AU2006251167A1

AU2006251167A1 - Tetrahydropyridothiophenes for use in the treatment of cancer

Tetrahydropyridothiophenes for use in the treatment of cancer Download PDF

Info

Publication number: AU2006251167A1
Authority: AU; Australia
Prior art keywords: pyridin; cyano; phenyl; thieno; tetrahydro
Prior art date: 2005-05-25
Legal status : Abandoned

Application number

AU2006251167A

Other languages

English (en)

Other versions

AU2006251167A8 (en

Inventor

Thomas Baer

Thomas Beckers

Petra Gimmnich

Klaus Pekari

Mathias Schmidt

Current Assignee

4SC AG

Original Assignee

Altana Pharma AG

Priority date

2005-05-25

Filing date

2006-05-24

Publication date

2006-11-30

2006-05-24 Application filed by Altana Pharma AG filed Critical Altana Pharma AG

2006-11-30 Publication of AU2006251167A1 publication Critical patent/AU2006251167A1/en

2008-04-03 Publication of AU2006251167A8 publication Critical patent/AU2006251167A8/en

2008-10-02 Assigned to 4SC AG reassignment 4SC AG Request for Assignment Assignors: NYCOMED GMBH

Status Abandoned legal-status Critical Current

Links

206010028980 Neoplasm Diseases 0.000 title claims description 91
201000011510 cancer Diseases 0.000 title claims description 47
238000011282 treatment Methods 0.000 title claims description 22
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150000001875 compounds Chemical class 0.000 claims description 494
-1 1-4C-alkoxycarbonyl Chemical group 0.000 claims description 337
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ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims description 108
239000000460 chlorine Substances 0.000 claims description 108
125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 claims description 80
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 79
150000003839 salts Chemical class 0.000 claims description 77
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208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 70
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PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims description 68
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