JP5575489B2 - 二酸化窒素(no2)から酸化窒素(no)への変換 - Google Patents

二酸化窒素(no2)から酸化窒素(no)への変換 Download PDF

Info

Publication number
JP5575489B2
JP5575489B2 JP2009554587A JP2009554587A JP5575489B2 JP 5575489 B2 JP5575489 B2 JP 5575489B2 JP 2009554587 A JP2009554587 A JP 2009554587A JP 2009554587 A JP2009554587 A JP 2009554587A JP 5575489 B2 JP5575489 B2 JP 5575489B2
Authority
JP
Japan
Prior art keywords
cartridge
gas
air
kit
nitrogen dioxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2009554587A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010522130A5 (enExample
JP2010522130A (ja
Inventor
エイチ.フイネ ダビド
ピー.ロウンベフレル ダビド
バスクエズ グレグ
Original Assignee
ゲノ エルエルシー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ゲノ エルエルシー filed Critical ゲノ エルエルシー
Publication of JP2010522130A publication Critical patent/JP2010522130A/ja
Publication of JP2010522130A5 publication Critical patent/JP2010522130A5/ja
Application granted granted Critical
Publication of JP5575489B2 publication Critical patent/JP5575489B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B21/00Nitrogen; Compounds thereof
    • C01B21/20Nitrogen oxides; Oxyacids of nitrogen; Salts thereof
    • C01B21/24Nitric oxide (NO)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/1005Preparation of respiratory gases or vapours with O2 features or with parameter measurement
    • A61M2016/102Measuring a parameter of the content of the delivered gas
    • A61M2016/1025Measuring a parameter of the content of the delivered gas the O2 concentration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/02Gases
    • A61M2202/0266Nitrogen (N)
    • A61M2202/0275Nitric oxide [NO]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2009554587A 2007-03-23 2008-03-21 二酸化窒素(no2)から酸化窒素(no)への変換 Expired - Fee Related JP5575489B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US89662707P 2007-03-23 2007-03-23
US60/896,627 2007-03-23
US95576707P 2007-08-14 2007-08-14
US60/955,767 2007-08-14
PCT/US2008/003739 WO2008118360A1 (en) 2007-03-23 2008-03-21 Conversion of nitrogen dioxide (no2) to nitric oxide (no)

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014136392A Division JP5950965B2 (ja) 2007-03-23 2014-07-02 二酸化窒素(no2)から酸化窒素(no)への変換

Publications (3)

Publication Number Publication Date
JP2010522130A JP2010522130A (ja) 2010-07-01
JP2010522130A5 JP2010522130A5 (enExample) 2011-05-06
JP5575489B2 true JP5575489B2 (ja) 2014-08-20

Family

ID=39788824

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2009554587A Expired - Fee Related JP5575489B2 (ja) 2007-03-23 2008-03-21 二酸化窒素(no2)から酸化窒素(no)への変換
JP2014136392A Active JP5950965B2 (ja) 2007-03-23 2014-07-02 二酸化窒素(no2)から酸化窒素(no)への変換

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014136392A Active JP5950965B2 (ja) 2007-03-23 2014-07-02 二酸化窒素(no2)から酸化窒素(no)への変換

Country Status (6)

Country Link
US (2) US7947227B2 (enExample)
EP (1) EP2131903B1 (enExample)
JP (2) JP5575489B2 (enExample)
AU (1) AU2008232413B2 (enExample)
CA (1) CA2681308C (enExample)
WO (1) WO2008118360A1 (enExample)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7618594B2 (en) 2004-08-18 2009-11-17 Geno Llc Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
EP2724742B1 (en) * 2004-08-18 2017-11-01 Geno LLC Conversion of nitrogen dioxide (no2) to nitric oxide (no)
CA2681308C (en) * 2007-03-23 2015-11-24 Geno Llc Conversion of nitrogen dioxide (no2) to nitric oxide (no)
AU2009209181B2 (en) 2008-01-28 2014-01-16 VERO Biotech LLC. Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
US8434475B2 (en) * 2008-01-31 2013-05-07 Genosys, Inc. Nitric oxide reactor and distributor apparatus and method
US8607785B2 (en) 2008-08-21 2013-12-17 Geno Llc Systems and devices for generating nitric oxide
WO2010033916A1 (en) * 2008-09-22 2010-03-25 Geno Llc Conversion of nitrogen dioxide (no2) to nitric oxide (no)
HUE035088T2 (en) * 2009-05-27 2018-05-02 Ino Therapeutics Llc Device for engaging an indexed valve and pressurized canister assembly with a collar
CA2763804C (en) * 2009-06-22 2018-02-06 Geno Llc Nitric oxide therapies
CA2788582C (en) * 2010-02-01 2020-01-07 VERO Biotech LLC. Nitric oxide delivery system
USD673654S1 (en) * 2010-04-08 2013-01-01 Bruce Santourian Set of valve covers with coil brackets
CA2797674C (en) * 2010-04-26 2018-06-12 Geno Llc Nitrosyl special connector
CA2797702C (en) * 2010-04-26 2020-03-10 VERO Biotech LLC. Delivery of ultra pure nitric oxide (no)
CN103140438B (zh) * 2010-09-22 2016-06-29 皇家飞利浦电子股份有限公司 产生一氧化氮的方法
USD670360S1 (en) * 2010-09-23 2012-11-06 Specialty Auto Parts U.S.A., Inc. Valve cover
CA2819854A1 (en) 2010-12-03 2012-06-07 Geno Llc Nitric oxide treatments
WO2012166534A1 (en) 2011-05-27 2012-12-06 Geno Llc Method of determining vasoreactivity using inhaled nitric oxide
EP2717683A4 (en) * 2011-06-10 2015-05-06 Geno Llc PRESSURIZED CONTAINER OF NITRIC OXIDE (NO)
EP2914324A4 (en) * 2012-11-05 2016-04-20 Geno Llc METHOD FOR MIXING GASES INCLUDING STAIN OXIDE
US9795756B2 (en) 2012-12-04 2017-10-24 Mallinckrodt Hospital Products IP Limited Cannula for minimizing dilution of dosing during nitric oxide delivery
CA2892398C (en) 2012-12-04 2023-02-14 Ino Therapeutics Llc Cannula for minimizing dilution of dosing during nitric oxide delivery
US20140318658A1 (en) * 2013-04-26 2014-10-30 Real Sensors, Inc. Useful Life of Permeation Devices
US10517817B2 (en) 2013-05-09 2019-12-31 Syk Technologies, Llc Deep topical systemic nitric oxide therapy apparatus and method
US10525226B2 (en) * 2014-05-14 2020-01-07 Mallinckrodt Hospital Products IP Limited Systems and methods for indicating lifetime of an NO2-to-NO reactor cartridge used to deliver NO for inhalation therapy to a patient
WO2016064928A1 (en) * 2014-10-20 2016-04-28 Geno Llc Nitrogen dioxide storage cassette
EP4400101A1 (en) 2016-01-27 2024-07-17 SYK Technologies, LLC Nitric oxide topical application apparatus and methods
TWI619539B (zh) 2016-10-14 2018-04-01 財團法人工業技術研究院 淨化含氮氧化物氣體的組成物及裝置
RU2020113418A (ru) 2017-02-27 2020-10-05 Cёрд Поул, Инк. Системы и способы получения оксида азота в амбулаторных условиях
KR102354762B1 (ko) 2017-02-27 2022-01-25 써드 폴, 아이엔씨. 산화 질소 발생 시스템 및 방법
MX2020010523A (es) 2017-02-27 2021-02-09 Third Pole Inc Sistemas y metodos para generar oxido nitrico.
US11577042B2 (en) 2017-06-08 2023-02-14 Case Western Reserve University Vaporization system for delivery in a controlled concentration
US11754538B1 (en) * 2018-07-18 2023-09-12 Vero Biotech Inc. Method and apparatus for automatic calibration
US11672938B1 (en) 2018-07-18 2023-06-13 Vero Biotech LLC Start-up protocols for nitric oxide delivery device
US11243197B1 (en) * 2018-07-18 2022-02-08 Vero Biotech LLC Method and apparatus for calibration of gas and liquid concentration sensors without the need for known calibration standards
KR102626986B1 (ko) * 2018-10-25 2024-01-19 데이진 화-마 가부시키가이샤 중계 투여 장치 및 일산화질소 투여 시스템
EP3969416A4 (en) 2019-05-15 2023-11-01 Third Pole, Inc. SYSTEMS AND DEVICES FOR GENERATING NITROGEN OXIDE
CN114269685A (zh) 2019-05-15 2022-04-01 第三极股份有限公司 用于一氧化氮生成的电极
WO2020232414A1 (en) 2019-05-15 2020-11-19 Third Pole, Inc. Architectures for production of nitric oxide
WO2021142472A1 (en) 2020-01-11 2021-07-15 Third Pole, Inc. Systems and methods for nitric oxide generation with humidity control
US20210395905A1 (en) 2020-06-18 2021-12-23 Third Pole, Inc. Systems and methods for preventing and treating infections with nitric oxide
US12509349B2 (en) 2020-10-16 2025-12-30 Third Pole, Inc. Nitric oxide generation process controls
WO2023049873A1 (en) 2021-09-23 2023-03-30 Third Pole, Inc. Systems and methods for delivering nitric oxide
WO2023201363A2 (en) 2022-04-14 2023-10-19 Third Pole, Inc. Delivery of medicinal gas in a liquid medium

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1021234A (en) 1911-05-10 1912-03-26 Hoechst Ag Process of manufacturing pure nitric oxid.
US3930813A (en) 1974-11-27 1976-01-06 General Electric Company Process for producing nitrogen dioxide-free oxygen-enriched gas
US3979501A (en) * 1975-03-28 1976-09-07 Meloy Laboratories, Inc. Method and apparatus for converting nitrogen dioxide to nitric oxide
US4010897A (en) 1976-03-31 1977-03-08 Charles F. Kettering Foundation Method and apparatus for home production and application of nitrogen fertilizer
IL57239A (en) 1979-05-08 1982-04-30 Alamaro Moshe Production of nitric oxides
US4778450A (en) 1979-07-12 1988-10-18 Baxter Travenol Laboratories, Inc. Fluid flow control system
US4270933A (en) 1980-03-19 1981-06-02 Meny Allan H Regenerative, fluid filter
US4399942A (en) 1981-11-09 1983-08-23 Gc Industries Gas emitting device
GB8516333D0 (en) 1985-06-28 1985-07-31 Johnson Matthey Plc Nitric oxide
KR970011449B1 (ko) * 1988-01-29 1997-07-11 더 리전트 오브 디 유니버시티 오브 캘리포니아 이온전기 영동형 비침입 검체 채취 또는 이송 장치 및 방법
US4963327A (en) 1988-03-23 1990-10-16 Z-Gard, Inc. Oxygen generating module
US5683668A (en) 1990-09-20 1997-11-04 The United States Of America As Represented By The Department Of Health And Human Services Method of generating nitric oxide gas using nitric oxide complexes
US5396882A (en) 1992-03-11 1995-03-14 The General Hospital Corporation Generation of nitric oxide from air for medical uses
ATE376850T1 (de) 1990-12-05 2007-11-15 Gen Hospital Corp Vorrichtung zum behandeln einen lungengefässverengung und von asthma
US5570683A (en) 1990-12-05 1996-11-05 The General Hospital Corporation Methods and devices for treating pulmonary vasoconstriction and asthma
US5405919A (en) 1992-08-24 1995-04-11 The United States Of America As Represented By The Secretary Of Health And Human Services Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions and methods of treating biological disorders
US5525357A (en) 1992-08-24 1996-06-11 The United States Of America As Represented By The Department Of Health And Human Services Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same
FR2695831B1 (fr) 1992-09-24 1994-11-10 Air Liquide Installation et procédé de fourniture d'un mélange gazeux aux voies respiratoires d'un utilisateur.
WO1994016740A1 (en) 1993-01-29 1994-08-04 Brigham And Women's Hospital The use of nitric oxide-delivering compounds for the treatment or prevention of alcoholic liver injury
SE9302478L (sv) * 1993-07-22 1994-11-07 Siemens Elema Ab Gasblandning och apparat för att tillföra gasblandningen till lungorna hos ett levande väsen
JPH09502690A (ja) * 1993-09-13 1997-03-18 アーゲーアー アクツイエボラーグ 酸化窒素を製造する方法及び装置
GB9320978D0 (en) 1993-10-12 1993-12-01 Higenbottam Timohy W Nitric oxide treatment
US5558083A (en) 1993-11-22 1996-09-24 Ohmeda Inc. Nitric oxide delivery system
US5514204A (en) 1994-07-07 1996-05-07 The Boc Group, Inc. Process for the purification of nitric oxide
US5583101A (en) 1994-07-15 1996-12-10 Harvard College Use of nitrogen oxide species and adducts to inhibit skeletal muscle contraction
US5615669A (en) 1994-07-22 1997-04-01 Siemens Elema Ab Gas mixture and device for delivering the gas mixture to the lungs of a respiratory subject
US6190704B1 (en) 1994-09-23 2001-02-20 New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Regulation of wound healing by nitric oxide
US5823180A (en) 1995-04-03 1998-10-20 The General Hospital Corporation Methods for treating pulmonary vasoconstriction and asthma
JP3351659B2 (ja) * 1995-05-15 2002-12-03 東亜ディーケーケー株式会社 窒素酸化物用還元器
DE19517857C1 (de) 1995-05-16 1996-05-09 Ruesch Willy Ag Beatmungsbeutel
US6158432A (en) 1995-12-08 2000-12-12 Cardiopulmonary Corporation Ventilator control system and method
BR9612529A (pt) 1996-02-27 1999-08-31 Intensive Care Innovations Ltd Sistema ventilatório com administrador de gás adicional.
US5692495A (en) 1996-04-02 1997-12-02 The Boc Group, Inc. Method and apparatus for the production of nitric oxide gas mixture
SE506778C2 (sv) * 1996-08-12 1998-02-09 Siemens Elema Ab Förfarande vid blandning av gaser och en anordning för blandning av gaser
JPH10179742A (ja) * 1996-12-25 1998-07-07 Sumitomo Seika Chem Co Ltd 携帯用一酸化窒素−酸素ガス供給装置およびその操作方法
US6896899B2 (en) 1996-12-31 2005-05-24 Antioxidant Pharmaceuticals Corp. Pharmaceutical preparations of glutathione and methods of administration thereof
US5827420A (en) 1997-07-29 1998-10-27 World Precision Instruments, Inc. Method and apparatus for the generation of nitric oxide
US5994444A (en) 1997-10-16 1999-11-30 Medtronic, Inc. Polymeric material that releases nitric oxide
US6109260A (en) 1998-02-18 2000-08-29 Datex-Ohmeda, Inc. Nitric oxide administration device with timed pulse
US6103275A (en) 1998-06-10 2000-08-15 Nitric Oxide Solutions Systems and methods for topical treatment with nitric oxide
US6261594B1 (en) 1998-11-25 2001-07-17 The University Of Akron Chitosan-based nitric oxide donor compositions
US6576044B1 (en) 1999-02-25 2003-06-10 The Boc Group, Inc. Process for the purification of nitric oxide
US20010012851A1 (en) 1999-07-29 2001-08-09 Kristin M. Lundy Nitric oxide releasing oxindole prodrugs for anagesic, anti-inflammatory and disease-modifying use
FR2797398B1 (fr) * 1999-08-11 2002-10-18 Mainelab Microparticules pour administration pulmonaire
EP1194171A2 (en) 1999-09-02 2002-04-10 Rice University Nitric oxide-producing hydrogel materials
AU780261B2 (en) 1999-10-29 2005-03-10 Nitromed, Inc. Methods of treating vascular diseases characterized by nitric oxide insufficiency
US6758214B2 (en) 2000-01-28 2004-07-06 Cyterra Corporation Simple nitric oxide generator for ambulatory and/or bedside inhaled no treatment
US6270779B1 (en) * 2000-05-10 2001-08-07 United States Of America Nitric oxide-releasing metallic medical devices
DE10119083C1 (de) 2001-04-19 2002-11-28 Joachim Alfred Wuenning Kompakt-Dampf-Reformer
US6749834B2 (en) * 2001-06-19 2004-06-15 World Precision Instruments, Inc. Methods and apparatus for therapeutic treatment of respiratory, cardiac and other pathologies
EP2565157B1 (en) 2001-09-05 2017-10-04 Geno LLC Nitric oxide generation
US7531133B2 (en) * 2002-09-10 2009-05-12 Pulmonox Technologies Corporation Use of nitric oxide gas in an extracorporeal circuitry to treat blood plasma
GB2404866B (en) * 2003-08-15 2008-02-27 Shahar Hayek Respiratory apparatus
JP2007504135A (ja) 2003-08-28 2007-03-01 ニトロメッド インコーポレーティッド ニトロソ化およびニトロシル化心血管化合物、組成物、ならびに使用方法
US20050217668A1 (en) 2003-10-24 2005-10-06 Pulmonox Technologies Corporation System and elements for managing therapeutic gas administration to a spontaneously breathing non-ventilated patient
US7288664B2 (en) 2004-03-30 2007-10-30 Bela Kleiner Reverse Kleiner method for manufacturing nitrogen dioxide, nitric oxide, nitric acid, metallic ascorbates and alkyl ascorbates of vitamin C
US7618594B2 (en) 2004-08-18 2009-11-17 Geno Llc Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
EP2724742B1 (en) * 2004-08-18 2017-11-01 Geno LLC Conversion of nitrogen dioxide (no2) to nitric oxide (no)
WO2006063056A1 (en) 2004-12-07 2006-06-15 Access Business Group International Llc Methods for scavenging oxidizing nitrogen and oxygen species with fragrances having antioxidative properties
US7390346B2 (en) * 2005-05-12 2008-06-24 Praxair Technology, Inc. System and apparatus for producing primary standard gas mixtures
MX2008000817A (es) * 2005-07-18 2008-03-14 Union Engineering As Un metodo para la recuperacion de dioxido de carbon de alta pureza a partir de una fuente gaseosa que comprende compuestos de nitrogeno.
JP4820596B2 (ja) * 2005-07-21 2011-11-24 住友精化株式会社 一酸化窒素精製方法
US20070062532A1 (en) 2005-09-21 2007-03-22 Choncholas Gary J Apparatus and method for identifying optimal PEEP
JP5016032B2 (ja) * 2006-06-07 2012-09-05 トリニティ ワウンド インスティテュート, エルエルシー 超音波を用いる酸素治療
CA2681308C (en) * 2007-03-23 2015-11-24 Geno Llc Conversion of nitrogen dioxide (no2) to nitric oxide (no)
AU2009209181B2 (en) * 2008-01-28 2014-01-16 VERO Biotech LLC. Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)

Also Published As

Publication number Publication date
CA2681308A1 (en) 2008-10-02
JP5950965B2 (ja) 2016-07-13
EP2131903A1 (en) 2009-12-16
JP2015013118A (ja) 2015-01-22
CA2681308C (en) 2015-11-24
AU2008232413A1 (en) 2008-10-02
EP2131903A4 (en) 2013-06-26
US20080317874A1 (en) 2008-12-25
US8211368B2 (en) 2012-07-03
AU2008232413B2 (en) 2013-09-19
EP2131903B1 (en) 2018-01-24
US20110240020A1 (en) 2011-10-06
JP2010522130A (ja) 2010-07-01
US7947227B2 (en) 2011-05-24
WO2008118360A1 (en) 2008-10-02

Similar Documents

Publication Publication Date Title
JP5575489B2 (ja) 二酸化窒素(no2)から酸化窒素(no)への変換
JP5611955B2 (ja) 二酸化窒素(no2)の一酸化窒素(no)への変換
JP5421530B2 (ja) 二酸化窒素(no2)の酸化窒素(no)への変換
US8246725B2 (en) Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
JP6058888B2 (ja) 患者における心臓の病気の診断及び治療方法
AU2013267074B2 (en) Conversion of Nitrogen Dioxide (NO2) to Nitric Oxide (NO)
AU2015258294A1 (en) Conversion of Nitrogen Dioxide (NO2) to Nitric Oxide (NO)

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110314

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20110314

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20131001

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20131218

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20131226

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140327

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20140603

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20140702

R150 Certificate of patent or registration of utility model

Ref document number: 5575489

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

S533 Written request for registration of change of name

Free format text: JAPANESE INTERMEDIATE CODE: R313533

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

LAPS Cancellation because of no payment of annual fees