DK1830817T3 - Stabil, fast dispersion af et derivat af vinca-alkaloid og fremgangsmåde til fremstilling heraf - Google Patents

Stabil, fast dispersion af et derivat af vinca-alkaloid og fremgangsmåde til fremstilling heraf

Info

Publication number
DK1830817T3
DK1830817T3 DK05825182.8T DK05825182T DK1830817T3 DK 1830817 T3 DK1830817 T3 DK 1830817T3 DK 05825182 T DK05825182 T DK 05825182T DK 1830817 T3 DK1830817 T3 DK 1830817T3
Authority
DK
Denmark
Prior art keywords
preparing
stable
vinca alkaloid
alkaloid derivative
fixed dispersion
Prior art date
Application number
DK05825182.8T
Other languages
English (en)
Inventor
Elie Leverd
Joel Bougaret
Marie-Dominique Ibarra
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/025,348 external-priority patent/US20060147518A1/en
Priority claimed from FR0414069A external-priority patent/FR2880274B1/fr
Application filed by Pf Medicament filed Critical Pf Medicament
Application granted granted Critical
Publication of DK1830817T3 publication Critical patent/DK1830817T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846Poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK05825182.8T 2004-12-30 2005-12-20 Stabil, fast dispersion af et derivat af vinca-alkaloid og fremgangsmåde til fremstilling heraf DK1830817T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/025,348 US20060147518A1 (en) 2004-12-30 2004-12-30 Stable solid dispersion of a derivative of vinca alkaloid and process for manufacturing it
FR0414069A FR2880274B1 (fr) 2004-12-30 2004-12-30 Dispersion solide stable d'un derive d'alcaloides de vinca et son procede de fabrication
PCT/EP2005/056965 WO2006069938A1 (en) 2004-12-30 2005-12-20 Stable solid dispersion of a derivative of vinca alkaloid and process for manufacturing it

Publications (1)

Publication Number Publication Date
DK1830817T3 true DK1830817T3 (da) 2013-04-02

Family

ID=36046982

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05825182.8T DK1830817T3 (da) 2004-12-30 2005-12-20 Stabil, fast dispersion af et derivat af vinca-alkaloid og fremgangsmåde til fremstilling heraf

Country Status (22)

Country Link
US (1) US9061015B2 (da)
EP (1) EP1830817B1 (da)
JP (1) JP5256739B2 (da)
KR (1) KR101320408B1 (da)
AR (1) AR052079A1 (da)
AU (1) AU2005321346B2 (da)
BR (1) BRPI0519466B8 (da)
CA (1) CA2591056C (da)
CY (1) CY1113868T1 (da)
DK (1) DK1830817T3 (da)
ES (1) ES2401992T3 (da)
HR (1) HRP20130276T1 (da)
IL (1) IL184095A (da)
MX (1) MX2007008059A (da)
NZ (1) NZ554793A (da)
PL (1) PL1830817T3 (da)
PT (1) PT1830817E (da)
RS (1) RS52697B (da)
RU (1) RU2412687C2 (da)
SI (1) SI1830817T1 (da)
TW (1) TWI419714B (da)
WO (1) WO2006069938A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1989212B1 (en) * 2006-02-17 2013-06-19 Cascade Prodrug Inc. Treatment of hyperproliferative diseases with vinca alkaloid n-oxide and analogs
AU2008214199A1 (en) * 2007-02-09 2008-08-14 Poniard Pharmaceuticals, Inc. Encapsulated picoplatin
FR2918566B1 (fr) 2007-07-11 2009-10-09 Pierre Fabre Medicament Sa Composition pharmaceutique stable d'un sel hydrosoluble de vinflunine.
FR2918567B1 (fr) * 2007-07-11 2012-08-03 Pf Medicament Composition pharmaceutique stable d'un sel hydrosoluble de vinorelbine.
RU2730521C2 (ru) 2016-03-09 2020-08-24 Синбиас Фарма АГ Винорелбина монотартрат и его фармацевтическое применение

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6811088B2 (en) * 1993-05-28 2004-11-02 Symbol Technologies, Inc. Portable data collection system
HN1998000115A (es) * 1997-08-21 1999-06-02 Warner Lambert Co Formas de dosificación farmacéuticas sólidas
NL1009780C2 (nl) 1998-07-31 2000-02-01 Peter Hubertus Elisabeth Van D Plantpot.
DE10000792A1 (de) * 2000-01-11 2001-07-19 Bernhard C Lippold Formulierungen von Wirkstoffen in Form einer festen Dispersion
US20020004070A1 (en) * 2000-02-24 2002-01-10 Rudnic Edward M. Antineoplastic product, use and formulation thereof
EP1289560A1 (en) * 2000-06-12 2003-03-12 SmithKline Beecham Corporation Novel solid dispersion compositions
IT1320176B1 (it) * 2000-12-22 2003-11-26 Nicox Sa Dispersioni solide di principi attivi nitrati.
US20030212102A1 (en) * 2001-06-12 2003-11-13 Koretke Todd W Novel solid dispersion compositions
EP1530459B1 (en) * 2002-05-31 2010-03-31 R.P. Scherer Technologies, LLC Oral pharmaceutical composition for soft capsules containing vinorelbine and method of treatment
US20050048119A1 (en) * 2002-09-20 2005-03-03 Avinash Nangia Controlled release composition with semi-permeable membrane and poloxamer flux enhancer

Also Published As

Publication number Publication date
HRP20130276T1 (hr) 2013-04-30
KR101320408B1 (ko) 2013-10-30
IL184095A (en) 2015-08-31
AU2005321346B2 (en) 2011-06-23
PT1830817E (pt) 2013-04-01
BRPI0519466B1 (pt) 2020-10-20
RU2412687C2 (ru) 2011-02-27
NZ554793A (en) 2010-04-30
WO2006069938A1 (en) 2006-07-06
JP5256739B2 (ja) 2013-08-07
PL1830817T3 (pl) 2013-06-28
US20080089935A1 (en) 2008-04-17
KR20070094598A (ko) 2007-09-20
CA2591056A1 (en) 2006-07-06
TW200635619A (en) 2006-10-16
CY1113868T1 (el) 2016-07-27
US9061015B2 (en) 2015-06-23
AR052079A1 (es) 2007-02-28
BRPI0519466A2 (pt) 2009-02-03
BRPI0519466B8 (pt) 2021-05-25
RS52697B (en) 2013-08-30
JP2008526711A (ja) 2008-07-24
TWI419714B (zh) 2013-12-21
ES2401992T3 (es) 2013-04-26
SI1830817T1 (sl) 2013-04-30
EP1830817B1 (en) 2013-01-02
RU2007124572A (ru) 2009-01-10
AU2005321346A8 (en) 2011-10-13
AU2005321346A1 (en) 2006-07-06
CA2591056C (en) 2013-11-12
MX2007008059A (es) 2007-07-17
EP1830817A1 (en) 2007-09-12
IL184095A0 (en) 2007-10-31

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