AU2008218763B2 - Prevention and treatment for osteonecrosis and osteoradionecrosis of the jaw using PDGF and a bone matrix - Google Patents

Prevention and treatment for osteonecrosis and osteoradionecrosis of the jaw using PDGF and a bone matrix Download PDF

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Publication number
AU2008218763B2
AU2008218763B2 AU2008218763A AU2008218763A AU2008218763B2 AU 2008218763 B2 AU2008218763 B2 AU 2008218763B2 AU 2008218763 A AU2008218763 A AU 2008218763A AU 2008218763 A AU2008218763 A AU 2008218763A AU 2008218763 B2 AU2008218763 B2 AU 2008218763B2
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AU
Australia
Prior art keywords
pdgf
biocompatible matrix
biocompatible
solution
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2008218763A
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English (en)
Other versions
AU2008218763A1 (en
Inventor
Jeffrey O. Hollinger
Samuel E. Lynch
Leslie A. Wisner-Lynch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomimetic Therapeutics LLC
Original Assignee
Biomimetic Therapeutics LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomimetic Therapeutics LLC filed Critical Biomimetic Therapeutics LLC
Publication of AU2008218763A1 publication Critical patent/AU2008218763A1/en
Application granted granted Critical
Publication of AU2008218763B2 publication Critical patent/AU2008218763B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
AU2008218763A 2007-02-20 2008-02-20 Prevention and treatment for osteonecrosis and osteoradionecrosis of the jaw using PDGF and a bone matrix Ceased AU2008218763B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89076307P 2007-02-20 2007-02-20
US60/890,763 2007-02-20
PCT/US2008/054354 WO2008103690A2 (en) 2007-02-20 2008-02-20 Prevention and treatment for osteonecrosis and osteoradionecrosis of the jaw using pdgf and a bone matrix

Publications (2)

Publication Number Publication Date
AU2008218763A1 AU2008218763A1 (en) 2008-08-28
AU2008218763B2 true AU2008218763B2 (en) 2013-10-24

Family

ID=39710710

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008218763A Ceased AU2008218763B2 (en) 2007-02-20 2008-02-20 Prevention and treatment for osteonecrosis and osteoradionecrosis of the jaw using PDGF and a bone matrix

Country Status (6)

Country Link
US (1) US20100151025A1 (enExample)
EP (1) EP2125000A2 (enExample)
JP (1) JP2010518946A (enExample)
AU (1) AU2008218763B2 (enExample)
CA (1) CA2678875A1 (enExample)
WO (1) WO2008103690A2 (enExample)

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US7473678B2 (en) 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
WO2007061889A2 (en) 2005-11-17 2007-05-31 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
ES2427993T3 (es) 2006-02-09 2013-11-05 Biomimetic Therapeutics, Llc Composiciones y métodos para el tratamiento de hueso
WO2008005427A2 (en) 2006-06-30 2008-01-10 Biomimetic Therapeutics, Inc. Pdgf-biomatrix compositions and methods for treating rotator cuff injuries
US9161967B2 (en) 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
EP2462895B1 (en) 2006-11-03 2016-11-02 BioMimetic Therapeutics, LLC Compositions and methods for arthrodetic procedures
CA2715254A1 (en) * 2008-02-07 2009-08-13 Biomimetic Therapeutics, Inc. Compositions and methods for distraction osteogenesis
JP5966129B2 (ja) * 2011-01-31 2016-08-10 オリンパス株式会社 免疫賦活剤
MX2017004520A (es) 2014-10-14 2018-03-15 Lynch Samuel Composiciones para tratar heridas.
GB2549714A (en) * 2016-04-25 2017-11-01 Pharmaceutical Business Consultants Ltd Vascularity affinity precursor structure for musculo-skeletal tissue healing
JP7117724B2 (ja) * 2018-01-18 2022-08-15 新田ゼラチン株式会社 歯肉および歯槽粘膜の再生促進作用に基づく顎骨壊死、顎骨骨髄炎または抜歯後治癒不全の予防に用いる予防剤
WO2025024276A1 (en) * 2023-07-21 2025-01-30 Mercury Bio, Inc. Production and delivery of therapeutic nucleic acids packaged in yeast extracellular vesicles embedded in biocompatible implant matrices

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CA1260391A (en) * 1985-03-28 1989-09-26 Karl A. Piez Xenogeneic collagen/mineral preparations in bone repair
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US5614206A (en) * 1995-03-07 1997-03-25 Wright Medical Technology, Inc. Controlled dissolution pellet containing calcium sulfate
JP4809963B2 (ja) * 1999-11-11 2011-11-09 オリンパス株式会社 骨補填材
JP2003019195A (ja) * 2000-05-19 2003-01-21 Mmt:Kk 生体用部材
AU2003210996A1 (en) * 2002-02-11 2003-09-04 Zymogenetics, Inc. Materials and methods for preparing dimeric growth factors
WO2003094617A2 (en) * 2002-05-06 2003-11-20 Genentech, Inc. Use of vegf for treating bone defects
ATE418619T1 (de) * 2002-06-14 2009-01-15 Pierce Biotechnology Inc Homogenes assay zum nachweis von enzymaktivität
JP2004159971A (ja) * 2002-11-14 2004-06-10 Hideki Yoshikawa 骨形成用部材およびその製造方法
EP1433489A1 (en) * 2002-12-23 2004-06-30 Degradable Solutions AG Biodegradable porous bone implant with a barrier membrane sealed thereto
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CA2530421C (en) * 2003-06-27 2015-04-21 Ethicon, Incorporated Repair and regeneration of ocular tissue using postpartum-derived cells
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JP2005111130A (ja) * 2003-10-10 2005-04-28 Olympus Corp 骨補填材の製造方法
WO2005067942A1 (en) * 2004-01-16 2005-07-28 Institute Of Nutraceutical Research Pty Ltd Glycosaminoglycan peptides derived from connective tissues and use thereof in the prevention of arthritis and other degenerative medical conditions
US7473678B2 (en) * 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
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WO2007061889A2 (en) * 2005-11-17 2007-05-31 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
ES2427993T3 (es) * 2006-02-09 2013-11-05 Biomimetic Therapeutics, Llc Composiciones y métodos para el tratamiento de hueso
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US9161967B2 (en) * 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
EP2462895B1 (en) * 2006-11-03 2016-11-02 BioMimetic Therapeutics, LLC Compositions and methods for arthrodetic procedures
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Also Published As

Publication number Publication date
EP2125000A2 (en) 2009-12-02
JP2010518946A (ja) 2010-06-03
WO2008103690A2 (en) 2008-08-28
CA2678875A1 (en) 2008-08-28
WO2008103690A3 (en) 2009-09-03
US20100151025A1 (en) 2010-06-17
AU2008218763A1 (en) 2008-08-28

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MK14 Patent ceased section 143(a) (annual fees not paid) or expired