AU2007322346A1 - Polypeptide ligands for targeting cartilage and methods of use thereof - Google Patents

Polypeptide ligands for targeting cartilage and methods of use thereof Download PDF

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Publication number
AU2007322346A1
AU2007322346A1 AU2007322346A AU2007322346A AU2007322346A1 AU 2007322346 A1 AU2007322346 A1 AU 2007322346A1 AU 2007322346 A AU2007322346 A AU 2007322346A AU 2007322346 A AU2007322346 A AU 2007322346A AU 2007322346 A1 AU2007322346 A1 AU 2007322346A1
Authority
AU
Australia
Prior art keywords
polypeptide
seq
cartilage
therapeutic agent
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2007322346A
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English (en)
Inventor
Jeffrey A. Hubbell
Dominique A. Rothenfluh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ecole Polytechnique Federale de Lausanne EPFL
Original Assignee
Ecole Polytechnique Federale de Lausanne EPFL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ecole Polytechnique Federale de Lausanne EPFL filed Critical Ecole Polytechnique Federale de Lausanne EPFL
Publication of AU2007322346A1 publication Critical patent/AU2007322346A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2007322346A 2006-10-10 2007-10-09 Polypeptide ligands for targeting cartilage and methods of use thereof Abandoned AU2007322346A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/545,819 2006-10-10
US11/545,819 US7592009B2 (en) 2006-10-10 2006-10-10 Polypeptide ligands for targeting cartilage and methods of use thereof
PCT/US2007/021529 WO2008063291A2 (en) 2006-10-10 2007-10-09 Polypeptide ligands for targeting cartilage and methods of use thereof

Publications (1)

Publication Number Publication Date
AU2007322346A1 true AU2007322346A1 (en) 2008-05-29

Family

ID=39417214

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007322346A Abandoned AU2007322346A1 (en) 2006-10-10 2007-10-09 Polypeptide ligands for targeting cartilage and methods of use thereof

Country Status (7)

Country Link
US (2) US7592009B2 (enExample)
EP (1) EP2084275A4 (enExample)
JP (1) JP2010505444A (enExample)
AU (1) AU2007322346A1 (enExample)
CA (1) CA2665839A1 (enExample)
IL (1) IL198120A0 (enExample)
WO (1) WO2008063291A2 (enExample)

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WO2017120461A1 (en) 2016-01-08 2017-07-13 The Board Of Trustees Of The Leland Stanford Junior University Ccr3 modulation in the treatment of aging-associated impairments, and compositions for practicing the same
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US8524662B2 (en) 2010-12-28 2013-09-03 Depuy Mitek, Llc Compositions and methods for treating joints
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US9161968B2 (en) 2011-04-08 2015-10-20 The Board Of Trustees Of The Leland Stanford Junior University Methods of neuroprotection involving macrophage colony stimulating factor receptor agonists
HUE031596T2 (en) 2011-05-24 2017-07-28 Symic Ip Llc Synthetic peptidoglycans that bind hyaluronic acid, their production and use
US8623839B2 (en) 2011-06-30 2014-01-07 Depuy Mitek, Llc Compositions and methods for stabilized polysaccharide formulations
CN104870020A (zh) * 2012-10-19 2015-08-26 康奈尔大学 用于关节软骨的仿生型界面润滑剂
JP2016511747A (ja) 2013-01-04 2016-04-21 マサチューセッツ インスティテュート オブ テクノロジー ナノ粒子表面結合に基づく薬物の組織への送達
WO2014144969A1 (en) 2013-03-15 2014-09-18 Purdue Research Foundation Extracellular matrix-binding synthetic peptidoglycans
US10231991B2 (en) 2013-07-19 2019-03-19 The Johns Hopkins University Biomaterials comprising hyaluronic acid binding peptides and extracellular matrix binding peptides for hyaluronic acid retention and tissue engineering applications
US11559580B1 (en) 2013-09-17 2023-01-24 Blaze Bioscience, Inc. Tissue-homing peptide conjugates and methods of use thereof
WO2015075699A1 (en) * 2013-11-25 2015-05-28 Sanofi Dotam derivatives for therapeutic use
US10905779B2 (en) 2013-12-09 2021-02-02 The Board Of Trustees Of The Leland Stanford Junior University Methods for screening human blood products comprising plasma using immunocompromised rodent models
CN106163530A (zh) 2013-12-09 2016-11-23 小利兰·斯坦福大学托管委员会 用于治疗衰老相关病症的方法和组合物
WO2015164822A1 (en) 2014-04-25 2015-10-29 Purdue Research Foundation Collagen binding synthetic peptidoglycans for treatment of endothelial dysfunction
JP6672257B2 (ja) 2014-08-27 2020-03-25 アムジエン・インコーポレーテツド 組織メタロプロテイナーゼ阻害物質３型（ｔｉｍｐ−３）の変異体、組成物、及び方法
US9682099B2 (en) 2015-01-20 2017-06-20 DePuy Synthes Products, Inc. Compositions and methods for treating joints
EA201890020A1 (ru) * 2015-06-15 2018-05-31 Зе Боард Оф Трастиз Оф Зе Леланд Стэнфорд Джуниор Юниверсити Способы и композиции для лечения ассоциированных со старением состояний
JP6966424B2 (ja) * 2015-09-09 2021-11-17 フレッド ハッチンソン キャンサー リサーチ センター 軟骨ホーミングペプチド
US10245285B2 (en) 2016-04-28 2019-04-02 Alkahest, Inc. Blood plasma and plasma fractions as therapy for tumor growth and progression
EA039316B1 (ru) 2016-10-24 2022-01-12 Алкахест, Инк. Фракции плазмы крови в качестве лечения когнитивных расстройств, связанных со старением
WO2018136614A1 (en) 2017-01-18 2018-07-26 Fred Hutchinson Cancer Research Center Peptide compositions and methods of use thereof for disrupting tead interactions
CN110475565A (zh) 2017-03-16 2019-11-19 光明之火生物科学公司 软骨归巢肽缀合物及其使用方法
US11040068B2 (en) 2017-04-26 2021-06-22 Alkahest, Inc. Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products
IL270125B2 (en) 2017-04-26 2024-02-01 Alkahest Inc Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products
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CA3086040A1 (en) 2017-12-19 2019-06-27 Blaze Bioscience, Inc. Tumor homing and cell penetrating peptide-immuno-oncology agent complexes and methods of use thereof
WO2019178573A1 (en) * 2018-03-16 2019-09-19 Blaze Bioscience, Inc. Truncated cartilage-homing peptides and peptide complexes and methods of use thereof
CA3115298A1 (en) 2018-10-12 2020-04-16 Theradaptive, Inc. Polypeptides including a beta-tricalcium phosphate-binding sequence and uses thereof
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TWI783314B (zh) * 2019-12-03 2022-11-11 中國醫藥大學 寡胜肽，其檢測套組，其醫藥組合物與醫藥組合物的用途
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Also Published As

Publication number Publication date
JP2010505444A (ja) 2010-02-25
EP2084275A4 (en) 2012-01-04
WO2008063291A3 (en) 2008-10-02
CA2665839A1 (en) 2008-05-29
US20080118523A1 (en) 2008-05-22
US20100080850A1 (en) 2010-04-01
WO2008063291A2 (en) 2008-05-29
US7592009B2 (en) 2009-09-22
EP2084275A2 (en) 2009-08-05
IL198120A0 (en) 2011-08-01

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Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period