AU2007299043B2 - Expansion method for adult stem cells from blood, particularly peripheral blood, and relative application in medical field - Google Patents

Expansion method for adult stem cells from blood, particularly peripheral blood, and relative application in medical field Download PDF

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Publication number
AU2007299043B2
AU2007299043B2 AU2007299043A AU2007299043A AU2007299043B2 AU 2007299043 B2 AU2007299043 B2 AU 2007299043B2 AU 2007299043 A AU2007299043 A AU 2007299043A AU 2007299043 A AU2007299043 A AU 2007299043A AU 2007299043 B2 AU2007299043 B2 AU 2007299043B2
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stem cells
treatment
pharmaceutical composition
mammals
adult stem
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AU2007299043A1 (en
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Alessandra Gambacurta
Marco Polettini
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Thankstem Srl
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Thankstem Srl
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0665Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/22Colony stimulating factors (G-CSF, GM-CSF)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Reproductive Health (AREA)
  • Neurology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Gynecology & Obstetrics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
AU2007299043A 2006-09-20 2007-09-11 Expansion method for adult stem cells from blood, particularly peripheral blood, and relative application in medical field Ceased AU2007299043B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITRM2006A000498 2006-09-20
IT000498A ITRM20060498A1 (it) 2006-09-20 2006-09-20 Metodo di espansione di cellule staminali adulte da sangue periferico e relativi usi in campo medico
PCT/EP2007/059531 WO2008034740A1 (en) 2006-09-20 2007-09-11 Expansion method for adult stem cells from blood, particularly peripheral blood, and relative application in medical field

Publications (2)

Publication Number Publication Date
AU2007299043A1 AU2007299043A1 (en) 2008-03-27
AU2007299043B2 true AU2007299043B2 (en) 2013-06-27

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ID=38126399

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AU2007299043A Ceased AU2007299043B2 (en) 2006-09-20 2007-09-11 Expansion method for adult stem cells from blood, particularly peripheral blood, and relative application in medical field

Country Status (20)

Country Link
US (2) US8263400B2 (enExample)
EP (1) EP2076588B1 (enExample)
JP (1) JP5340941B2 (enExample)
KR (1) KR101570446B1 (enExample)
CN (1) CN101553565B (enExample)
AU (1) AU2007299043B2 (enExample)
BR (1) BRPI0715036A2 (enExample)
CA (1) CA2663072C (enExample)
DK (1) DK2076588T3 (enExample)
EA (1) EA019305B1 (enExample)
ES (1) ES2435080T3 (enExample)
HR (1) HRP20131104T1 (enExample)
IL (1) IL197575A (enExample)
IT (1) ITRM20060498A1 (enExample)
MX (1) MX2009003059A (enExample)
PL (1) PL2076588T3 (enExample)
RS (1) RS53039B (enExample)
SI (1) SI2076588T1 (enExample)
WO (1) WO2008034740A1 (enExample)
ZA (1) ZA200901748B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9132116B2 (en) 2004-08-02 2015-09-15 Willowcroft Pharm Inc. Mast cell stabilizers to prevent or treat laminitis
ITUD20080058A1 (it) * 2008-03-18 2009-09-19 Thankstem S R L Kit per la raccolta di sangue, preferibilmente periferico, per la produzione di cellule staminali
WO2010126544A1 (en) * 2009-04-29 2010-11-04 Willowcroft Pharm, Llc Mast cell stabilizers to prevent or treat laminitis
KR101202836B1 (ko) * 2010-08-27 2012-11-20 서울대학교산학협력단 세포응집을 이용한 인간 혈액 유래 혈구 세포괴의 유도와 이를 이용한 혈중 성체줄기세포 및 전구세포의 증폭방법 및 상기의 방법에 의해 제조된 줄기세포
WO2012106367A2 (en) * 2011-01-31 2012-08-09 Royal Daniel F Pluripotent stem cells and method of stimulating and extracting non-embryonic pluripotent stem cells from mammal blood and using reconstituted pluripotent stem cells to treat diseases including chronic obstructive pulmonary disease
BE1020480A5 (nl) 2012-10-01 2013-11-05 Global Stem Cell Technology Werkwijze voor de isolatie van mesenchymale stamcellen uit bloed van zoogdieren, en gebruik ervan.
CN106574247A (zh) * 2014-05-09 2017-04-19 善克思腾(股份)责任有限公司 从全血中扩增成体干细胞的方法
RU2644650C2 (ru) 2014-12-01 2018-02-13 Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" Материал стволовых клеток и способ его получения
WO2016204230A1 (ja) * 2015-06-17 2016-12-22 仁幸 小林 幹細胞投与方法、競走馬または競技馬の症状改善方法、注射用容器および幹細胞注射セット
RU2708329C2 (ru) 2016-05-31 2019-12-05 Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" Материал стволовых клеток, композиции и способы применения
CA3028422A1 (en) * 2016-06-23 2017-12-28 Tithon Biotech, Inc. Cells expressing parathyroid hormone 1 receptor and uses thereof
US11103537B2 (en) 2016-06-23 2021-08-31 Tithon Biotech Inc. Cells expressing parathyroid hormone 1 receptor and uses thereof
BR112021023101A2 (pt) * 2019-05-22 2022-01-04 Thankstem S R L Método para expansão de células-tronco adultas do sangue total

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003083092A1 (en) * 2002-03-28 2003-10-09 Blasticon Biotechnologische Forschung Gmbh Dedifferentiated, programmable stem cells of monocytic origin, and their production and use
WO2004043990A2 (en) * 2002-11-07 2004-05-27 University Of Chicago Human stem cell materials and methods

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1436843A (zh) * 2002-02-08 2003-08-20 刘颉 脐血造血干细胞的制作方法
CN1667119A (zh) * 2004-03-11 2005-09-14 中国人民解放军第二军医大学 一种成体干细胞及其培养方法和用途

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003083092A1 (en) * 2002-03-28 2003-10-09 Blasticon Biotechnologische Forschung Gmbh Dedifferentiated, programmable stem cells of monocytic origin, and their production and use
WO2004043990A2 (en) * 2002-11-07 2004-05-27 University Of Chicago Human stem cell materials and methods

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Zhao Y et al, Proceedings of the National Academy of Sciences, 2003, 100(5):2426-2431 *

Also Published As

Publication number Publication date
EP2076588A1 (en) 2009-07-08
US20120308535A1 (en) 2012-12-06
EA200970294A1 (ru) 2009-10-30
IL197575A0 (en) 2011-08-01
BRPI0715036A2 (pt) 2013-05-28
US20100068189A1 (en) 2010-03-18
RS53039B (sr) 2014-04-30
US8263400B2 (en) 2012-09-11
ITRM20060498A1 (it) 2008-03-21
JP2010504083A (ja) 2010-02-12
JP5340941B2 (ja) 2013-11-13
AU2007299043A1 (en) 2008-03-27
CN101553565B (zh) 2015-05-06
SI2076588T1 (sl) 2013-12-31
PL2076588T3 (pl) 2014-01-31
CA2663072C (en) 2016-01-19
HK1138315A1 (en) 2010-08-20
DK2076588T3 (da) 2013-11-11
KR20090074044A (ko) 2009-07-03
MX2009003059A (es) 2009-04-01
WO2008034740A1 (en) 2008-03-27
CN101553565A (zh) 2009-10-07
KR101570446B1 (ko) 2015-11-27
CA2663072A1 (en) 2008-03-27
IL197575A (en) 2013-06-27
HRP20131104T1 (hr) 2013-12-20
ZA200901748B (en) 2010-03-31
ES2435080T3 (es) 2013-12-18
EA019305B1 (ru) 2014-02-28
EP2076588B1 (en) 2013-08-21

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