008-10-02
EP2131903A4 (en) 2013-06-26
US20080317874A1 (en) 2008-12-25
US8211368B2 (en) 2012-07-03
AU2008232413B2 (en) 2013-09-19
EP2131903B1 (en) 2018-01-24
US20110240020A1 (en) 2011-10-06
JP2010522130A (ja) 2010-07-01
US7947227B2 (en) 2011-05-24
WO2008118360A1 (en) 2008-10-02
JP5575489B2 (ja) 2014-08-20

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