AU2006271308B2 - Inhibition of the tumorigenic potential of tumor stem cells by LIF and BMPS - Google Patents

Inhibition of the tumorigenic potential of tumor stem cells by LIF and BMPS Download PDF

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Publication number
AU2006271308B2
AU2006271308B2 AU2006271308A AU2006271308A AU2006271308B2 AU 2006271308 B2 AU2006271308 B2 AU 2006271308B2 AU 2006271308 A AU2006271308 A AU 2006271308A AU 2006271308 A AU2006271308 A AU 2006271308A AU 2006271308 B2 AU2006271308 B2 AU 2006271308B2
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Australia
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bmp
tumor
cells
cell
preparation
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AU2006271308A
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AU2006271308A1 (en
Inventor
Brent Allan Reynolds
Angelo Luigi Vescovi
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STEMGEN SpA
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STEMGEN SpA
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Priority to AU2012202157A priority Critical patent/AU2012202157B2/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2093—Leukaemia inhibitory factor [LIF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AU2006271308A 2005-07-19 2006-07-19 Inhibition of the tumorigenic potential of tumor stem cells by LIF and BMPS Active AU2006271308B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2012202157A AU2012202157B2 (en) 2005-07-19 2012-04-13 Inhibition of the tumorigenic potential of tumor stem cells by LIF and BMPS

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70085905P 2005-07-19 2005-07-19
US60/700,859 2005-07-19
PCT/IB2006/002296 WO2007010394A2 (en) 2005-07-19 2006-07-19 Inhibition of the tumorigenic potential of tumor stem cells by lif and bmps

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2012202157A Division AU2012202157B2 (en) 2005-07-19 2012-04-13 Inhibition of the tumorigenic potential of tumor stem cells by LIF and BMPS

Publications (2)

Publication Number Publication Date
AU2006271308A1 AU2006271308A1 (en) 2007-01-25
AU2006271308B2 true AU2006271308B2 (en) 2012-12-20

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006271308A Active AU2006271308B2 (en) 2005-07-19 2006-07-19 Inhibition of the tumorigenic potential of tumor stem cells by LIF and BMPS

Country Status (13)

Country Link
US (2) US9220756B2 (enExample)
EP (2) EP1904093B1 (enExample)
JP (3) JP5189977B2 (enExample)
KR (2) KR101311061B1 (enExample)
AU (1) AU2006271308B2 (enExample)
CA (2) CA2615491C (enExample)
DK (2) DK1904093T3 (enExample)
ES (2) ES2710601T3 (enExample)
HR (1) HRP20181379T1 (enExample)
HU (2) HUE042197T2 (enExample)
NZ (2) NZ565172A (enExample)
PL (2) PL1904093T3 (enExample)
WO (1) WO2007010394A2 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE042197T2 (hu) 2005-07-19 2019-06-28 Stemgen S P A Tumor õssejtek tumorképzõ potenciáljának gátlása LIF segítségével
ATE526984T1 (de) * 2008-02-13 2011-10-15 Dkfz Krebsforschungszentrum Knochen-morphogenetische proteine zur verwendung zur behandlung und prävention von neuroblastomen
KR20180043317A (ko) 2015-08-25 2018-04-27 히스티드 아게 조직 형성 유도용 화합물 및 그것의 용도
JP6890836B2 (ja) * 2015-09-17 2021-06-18 ヒスタイド アクツィエンゲゼルシャフト 腫瘍細胞を非腫瘍細胞に変換するための医薬的連合体及びその使用
SI3349776T1 (sl) * 2015-09-17 2021-04-30 Histide Ag Farmacevtska asociacija agonista receptorja rastnega faktorja in zaviralca adhezijskega proteina za pretvorbo neoplastične celice v ne-neoplastično celico in njena uporaba
WO2017046215A2 (en) * 2015-09-17 2017-03-23 Histide Ag Pharmaceutical association for converting a neoplastic cell into a non-neoplastic cell and uses thereof
SI3349778T1 (sl) * 2015-09-17 2021-12-31 Histide Ag Farmacevtska asociacija agonista receptorja rastnega faktorja in zaviralca adhezijskega proteina za pretvorbo neoplastične celice v ne-neoplastično celico in njena uporaba
WO2017046226A2 (en) * 2015-09-17 2017-03-23 Histide Ag Pharmaceutical association for converting a neoplastic cell into a non-neoplastic cell and uses thereof.
US20220105122A1 (en) * 2018-12-28 2022-04-07 The University Of Tokyo Therapeutic and prophylactic agent for glioma, brain tumor malignancy marker, brain tumor prognostic marker, method for determining malignancy and prognosis of brain tumor and antibody inhibiting tumor proliferation

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US5010175A (en) 1988-05-02 1991-04-23 The Regents Of The University Of California General method for producing and selecting peptides with specific properties
US5328470A (en) 1989-03-31 1994-07-12 The Regents Of The University Of Michigan Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor
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Also Published As

Publication number Publication date
WO2007010394A3 (en) 2007-08-30
EP1904093A2 (en) 2008-04-02
ES2686093T3 (es) 2018-10-16
HUE040063T2 (hu) 2019-02-28
WO2007010394A2 (en) 2007-01-25
CA2615491A1 (en) 2007-01-25
PL3117833T3 (pl) 2019-06-28
NZ598031A (en) 2013-11-29
CA2615491C (en) 2016-11-29
HRP20181379T1 (hr) 2018-11-16
DK3117833T3 (en) 2019-03-18
NZ565172A (en) 2012-12-21
KR20080082595A (ko) 2008-09-11
CA2790675C (en) 2016-12-20
AU2006271308A1 (en) 2007-01-25
HUE042197T2 (hu) 2019-06-28
JP5891068B2 (ja) 2016-03-22
KR101338533B1 (ko) 2013-12-12
KR20120125990A (ko) 2012-11-19
ES2710601T3 (es) 2019-04-26
US9220756B2 (en) 2015-12-29
US20160228511A1 (en) 2016-08-11
KR101311061B1 (ko) 2013-09-25
US9737589B2 (en) 2017-08-22
JP2009502771A (ja) 2009-01-29
DK1904093T3 (en) 2018-09-03
US20100167999A1 (en) 2010-07-01
EP1904093B1 (en) 2018-06-13
EP3117833A1 (en) 2017-01-18
EP3117833B1 (en) 2019-01-23
CA2790675A1 (en) 2007-01-25
JP2015057452A (ja) 2015-03-26
JP5189977B2 (ja) 2013-04-24
JP2012107063A (ja) 2012-06-07
PL1904093T3 (pl) 2018-12-31

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