NZ565172A - Inhibition of the tumorigenic potential of tumor stem cells by LIF and BMPS - Google Patents

Inhibition of the tumorigenic potential of tumor stem cells by LIF and BMPS

Info

Publication number
NZ565172A
NZ565172A NZ565172A NZ56517206A NZ565172A NZ 565172 A NZ565172 A NZ 565172A NZ 565172 A NZ565172 A NZ 565172A NZ 56517206 A NZ56517206 A NZ 56517206A NZ 565172 A NZ565172 A NZ 565172A
Authority
NZ
New Zealand
Prior art keywords
targeted
targeted tumor
tumor stem
cell
tumor
Prior art date
Application number
NZ565172A
Other languages
English (en)
Inventor
Angelo Luigi Vescovi
Brent Allan Reynolds
Original Assignee
Stemgen S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stemgen S P A filed Critical Stemgen S P A
Priority to NZ598031A priority Critical patent/NZ598031A/xx
Publication of NZ565172A publication Critical patent/NZ565172A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2093—Leukaemia inhibitory factor [LIF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
NZ565172A 2005-07-19 2006-07-19 Inhibition of the tumorigenic potential of tumor stem cells by LIF and BMPS NZ565172A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NZ598031A NZ598031A (en) 2005-07-19 2006-07-19 Inhibition of the tumorigenic potential of tumor stem cells by lif and bmps

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70085905P 2005-07-19 2005-07-19
PCT/IB2006/002296 WO2007010394A2 (en) 2005-07-19 2006-07-19 Inhibition of the tumorigenic potential of tumor stem cells by lif and bmps

Publications (1)

Publication Number Publication Date
NZ565172A true NZ565172A (en) 2012-12-21

Family

ID=37420973

Family Applications (2)

Application Number Title Priority Date Filing Date
NZ565172A NZ565172A (en) 2005-07-19 2006-07-19 Inhibition of the tumorigenic potential of tumor stem cells by LIF and BMPS
NZ598031A NZ598031A (en) 2005-07-19 2006-07-19 Inhibition of the tumorigenic potential of tumor stem cells by lif and bmps

Family Applications After (1)

Application Number Title Priority Date Filing Date
NZ598031A NZ598031A (en) 2005-07-19 2006-07-19 Inhibition of the tumorigenic potential of tumor stem cells by lif and bmps

Country Status (13)

Country Link
US (2) US9220756B2 (enExample)
EP (2) EP1904093B1 (enExample)
JP (3) JP5189977B2 (enExample)
KR (2) KR101311061B1 (enExample)
AU (1) AU2006271308B2 (enExample)
CA (2) CA2615491C (enExample)
DK (2) DK1904093T3 (enExample)
ES (2) ES2710601T3 (enExample)
HR (1) HRP20181379T1 (enExample)
HU (2) HUE042197T2 (enExample)
NZ (2) NZ565172A (enExample)
PL (2) PL1904093T3 (enExample)
WO (1) WO2007010394A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE042197T2 (hu) 2005-07-19 2019-06-28 Stemgen S P A Tumor õssejtek tumorképzõ potenciáljának gátlása LIF segítségével
ATE526984T1 (de) * 2008-02-13 2011-10-15 Dkfz Krebsforschungszentrum Knochen-morphogenetische proteine zur verwendung zur behandlung und prävention von neuroblastomen
KR20180043317A (ko) 2015-08-25 2018-04-27 히스티드 아게 조직 형성 유도용 화합물 및 그것의 용도
JP6890836B2 (ja) * 2015-09-17 2021-06-18 ヒスタイド アクツィエンゲゼルシャフト 腫瘍細胞を非腫瘍細胞に変換するための医薬的連合体及びその使用
SI3349776T1 (sl) * 2015-09-17 2021-04-30 Histide Ag Farmacevtska asociacija agonista receptorja rastnega faktorja in zaviralca adhezijskega proteina za pretvorbo neoplastične celice v ne-neoplastično celico in njena uporaba
WO2017046215A2 (en) * 2015-09-17 2017-03-23 Histide Ag Pharmaceutical association for converting a neoplastic cell into a non-neoplastic cell and uses thereof
SI3349778T1 (sl) * 2015-09-17 2021-12-31 Histide Ag Farmacevtska asociacija agonista receptorja rastnega faktorja in zaviralca adhezijskega proteina za pretvorbo neoplastične celice v ne-neoplastično celico in njena uporaba
WO2017046226A2 (en) * 2015-09-17 2017-03-23 Histide Ag Pharmaceutical association for converting a neoplastic cell into a non-neoplastic cell and uses thereof.
US20220105122A1 (en) * 2018-12-28 2022-04-07 The University Of Tokyo Therapeutic and prophylactic agent for glioma, brain tumor malignancy marker, brain tumor prognostic marker, method for determining malignancy and prognosis of brain tumor and antibody inhibiting tumor proliferation

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US5328470A (en) 1989-03-31 1994-07-12 The Regents Of The University Of Michigan Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor
US5324519A (en) * 1989-07-24 1994-06-28 Atrix Laboratories, Inc. Biodegradable polymer composition
GB9004890D0 (en) * 1990-03-05 1990-05-02 Heath John K Leukaemia inhibitory factor
IE66205B1 (en) 1990-06-14 1995-12-13 Paul A Bartlett Polypeptide analogs
US5650489A (en) 1990-07-02 1997-07-22 The Arizona Board Of Regents Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
DE69231726D1 (de) * 1991-12-24 2001-04-12 Amrad Corp Ltd Verwendung von leukämieinhibierendem faktor (lif) zur behandlung von tumoren und sarkomen
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EP0756628B1 (en) * 1994-04-29 2007-11-14 Curis, Inc. Morphogenic protein-specific cell surface receptors and uses therefor
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US6281015B1 (en) * 1994-12-16 2001-08-28 Children's Medical Center Corp. Localized delivery of factors enhancing survival of transplanted cells
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JP2005098727A (ja) 2003-09-22 2005-04-14 Hosiden Corp 振動センサ
JP4970948B2 (ja) 2003-12-05 2012-07-11 ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティ 癌幹細胞の同定、単離、および除去の方法
EP2789342A1 (en) * 2004-06-17 2014-10-15 Thrasos Innovation, Inc. TDF-related compounds and analogs thereof
HUE042197T2 (hu) * 2005-07-19 2019-06-28 Stemgen S P A Tumor õssejtek tumorképzõ potenciáljának gátlása LIF segítségével
ES2363358B1 (es) * 2009-04-03 2012-06-21 FUNDACIÓ INSTITUT DE RECERCA HOSPITAL UNIVERSITARI VALL D'HEBRON (Titular al Agentes terapéuticos para el tratamiento de enfermedades asociadas con una proliferación celular indeseable.
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Also Published As

Publication number Publication date
WO2007010394A3 (en) 2007-08-30
EP1904093A2 (en) 2008-04-02
ES2686093T3 (es) 2018-10-16
HUE040063T2 (hu) 2019-02-28
WO2007010394A2 (en) 2007-01-25
CA2615491A1 (en) 2007-01-25
PL3117833T3 (pl) 2019-06-28
NZ598031A (en) 2013-11-29
CA2615491C (en) 2016-11-29
HRP20181379T1 (hr) 2018-11-16
DK3117833T3 (en) 2019-03-18
KR20080082595A (ko) 2008-09-11
CA2790675C (en) 2016-12-20
AU2006271308A1 (en) 2007-01-25
HUE042197T2 (hu) 2019-06-28
JP5891068B2 (ja) 2016-03-22
KR101338533B1 (ko) 2013-12-12
KR20120125990A (ko) 2012-11-19
ES2710601T3 (es) 2019-04-26
US9220756B2 (en) 2015-12-29
US20160228511A1 (en) 2016-08-11
KR101311061B1 (ko) 2013-09-25
US9737589B2 (en) 2017-08-22
JP2009502771A (ja) 2009-01-29
DK1904093T3 (en) 2018-09-03
US20100167999A1 (en) 2010-07-01
EP1904093B1 (en) 2018-06-13
EP3117833A1 (en) 2017-01-18
AU2006271308B2 (en) 2012-12-20
EP3117833B1 (en) 2019-01-23
CA2790675A1 (en) 2007-01-25
JP2015057452A (ja) 2015-03-26
JP5189977B2 (ja) 2013-04-24
JP2012107063A (ja) 2012-06-07
PL1904093T3 (pl) 2018-12-31

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