HRP20181379T1 - Inhibiranje tumorogenog potencijala tumorskih matičnih stanica s bmp-4 - Google Patents

Inhibiranje tumorogenog potencijala tumorskih matičnih stanica s bmp-4

Info

Publication number
HRP20181379T1
HRP20181379T1 HRP20181379TT HRP20181379T HRP20181379T1 HR P20181379 T1 HRP20181379 T1 HR P20181379T1 HR P20181379T T HRP20181379T T HR P20181379TT HR P20181379 T HRP20181379 T HR P20181379T HR P20181379 T1 HRP20181379 T1 HR P20181379T1
Authority
HR
Croatia
Prior art keywords
bmp
inhibition
stem cells
tumor stem
tumorigenic potential
Prior art date
Application number
HRP20181379TT
Other languages
English (en)
Inventor
Angelo Luigi Vescovi
Brent Allan Reynolds
Original Assignee
Stemgen S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stemgen S.P.A. filed Critical Stemgen S.P.A.
Publication of HRP20181379T1 publication Critical patent/HRP20181379T1/hr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2093—Leukaemia inhibitory factor [LIF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
HRP20181379TT 2005-07-19 2018-08-28 Inhibiranje tumorogenog potencijala tumorskih matičnih stanica s bmp-4 HRP20181379T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70085905P 2005-07-19 2005-07-19
PCT/IB2006/002296 WO2007010394A2 (en) 2005-07-19 2006-07-19 Inhibition of the tumorigenic potential of tumor stem cells by lif and bmps
EP06795317.4A EP1904093B1 (en) 2005-07-19 2006-07-19 Inhibition of the tumorigenic potential of tumor stem cells by bmp-4

Publications (1)

Publication Number Publication Date
HRP20181379T1 true HRP20181379T1 (hr) 2018-11-16

Family

ID=37420973

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20181379TT HRP20181379T1 (hr) 2005-07-19 2018-08-28 Inhibiranje tumorogenog potencijala tumorskih matičnih stanica s bmp-4

Country Status (13)

Country Link
US (2) US9220756B2 (hr)
EP (2) EP1904093B1 (hr)
JP (3) JP5189977B2 (hr)
KR (2) KR101311061B1 (hr)
AU (1) AU2006271308B2 (hr)
CA (2) CA2615491C (hr)
DK (2) DK1904093T3 (hr)
ES (2) ES2710601T3 (hr)
HR (1) HRP20181379T1 (hr)
HU (2) HUE040063T2 (hr)
NZ (2) NZ598031A (hr)
PL (2) PL1904093T3 (hr)
WO (1) WO2007010394A2 (hr)

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HUE040063T2 (hu) 2005-07-19 2019-02-28 Stemgen S P A Tumor õssejtek tumorképzõ potenciáljának gátlása BMP-4 segítségével
EP2259792B1 (en) 2008-02-13 2011-10-05 DKFZ Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts Bone morphogenetic proteins for use in treating and preventing neuroblastomas
AU2016311298A1 (en) 2015-08-25 2018-02-08 Histide Ag Compounds for inducing tissue formation and uses thereof
WO2017046226A2 (en) * 2015-09-17 2017-03-23 Histide Ag Pharmaceutical association for converting a neoplastic cell into a non-neoplastic cell and uses thereof.
JP7145503B2 (ja) * 2015-09-17 2022-10-03 ヒスタイド アクツィエンゲゼルシャフト 腫瘍細胞を非腫瘍細胞に変換するための医薬的連合体及びその使用
EP3349782A2 (en) * 2015-09-17 2018-07-25 Histide AG Pharmaceutical association comprising a growth factor receptor agonist conjugated to a bioactive carrier for converting a neoplastic cell into a non-neoplastic cell and uses thereof
EP3875102A1 (en) * 2015-09-17 2021-09-08 Histide AG Pharmaceutical association of growth factor receptor agonist and adhesion protein inhibitor for converting a neoplastic cell into a non-neoplastic cell and uses thereof
JP6890836B2 (ja) * 2015-09-17 2021-06-18 ヒスタイド アクツィエンゲゼルシャフト 腫瘍細胞を非腫瘍細胞に変換するための医薬的連合体及びその使用
CN113597315A (zh) * 2018-12-28 2021-11-02 国立大学法人东京大学 用于治疗和预防神经胶质瘤的药剂、脑肿瘤恶性程度标志物、脑肿瘤预后标志物、确定脑肿瘤恶性程度和预后的方法以及抑制肿瘤增殖的抗体

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Also Published As

Publication number Publication date
AU2006271308A1 (en) 2007-01-25
EP1904093A2 (en) 2008-04-02
KR20080082595A (ko) 2008-09-11
KR101338533B1 (ko) 2013-12-12
AU2006271308B2 (en) 2012-12-20
EP1904093B1 (en) 2018-06-13
JP5891068B2 (ja) 2016-03-22
US20100167999A1 (en) 2010-07-01
CA2615491A1 (en) 2007-01-25
WO2007010394A2 (en) 2007-01-25
DK3117833T3 (en) 2019-03-18
CA2615491C (en) 2016-11-29
JP2015057452A (ja) 2015-03-26
EP3117833A1 (en) 2017-01-18
CA2790675C (en) 2016-12-20
JP2012107063A (ja) 2012-06-07
JP2009502771A (ja) 2009-01-29
KR101311061B1 (ko) 2013-09-25
ES2686093T3 (es) 2018-10-16
NZ598031A (en) 2013-11-29
JP5189977B2 (ja) 2013-04-24
DK1904093T3 (en) 2018-09-03
PL3117833T3 (pl) 2019-06-28
US20160228511A1 (en) 2016-08-11
HUE042197T2 (hu) 2019-06-28
HUE040063T2 (hu) 2019-02-28
KR20120125990A (ko) 2012-11-19
CA2790675A1 (en) 2007-01-25
ES2710601T3 (es) 2019-04-26
WO2007010394A3 (en) 2007-08-30
US9737589B2 (en) 2017-08-22
NZ565172A (en) 2012-12-21
PL1904093T3 (pl) 2018-12-31
US9220756B2 (en) 2015-12-29
EP3117833B1 (en) 2019-01-23

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