AU2007275658B2 - Compositions and methods for the treatment of mucositis - Google Patents

Info

Publication number

AU2007275658B2

AU2007275658B2 AU2007275658A AU2007275658A AU2007275658B2 AU 2007275658 B2 AU2007275658 B2 AU 2007275658B2 AU 2007275658 A AU2007275658 A AU 2007275658A AU 2007275658 A AU2007275658 A AU 2007275658A AU 2007275658 B2 AU2007275658 B2 AU 2007275658B2

Authority

AU

Australia

Prior art keywords

compound

formula

alkyl

mucositis

patient

Prior art date

2006-07-19

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Ceased

Links

• Espacenet
• Global Dossier
• Discuss

• 238000000034 method Methods 0.000 title claims abstract description 78
• 206010028116 Mucosal inflammation Diseases 0.000 title claims abstract description 61
• 201000010927 Mucositis Diseases 0.000 title claims abstract description 61
• 239000000203 mixture Substances 0.000 title description 47
• 238000011282 treatment Methods 0.000 title description 30
• 150000001875 compounds Chemical class 0.000 claims abstract description 225
• 150000003839 salts Chemical class 0.000 claims description 57
• BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 claims description 46
• 229960001138 acetylsalicylic acid Drugs 0.000 claims description 46
• 239000003814 drug Substances 0.000 claims description 43
• 238000001959 radiotherapy Methods 0.000 claims description 26
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• 238000004519 manufacturing process Methods 0.000 claims description 20
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• 238000011161 development Methods 0.000 claims description 11
• 238000011285 therapeutic regimen Methods 0.000 claims description 11
• 230000036269 ulceration Effects 0.000 claims description 11
• 230000017074 necrotic cell death Effects 0.000 claims description 10
• 230000005855 radiation Effects 0.000 claims description 10
• 210000004400 mucous membrane Anatomy 0.000 claims description 9
• 230000002401 inhibitory effect Effects 0.000 claims description 8
• 230000001737 promoting effect Effects 0.000 claims description 8
• 238000002560 therapeutic procedure Methods 0.000 claims description 8
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