NZ571793A - 2,6-substituted-4-monosubstituted amino-pyrimidine as prostaglandin D2 receptor antagonists - Google Patents
2,6-substituted-4-monosubstituted amino-pyrimidine as prostaglandin D2 receptor antagonistsInfo
- Publication number
- NZ571793A NZ571793A NZ571793A NZ57179307A NZ571793A NZ 571793 A NZ571793 A NZ 571793A NZ 571793 A NZ571793 A NZ 571793A NZ 57179307 A NZ57179307 A NZ 57179307A NZ 571793 A NZ571793 A NZ 571793A
- Authority
- NZ
- New Zealand
- Prior art keywords
- phenyl
- methoxy
- pyrimidin
- ethylamino
- dichloro
- Prior art date
Links
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Classifications
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- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
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- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
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Landscapes
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US74467606P | 2006-04-12 | 2006-04-12 | |
| PCT/US2007/066481 WO2007121280A1 (en) | 2006-04-12 | 2007-04-12 | 2,6-substituted-4-monosubstituted amino-pyrimidine as prostaglandin d2 receptor antagonists |
Publications (1)
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| NZ571793A true NZ571793A (en) | 2011-08-26 |
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| NZ571793A NZ571793A (en) | 2006-04-12 | 2007-04-12 | 2,6-substituted-4-monosubstituted amino-pyrimidine as prostaglandin D2 receptor antagonists |
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| PE (1) | PE20080186A1 (enExample) |
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| JP5039594B2 (ja) * | 2008-02-08 | 2012-10-03 | 株式会社日立ハイテクノロジーズ | レビュー装置，検査領域設定支援システム、および、欠陥の画像得方法 |
| TW201034675A (en) * | 2008-12-18 | 2010-10-01 | Sanofi Aventis | Method for treating macular degeneration |
| KR20130018770A (ko) * | 2010-03-16 | 2013-02-25 | 아벤티스 파마슈티칼스 인크. | 프로스타글란딘 ｄ２ 수용체 길항제들로서의 치환된 피리미딘들 |
| WO2011115943A1 (en) * | 2010-03-16 | 2011-09-22 | Aventis Pharmaceuticals Inc. | A substituted pyrimidine as a prostaglandin d2 receptor antagonist |
| US8575158B2 (en) | 2010-07-05 | 2013-11-05 | Actelion Pharmaceuticals Ltd. | 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin D2 receptor modulators |
| EP2621276B1 (en) * | 2010-09-30 | 2017-12-27 | Merck Sharp & Dohme Corp. | 2-alkoxy pyrimidine pde10 inhibitors |
| BR112014015081A8 (pt) | 2011-12-21 | 2017-06-13 | Actelion Pharmaceuticals Ltd | derivados heterocíclicos e seu uso como moduladores do receptor d2 de prostaglandina |
| JP6127135B2 (ja) | 2012-07-05 | 2017-05-10 | アクテリオン ファーマシューティカルズ リミテッドＡｃｔｅｌｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ | １−フェニル置換ヘテロシクリル誘導体及びプロスタグランジンｄ２受容体調節剤としてのそれらの使用 |
| EP3382391A1 (en) | 2012-10-24 | 2018-10-03 | NYU Winthrop Hospital | Non-invasive biomarker to identify subjects at risk of preterm delivery |
| PL3067349T3 (pl) | 2013-11-08 | 2018-06-29 | Kissei Pharmaceutical Co., Ltd. | Pochodna karboksymetylopiperydyny |
| WO2016020288A1 (en) | 2014-08-04 | 2016-02-11 | Nuevolution A/S | Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases |
| CR20180323A (es) | 2015-11-20 | 2018-08-06 | Idorsia Pharmaceuticals Ltd | Derivados de indol n-sustituídos como moduladores de los receptores de pge2 |
| CN110621671A (zh) | 2017-05-18 | 2019-12-27 | 爱杜西亚药品有限公司 | 作为pge2受体调节剂的苯并呋喃及苯并噻吩衍生物 |
| PE20191814A1 (es) | 2017-05-18 | 2019-12-27 | Idorsia Pharmaceuticals Ltd | Derivados de pirimidina como moduladores del receptor de pge2 |
| PE20191811A1 (es) | 2017-05-18 | 2019-12-26 | Idorsia Pharmaceuticals Ltd | Derivados de pirimidina como moduladores del receptor de pge2 |
| EP3625223B1 (en) | 2017-05-18 | 2021-08-11 | Idorsia Pharmaceuticals Ltd | Pyrimidine derivatives |
| KR20200109293A (ko) | 2017-09-13 | 2020-09-22 | 프로제너티, 인크. | 자간전증 바이오마커 및 관련된 시스템 및 방법 |
| US20220408745A1 (en) * | 2019-09-13 | 2022-12-29 | Meiji Co., Ltd. | Solid food and solid milk having hole penetrating first face and second face |
| EP4070113A4 (en) | 2019-12-04 | 2023-12-20 | Biora Therapeutics, Inc. | ASSESSMENT OF PREECAMPSIA USING FREE AND DISSOCIATE PLACENTAL GROWTH FACTOR ASSAYS |
| EP4076657A1 (en) | 2019-12-20 | 2022-10-26 | Nuevolution A/S | Compounds active towards nuclear receptors |
| JOP20220160A1 (ar) | 2019-12-20 | 2023-01-30 | Nuevolution As | مركبات فعّالة نحو مستقبلات نووية |
| MX2022012260A (es) | 2020-03-31 | 2022-11-30 | Nuevolution As | Compuestos activos frente a receptores nucleares. |
| MX2022012259A (es) | 2020-03-31 | 2022-12-08 | Nuevolution As | Compuestos activos frente a receptores nucleares. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3644799A1 (de) * | 1986-06-04 | 1987-12-10 | Hoechst Ag | Neue pyrimidin-derivate, deren herstellung und verwendung |
| US5047554A (en) * | 1989-04-18 | 1991-09-10 | Pfizer Inc. | 3-substituted-2-oxindole derivatives |
| SE0200411D0 (sv) * | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
| GT200500284A (es) * | 2004-10-15 | 2006-03-27 | Aventis Pharma Inc | Pirimidinas como antagonistas del receptor de prostaglandina d2 |
| GT200600457A (es) * | 2005-10-13 | 2007-04-27 | Aventis Pharma Inc | Sal de fosfato dihidrogeno como antagonistas del receptor de prostaglandina d2 |
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2007
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- 2007-04-10 AR ARP070101501A patent/AR060403A1/es not_active Application Discontinuation
- 2007-04-12 UA UAA200813109A patent/UA95950C2/ru unknown
- 2007-04-12 EP EP07760526A patent/EP2010503A1/en not_active Withdrawn
- 2007-04-12 WO PCT/US2007/066481 patent/WO2007121280A1/en not_active Ceased
- 2007-04-12 CN CN2007800127354A patent/CN101421252B/zh not_active Expired - Fee Related
- 2007-04-12 TW TW096112790A patent/TW200815395A/zh unknown
- 2007-04-12 CA CA2649083A patent/CA2649083C/en not_active Expired - Fee Related
- 2007-04-12 RU RU2008144578/04A patent/RU2431631C2/ru not_active IP Right Cessation
- 2007-04-12 NZ NZ571793A patent/NZ571793A/en not_active IP Right Cessation
- 2007-04-12 JP JP2009505615A patent/JP2009533473A/ja not_active Abandoned
- 2007-04-12 AU AU2007238052A patent/AU2007238052B2/en not_active Expired - Fee Related
- 2007-04-12 PE PE2007000450A patent/PE20080186A1/es not_active Application Discontinuation
- 2007-04-12 MX MX2008011369A patent/MX2008011369A/es active IP Right Grant
- 2007-04-12 BR BRPI0710710-2A patent/BRPI0710710A2/pt not_active IP Right Cessation
- 2007-04-12 KR KR1020087024764A patent/KR20080108287A/ko not_active Withdrawn
- 2007-04-12 UY UY30283A patent/UY30283A1/es not_active Application Discontinuation
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2008
- 2008-08-26 CR CR10249A patent/CR10249A/es not_active Application Discontinuation
- 2008-08-27 ZA ZA200807380A patent/ZA200807380B/xx unknown
- 2008-08-27 TN TNP2008000339A patent/TNSN08339A1/en unknown
- 2008-10-07 US US12/246,918 patent/US20090036469A1/en not_active Abandoned
- 2008-10-09 EC EC2008008813A patent/ECSP088813A/es unknown
- 2008-10-10 HN HN2008001530A patent/HN2008001530A/es unknown
- 2008-10-14 NO NO20084291A patent/NO20084291L/no not_active Application Discontinuation
- 2008-11-10 MA MA31375A patent/MA30409B1/fr unknown
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|---|---|
| WO2007121280A1 (en) | 2007-10-25 |
| AU2007238052A1 (en) | 2007-10-25 |
| TW200815395A (en) | 2008-04-01 |
| UY30283A1 (es) | 2007-11-30 |
| NO20084291L (no) | 2008-11-11 |
| MX2008011369A (es) | 2008-09-18 |
| CR10249A (es) | 2008-11-26 |
| TNSN08339A1 (en) | 2009-12-29 |
| ECSP088813A (es) | 2008-11-27 |
| CN101421252B (zh) | 2011-10-12 |
| UA95950C2 (en) | 2011-09-26 |
| RU2008144578A (ru) | 2010-05-20 |
| MA30409B1 (fr) | 2009-05-04 |
| ZA200807380B (en) | 2009-05-27 |
| EP2010503A1 (en) | 2009-01-07 |
| JP2009533473A (ja) | 2009-09-17 |
| AR060403A1 (es) | 2008-06-11 |
| HN2008001530A (es) | 2012-01-17 |
| DOP2007000068A (es) | 2007-10-31 |
| CA2649083A1 (en) | 2007-10-25 |
| CA2649083C (en) | 2011-06-28 |
| US20090036469A1 (en) | 2009-02-05 |
| BRPI0710710A2 (pt) | 2011-08-16 |
| AU2007238052B2 (en) | 2011-12-22 |
| CN101421252A (zh) | 2009-04-29 |
| KR20080108287A (ko) | 2008-12-12 |
| PE20080186A1 (es) | 2008-04-15 |
| HK1131975A1 (en) | 2010-02-12 |
| RU2431631C2 (ru) | 2011-10-20 |
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| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) | ||
| LAPS | Patent lapsed |