AU2007322346A1 - Polypeptide ligands for targeting cartilage and methods of use thereof - Google Patents

Polypeptide ligands for targeting cartilage and methods of use thereof Download PDF

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Publication number
AU2007322346A1
AU2007322346A1 AU2007322346A AU2007322346A AU2007322346A1 AU 2007322346 A1 AU2007322346 A1 AU 2007322346A1 AU 2007322346 A AU2007322346 A AU 2007322346A AU 2007322346 A AU2007322346 A AU 2007322346A AU 2007322346 A1 AU2007322346 A1 AU 2007322346A1
Authority
AU
Australia
Prior art keywords
polypeptide
seq
cartilage
therapeutic agent
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2007322346A
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English (en)
Inventor
Jeffrey A. Hubbell
Dominique A. Rothenfluh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ecole Polytechnique Federale de Lausanne EPFL
Original Assignee
Ecole Polytechnique Federale de Lausanne EPFL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ecole Polytechnique Federale de Lausanne EPFL filed Critical Ecole Polytechnique Federale de Lausanne EPFL
Publication of AU2007322346A1 publication Critical patent/AU2007322346A1/en
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2007322346A 2006-10-10 2007-10-09 Polypeptide ligands for targeting cartilage and methods of use thereof Abandoned AU2007322346A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/545,819 US7592009B2 (en) 2006-10-10 2006-10-10 Polypeptide ligands for targeting cartilage and methods of use thereof
US11/545,819 2006-10-10
PCT/US2007/021529 WO2008063291A2 (en) 2006-10-10 2007-10-09 Polypeptide ligands for targeting cartilage and methods of use thereof

Publications (1)

Publication Number Publication Date
AU2007322346A1 true AU2007322346A1 (en) 2008-05-29

Family

ID=39417214

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007322346A Abandoned AU2007322346A1 (en) 2006-10-10 2007-10-09 Polypeptide ligands for targeting cartilage and methods of use thereof

Country Status (7)

Country Link
US (2) US7592009B2 (OSRAM)
EP (1) EP2084275A4 (OSRAM)
JP (1) JP2010505444A (OSRAM)
AU (1) AU2007322346A1 (OSRAM)
CA (1) CA2665839A1 (OSRAM)
IL (1) IL198120A0 (OSRAM)
WO (1) WO2008063291A2 (OSRAM)

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US10487148B2 (en) 2010-01-28 2019-11-26 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for treating aging-associated impairments
US10626399B2 (en) 2010-01-28 2020-04-21 The Board Of Trustees Of The Leland Stanford Junior University Methods of treating cognitive symptoms of an aging-associated impairment by modulating C-C chemokine receptor type 3 (CCR3)
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US8398611B2 (en) 2010-12-28 2013-03-19 Depuy Mitek, Inc. Compositions and methods for treating joints
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US8524662B2 (en) 2010-12-28 2013-09-03 Depuy Mitek, Llc Compositions and methods for treating joints
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US9161968B2 (en) 2011-04-08 2015-10-20 The Board Of Trustees Of The Leland Stanford Junior University Methods of neuroprotection involving macrophage colony stimulating factor receptor agonists
PT2714718T (pt) 2011-05-24 2017-04-19 Symic Ip Llc Preparação e métodos de utilização de peptidoglicanas sintéticas que se ligam a ácido hialurónico
US8623839B2 (en) 2011-06-30 2014-01-07 Depuy Mitek, Llc Compositions and methods for stabilized polysaccharide formulations
CN104870020A (zh) * 2012-10-19 2015-08-26 康奈尔大学 用于关节软骨的仿生型界面润滑剂
EP2941243A4 (en) * 2013-01-04 2016-09-14 Massachusetts Inst Technology SURFACE BINDING IN THE ADMINISTRATION OF A MEDICAMENT ON NANOPARTICLE BASE IN A TISSUE
JP6603650B2 (ja) 2013-03-15 2019-11-06 パーデュー・リサーチ・ファウンデーション 細胞外マトリックス結合性合成ペプチドグリカン
US10231991B2 (en) 2013-07-19 2019-03-19 The Johns Hopkins University Biomaterials comprising hyaluronic acid binding peptides and extracellular matrix binding peptides for hyaluronic acid retention and tissue engineering applications
US11559580B1 (en) 2013-09-17 2023-01-24 Blaze Bioscience, Inc. Tissue-homing peptide conjugates and methods of use thereof
US20170050988A1 (en) * 2013-11-25 2017-02-23 Sanofi Dotam derivatives for therapeutic use
WO2015088915A1 (en) 2013-12-09 2015-06-18 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for treating aging-associated conditions
US10905779B2 (en) 2013-12-09 2021-02-02 The Board Of Trustees Of The Leland Stanford Junior University Methods for screening human blood products comprising plasma using immunocompromised rodent models
US10772931B2 (en) 2014-04-25 2020-09-15 Purdue Research Foundation Collagen binding synthetic peptidoglycans for treatment of endothelial dysfunction
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US9682099B2 (en) 2015-01-20 2017-06-20 DePuy Synthes Products, Inc. Compositions and methods for treating joints
ES2902467T3 (es) * 2015-06-15 2022-03-28 Univ Leland Stanford Junior TIMP2 para su uso en el tratamiento de afecciones asociadas al envejecimiento
EP3347035A4 (en) 2015-09-09 2019-05-01 Fred Hutchinson Cancer Research Center CARTON PEPTIDES
EP3995141B1 (en) 2016-04-28 2024-01-03 Alkahest, Inc. Plasma fractions as therapy for thymic cancer
US10525107B2 (en) 2016-08-18 2020-01-07 Alkahest, Inc. Blood plasma fractions as a treatment for aging-associated cognitive disorders
JP7191025B2 (ja) 2017-01-18 2022-12-16 フレッド ハッチンソン キャンサー センター Tead相互作用を妨害するためのペプチド組成物およびその使用方法
JP7280193B2 (ja) * 2017-03-16 2023-05-23 ブレイズ バイオサイエンス, インコーポレイテッド 軟骨ホーミングペプチドコンジュゲート及びその使用方法
AU2018257921B2 (en) 2017-04-26 2024-06-06 Alkahest, Inc. Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products
US11040068B2 (en) 2017-04-26 2021-06-22 Alkahest, Inc. Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products
US11331393B2 (en) 2017-06-15 2022-05-17 Blaze Bioscience, Inc. Renal-homing peptide conjugates and methods of use thereof
EP3648774A4 (en) 2017-07-07 2021-04-21 Symic IP, LLC SYNTHETIC BIOCONJUGATES
US11866466B2 (en) 2017-12-19 2024-01-09 Blaze Bioscience, Inc. Tumor homing and cell penetrating peptide-immuno-oncology agent complexes and methods of use thereof
CN112105375A (zh) * 2018-03-16 2020-12-18 光明之火生物科学公司 截短的软骨归巢肽和肽复合物及其使用方法
EP4420723A3 (en) 2018-10-12 2024-12-04 Theradaptive, Inc. Polypeptides including a beta-tricalcium phosphate-binding sequence and uses thereof
MX2021004755A (es) 2018-10-26 2021-06-08 Alkahest Inc Uso de plasma y fracciones de plasma para mejorar el dolor, la cicatrizacion de heridas y la recuperacion posoperatoria.
KR20220122648A (ko) * 2019-12-03 2022-09-02 차이나 메디칼 유니버시티 올리고펩티드, 이의 테스트 키트, 및 이의 의약 조성물
AU2021254751B2 (en) 2020-04-15 2025-01-30 Theradaptive, Inc. Compositions and methods for targeted therapeutic delivery to bone

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Also Published As

Publication number Publication date
CA2665839A1 (en) 2008-05-29
WO2008063291A2 (en) 2008-05-29
US20100080850A1 (en) 2010-04-01
US20080118523A1 (en) 2008-05-22
IL198120A0 (en) 2011-08-01
US7592009B2 (en) 2009-09-22
EP2084275A2 (en) 2009-08-05
EP2084275A4 (en) 2012-01-04
JP2010505444A (ja) 2010-02-25
WO2008063291A3 (en) 2008-10-02

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Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period