AU2007307254A1 - Stabilized therapeutic small helical antiviral peptides - Google Patents

Stabilized therapeutic small helical antiviral peptides Download PDF

Info

Publication number
AU2007307254A1
AU2007307254A1 AU2007307254A AU2007307254A AU2007307254A1 AU 2007307254 A1 AU2007307254 A1 AU 2007307254A1 AU 2007307254 A AU2007307254 A AU 2007307254A AU 2007307254 A AU2007307254 A AU 2007307254A AU 2007307254 A1 AU2007307254 A1 AU 2007307254A1
Authority
AU
Australia
Prior art keywords
peptide
amino acids
capsid
mammal
containing virus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2007307254A
Other languages
English (en)
Inventor
Asim Kumar Debnath
Hongtao Zhang
Qian Zhao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
New York Blood Center Inc
Original Assignee
New York Blood Center Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York Blood Center Inc filed Critical New York Blood Center Inc
Publication of AU2007307254A1 publication Critical patent/AU2007307254A1/en
Priority to AU2012200580A priority Critical patent/AU2012200580A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU2007307254A 2006-10-05 2007-10-02 Stabilized therapeutic small helical antiviral peptides Abandoned AU2007307254A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2012200580A AU2012200580A1 (en) 2007-10-02 2012-02-02 Stabilized therapeutic small helical antiviral peptides

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US84955106P 2006-10-05 2006-10-05
US60/849,551 2006-10-05
PCT/US2007/021156 WO2008045238A2 (en) 2006-10-05 2007-10-02 Stabilized therapeutic small helical antiviral peptides

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2012200580A Addition AU2012200580A1 (en) 2007-10-02 2012-02-02 Stabilized therapeutic small helical antiviral peptides

Publications (1)

Publication Number Publication Date
AU2007307254A1 true AU2007307254A1 (en) 2008-04-17

Family

ID=39283347

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007307254A Abandoned AU2007307254A1 (en) 2006-10-05 2007-10-02 Stabilized therapeutic small helical antiviral peptides

Country Status (8)

Country Link
US (1) US8940864B2 (enExample)
EP (2) EP2073829B1 (enExample)
JP (1) JP2010505831A (enExample)
AU (1) AU2007307254A1 (enExample)
CA (1) CA2665186A1 (enExample)
ES (1) ES2387827T3 (enExample)
WO (1) WO2008045238A2 (enExample)
ZA (1) ZA200901248B (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8937154B2 (en) 2006-10-05 2015-01-20 New York Blood Center, Inc. Stabilized therapeutic small helical antiviral peptides
PL2118123T3 (pl) 2007-01-31 2016-06-30 Dana Farber Cancer Inst Inc Stabilizowane peptydy p53 i ich zastosowania
JP5631201B2 (ja) 2007-03-28 2014-11-26 プレジデント アンド フェローズ オブ ハーバード カレッジ ステッチングされたポリペプチド
CA2725227A1 (en) * 2008-05-06 2009-11-12 Asim Kumar Debnath Antiviral cell penetrating peptides
CA2737916A1 (en) * 2008-09-22 2010-03-25 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
AU2010204648B2 (en) 2009-01-14 2016-09-01 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
KR102104762B1 (ko) 2010-08-13 2020-04-24 에일러론 테라퓨틱스 인코포레이티드 펩티도미메틱 거대고리
EP2768518A4 (en) 2011-10-18 2015-05-27 Aileron Therapeutics Inc PEPTIDOMIMETIC MACROCYCLES
CA2864120A1 (en) 2012-02-15 2013-08-22 Aileron Therapeutics, Inc. Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
RU2642299C2 (ru) 2012-02-15 2018-01-24 Эйлерон Терапьютикс, Инк. P53 пептидомиметические макроциклы
BR112015009470A2 (pt) 2012-11-01 2019-12-17 Aileron Therapeutics Inc aminoácidos dissubstituídos e seus métodos de preparação e uso
US11039620B2 (en) 2014-02-19 2021-06-22 Corning Incorporated Antimicrobial glass compositions, glasses and polymeric articles incorporating the same
US9622483B2 (en) 2014-02-19 2017-04-18 Corning Incorporated Antimicrobial glass compositions, glasses and polymeric articles incorporating the same
US11039621B2 (en) 2014-02-19 2021-06-22 Corning Incorporated Antimicrobial glass compositions, glasses and polymeric articles incorporating the same
EP3197478A4 (en) 2014-09-24 2018-05-30 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
CN107106642B (zh) 2014-09-24 2021-02-26 艾瑞朗医疗公司 拟肽大环化合物及其制剂
WO2016085280A1 (ko) * 2014-11-28 2016-06-02 서울대학교산학협력단 세포 투과성 스테이플 펩타이드, 이의 제조방법 및 그 용도
JP2018516844A (ja) 2015-03-20 2018-06-28 エルロン・セラピューティクス・インコーポレイテッドＡｉｌｅｒｏｎ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． ペプチド模倣大環状分子およびその使用
US10059741B2 (en) 2015-07-01 2018-08-28 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
WO2017018595A1 (ko) * 2015-07-28 2017-02-02 동국대학교 산학협력단 이중 스테이플화된 펩타이드 및 이의 용도
EP3347372A4 (en) 2015-09-10 2019-09-04 Aileron Therapeutics, Inc. PEPTIDOMIMETIC MACROCYCLES AS MODULATORS OF MCL-1
US11279734B2 (en) 2017-12-01 2022-03-22 Massachusetts Institute Of Technology Solution-phase affinity selection of inhibitors from combinatorial peptide libraries
US20200102356A1 (en) * 2018-10-01 2020-04-02 NMC Inc. Compositions and Methods for the Treatment of Huanglongbing (HLB) aka Citrus Greening in Citrus Plants
WO2022036049A2 (en) * 2020-08-12 2022-02-17 New York Blood Center, Inc. Antiviral stapled peptides against sars-cov-2

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6187548B1 (en) * 1993-05-23 2001-02-13 Rhone-Poulenc Rorer Pharmaceuticals Inc. Methods using human calcium sensor protein, fragments thereof and DNA encoding same
US6239270B1 (en) * 1993-05-24 2001-05-29 Rhone-Poulenc Rorer S.A. Nucleic acids encoding human calcium sensor protein
US6790950B2 (en) * 1999-04-09 2004-09-14 Pharmacia & Upjohn Company Anti-bacterial vaccine compositions
WO2000061724A2 (en) * 1999-04-09 2000-10-19 Pharmacia & Upjohn Company Anti-bacterial vaccine compositions
US7192713B1 (en) 1999-05-18 2007-03-20 President And Fellows Of Harvard College Stabilized compounds having secondary structure motifs
US6653102B2 (en) * 2000-10-17 2003-11-25 Myriad Genetics, Inc. Nucleic acid encoding a phosphatase 2C that interacts with Fe 65
WO2005044839A2 (en) 2003-11-05 2005-05-19 Dana-Farber Cancer Institute, Inc. Stabilized alpha helical peptides and uses thereof
WO2008008998A2 (en) * 2006-07-13 2008-01-17 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in signaling pathways
WO2008009000A2 (en) * 2006-07-13 2008-01-17 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in signaling pathways
EP2061487A4 (en) * 2006-09-11 2009-12-02 Univ Illinois MODIFIED CUPREDOXIN-DERIVED PEPTIDES AND METHOD FOR THEIR USE
PL2118123T3 (pl) 2007-01-31 2016-06-30 Dana Farber Cancer Inst Inc Stabilizowane peptydy p53 i ich zastosowania
JP5078401B2 (ja) * 2007-03-27 2012-11-21 株式会社Ａｄｅｋａ 防水シート
WO2009042237A2 (en) 2007-09-26 2009-04-02 Dana Farber Cancer Institute Methods and compositions for modulating bcl-2 family polypeptides
JP5788178B2 (ja) 2008-01-23 2015-09-30 ダナ ファーバー キャンサー インスティテュート インコーポレイテッド ウィルス感染症の治療のための組成物及び方法
CA2725227A1 (en) * 2008-05-06 2009-11-12 Asim Kumar Debnath Antiviral cell penetrating peptides
US20110218155A1 (en) 2008-10-10 2011-09-08 Dana-Farber Cancer Institute, Inc. Chemical modulators of pro-apoptotic bax and bcl-2 polypeptides

Also Published As

Publication number Publication date
EP2517720A1 (en) 2012-10-31
US8940864B2 (en) 2015-01-27
EP2073829B1 (en) 2012-06-20
WO2008045238A2 (en) 2008-04-17
ZA200901248B (en) 2010-04-28
EP2073829A4 (en) 2010-03-03
CA2665186A1 (en) 2008-04-17
JP2010505831A (ja) 2010-02-25
WO2008045238A3 (en) 2008-07-24
EP2073829A2 (en) 2009-07-01
ES2387827T3 (es) 2012-10-02
US20100130430A1 (en) 2010-05-27

Similar Documents

Publication Publication Date Title
US8940864B2 (en) Stabilized therapeutic small helical antiviral peptides
Zhang et al. A cell-penetrating helical peptide as a potential HIV-1 inhibitor
US8933019B2 (en) Antiviral cell-penetrating peptides
DK2320927T3 (en) Modified peptides as potent inhibitors of the PSD-95 / NMDA receptor interaction
JP2011522796A5 (enExample)
PT1989220E (pt) Péptidos inibidores de fusão de hiv com propriedades biológicas melhoradas
CN111643656A (zh) 广谱冠状病毒膜融合抑制剂及其抗艾滋病病毒的应用
JPH10502337A (ja) Ｈｉｖの細胞侵入を阻害するための、 ｄｐｐｉｖの基質であるペプチド類縁体、特にｋｐｒ型の該類縁体の複合提示
CN106749558B (zh) 广谱抑制hiv的脂肽、其衍生物、其药物组合物及其用途
US8937154B2 (en) Stabilized therapeutic small helical antiviral peptides
US11186614B2 (en) Anti-HIV peptides
WO2013075594A1 (zh) 人工设计的抗hiv感染多肽、组合物以及用途
CN100455594C (zh) 抑制hiv病毒融合的多肽及其用途
CN117120459A (zh) 抗感染双环肽配体
WO2007068163A1 (en) Hiv fusion inhibitor peptides and use thereof
AU2012200580A1 (en) Stabilized therapeutic small helical antiviral peptides
WO2012139519A1 (zh) 环肽及其医药用途
CA2766417A1 (en) Stabilized therapeutic small helical antiviral peptides
Cai et al. Peptides and peptidomimetics as tools to probe protein-protein interactions–disruption of HIV-1 gp41 fusion core and fusion inhibitor design
EP2794636A1 (en) Hiv membrane fusion inhibitors
Quagliata et al. Aromatic π-Stacking Stabilizes an α-Helical SARS-CoV-2 MPER Peptide that Mimics the Post-Fusion Spike and Enables Potent Antiviral Activity
WO2016094518A2 (en) Novel cyclic peptides and methods using same
WO2018141089A1 (zh) 广谱抑制hiv的脂肽、其衍生物、其药物组合物及其用途
US20250325672A1 (en) Anti-infective bicyclic peptide ligands
Gómara Elena et al. Importance of structure-based studies for the design of a novel HIV-1 inhibitor peptide

Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application