AU2006218404A1 - N-phenyl benzamide derivatives as sirtuin modulators - Google Patents

N-phenyl benzamide derivatives as sirtuin modulators Download PDF

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Publication number
AU2006218404A1
AU2006218404A1 AU2006218404A AU2006218404A AU2006218404A1 AU 2006218404 A1 AU2006218404 A1 AU 2006218404A1 AU 2006218404 A AU2006218404 A AU 2006218404A AU 2006218404 A AU2006218404 A AU 2006218404A AU 2006218404 A1 AU2006218404 A1 AU 2006218404A1
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AU
Australia
Prior art keywords
subject
compound
ring
sirtuin
substituted
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Abandoned
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AU2006218404A
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English (en)
Inventor
Jean Bemis
Michael Milburn
Jill Milne
Karl D. Normington
Joseph J. Nunes
Chi B. Vu
Roger Xie
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Sirtris Pharmaceuticals Inc
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Sirtris Pharmaceuticals Inc
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Publication of AU2006218404A1 publication Critical patent/AU2006218404A1/en
Abandoned legal-status Critical Current

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C07D277/66—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
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    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
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    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
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    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/42—Benzopyrazines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
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    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
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    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/20—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
    • C07D265/22—Oxygen atoms
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

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  • Urology & Nephrology (AREA)
  • Psychology (AREA)
  • Reproductive Health (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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AU2006218404A 2005-03-03 2006-03-03 N-phenyl benzamide derivatives as sirtuin modulators Abandoned AU2006218404A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US65851605P 2005-03-03 2005-03-03
US60/658,516 2005-03-03
US70561205P 2005-08-04 2005-08-04
US60/705,612 2005-08-04
US74178305P 2005-12-02 2005-12-02
US60/741,783 2005-12-02
PCT/US2006/007745 WO2006094236A1 (en) 2005-03-03 2006-03-03 N-phenyl benzamide derivatives as sirtuin modulators

Publications (1)

Publication Number Publication Date
AU2006218404A1 true AU2006218404A1 (en) 2006-09-08

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ID=36499236

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AU2006218404A Abandoned AU2006218404A1 (en) 2005-03-03 2006-03-03 N-phenyl benzamide derivatives as sirtuin modulators

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US (1) US20090163476A1 (enExample)
EP (1) EP1853610A1 (enExample)
JP (1) JP2008535790A (enExample)
AU (1) AU2006218404A1 (enExample)
CA (1) CA2599989A1 (enExample)
WO (1) WO2006094236A1 (enExample)

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