AU2006214166B2 - Transmucosal administration of drug compositions for treating and preventing disorders in animals - Google Patents

Transmucosal administration of drug compositions for treating and preventing disorders in animals Download PDF

Info

Publication number
AU2006214166B2
AU2006214166B2 AU2006214166A AU2006214166A AU2006214166B2 AU 2006214166 B2 AU2006214166 B2 AU 2006214166B2 AU 2006214166 A AU2006214166 A AU 2006214166A AU 2006214166 A AU2006214166 A AU 2006214166A AU 2006214166 B2 AU2006214166 B2 AU 2006214166B2
Authority
AU
Australia
Prior art keywords
administration
agent
oral
transmucosal
active agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2006214166A
Other languages
English (en)
Other versions
AU2006214166A1 (en
Inventor
Antonio Benitz
Mark Heit
David Petrick
Dennis Steadman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zoetis Belgium SA
Original Assignee
Zoetis Belgium SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zoetis Belgium SA filed Critical Zoetis Belgium SA
Publication of AU2006214166A1 publication Critical patent/AU2006214166A1/en
Application granted granted Critical
Publication of AU2006214166B2 publication Critical patent/AU2006214166B2/en
Priority to AU2012200031A priority Critical patent/AU2012200031B9/en
Assigned to NOVADEL PHARMA, INC., ABBOTT LABORATORIES reassignment NOVADEL PHARMA, INC. Request for Assignment Assignors: NOVADEL PHARMA, INC., VELCERA PHARMACEUTICALS, INC
Assigned to ABBOTT LABORATORIES reassignment ABBOTT LABORATORIES Request for Assignment Assignors: ABBOTT LABORATORIES, NOVADEL PHARMA, INC.
Assigned to ZOETIS BELGIUM S.A. reassignment ZOETIS BELGIUM S.A. Request for Assignment Assignors: ABBOTT LABORATORIES
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006—Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2250/00—Specially adapted for animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Physiology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Anesthesiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Wood Science & Technology (AREA)
  • Mechanical Engineering (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
AU2006214166A 2005-02-17 2006-02-17 Transmucosal administration of drug compositions for treating and preventing disorders in animals Ceased AU2006214166B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2012200031A AU2012200031B9 (en) 2005-02-17 2012-01-03 Transmucosal administration of drug compositions for treating and preventing disorders in animals

Applications Claiming Priority (21)

Application Number Priority Date Filing Date Title
US65396405P 2005-02-17 2005-02-17
US60/653,964 2005-02-17
US66192005P 2005-03-16 2005-03-16
US60/661,920 2005-03-16
US66418105P 2005-03-23 2005-03-23
US66418305P 2005-03-23 2005-03-23
US60/664,181 2005-03-23
US60/664,183 2005-03-23
US66493905P 2005-03-25 2005-03-25
US66493805P 2005-03-25 2005-03-25
US60/664,939 2005-03-25
US60/664,938 2005-03-25
US66552505P 2005-03-28 2005-03-28
US60/665,525 2005-03-28
US66988805P 2005-04-11 2005-04-11
US60/669,888 2005-04-11
US67065105P 2005-04-13 2005-04-13
US60/670,651 2005-04-13
US69394205P 2005-06-27 2005-06-27
US60/693,942 2005-06-27
PCT/US2006/005575 WO2006089082A2 (en) 2005-02-17 2006-02-17 Transmucosal administration of drug compositions for treating and preventing disorders in animals

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2012200031A Division AU2012200031B9 (en) 2005-02-17 2012-01-03 Transmucosal administration of drug compositions for treating and preventing disorders in animals

Publications (2)

Publication Number Publication Date
AU2006214166A1 AU2006214166A1 (en) 2006-08-24
AU2006214166B2 true AU2006214166B2 (en) 2011-09-29

Family

ID=36917071

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006214166A Ceased AU2006214166B2 (en) 2005-02-17 2006-02-17 Transmucosal administration of drug compositions for treating and preventing disorders in animals

Country Status (7)

Country Link
US (3) US8097614B2 (https=)
EP (2) EP2767163A1 (https=)
JP (2) JP5577021B2 (https=)
AU (1) AU2006214166B2 (https=)
CA (1) CA2597956C (https=)
ES (1) ES2490595T3 (https=)
WO (1) WO2006089082A2 (https=)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040136914A1 (en) 1997-10-01 2004-07-15 Dugger Harry A. Buccal, polar and non-polar spray containing ondansetron
US7632517B2 (en) 1997-10-01 2009-12-15 Novadel Pharma Inc. Buccal, polar and non-polar spray containing zolpidem
US20060205681A1 (en) * 2002-06-21 2006-09-14 Maryam Moaddeb Homogenous paste formulations
US8821915B2 (en) 2002-08-09 2014-09-02 Veroscience, Llc Therapeutic process for the treatment of the metabolic syndrome and associated metabolic disorders
ES2490595T3 (es) 2005-02-17 2014-09-04 Abbott Laboratories Administración transmucosal de composiciones de fármacos para tratar y prevenir trastornos en animales
EP2015632B1 (en) * 2006-04-19 2015-12-02 Mist Pharmaceuticals, LLC Stable hydroalcoholic oral spray formulations and methods
FR2906140B1 (fr) * 2006-09-22 2008-12-05 Philippe Perovitch Forme galenique pour l'administration par voie trans-muqueuse de principes actifs
US20080118441A1 (en) * 2006-11-19 2008-05-22 Washington Joseph A Compositions and methods for the treatment of gastrointestinal conditions
WO2008070795A2 (en) * 2006-12-06 2008-06-12 Somaxon Pharmaceuticals, Inc. Combination therapy using low-dose doxepin for the improvement of sleep
EP2101736A4 (en) * 2006-12-19 2012-09-19 Merial Ltd HOMOGENEOUS PULP AND GEL PREPARATIONS
CA2673049C (en) * 2006-12-22 2016-02-23 Novadel Pharma Inc. Stable anti-nausea oral spray formulations and methods
US20090274722A1 (en) * 2007-01-29 2009-11-05 Ligums John E Therapeutic Composition for the Treatment of BPH and ED
WO2008094873A1 (en) * 2007-01-29 2008-08-07 Ligums John E Therapeutic bph composition
EP2455134B1 (en) 2007-04-19 2016-05-11 Mary Kay, Inc. Magnolia extract containing compositions
CA2687085A1 (en) * 2007-05-10 2008-11-20 Novadel Pharma Inc. Anti-insomnia compositions and methods
US20100035886A1 (en) 2007-06-21 2010-02-11 Veroscience, Llc Parenteral formulations of dopamine agonists
US8741918B2 (en) * 2007-06-21 2014-06-03 Veroscience Llc Parenteral formulations of dopamine agonists
US7867524B2 (en) * 2007-10-05 2011-01-11 David Rowland Energizing formulation
US20110212948A1 (en) * 2008-09-05 2011-09-01 Giuseppe Pippia Treatment of neonate foals with meloxicam
US20100196286A1 (en) * 2008-12-01 2010-08-05 Armer Thomas A Inhalation delivery methods and devices
FR2940120B1 (fr) * 2008-12-19 2012-07-13 Philippe Perovitch Formulation pour l'administration par voie trans-muqueuse de setrons
US8555875B2 (en) 2008-12-23 2013-10-15 Map Pharmaceuticals, Inc. Inhalation devices and related methods for administration of sedative hypnotic compounds
FR2940911B1 (fr) * 2009-01-13 2012-09-21 Philippe Perovitch Formulation pour l'administration par voie trans-muqueuse buccale de molecules antalgiques et/ou anti-spasmodiques
US9352025B2 (en) 2009-06-05 2016-05-31 Veroscience Llc Combination of dopamine agonists plus first phase insulin secretagogues for the treatment of metabolic disorders
US8663709B1 (en) * 2009-08-31 2014-03-04 Fairhaven Health, Llc Composition and method for fertility therapy using nutritional supplements
US20120322782A1 (en) * 2010-02-24 2012-12-20 Pfizer Inc Veterinary compositions
US20140255453A1 (en) * 2013-03-11 2014-09-11 Jaxsen's Llc Herbal ointment for musculoskeletal and joint-related conditions
AP3517A (en) * 2010-04-22 2016-01-11 Genesis Lab Inc Compositions and methods for control of sand flies and other blood sucking insects.
US20130190252A1 (en) * 2010-05-18 2013-07-25 Pharmathen S.A. Pharmaceutical formulation containing lipophilic drugs and milk as a solubilizing/dispensing agent and method for the preparation thereof
JP6194248B2 (ja) 2010-10-28 2017-09-06 パシラ ファーマシューティカルズ インコーポレーテッド 非ステロイド性抗炎症薬の徐放性処方物
US8840937B2 (en) * 2011-08-02 2014-09-23 Walter Joe FORD, JR. Composition and method for recovery from mild traumatic brain injury
NZ623643A (en) * 2011-10-14 2015-12-24 Troy Lab Pty Ltd Meloxicam based formulations for providing analgesia in sheep
SG11201401597TA (en) 2011-11-29 2014-05-29 Jurox Pty Ltd Methods of preserving injectable pharmaceutical compositions comprising a cyclodextrin and a hydrophobic drug
ES2616960T3 (es) 2011-12-21 2017-06-14 Meiji Seika Pharma Co., Ltd. Medicamento de tipo administración local para mejorar la disfagia
WO2013159151A1 (en) * 2012-04-27 2013-10-31 Troy Laboratories Pty Ltd Combination meloxicam and xylazine therapy in animals
EP2855436A4 (en) * 2012-05-24 2016-01-06 Innopharma Inc INJECTABLE APREPITANT FORMULATIONS
AU2013204134B2 (en) * 2012-06-06 2017-02-02 Elanco New Zealand Ectoparasitic Treatment Method and Composition
FR3000896B1 (fr) 2013-01-14 2016-08-26 Philippe Perovitch Forme galenique pour l'administration de principe(s) actif(s) permettant l'induction acceleree du sommeil et/ou le traitement des troubles du sommeil
WO2014153407A2 (en) * 2013-03-19 2014-09-25 Genovus Biotechnologies Inc. Muscle optimization device and method
US10322063B2 (en) 2013-03-19 2019-06-18 Genovus Biotechnologies Inc. Muscle optimization device and method
US10888707B2 (en) 2013-03-19 2021-01-12 Genovus Biotechnologies Inc. Muscle optimization device and method
US9974768B2 (en) 2013-06-13 2018-05-22 Meiji Seika Pharma Co., Ltd. Pharmaceutical for improving dysphagia
KR102088662B1 (ko) * 2013-06-13 2020-03-13 메이지 세이카 파루마 가부시키가이샤 연하장애 개선용 의약품
WO2015093923A1 (es) * 2013-12-19 2015-06-25 Castro Aldrete Jorge Isaac Composiciones veterinarias que comprenden un principio activo y un vehículo farmacéuticamente aceptable para su administración a través de mucosas
US9855227B2 (en) 2015-12-18 2018-01-02 The Procter & Gamble Company Quick dissolving diphenhydramine oral dosage form
US20170232050A1 (en) * 2016-02-16 2017-08-17 David ELLERY Herbal formulation for treating chronic fatigue syndrome
US11331271B2 (en) 2016-05-27 2022-05-17 The Johns Hopkins University Buccal, sublingual and intranasal delivery of fospropofol
EP3541815A4 (en) 2016-11-18 2020-07-15 Pacira Pharmaceuticals, Inc. ZINC MELXICAM COMPLEX MICROPARTICLE MULTIVESICULAR LIPOSOME FORMULATIONS AND METHODS OF MAKING THE SAME
EP4732889A2 (en) 2017-06-07 2026-04-29 Supira Medical, Inc. Intravascular fluid movement devices, systems, and methods of use
KR101816855B1 (ko) 2017-09-29 2018-02-21 서울시립대학교 산학협력단 상황버섯 추출물 또는 베타글루칸을 유효성분으로 함유하는 악취 저감용 조성물
US11511103B2 (en) 2017-11-13 2022-11-29 Shifamed Holdings, Llc Intravascular fluid movement devices, systems, and methods of use
JP7410034B2 (ja) 2018-02-01 2024-01-09 シファメド・ホールディングス・エルエルシー 血管内血液ポンプならびに使用および製造の方法
WO2020028537A1 (en) 2018-07-31 2020-02-06 Shifamed Holdings, Llc Intravascaular blood pumps and methods of use
WO2020073047A1 (en) 2018-10-05 2020-04-09 Shifamed Holdings, Llc Intravascular blood pumps and methods of use
EA202190765A1 (ru) * 2018-10-08 2021-07-01 Троикаа Фармасьютикалз Лимитед Растворы золпидема или его фармацевтически приемлемых солей для оромукозного введения
US12364696B2 (en) 2019-02-27 2025-07-22 Jak Slave Pty Ltd Treatment of autoimmune disease
US11478490B1 (en) 2021-03-30 2022-10-25 Epalex Corporation Fospropofol formulations
US11547714B2 (en) 2020-02-05 2023-01-10 Epalex Corporation Fospropofol salts, methods and compositions
US11439653B1 (en) 2021-03-30 2022-09-13 Epalex Corporation Fospropofol formulations
US11628178B2 (en) 2019-03-26 2023-04-18 Epalex Corporation Fospropofol methods and compositions
WO2021011473A1 (en) 2019-07-12 2021-01-21 Shifamed Holdings, Llc Intravascular blood pumps and methods of manufacture and use
US11654275B2 (en) 2019-07-22 2023-05-23 Shifamed Holdings, Llc Intravascular blood pumps with struts and methods of use and manufacture
EP4010046A4 (en) 2019-08-07 2023-08-30 Calomeni, Michael Catheter blood pumps and collapsible pump housings
EP4034192B1 (en) 2019-09-25 2025-12-24 Supira Medical, Inc. Intravascular blood pump systems and methods of use and control thereof
EP4034221B1 (en) 2019-09-25 2024-11-13 Shifamed Holdings, LLC Catheter blood pumps and collapsible pump housings
WO2021062260A1 (en) 2019-09-25 2021-04-01 Shifamed Holdings, Llc Catheter blood pumps and collapsible blood conduits
EP4072650A4 (en) 2019-12-11 2024-01-10 Shifamed Holdings, LLC Descending aorta and vena cava blood pumps
US12599758B2 (en) 2019-12-19 2026-04-14 Shifamed Holdings, Llc Intravascular blood pumps, motors, and fluid control
IL294601A (en) * 2020-01-10 2022-09-01 Trevi Therapeutics Inc Methods of administration of nalbuphine
WO2021178579A1 (en) * 2020-03-03 2021-09-10 Alte Verde Llc Cannabis treatment of insomnia, pain, and skin conditions
WO2021247283A1 (en) * 2020-06-04 2021-12-09 Amcyte Pharma, Inc. Delivery of aerosolized micromolar composition concentrations
CN111920805B (zh) * 2020-08-14 2021-11-19 山东省妇幼保健院 富马酸氯马斯汀在抗耐甲氧西林金黄葡萄球菌制剂中的应用
EP4208157A1 (en) 2020-09-04 2023-07-12 Elanco Us Inc. Palatable formulations
CN116457021A (zh) * 2020-11-25 2023-07-18 英特维特国际股份有限公司 通过氟尼辛的颊部施用治疗疼痛的方法
JP2024508686A (ja) * 2021-02-05 2024-02-28 エパレックス コーポレーション フォスプロポフォールの方法及び組成物
KR20240015682A (ko) * 2021-05-28 2024-02-05 베테리너리 파마시 코퍼레이션 수용성 복합체 조성물 및 이의 방법
WO2025179244A1 (en) * 2024-02-23 2025-08-28 Phoenix Biotechnology, Inc. Methods and compositions for improving health

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6610711B2 (en) * 1998-05-18 2003-08-26 Pfizer Inc. 4-phenylpiperidines for the treatment of pruritic dermatoses
US20040022903A1 (en) * 2000-06-27 2004-02-05 Shunsuke Takeuchi Hollow cakes containing puffed chocolate and process for producing the same

Family Cites Families (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE632504A (https=) 1962-05-24
US3551554A (en) 1968-08-16 1970-12-29 Crown Zellerbach Corp Enhancing tissue penetration of physiologically active agents with dmso
US3666182A (en) * 1970-04-24 1972-05-30 Chatten Drug & Chem Co Squeeze bottle with means for locating end of delivery tube
US3711606A (en) 1970-09-02 1973-01-16 Crown Zellerbach Corp Enhancing tissue penetration of physiologically active steroidal agents with dmso
US3711602A (en) 1970-10-30 1973-01-16 Crown Zellerbach Corp Compositions for topical application for enhancing tissue penetration of physiologically active agents with dmso
US4122978A (en) * 1975-06-18 1978-10-31 The Gillette Company Pressurized package for dispensing a product in a finely dispersed spray pattern with little dilution by propellant
SE7812207L (sv) 1977-12-01 1979-06-02 Welsh Nat School Med Apparat, forfarande och framstellda produkter for anvendning vid administration av antihistaminer
DE2756113A1 (de) 1977-12-16 1979-06-21 Thomae Gmbh Dr K Neue 4-hydroxy-2h-1,2-benzothiazin- 3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4186855A (en) * 1978-06-19 1980-02-05 Zotos International, Inc. Spray pump actuating and bottle holding device
CA1165240A (en) 1980-07-09 1984-04-10 The Procter & Gamble Company Penetrating topical pharmaceutical compositions
CA1178889A (en) 1980-08-28 1984-12-04 Kenneth S. Su Intranasal formulation
JPS5758615A (en) 1980-09-26 1982-04-08 Nippon Soda Co Ltd Film agnent and its preparation
CA1208558A (en) 1982-10-07 1986-07-29 Kazuo Kigasawa Soft buccal
DE3338978A1 (de) 1982-10-29 1984-05-03 Basf Ag, 6700 Ludwigshafen Verapamil und gallopamil und ihre physiologisch vertraeglichen salze zur resorptiven anwendung auf den schleimhaeuten des mundes, des nasen-rachen-raums und des rektums
US4557943A (en) 1983-10-31 1985-12-10 Advanced Semiconductor Materials America, Inc. Metal-silicide deposition using plasma-enhanced chemical vapor deposition
GB8522453D0 (en) 1985-09-11 1985-10-16 Lilly Industries Ltd Chewable capsules
DE3544692A1 (de) 1985-12-18 1987-06-19 Bayer Ag Dihydropyridinspray, verfahren zu seiner herstellung und seine pharmazeutische verwendung
US4689233A (en) 1986-01-06 1987-08-25 Siegfried Aktiengesellschaft Coronary therapeutic agent in the form of soft gelatin capsules
US4713243A (en) 1986-06-16 1987-12-15 Johnson & Johnson Products, Inc. Bioadhesive extruded film for intra-oral drug delivery and process
JPH0744940B2 (ja) 1986-12-24 1995-05-17 ライオン株式会社 口腔貼付用基材
JPH0645538B2 (ja) 1987-09-30 1994-06-15 日本化薬株式会社 ニトログリセリンスプレー剤
HU199678B (en) * 1988-07-08 1990-03-28 Egyt Gyogyszervegyeszeti Gyar Process for producing aerosols containing nitroglicerol
US5128132A (en) 1988-11-22 1992-07-07 Parnell Pharmaceuticals, Inc. Eriodictyon compositions and methods for treating internal mucous membranes
US4935243A (en) 1988-12-19 1990-06-19 Pharmacaps, Inc. Chewable, edible soft gelatin capsule
JP2656338B2 (ja) 1989-01-31 1997-09-24 日東電工株式会社 口腔粘膜貼付製剤
US5011678A (en) 1989-02-01 1991-04-30 California Biotechnology Inc. Composition and method for administration of pharmaceutically active substances
US5158761A (en) 1989-04-05 1992-10-27 Toko Yakuhin Kogyo Kabushiki Kaisha Spray gel base and spray gel preparation using thereof
DE4007705C1 (https=) 1990-03-10 1991-09-26 G. Pohl-Boskamp Gmbh & Co. Chemisch-Pharmazeutische Fabrik, 2214 Hohenlockstedt, De
ATE164080T1 (de) 1990-05-10 1998-04-15 Bechgaard Int Res Pharmazeutische zubereitung enthaltend n- glykofurole und n-äthylenglykole
US5370862A (en) 1990-06-13 1994-12-06 Schwarz Pharma Ag Pharmaceutical hydrophilic spray containing nitroglycerin for treating angina
US5407663A (en) 1991-04-11 1995-04-18 Eisen; Drore Method of treating inflammatory conditions of the mouth using steroid containing mouthwash which may contain antifungal agents
JP3661131B2 (ja) 1992-02-20 2005-06-15 アスペン ファーマケア ヨーロッパ リミテッド 喫煙抑制具
JPH07506839A (ja) 1992-12-04 1995-07-27 メイヤー・ファーマシューティカル・ラボラトリース・インコーポレーテッド スプレー可能な鎮痛剤組成物およびその使用方法
GB2285921A (en) * 1994-01-31 1995-08-02 Leilani Lea Sublingual administration of medicaments
HU214582B (hu) * 1994-07-26 1998-04-28 EGIS Gyógyszergyár Rt. Porlasztható, vérnyomáscsökkentő hatású gyógyszerkészítmény és eljárás előállítására
UA62917C2 (en) 1995-06-27 2004-01-15 Berinher Inhelheim Kg Medicinal composition for generating propellant-free aerosols
AUPN814496A0 (en) 1996-02-19 1996-03-14 Monash University Dermal penetration enhancer
ES2234010T3 (es) 1996-04-12 2005-06-16 Novadel Pharma Inc. Aerosol bucal polar.
US5955098A (en) 1996-04-12 1999-09-21 Flemington Pharmaceutical Corp. Buccal non polar spray or capsule
US5869082A (en) 1996-04-12 1999-02-09 Flemington Pharmaceutical Corp. Buccal, non-polar spray for nitroglycerin
US20030095927A1 (en) 1997-10-01 2003-05-22 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating muscular and skeletal disorders
US20050163719A1 (en) 1997-10-01 2005-07-28 Dugger Harry A.Iii Buccal, polar and non-polar spray containing diazepam
US20040141923A1 (en) 1997-10-01 2004-07-22 Dugger Harry A. Buccal, polar and non-polar spray containing alprazolam
US7632517B2 (en) 1997-10-01 2009-12-15 Novadel Pharma Inc. Buccal, polar and non-polar spray containing zolpidem
US20030185761A1 (en) 1997-10-01 2003-10-02 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating pain
US20030077229A1 (en) 1997-10-01 2003-04-24 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing cardiovascular or renal drugs
US20030082107A1 (en) 1997-10-01 2003-05-01 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating an infectious disease or cancer
US20040136913A1 (en) 1997-10-01 2004-07-15 Dugger Harry A. Buccal, polar and non-polar spray containing sumatriptan
US20030095926A1 (en) 1997-10-01 2003-05-22 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the gastrointestinal tract or urinary tract
US20040136914A1 (en) 1997-10-01 2004-07-15 Dugger Harry A. Buccal, polar and non-polar spray containing ondansetron
US20030077228A1 (en) 1997-10-01 2003-04-24 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating endocrine disorders
US20030190286A1 (en) 1997-10-01 2003-10-09 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating allergies or asthma
US20050002867A1 (en) 1997-10-01 2005-01-06 Novadel Pharma Inc. Buccal, polar and non-polar sprays containing propofol
EP1952802A3 (en) 1997-10-01 2009-06-17 Novadel Pharma Inc. Buccal, polar and non-polar spray or capsule
US20040136915A1 (en) 1997-10-01 2004-07-15 Dugger Harry A. Buccal, polar and non-polar spray containing atropine
US20030095925A1 (en) * 1997-10-01 2003-05-22 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating metabolic disorders
US20030077227A1 (en) 1997-10-01 2003-04-24 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system
FI974578L (fi) * 1997-12-19 1999-06-20 Orion Yhtymae Oyj Menetelmä levosimendaanin antamiseksi
EP0945134A1 (de) 1998-03-27 1999-09-29 Boehringer Ingelheim Pharma KG Neue galenische Zubereitungsformen von Meloxicam zur oralen Applikation
US6184220B1 (en) 1998-03-27 2001-02-06 Boehringer Ingelheim Pharma Kg Oral suspension of pharmaceutical substance
US6428814B1 (en) 1999-10-08 2002-08-06 Elan Pharma International Ltd. Bioadhesive nanoparticulate compositions having cationic surface stabilizers
US6849263B2 (en) * 1998-12-21 2005-02-01 Generex Pharmaceutical Incorporated Pharmaceutical compositions for buccal delivery of pain relief medications
US6413965B1 (en) * 1999-06-30 2002-07-02 Pfizer Inc. Compositions and treatment for diabetic complications
US6328035B1 (en) * 2000-05-09 2001-12-11 Iep Pharmaceutical Devices Inc. Pneumatic breath actuated inhaler
US20020035107A1 (en) 2000-06-20 2002-03-21 Stefan Henke Highly concentrated stable meloxicam solutions
DE10030345A1 (de) * 2000-06-20 2002-01-10 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen
US20040204413A1 (en) * 2001-01-26 2004-10-14 Joaquina Faour Pharmaceutical compositions containing a COX-II inhibitor and a muscle relaxant
DE10161077A1 (de) * 2001-12-12 2003-06-18 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion
TW200403072A (en) 2002-01-23 2004-03-01 Upjohn Co Combination therapy for the treatment of bacterial infections
FI20022007A0 (fi) * 2002-11-08 2002-11-08 Juvantia Pharma Ltd Oy Oromukosaalinen valmiste ja menetelmä sen valmistamiseksi
GB0229808D0 (en) 2002-12-20 2003-01-29 Glaxo Group Ltd Novel compositions
US8512727B2 (en) * 2003-03-03 2013-08-20 Alkermes Pharma Ireland Limited Nanoparticulate meloxicam formulations
JP2006519770A (ja) * 2003-03-11 2006-08-31 アラキス リミテッド 新規組成物
ES2490595T3 (es) 2005-02-17 2014-09-04 Abbott Laboratories Administración transmucosal de composiciones de fármacos para tratar y prevenir trastornos en animales

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6610711B2 (en) * 1998-05-18 2003-08-26 Pfizer Inc. 4-phenylpiperidines for the treatment of pruritic dermatoses
US20040022903A1 (en) * 2000-06-27 2004-02-05 Shunsuke Takeuchi Hollow cakes containing puffed chocolate and process for producing the same

Also Published As

Publication number Publication date
US20150174060A1 (en) 2015-06-25
WO2006089082A3 (en) 2007-07-12
US8097614B2 (en) 2012-01-17
JP2008530233A (ja) 2008-08-07
EP1848270A4 (en) 2012-07-25
ES2490595T3 (es) 2014-09-04
US20060239928A1 (en) 2006-10-26
CA2597956C (en) 2013-07-09
JP2013067643A (ja) 2013-04-18
AU2006214166A1 (en) 2006-08-24
EP2767163A1 (en) 2014-08-20
JP5681693B2 (ja) 2015-03-11
EP1848270A2 (en) 2007-10-31
CA2597956A1 (en) 2006-08-24
JP5577021B2 (ja) 2014-08-20
EP1848270B1 (en) 2014-05-21
US8940271B2 (en) 2015-01-27
US20120289470A1 (en) 2012-11-15
WO2006089082A2 (en) 2006-08-24

Similar Documents

Publication Publication Date Title
AU2006214166B2 (en) Transmucosal administration of drug compositions for treating and preventing disorders in animals
JP6247685B2 (ja) 実質的に水不溶性の薬物の送達のための医薬組成物
EP2429521B1 (en) Sublingual dexmedetomidine compositions and methods of use thereof
EP2543366B1 (en) Film preparation containing medicament with unpleasant taste
AU2018330329B2 (en) Methods of using dipivefrin
CA3170367A1 (en) Anti-viral compounds and methods for administration thereof
US20110171273A1 (en) Stable anti-nausea oral spray formulations and methods
US20220071898A1 (en) Dipivefrin orally disintegrating tablet formulations
US20180169061A1 (en) Non-aqueous delta9-tetrahydrocannabinol oral liquid formulations
US8722744B2 (en) Galenical form for the administration of paracetamol by transmucous means
AU2013263787B2 (en) Transmucosal administration of drug compositions for treating and preventing disorders in animals
AU2012200031B9 (en) Transmucosal administration of drug compositions for treating and preventing disorders in animals
CA2819963A1 (en) Transmucosal administration of drug compositions for treating and preventing disorders in animals
US20200246363A1 (en) Formulations for the delivery of autophagy stimulating trehalose
HK40036124A (en) Methods of using dipivefrin
HK40036124B (en) Methods of using dipivefrin
HK1168302B (en) Sublingual dexmedetomidine compositions and methods of use thereof

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
PC Assignment registered

Owner name: NOVADEL PHARMA, INC.; ABBOTT LABORATORIES

Free format text: FORMER OWNER WAS: NOVADEL PHARMA, INC.; VELCERA PHARMACEUTICALS, INC

PC Assignment registered

Owner name: ABBOTT LABORATORIES

Free format text: FORMER OWNER WAS: ABBOTT LABORATORIES; NOVADEL PHARMA, INC.

PC Assignment registered

Owner name: ZOETIS BELGIUM S.A.

Free format text: FORMER OWNER WAS: ABBOTT LABORATORIES

MK14 Patent ceased section 143(a) (annual fees not paid) or expired