AU2006299426B2 - Methods and pharmaceutical compositions for the treatment and prevention of hepatitis C infection - Google Patents
Methods and pharmaceutical compositions for the treatment and prevention of hepatitis C infection Download PDFInfo
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- AU2006299426B2 AU2006299426B2 AU2006299426A AU2006299426A AU2006299426B2 AU 2006299426 B2 AU2006299426 B2 AU 2006299426B2 AU 2006299426 A AU2006299426 A AU 2006299426A AU 2006299426 A AU2006299426 A AU 2006299426A AU 2006299426 B2 AU2006299426 B2 AU 2006299426B2
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- agent
- cyclosporin
- hcv
- solvate
- compound
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (5)
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| US72267905P | 2005-09-30 | 2005-09-30 | |
| US60/722,679 | 2005-09-30 | ||
| US78754906P | 2006-03-29 | 2006-03-29 | |
| US60/787,549 | 2006-03-29 | ||
| PCT/US2006/038823 WO2007041632A2 (en) | 2005-09-30 | 2006-10-02 | Methods and pharmaceutical compositions for the treatment and prevention of hepatitis c infection |
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| AU2006299426A1 AU2006299426A1 (en) | 2007-04-12 |
| AU2006299426B2 true AU2006299426B2 (en) | 2012-07-26 |
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| US (1) | US7754685B2 (OSRAM) |
| EP (1) | EP1933859A2 (OSRAM) |
| JP (1) | JP5517454B2 (OSRAM) |
| KR (1) | KR20080059270A (OSRAM) |
| CN (1) | CN105169369B (OSRAM) |
| AU (1) | AU2006299426B2 (OSRAM) |
| BR (1) | BRPI0616476A2 (OSRAM) |
| CA (1) | CA2623865A1 (OSRAM) |
| IL (1) | IL190478A0 (OSRAM) |
| NZ (1) | NZ567262A (OSRAM) |
| RU (1) | RU2440822C2 (OSRAM) |
| WO (1) | WO2007041632A2 (OSRAM) |
| ZA (1) | ZA200803493B (OSRAM) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CA2583494C (en) * | 2004-10-01 | 2014-01-21 | Scynexis, Inc. | 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis c infection |
| US7196161B2 (en) * | 2004-10-01 | 2007-03-27 | Scynexis Inc. | 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection |
| DE602006020152D1 (de) * | 2005-09-30 | 2011-03-31 | Scynexis Inc | Arylalkyl- und heteroarylalkyl-derivate von cyclosporin a bei der behandlung und vorbeugung einer virusinfektion |
| KR20080059270A (ko) | 2005-09-30 | 2008-06-26 | 싸이넥시스, 인크. | Ｃ형 간염 감염의 치료 및 예방을 위한 방법 및 제약조성물 |
| CN101511357B (zh) | 2006-05-19 | 2011-11-02 | 西尼克斯公司 | 环孢菌素类化合物及其组合物在制备治疗和预防眼部疾病的药物中的应用 |
| EP2027761A1 (fr) * | 2006-06-02 | 2009-02-25 | Claude Annie Perrichon | Gestion des electrons actifs |
| CA2659461A1 (en) * | 2006-08-25 | 2008-02-28 | Wyeth | Identification and characterization of hcv replicon variants with reduced susceptibility to hcv-796, and methods related thereto |
| WO2008069917A2 (en) | 2006-11-20 | 2008-06-12 | Scynexis, Inc. | Novel cyclic peptides |
| WO2008127613A1 (en) * | 2007-04-11 | 2008-10-23 | Scynexis, Inc. | New pharmaceutical compositions |
| CN101815533A (zh) | 2007-05-04 | 2010-08-25 | 弗特克斯药品有限公司 | 用于治疗hcv感染的组合治疗 |
| EP2116602A1 (en) | 2008-05-07 | 2009-11-11 | Institut Gustave Roussy | Combination products for treating cancer |
| US20090306033A1 (en) * | 2008-06-06 | 2009-12-10 | Keqiang Li | Novel cyclic peptides |
| US9090671B2 (en) * | 2008-06-06 | 2015-07-28 | Scynexis, Inc. | Macrocyclic peptides |
| KR101068160B1 (ko) * | 2008-12-30 | 2011-09-27 | 건국대학교 산학협력단 | Ｃ형 간염 바이러스 ｒｎａ핵산 중합효소의 활성을 저해하는 신규 플라보놀 유도체 |
| CA2748389A1 (en) * | 2008-12-31 | 2010-07-08 | Scynexis, Inc. | Derivatives of cyclosporin a |
| MX2011007194A (es) * | 2009-01-07 | 2013-07-12 | Scynexis Inc | Combinacion de un derivado ciclosporina y nucleosidos para tratar virus de hepatitis c (vhc). |
| US20120301463A1 (en) | 2009-09-30 | 2012-11-29 | President And Fellows Of Harvard College | Methods for Modulation of Autophagy Through the Modulation of Autophagy-Enhancing Gene Products |
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- 2006-10-02 KR KR1020087010363A patent/KR20080059270A/ko not_active Abandoned
- 2006-10-02 CA CA002623865A patent/CA2623865A1/en not_active Abandoned
- 2006-10-02 JP JP2008533792A patent/JP5517454B2/ja not_active Expired - Fee Related
- 2006-10-02 RU RU2008117157/15A patent/RU2440822C2/ru not_active IP Right Cessation
- 2006-10-02 WO PCT/US2006/038823 patent/WO2007041632A2/en not_active Ceased
- 2006-10-02 NZ NZ567262A patent/NZ567262A/en not_active IP Right Cessation
- 2006-10-02 AU AU2006299426A patent/AU2006299426B2/en not_active Ceased
- 2006-10-02 CN CN201510211763.5A patent/CN105169369B/zh active Active
- 2006-10-02 US US11/542,930 patent/US7754685B2/en not_active Expired - Fee Related
- 2006-10-02 BR BRPI0616476-5A patent/BRPI0616476A2/pt not_active IP Right Cessation
- 2006-10-02 EP EP06816231A patent/EP1933859A2/en not_active Withdrawn
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2008
- 2008-03-27 IL IL190478A patent/IL190478A0/en not_active IP Right Cessation
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Also Published As
| Publication number | Publication date |
|---|---|
| US7754685B2 (en) | 2010-07-13 |
| ZA200803493B (en) | 2009-12-30 |
| NZ567262A (en) | 2011-12-22 |
| IL190478A0 (en) | 2008-11-03 |
| CA2623865A1 (en) | 2007-04-12 |
| EP1933859A2 (en) | 2008-06-25 |
| AU2006299426A1 (en) | 2007-04-12 |
| CN105169369A (zh) | 2015-12-23 |
| CN105169369B (zh) | 2019-10-18 |
| JP2009510129A (ja) | 2009-03-12 |
| RU2440822C2 (ru) | 2012-01-27 |
| RU2008117157A (ru) | 2009-11-10 |
| BRPI0616476A2 (pt) | 2011-06-21 |
| WO2007041632A2 (en) | 2007-04-12 |
| WO2007041632A3 (en) | 2007-12-13 |
| JP5517454B2 (ja) | 2014-06-11 |
| US20070173440A1 (en) | 2007-07-26 |
| KR20080059270A (ko) | 2008-06-26 |
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