CA2678875A1 - Prevention and treatment for osteonecrosis and osteoradionecrosis of the jaw - Google Patents

Prevention and treatment for osteonecrosis and osteoradionecrosis of the jaw Download PDF

Info

Publication number
CA2678875A1
CA2678875A1 CA002678875A CA2678875A CA2678875A1 CA 2678875 A1 CA2678875 A1 CA 2678875A1 CA 002678875 A CA002678875 A CA 002678875A CA 2678875 A CA2678875 A CA 2678875A CA 2678875 A1 CA2678875 A1 CA 2678875A1
Authority
CA
Canada
Prior art keywords
pdgf
jaw
biocompatible matrix
composition
biocompatible
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002678875A
Other languages
English (en)
French (fr)
Inventor
Samuel E. Lynch
Jeffrey O. Hollinger
Leslie A. Wisner-Lynch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomimetic Therapeutics LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2678875A1 publication Critical patent/CA2678875A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1858Platelet-derived growth factor [PDGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Peptides Or Proteins (AREA)
CA002678875A 2007-02-20 2008-02-20 Prevention and treatment for osteonecrosis and osteoradionecrosis of the jaw Abandoned CA2678875A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89076307P 2007-02-20 2007-02-20
US60/890,763 2007-02-20
PCT/US2008/054354 WO2008103690A2 (en) 2007-02-20 2008-02-20 Prevention and treatment for osteonecrosis and osteoradionecrosis of the jaw using pdgf and a bone matrix

Publications (1)

Publication Number Publication Date
CA2678875A1 true CA2678875A1 (en) 2008-08-28

Family

ID=39710710

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002678875A Abandoned CA2678875A1 (en) 2007-02-20 2008-02-20 Prevention and treatment for osteonecrosis and osteoradionecrosis of the jaw

Country Status (6)

Country Link
US (1) US20100151025A1 (enExample)
EP (1) EP2125000A2 (enExample)
JP (1) JP2010518946A (enExample)
AU (1) AU2008218763B2 (enExample)
CA (1) CA2678875A1 (enExample)
WO (1) WO2008103690A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7473678B2 (en) 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
WO2007061889A2 (en) 2005-11-17 2007-05-31 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
ES2427993T3 (es) 2006-02-09 2013-11-05 Biomimetic Therapeutics, Llc Composiciones y métodos para el tratamiento de hueso
WO2008005427A2 (en) 2006-06-30 2008-01-10 Biomimetic Therapeutics, Inc. Pdgf-biomatrix compositions and methods for treating rotator cuff injuries
US9161967B2 (en) 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
EP2462895B1 (en) 2006-11-03 2016-11-02 BioMimetic Therapeutics, LLC Compositions and methods for arthrodetic procedures
CA2715254A1 (en) * 2008-02-07 2009-08-13 Biomimetic Therapeutics, Inc. Compositions and methods for distraction osteogenesis
JP5966129B2 (ja) * 2011-01-31 2016-08-10 オリンパス株式会社 免疫賦活剤
MX2017004520A (es) 2014-10-14 2018-03-15 Lynch Samuel Composiciones para tratar heridas.
GB2549714A (en) * 2016-04-25 2017-11-01 Pharmaceutical Business Consultants Ltd Vascularity affinity precursor structure for musculo-skeletal tissue healing
JP7117724B2 (ja) * 2018-01-18 2022-08-15 新田ゼラチン株式会社 歯肉および歯槽粘膜の再生促進作用に基づく顎骨壊死、顎骨骨髄炎または抜歯後治癒不全の予防に用いる予防剤
WO2025024276A1 (en) * 2023-07-21 2025-01-30 Mercury Bio, Inc. Production and delivery of therapeutic nucleic acids packaged in yeast extracellular vesicles embedded in biocompatible implant matrices

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1260391A (en) * 1985-03-28 1989-09-26 Karl A. Piez Xenogeneic collagen/mineral preparations in bone repair
DE4120325A1 (de) * 1991-06-20 1992-12-24 Merck Patent Gmbh Implantatwerkstoff
US5614206A (en) * 1995-03-07 1997-03-25 Wright Medical Technology, Inc. Controlled dissolution pellet containing calcium sulfate
JP4809963B2 (ja) * 1999-11-11 2011-11-09 オリンパス株式会社 骨補填材
JP2003019195A (ja) * 2000-05-19 2003-01-21 Mmt:Kk 生体用部材
AU2003210996A1 (en) * 2002-02-11 2003-09-04 Zymogenetics, Inc. Materials and methods for preparing dimeric growth factors
WO2003094617A2 (en) * 2002-05-06 2003-11-20 Genentech, Inc. Use of vegf for treating bone defects
ATE418619T1 (de) * 2002-06-14 2009-01-15 Pierce Biotechnology Inc Homogenes assay zum nachweis von enzymaktivität
JP2004159971A (ja) * 2002-11-14 2004-06-10 Hideki Yoshikawa 骨形成用部材およびその製造方法
EP1433489A1 (en) * 2002-12-23 2004-06-30 Degradable Solutions AG Biodegradable porous bone implant with a barrier membrane sealed thereto
JPWO2004105825A1 (ja) * 2003-01-10 2006-07-20 多木化学株式会社 骨形成用生体材料、該材料を含む注入用製剤、及び該材料を調製するためのキット、並びにこれらを用いる骨形成方法
ES2269973T3 (es) * 2003-02-13 2007-04-01 Synthes Ag Chur Mezcla inyectable para sustituir un tejido oseo.
CA2530421C (en) * 2003-06-27 2015-04-21 Ethicon, Incorporated Repair and regeneration of ocular tissue using postpartum-derived cells
US20070270489A1 (en) * 2003-07-25 2007-11-22 Ono Pharmaceutical Co., Ltd. Remedy for Cartilage-Related Diseases
JP2005111130A (ja) * 2003-10-10 2005-04-28 Olympus Corp 骨補填材の製造方法
WO2005067942A1 (en) * 2004-01-16 2005-07-28 Institute Of Nutraceutical Research Pty Ltd Glycosaminoglycan peptides derived from connective tissues and use thereof in the prevention of arthritis and other degenerative medical conditions
US7473678B2 (en) * 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
JP2006320442A (ja) * 2005-05-18 2006-11-30 Toshiba Ceramics Co Ltd リン酸カルシウム系骨補填材
WO2007061889A2 (en) * 2005-11-17 2007-05-31 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
ES2427993T3 (es) * 2006-02-09 2013-11-05 Biomimetic Therapeutics, Llc Composiciones y métodos para el tratamiento de hueso
US7833270B2 (en) * 2006-05-05 2010-11-16 Warsaw Orthopedic, Inc Implant depots to deliver growth factors to treat osteoporotic bone
WO2008005427A2 (en) * 2006-06-30 2008-01-10 Biomimetic Therapeutics, Inc. Pdgf-biomatrix compositions and methods for treating rotator cuff injuries
US9161967B2 (en) * 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
EP2462895B1 (en) * 2006-11-03 2016-11-02 BioMimetic Therapeutics, LLC Compositions and methods for arthrodetic procedures
WO2008100442A1 (en) * 2007-02-09 2008-08-21 Biomet Biologics, Inc. Treatment of tissue defects with a therapeutic composition
CN104623669A (zh) * 2007-08-22 2015-05-20 斯丹姆涅恩有限公司 含细胞因子溶液的新组合物
CA2715254A1 (en) * 2008-02-07 2009-08-13 Biomimetic Therapeutics, Inc. Compositions and methods for distraction osteogenesis
CN102231992B (zh) * 2008-09-09 2015-05-20 生物模拟治疗公司 用于治疗肌腱和韧带损伤的血小板衍生生长因子的组合物和方法
EP2376106A4 (en) * 2008-12-19 2013-01-09 Biomimetic Therapeutics Inc BONE TRANSPLANTS WITH REDUCED PROTEASE EFFECT AND SELECTION AND APPLICATION PROCEDURES
JP2012519556A (ja) * 2009-03-05 2012-08-30 バイオミメティック セラピューティクス, インコーポレイテッド 骨軟骨欠損を治療するための血小板由来増殖因子組成物および方法

Also Published As

Publication number Publication date
AU2008218763B2 (en) 2013-10-24
EP2125000A2 (en) 2009-12-02
JP2010518946A (ja) 2010-06-03
WO2008103690A2 (en) 2008-08-28
WO2008103690A3 (en) 2009-09-03
US20100151025A1 (en) 2010-06-17
AU2008218763A1 (en) 2008-08-28

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20140220