AU2007238052B2 - 2,6-substituted-4-monosubstituted amino-pyrimidine as prostaglandin D2 receptor antagonists - Google Patents
2,6-substituted-4-monosubstituted amino-pyrimidine as prostaglandin D2 receptor antagonists Download PDFInfo
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- AU2007238052B2 AU2007238052B2 AU2007238052A AU2007238052A AU2007238052B2 AU 2007238052 B2 AU2007238052 B2 AU 2007238052B2 AU 2007238052 A AU2007238052 A AU 2007238052A AU 2007238052 A AU2007238052 A AU 2007238052A AU 2007238052 B2 AU2007238052 B2 AU 2007238052B2
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- phenyl
- methoxy
- pyrimidin
- dichloro
- acid
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Classifications
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| PCT/US2007/066481 WO2007121280A1 (en) | 2006-04-12 | 2007-04-12 | 2,6-substituted-4-monosubstituted amino-pyrimidine as prostaglandin d2 receptor antagonists |
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| JP5039594B2 (ja) * | 2008-02-08 | 2012-10-03 | 株式会社日立ハイテクノロジーズ | レビュー装置，検査領域設定支援システム、および、欠陥の画像得方法 |
| AR074776A1 (es) * | 2008-12-18 | 2011-02-09 | Sanofi Aventis | Metodo para tratar la degeneracion macular; modulando el sistema inmunitario del paciente |
| TW201204708A (en) * | 2010-03-16 | 2012-02-01 | Aventis Pharma Inc | A substituted pyrimidine as a prostaglandin D2 receptor antagonist |
| EP2547672A1 (en) * | 2010-03-16 | 2013-01-23 | Aventis Pharmaceuticals Inc. | Substituted pyrimidines as prostaglandin d2 receptor antagonists |
| EP2590944B1 (en) | 2010-07-05 | 2015-09-30 | Actelion Pharmaceuticals Ltd. | 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin d2 receptor modulators |
| US8785467B2 (en) * | 2010-09-30 | 2014-07-22 | Merck Sharp & Dohme Corp. | Alkoxy pyrimidine PDE10 inhibitors |
| US9255090B2 (en) | 2011-12-21 | 2016-02-09 | Actelion Pharmaceuticals Ltd. | Heterocyclyl derivatives and their use as prostaglandin D2 receptor modulators |
| US9169270B2 (en) | 2012-07-05 | 2015-10-27 | Actelion Pharmaceuticals Ltd. | 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin D2 receptor modulators |
| EP2912458B1 (en) | 2012-10-24 | 2018-07-18 | NYU Winthrop Hospital | Non-invasive biomarker to identify subjects at risk of preterm delivery |
| RU2673084C2 (ru) * | 2013-11-08 | 2018-11-22 | Киссеи Фармасьютикал Ко., Лтд. | Производное карбоксиметилпиперидина |
| SG11201700777VA (en) | 2014-08-04 | 2017-02-27 | Nuevolution As | Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases |
| CR20180323A (es) | 2015-11-20 | 2018-08-06 | Idorsia Pharmaceuticals Ltd | Derivados de indol n-sustituídos como moduladores de los receptores de pge2 |
| WO2018210992A1 (en) | 2017-05-18 | 2018-11-22 | Idorsia Pharmaceuticals Ltd | Pyrimidine derivatives |
| AU2018268311B2 (en) | 2017-05-18 | 2022-02-10 | Idorsia Pharmaceuticals Ltd | Pyrimidine derivatives as PGE2 receptor modulators |
| US11325899B2 (en) | 2017-05-18 | 2022-05-10 | Idorsia Pharmaceuticals Ltd | Benzofurane and benzothiophene derivatives as PGE2 receptor modulators |
| WO2018210994A1 (en) | 2017-05-18 | 2018-11-22 | Idorsia Pharmaceuticals Ltd | Phenyl derivatives as pge2 receptor modulators |
| US20200264188A1 (en) | 2017-09-13 | 2020-08-20 | Progenity, Inc. | Preeclampsia biomarkers and related systems and methods |
| US20220408745A1 (en) * | 2019-09-13 | 2022-12-29 | Meiji Co., Ltd. | Solid food and solid milk having hole penetrating first face and second face |
| EP4070113A4 (en) | 2019-12-04 | 2023-12-20 | Biora Therapeutics, Inc. | ASSESSMENT OF PREECAMPSIA USING FREE AND DISSOCIATE PLACENTAL GROWTH FACTOR ASSAYS |
| EP4076661A1 (en) | 2019-12-20 | 2022-10-26 | Nuevolution A/S | Compounds active towards nuclear receptors |
| EP4076657A1 (en) | 2019-12-20 | 2022-10-26 | Nuevolution A/S | Compounds active towards nuclear receptors |
| EP4126875A1 (en) | 2020-03-31 | 2023-02-08 | Nuevolution A/S | Compounds active towards nuclear receptors |
| WO2021198955A1 (en) | 2020-03-31 | 2021-10-07 | Nuevolution A/S | Compounds active towards nuclear receptors |
Citations (2)
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|---|---|---|---|---|
| WO2003066047A1 (en) * | 2002-02-05 | 2003-08-14 | Astrazeneca Ab | Use of indole-3-acetic acids in the treatment of asthma, copd and other diseases |
| WO2006044732A2 (en) * | 2004-10-15 | 2006-04-27 | Aventis Pharmaceuticals Inc. | 2, 6-substituted-4-monosubstitutedamino-pyrimidine as prostaglandin d2 receptor antagonists |
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| DE3644799A1 (de) * | 1986-06-04 | 1987-12-10 | Hoechst Ag | Neue pyrimidin-derivate, deren herstellung und verwendung |
| US5047554A (en) * | 1989-04-18 | 1991-09-10 | Pfizer Inc. | 3-substituted-2-oxindole derivatives |
| GT200600457A (es) * | 2005-10-13 | 2007-04-27 | Aventis Pharma Inc | Sal de fosfato dihidrogeno como antagonistas del receptor de prostaglandina d2 |
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2007
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- 2007-04-10 DO DO2007000068A patent/DOP2007000068A/es unknown
- 2007-04-12 EP EP07760526A patent/EP2010503A1/en not_active Withdrawn
- 2007-04-12 MX MX2008011369A patent/MX2008011369A/es active IP Right Grant
- 2007-04-12 WO PCT/US2007/066481 patent/WO2007121280A1/en not_active Ceased
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- 2007-04-12 BR BRPI0710710-2A patent/BRPI0710710A2/pt not_active IP Right Cessation
- 2007-04-12 AU AU2007238052A patent/AU2007238052B2/en not_active Expired - Fee Related
- 2007-04-12 KR KR1020087024764A patent/KR20080108287A/ko not_active Withdrawn
- 2007-04-12 TW TW096112790A patent/TW200815395A/zh unknown
- 2007-04-12 PE PE2007000450A patent/PE20080186A1/es not_active Application Discontinuation
- 2007-04-12 CN CN2007800127354A patent/CN101421252B/zh not_active Expired - Fee Related
- 2007-04-12 UY UY30283A patent/UY30283A1/es not_active Application Discontinuation
- 2007-04-12 CA CA2649083A patent/CA2649083C/en not_active Expired - Fee Related
- 2007-04-12 JP JP2009505615A patent/JP2009533473A/ja not_active Abandoned
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- 2008-10-07 US US12/246,918 patent/US20090036469A1/en not_active Abandoned
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- 2008-10-10 HN HN2008001530A patent/HN2008001530A/es unknown
- 2008-10-14 NO NO20084291A patent/NO20084291L/no not_active Application Discontinuation
- 2008-11-10 MA MA31375A patent/MA30409B1/fr unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003066047A1 (en) * | 2002-02-05 | 2003-08-14 | Astrazeneca Ab | Use of indole-3-acetic acids in the treatment of asthma, copd and other diseases |
| WO2006044732A2 (en) * | 2004-10-15 | 2006-04-27 | Aventis Pharmaceuticals Inc. | 2, 6-substituted-4-monosubstitutedamino-pyrimidine as prostaglandin d2 receptor antagonists |
Also Published As
| Publication number | Publication date |
|---|---|
| PE20080186A1 (es) | 2008-04-15 |
| MA30409B1 (fr) | 2009-05-04 |
| AU2007238052A1 (en) | 2007-10-25 |
| CA2649083A1 (en) | 2007-10-25 |
| UY30283A1 (es) | 2007-11-30 |
| US20090036469A1 (en) | 2009-02-05 |
| JP2009533473A (ja) | 2009-09-17 |
| HK1131975A1 (en) | 2010-02-12 |
| RU2008144578A (ru) | 2010-05-20 |
| HN2008001530A (es) | 2012-01-17 |
| DOP2007000068A (es) | 2007-10-31 |
| ZA200807380B (en) | 2009-05-27 |
| BRPI0710710A2 (pt) | 2011-08-16 |
| AR060403A1 (es) | 2008-06-11 |
| KR20080108287A (ko) | 2008-12-12 |
| WO2007121280A1 (en) | 2007-10-25 |
| ECSP088813A (es) | 2008-11-27 |
| NO20084291L (no) | 2008-11-11 |
| CR10249A (es) | 2008-11-26 |
| MX2008011369A (es) | 2008-09-18 |
| TW200815395A (en) | 2008-04-01 |
| TNSN08339A1 (en) | 2009-12-29 |
| RU2431631C2 (ru) | 2011-10-20 |
| CN101421252B (zh) | 2011-10-12 |
| EP2010503A1 (en) | 2009-01-07 |
| CA2649083C (en) | 2011-06-28 |
| CN101421252A (zh) | 2009-04-29 |
| NZ571793A (en) | 2011-08-26 |
| UA95950C2 (en) | 2011-09-26 |
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