AU2007322346A1 - Polypeptide ligands for targeting cartilage and methods of use thereof - Google Patents

Polypeptide ligands for targeting cartilage and methods of use thereof Download PDF

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Publication number
AU2007322346A1
AU2007322346A1 AU2007322346A AU2007322346A AU2007322346A1 AU 2007322346 A1 AU2007322346 A1 AU 2007322346A1 AU 2007322346 A AU2007322346 A AU 2007322346A AU 2007322346 A AU2007322346 A AU 2007322346A AU 2007322346 A1 AU2007322346 A1 AU 2007322346A1
Authority
AU
Australia
Prior art keywords
polypeptide
seq
cartilage
therapeutic agent
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2007322346A
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English (en)
Inventor
Jeffrey A. Hubbell
Dominique A. Rothenfluh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
École Polytechnique Fédérale de Lausanne
Original Assignee
École Polytechnique Fédérale de Lausanne
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by École Polytechnique Fédérale de Lausanne filed Critical École Polytechnique Fédérale de Lausanne
Publication of AU2007322346A1 publication Critical patent/AU2007322346A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2007322346A 2006-10-10 2007-10-09 Polypeptide ligands for targeting cartilage and methods of use thereof Abandoned AU2007322346A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/545,819 US7592009B2 (en) 2006-10-10 2006-10-10 Polypeptide ligands for targeting cartilage and methods of use thereof
US11/545,819 2006-10-10
PCT/US2007/021529 WO2008063291A2 (en) 2006-10-10 2007-10-09 Polypeptide ligands for targeting cartilage and methods of use thereof

Publications (1)

Publication Number Publication Date
AU2007322346A1 true AU2007322346A1 (en) 2008-05-29

Family

ID=39417214

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007322346A Abandoned AU2007322346A1 (en) 2006-10-10 2007-10-09 Polypeptide ligands for targeting cartilage and methods of use thereof

Country Status (7)

Country Link
US (2) US7592009B2 (enExample)
EP (1) EP2084275A4 (enExample)
JP (1) JP2010505444A (enExample)
AU (1) AU2007322346A1 (enExample)
CA (1) CA2665839A1 (enExample)
IL (1) IL198120A0 (enExample)
WO (1) WO2008063291A2 (enExample)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2008056623A1 (ja) * 2006-11-09 2010-02-25 第一三共株式会社 核酸導入用組成物
HUE044239T2 (hu) 2008-03-27 2019-10-28 Purdue Research Foundation Kollagén-kötõ szintetikus peptidoglikánok, elõállításuk és alkalmazási eljárásaik
US8868149B2 (en) * 2009-07-30 2014-10-21 Oxitone Medical Ltd. Photoplethysmography device and method
CA2769206A1 (en) 2009-07-31 2011-02-03 Amgen Inc. Polypeptides that bind tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods
US10487148B2 (en) 2010-01-28 2019-11-26 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for treating aging-associated impairments
US20160208011A1 (en) 2010-01-28 2016-07-21 The Board Of Trustees Of The Leland Stanford Junior University Ccr3 modulation in the treatment of aging-associated impairments, and compositions for practicing the same
WO2017120461A1 (en) 2016-01-08 2017-07-13 The Board Of Trustees Of The Leland Stanford Junior University Ccr3 modulation in the treatment of aging-associated impairments, and compositions for practicing the same
WO2011097342A1 (en) * 2010-02-04 2011-08-11 University Of Utah Research Foundation Hydrophobically-modified hyaluronan and methods of making and using thereof
US8524662B2 (en) 2010-12-28 2013-09-03 Depuy Mitek, Llc Compositions and methods for treating joints
US8398611B2 (en) 2010-12-28 2013-03-19 Depuy Mitek, Inc. Compositions and methods for treating joints
US8455436B2 (en) 2010-12-28 2013-06-04 Depuy Mitek, Llc Compositions and methods for treating joints
US9173919B2 (en) 2011-02-16 2015-11-03 Purdue Research Foundation Collagen-targeted nanoparticles
US9161968B2 (en) 2011-04-08 2015-10-20 The Board Of Trustees Of The Leland Stanford Junior University Methods of neuroprotection involving macrophage colony stimulating factor receptor agonists
US9217016B2 (en) 2011-05-24 2015-12-22 Symic Ip, Llc Hyaluronic acid-binding synthetic peptidoglycans, preparation, and methods of use
US8623839B2 (en) 2011-06-30 2014-01-07 Depuy Mitek, Llc Compositions and methods for stabilized polysaccharide formulations
WO2014063102A1 (en) * 2012-10-19 2014-04-24 Cornell University Biomimetic boundary lubricants for articular cartilage
JP2016511747A (ja) 2013-01-04 2016-04-21 マサチューセッツ インスティテュート オブ テクノロジー ナノ粒子表面結合に基づく薬物の組織への送達
EP2970509B1 (en) * 2013-03-15 2020-05-13 Purdue Research Foundation Extracellular matrix-binding synthetic peptidoglycans
WO2015009787A1 (en) 2013-07-19 2015-01-22 The Johns Hopkins University Biomaterials comprising hyaluronic acid binding peptides and extracellular matrix binding peptides for hyaluronic acid retention and tissue engineering applications
US11559580B1 (en) 2013-09-17 2023-01-24 Blaze Bioscience, Inc. Tissue-homing peptide conjugates and methods of use thereof
WO2015075699A1 (en) * 2013-11-25 2015-05-28 Sanofi Dotam derivatives for therapeutic use
EP3079708A4 (en) 2013-12-09 2017-08-30 The Board of Trustees of the Leland Stanford Junior University Methods and compositions for treating aging-associated conditions
US10905779B2 (en) 2013-12-09 2021-02-02 The Board Of Trustees Of The Leland Stanford Junior University Methods for screening human blood products comprising plasma using immunocompromised rodent models
WO2015164822A1 (en) 2014-04-25 2015-10-29 Purdue Research Foundation Collagen binding synthetic peptidoglycans for treatment of endothelial dysfunction
CA2956726C (en) 2014-08-27 2023-06-06 Amgen Inc. Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods
US9682099B2 (en) 2015-01-20 2017-06-20 DePuy Synthes Products, Inc. Compositions and methods for treating joints
PT3307296T (pt) * 2015-06-15 2022-01-07 Univ Leland Stanford Junior Timp2 para uso no tratamento de condições associadas ao envelhecimento
CA2994865A1 (en) 2015-09-09 2017-03-16 Fred Hutchinson Cancer Research Center Cartilage-homing peptides
EP3426265B1 (en) 2016-04-28 2021-09-22 Alkahest, Inc. Plasma fractions as therapy for tumor growth and progression
IL304946A (en) 2016-08-18 2023-10-01 Alkahest Inc Blood plasma fractions as a treatment for cognitive disorders associated with aging
EA039316B1 (ru) 2016-10-24 2022-01-12 Алкахест, Инк. Фракции плазмы крови в качестве лечения когнитивных расстройств, связанных со старением
CA3049262A1 (en) 2017-01-18 2018-07-26 Fred Hutchinson Cancer Research Center Peptide compositions and methods of use thereof for disrupting tead interactions
CN110475565A (zh) 2017-03-16 2019-11-19 光明之火生物科学公司 软骨归巢肽缀合物及其使用方法
BR112019022402A2 (pt) 2017-04-26 2020-05-19 Alkahest Inc regime de dosagem para tratamento de comprometimentos cognitivo e motor com plasma sanguíneo e produtos de plasma sanguíneo
US11040068B2 (en) 2017-04-26 2021-06-22 Alkahest, Inc. Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products
WO2018232122A1 (en) 2017-06-15 2018-12-20 Blaze Bioscience, Inc. Renal-homing peptide conjugates and methods of use thereof
WO2019010484A2 (en) 2017-07-07 2019-01-10 Symic Ip, Llc SYNTHETIC BIOCONJUGATES
JP7386161B2 (ja) 2017-12-19 2023-11-24 ブレイズ バイオサイエンス， インコーポレイテッド 腫瘍ホーミング及び細胞透過性ペプチド免疫抗がん剤複合体、ならびにそれらの使用方法
CA3093588A1 (en) * 2018-03-16 2019-09-19 Blaze Bioscience, Inc. Truncated cartilage-homing peptides and peptide complexes and methods of use thereof
CA3115298A1 (en) 2018-10-12 2020-04-16 Theradaptive, Inc. Polypeptides including a beta-tricalcium phosphate-binding sequence and uses thereof
MX2021004755A (es) 2018-10-26 2021-06-08 Alkahest Inc Uso de plasma y fracciones de plasma para mejorar el dolor, la cicatrizacion de heridas y la recuperacion posoperatoria.
US20230026969A1 (en) * 2019-12-03 2023-01-26 China Medical University Oligopeptide, Testing Kit Thereof And Medical Composition Thereof
BR112022020809A2 (pt) 2020-04-15 2023-02-23 Theradaptive Inc Composições e métodos para entrega terapêutica direcionada ao osso

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2090925A (en) * 1935-11-25 1937-08-24 Platt Brothers & Co Ltd Apparatus for opening and cleaning flax straw and such like fibrous materials
US5185444A (en) * 1985-03-15 1993-02-09 Anti-Gene Deveopment Group Uncharged morpolino-based polymers having phosphorous containing chiral intersubunit linkages
JP2528107B2 (ja) * 1985-03-15 1996-08-28 サマ−トン，ジエ−ムス ポリヌクレオチド測定試薬と方法
US5227165A (en) * 1989-11-13 1993-07-13 Nova Pharmaceutical Corporation Liposphere delivery systems for local anesthetics
US5410016A (en) * 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US6562596B1 (en) 1993-10-06 2003-05-13 Amgen Inc. Tissue inhibitor of metalloproteinase type three (TIMP-3) composition and methods
WO1997022371A1 (en) * 1995-12-18 1997-06-26 Collagen Corporation Crosslinked polymer compositions and methods for their use
CA2267930A1 (en) * 1996-10-09 1998-04-16 Nobuyuki Takechi A method for producing a microparticle
US6224794B1 (en) * 1998-05-06 2001-05-01 Angiotech Pharmaceuticals, Inc. Methods for microsphere production
US20090087878A9 (en) * 1999-05-06 2009-04-02 La Rosa Thomas J Nucleic acid molecules associated with plants
JP2003516760A (ja) * 1999-12-02 2003-05-20 ユニヴァーシティー オブ ダンディー プロテインキナーゼ調節
US20110131679A2 (en) * 2000-04-19 2011-06-02 Thomas La Rosa Rice Nucleic Acid Molecules and Other Molecules Associated with Plants and Uses Thereof for Plant Improvement
JP2004520803A (ja) * 2000-04-21 2004-07-15 コリクサ コーポレイション 尋常性挫瘡の治療および診断のための組成物および方法
US7630836B2 (en) * 2001-05-30 2009-12-08 The Kitasato Institute Polynucleotides
US7314974B2 (en) * 2002-02-21 2008-01-01 Monsanto Technology, Llc Expression of microbial proteins in plants for production of plants with improved properties
JP2006515985A (ja) * 2002-10-23 2006-06-15 エクセリクシス， インク． 分枝形態形成のモディファイヤーとしてのｍｂｍ及び使用方法

Also Published As

Publication number Publication date
CA2665839A1 (en) 2008-05-29
EP2084275A4 (en) 2012-01-04
IL198120A0 (en) 2011-08-01
JP2010505444A (ja) 2010-02-25
EP2084275A2 (en) 2009-08-05
WO2008063291A2 (en) 2008-05-29
US20100080850A1 (en) 2010-04-01
US7592009B2 (en) 2009-09-22
WO2008063291A3 (en) 2008-10-02
US20080118523A1 (en) 2008-05-22

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MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period