AU2005321346B2 - Stable solid dispersion of a derivative of vinca alkaloid and process for manufacturing it - Google Patents

Stable solid dispersion of a derivative of vinca alkaloid and process for manufacturing it Download PDF

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Publication number
AU2005321346B2
AU2005321346B2 AU2005321346A AU2005321346A AU2005321346B2 AU 2005321346 B2 AU2005321346 B2 AU 2005321346B2 AU 2005321346 A AU2005321346 A AU 2005321346A AU 2005321346 A AU2005321346 A AU 2005321346A AU 2005321346 B2 AU2005321346 B2 AU 2005321346B2
Authority
AU
Australia
Prior art keywords
solid
dispersion
polyethyleneglycol
stable
stable dispersion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2005321346A
Other languages
English (en)
Other versions
AU2005321346A8 (en
AU2005321346A1 (en
Inventor
Joel Bougaret
Marie-Dominique Ibarra
Elie Leverd
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/025,348 external-priority patent/US20060147518A1/en
Priority claimed from FR0414069A external-priority patent/FR2880274B1/fr
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Publication of AU2005321346A1 publication Critical patent/AU2005321346A1/en
Application granted granted Critical
Publication of AU2005321346B2 publication Critical patent/AU2005321346B2/en
Publication of AU2005321346A8 publication Critical patent/AU2005321346A8/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU2005321346A 2004-12-30 2005-12-20 Stable solid dispersion of a derivative of vinca alkaloid and process for manufacturing it Active AU2005321346B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11/025,348 US20060147518A1 (en) 2004-12-30 2004-12-30 Stable solid dispersion of a derivative of vinca alkaloid and process for manufacturing it
FR0414069A FR2880274B1 (fr) 2004-12-30 2004-12-30 Dispersion solide stable d'un derive d'alcaloides de vinca et son procede de fabrication
US11/025,348 2004-12-30
FR0414069 2004-12-30
PCT/EP2005/056965 WO2006069938A1 (en) 2004-12-30 2005-12-20 Stable solid dispersion of a derivative of vinca alkaloid and process for manufacturing it

Publications (3)

Publication Number Publication Date
AU2005321346A1 AU2005321346A1 (en) 2006-07-06
AU2005321346B2 true AU2005321346B2 (en) 2011-06-23
AU2005321346A8 AU2005321346A8 (en) 2011-10-13

Family

ID=36046982

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005321346A Active AU2005321346B2 (en) 2004-12-30 2005-12-20 Stable solid dispersion of a derivative of vinca alkaloid and process for manufacturing it

Country Status (22)

Country Link
US (1) US9061015B2 (ja)
EP (1) EP1830817B1 (ja)
JP (1) JP5256739B2 (ja)
KR (1) KR101320408B1 (ja)
AR (1) AR052079A1 (ja)
AU (1) AU2005321346B2 (ja)
BR (1) BRPI0519466B8 (ja)
CA (1) CA2591056C (ja)
CY (1) CY1113868T1 (ja)
DK (1) DK1830817T3 (ja)
ES (1) ES2401992T3 (ja)
HR (1) HRP20130276T1 (ja)
IL (1) IL184095A (ja)
MX (1) MX2007008059A (ja)
NZ (1) NZ554793A (ja)
PL (1) PL1830817T3 (ja)
PT (1) PT1830817E (ja)
RS (1) RS52697B (ja)
RU (1) RU2412687C2 (ja)
SI (1) SI1830817T1 (ja)
TW (1) TWI419714B (ja)
WO (1) WO2006069938A1 (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1989212B1 (en) * 2006-02-17 2013-06-19 Cascade Prodrug Inc. Treatment of hyperproliferative diseases with vinca alkaloid n-oxide and analogs
AU2008214199A1 (en) * 2007-02-09 2008-08-14 Poniard Pharmaceuticals, Inc. Encapsulated picoplatin
FR2918566B1 (fr) 2007-07-11 2009-10-09 Pierre Fabre Medicament Sa Composition pharmaceutique stable d'un sel hydrosoluble de vinflunine.
FR2918567B1 (fr) * 2007-07-11 2012-08-03 Pf Medicament Composition pharmaceutique stable d'un sel hydrosoluble de vinorelbine.
RU2730521C2 (ru) 2016-03-09 2020-08-24 Синбиас Фарма АГ Винорелбина монотартрат и его фармацевтическое применение

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020000470A1 (en) * 1993-05-28 2002-01-03 Michael Lanzaro Portable data collection system
US20030212102A1 (en) * 2001-06-12 2003-11-13 Koretke Todd W Novel solid dispersion compositions
WO2003101383A2 (en) * 2002-05-31 2003-12-11 R.P. Scherer Technologies, Inc. Oral pharmaceutical composition for soft capsules containing vinorelbine and method of treatment

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HN1998000115A (es) * 1997-08-21 1999-06-02 Warner Lambert Co Formas de dosificación farmacéuticas sólidas
NL1009780C2 (nl) 1998-07-31 2000-02-01 Peter Hubertus Elisabeth Van D Plantpot.
DE10000792A1 (de) * 2000-01-11 2001-07-19 Bernhard C Lippold Formulierungen von Wirkstoffen in Form einer festen Dispersion
US20020004070A1 (en) * 2000-02-24 2002-01-10 Rudnic Edward M. Antineoplastic product, use and formulation thereof
EP1289560A1 (en) * 2000-06-12 2003-03-12 SmithKline Beecham Corporation Novel solid dispersion compositions
IT1320176B1 (it) * 2000-12-22 2003-11-26 Nicox Sa Dispersioni solide di principi attivi nitrati.
US20050048119A1 (en) * 2002-09-20 2005-03-03 Avinash Nangia Controlled release composition with semi-permeable membrane and poloxamer flux enhancer

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020000470A1 (en) * 1993-05-28 2002-01-03 Michael Lanzaro Portable data collection system
US20030212102A1 (en) * 2001-06-12 2003-11-13 Koretke Todd W Novel solid dispersion compositions
WO2003101383A2 (en) * 2002-05-31 2003-12-11 R.P. Scherer Technologies, Inc. Oral pharmaceutical composition for soft capsules containing vinorelbine and method of treatment

Also Published As

Publication number Publication date
HRP20130276T1 (hr) 2013-04-30
KR101320408B1 (ko) 2013-10-30
DK1830817T3 (da) 2013-04-02
IL184095A (en) 2015-08-31
PT1830817E (pt) 2013-04-01
BRPI0519466B1 (pt) 2020-10-20
RU2412687C2 (ru) 2011-02-27
NZ554793A (en) 2010-04-30
WO2006069938A1 (en) 2006-07-06
JP5256739B2 (ja) 2013-08-07
PL1830817T3 (pl) 2013-06-28
US20080089935A1 (en) 2008-04-17
KR20070094598A (ko) 2007-09-20
CA2591056A1 (en) 2006-07-06
TW200635619A (en) 2006-10-16
CY1113868T1 (el) 2016-07-27
US9061015B2 (en) 2015-06-23
AR052079A1 (es) 2007-02-28
BRPI0519466A2 (pt) 2009-02-03
BRPI0519466B8 (pt) 2021-05-25
RS52697B (en) 2013-08-30
JP2008526711A (ja) 2008-07-24
TWI419714B (zh) 2013-12-21
ES2401992T3 (es) 2013-04-26
SI1830817T1 (sl) 2013-04-30
EP1830817B1 (en) 2013-01-02
RU2007124572A (ru) 2009-01-10
AU2005321346A8 (en) 2011-10-13
AU2005321346A1 (en) 2006-07-06
CA2591056C (en) 2013-11-12
MX2007008059A (es) 2007-07-17
EP1830817A1 (en) 2007-09-12
IL184095A0 (en) 2007-10-31

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Free format text: IN VOL 21, NO 22, PAGE(S) 2597 UNDER THE HEADING PCT APPLICATIONS THAT HAVE ENTERED THE NATIONAL PHASE - NAME INDEX UNDER THE NAME PIERRE FABRE MEDICAMENT, APPLICATION NO. 2005321346, UNDER INID (31), CORRECT THE PRIORITY NUMBER TO 11/025,348

FGA Letters patent sealed or granted (standard patent)