AU2006258079A1 - Resolution of enantiomeric mixtures of beta-lactams - Google Patents

Resolution of enantiomeric mixtures of beta-lactams Download PDF

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Publication number
AU2006258079A1
AU2006258079A1 AU2006258079A AU2006258079A AU2006258079A1 AU 2006258079 A1 AU2006258079 A1 AU 2006258079A1 AU 2006258079 A AU2006258079 A AU 2006258079A AU 2006258079 A AU2006258079 A AU 2006258079A AU 2006258079 A1 AU2006258079 A1 AU 2006258079A1
Authority
AU
Australia
Prior art keywords
cis
heterocyclo
proline
substituted
lactam
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2006258079A
Other languages
English (en)
Inventor
Robert A. Holton
Phong Vu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Florida State University Research Foundation Inc
Original Assignee
Florida State University Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Florida State University Research Foundation Inc filed Critical Florida State University Research Foundation Inc
Publication of AU2006258079A1 publication Critical patent/AU2006258079A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2006258079A 2005-06-10 2006-06-08 Resolution of enantiomeric mixtures of beta-lactams Abandoned AU2006258079A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US68942505P 2005-06-10 2005-06-10
US60/689,425 2005-06-10
US70893105P 2005-08-17 2005-08-17
US60/708,931 2005-08-17
PCT/US2006/022266 WO2006135669A2 (en) 2005-06-10 2006-06-08 RESOLUTION OF ENANTIOMERIC MIXTURES OF β-LACTAMS

Publications (1)

Publication Number Publication Date
AU2006258079A1 true AU2006258079A1 (en) 2006-12-21

Family

ID=37532803

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006258079A Abandoned AU2006258079A1 (en) 2005-06-10 2006-06-08 Resolution of enantiomeric mixtures of beta-lactams

Country Status (11)

Country Link
US (1) US20060281918A1 (pt)
EP (1) EP1888521A2 (pt)
JP (1) JP2008546646A (pt)
KR (1) KR20080033250A (pt)
AU (1) AU2006258079A1 (pt)
BR (1) BRPI0611959A2 (pt)
CA (1) CA2610411A1 (pt)
IL (1) IL187857A0 (pt)
MX (1) MX2007015594A (pt)
TW (1) TW200738664A (pt)
WO (1) WO2006135669A2 (pt)

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3972925A (en) * 1974-10-29 1976-08-03 Eli Lilly And Company N-perfluoroacyl-amino acids and derivatives thereof
US4719207A (en) * 1984-06-25 1988-01-12 Yamanouchi Pharmaceutical Co., Ltd. CNS active substituted azetidinone compounds
SG45180A1 (en) * 1987-02-17 1998-01-16 Ciba Geigy Ag A process for the manufacture of 4-acetoxy-3- hydroxy-ethyl-azetidinone
DE4111913A1 (de) * 1991-04-12 1992-10-15 Degussa Verfahren zur herstellung von l-carnitin aus d,l-carnitinnitrilsalzen
US5284864A (en) * 1991-09-23 1994-02-08 Florida State University Butenyl substituted taxanes and pharmaceutical compositions containing them
US5294737A (en) * 1992-02-27 1994-03-15 The Research Foundation State University Of New York Process for the production of chiral hydroxy-β-lactams and hydroxyamino acids derived therefrom
JP3181671B2 (ja) * 1992-03-13 2001-07-03 杏林製薬株式会社 新規光学分割剤ｎ−シンナモイルプロリン誘導体及びそのアルカリ塩
EP1228759B1 (en) * 1993-03-22 2004-12-15 Florida State University Pharmaceutical compositions containing a taxane having a furyl or thienyl substituted side-chain
JP3274247B2 (ja) * 1993-09-20 2002-04-15 杏林製薬株式会社 光学活性なインドリン誘導体の製法と中間体
EP0933360A1 (en) * 1997-12-22 1999-08-04 Pharmachemie B.V. Synthesis of new beta-lactams
US6548293B1 (en) * 1999-10-18 2003-04-15 Fsu Research Foundation, Inc. Enzymatic process for the resolution of enantiomeric mixtures of β-lactams
BRPI0611771A2 (pt) * 2005-06-10 2011-12-20 Univ Florida State Res Found processos para a preparação de paclitaxel
EP1919926A2 (en) * 2005-06-10 2008-05-14 Florida State University Research Foundation, Inc. Processes for the production of polycyclic fused ring compounds

Also Published As

Publication number Publication date
WO2006135669A2 (en) 2006-12-21
CA2610411A1 (en) 2006-12-21
EP1888521A2 (en) 2008-02-20
TW200738664A (en) 2007-10-16
IL187857A0 (en) 2008-03-20
US20060281918A1 (en) 2006-12-14
BRPI0611959A2 (pt) 2011-12-20
KR20080033250A (ko) 2008-04-16
MX2007015594A (es) 2008-03-07
JP2008546646A (ja) 2008-12-25
WO2006135669A3 (en) 2007-04-19

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Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period