AU2007215363A1 - Use of gallium(III) complexes for the treatment of melanomas - Google Patents
Use of gallium(III) complexes for the treatment of melanomas Download PDFInfo
- Publication number
- AU2007215363A1 AU2007215363A1 AU2007215363A AU2007215363A AU2007215363A1 AU 2007215363 A1 AU2007215363 A1 AU 2007215363A1 AU 2007215363 A AU2007215363 A AU 2007215363A AU 2007215363 A AU2007215363 A AU 2007215363A AU 2007215363 A1 AU2007215363 A1 AU 2007215363A1
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- Australia
- Prior art keywords
- compound according
- cycloalkyl
- alkyl
- aryl
- heteroaryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 201000001441 melanoma Diseases 0.000 title claims description 15
- 150000002258 gallium Chemical class 0.000 title description 15
- 150000001875 compounds Chemical class 0.000 claims description 33
- 125000003118 aryl group Chemical group 0.000 claims description 26
- 125000000217 alkyl group Chemical group 0.000 claims description 15
- 125000000753 cycloalkyl group Chemical group 0.000 claims description 14
- 125000001072 heteroaryl group Chemical group 0.000 claims description 14
- 239000003814 drug Substances 0.000 claims description 13
- 125000000623 heterocyclic group Chemical group 0.000 claims description 9
- GYHNNYVSQQEPJS-UHFFFAOYSA-N Gallium Chemical compound [Ga] GYHNNYVSQQEPJS-UHFFFAOYSA-N 0.000 claims description 8
- 229910052733 gallium Inorganic materials 0.000 claims description 7
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- 239000001257 hydrogen Substances 0.000 claims description 3
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- VXNZUUAINFGPBY-UHFFFAOYSA-N 1-Butene Chemical group CCC=C VXNZUUAINFGPBY-UHFFFAOYSA-N 0.000 description 1
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
- ASYYOZSDALANRF-UHFFFAOYSA-K 3-bis[(2-methyl-4-oxopyran-3-yl)oxy]gallanyloxy-2-methylpyran-4-one Chemical compound [Ga+3].CC=1OC=CC(=O)C=1[O-].CC=1OC=CC(=O)C=1[O-].CC=1OC=CC(=O)C=1[O-] ASYYOZSDALANRF-UHFFFAOYSA-K 0.000 description 1
- 239000005995 Aluminium silicate Substances 0.000 description 1
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- IYABWNGZIDDRAK-UHFFFAOYSA-N allene Chemical group C=C=C IYABWNGZIDDRAK-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
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- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 description 1
- 150000002259 gallium compounds Chemical class 0.000 description 1
- UPWPDUACHOATKO-UHFFFAOYSA-K gallium trichloride Chemical compound Cl[Ga](Cl)Cl UPWPDUACHOATKO-UHFFFAOYSA-K 0.000 description 1
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- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
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- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
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- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 125000001280 n-hexyl group Chemical group C(CCCCC)* 0.000 description 1
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- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Quinoline Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2013206221A AU2013206221A1 (en) | 2006-02-13 | 2013-06-07 | Use of gallium (III) complexes for the treatment of melanomas |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0022006A AT503317B1 (de) | 2006-02-13 | 2006-02-13 | Verwendung von gallium(iii)-komplexen zur herstellung eines medikaments zur behandlung von melanomen |
| ATA220/2006 | 2006-02-13 | ||
| PCT/AT2007/000071 WO2007092978A1 (de) | 2006-02-13 | 2007-02-13 | Verwendung von gallium (iii) komplexen zur behandlung von melanomen |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2013206221A Division AU2013206221A1 (en) | 2006-02-13 | 2013-06-07 | Use of gallium (III) complexes for the treatment of melanomas |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2007215363A1 true AU2007215363A1 (en) | 2007-08-23 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2007215363A Abandoned AU2007215363A1 (en) | 2006-02-13 | 2007-02-13 | Use of gallium(III) complexes for the treatment of melanomas |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7919486B2 (https=) |
| EP (1) | EP1984005B1 (https=) |
| JP (1) | JP5210888B2 (https=) |
| CN (1) | CN101466387A (https=) |
| AT (2) | AT503317B1 (https=) |
| AU (1) | AU2007215363A1 (https=) |
| CA (1) | CA2640509C (https=) |
| DE (1) | DE502007006880D1 (https=) |
| ES (1) | ES2365028T3 (https=) |
| NZ (1) | NZ571119A (https=) |
| PT (1) | PT1984005E (https=) |
| WO (1) | WO2007092978A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2533781B1 (en) | 2010-02-12 | 2016-11-16 | Niiki Pharma Inc. | Method for treating hematological cancers of myeloid origin |
| CN103108636A (zh) * | 2010-02-26 | 2013-05-15 | 尼基制药公司 | 治疗脑癌的方法 |
| WO2011133479A2 (en) | 2010-04-19 | 2011-10-27 | Niiki Pharma Inc. | Combination therapy with a proteasome inhibitor and a gallium complex |
| US20140005160A1 (en) * | 2010-12-01 | 2014-01-02 | Hooshmand SHESHBARADARAN | Method for Treating Refractory Cancer |
| CN113372269A (zh) * | 2021-06-25 | 2021-09-10 | 云南大学 | 一种席夫碱镓配合物及其制备方法和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE166056T1 (de) * | 1991-07-25 | 1998-05-15 | Philippe Collery | Gallium iii komplexe, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten |
| DE10113185A1 (de) * | 2001-03-19 | 2002-10-24 | Faustus Forschungs Cie | Zusammensetzung, enthaltend einen Gallium(III)-Komplex und einen therapeutisch wirksamen Platin-Komplex |
| DE10116527C2 (de) * | 2001-04-03 | 2003-05-15 | Faustus Forschungs Cie | Tumorhemmende Galliumverbindungen, deren Verwendung als Arzneimittel sowie ein Arzneimittel, diese enthaltend |
| AT501819B1 (de) * | 2005-04-18 | 2007-01-15 | Faustus Forschung Translationa | Verwendung von gallium(iii)-komplexen zur behandlung von tumorerkrankungen der leber |
-
2006
- 2006-02-13 AT AT0022006A patent/AT503317B1/de not_active IP Right Cessation
-
2007
- 2007-02-13 CA CA2640509A patent/CA2640509C/en not_active Expired - Fee Related
- 2007-02-13 ES ES07701315T patent/ES2365028T3/es active Active
- 2007-02-13 JP JP2008553574A patent/JP5210888B2/ja not_active Expired - Fee Related
- 2007-02-13 CN CNA2007800127458A patent/CN101466387A/zh active Pending
- 2007-02-13 WO PCT/AT2007/000071 patent/WO2007092978A1/de not_active Ceased
- 2007-02-13 AU AU2007215363A patent/AU2007215363A1/en not_active Abandoned
- 2007-02-13 AT AT07701315T patent/ATE504307T1/de active
- 2007-02-13 PT PT07701315T patent/PT1984005E/pt unknown
- 2007-02-13 NZ NZ571119A patent/NZ571119A/en not_active IP Right Cessation
- 2007-02-13 DE DE502007006880T patent/DE502007006880D1/de active Active
- 2007-02-13 EP EP07701315A patent/EP1984005B1/de active Active
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2008
- 2008-08-13 US US12/190,759 patent/US7919486B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7919486B2 (en) | 2011-04-05 |
| NZ571119A (en) | 2011-11-25 |
| DE502007006880D1 (de) | 2011-05-19 |
| ES2365028T3 (es) | 2011-09-20 |
| CA2640509C (en) | 2014-07-08 |
| WO2007092978A1 (de) | 2007-08-23 |
| AT503317B1 (de) | 2007-09-15 |
| CN101466387A (zh) | 2009-06-24 |
| JP2009525987A (ja) | 2009-07-16 |
| PT1984005E (pt) | 2011-07-11 |
| US20090137620A1 (en) | 2009-05-28 |
| JP5210888B2 (ja) | 2013-06-12 |
| CA2640509A1 (en) | 2007-08-23 |
| ATE504307T1 (de) | 2011-04-15 |
| EP1984005B1 (de) | 2011-04-06 |
| EP1984005A1 (de) | 2008-10-29 |
| AT503317A4 (de) | 2007-09-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC1 | Assignment before grant (sect. 113) |
Owner name: NIIKI PHARMA, INC. Free format text: FORMER APPLICANT(S): FAUSTUS FORSCHUNG TRANSLATIONAL DRUG DEVELOPMENT AG |
|
| MK5 | Application lapsed section 142(2)(e) - patent request and compl. specification not accepted |