AU2005304093A1 - Antimicroboial active ingredient-containing silicone elastomers - Google Patents
Antimicroboial active ingredient-containing silicone elastomers Download PDFInfo
- Publication number
- AU2005304093A1 AU2005304093A1 AU2005304093A AU2005304093A AU2005304093A1 AU 2005304093 A1 AU2005304093 A1 AU 2005304093A1 AU 2005304093 A AU2005304093 A AU 2005304093A AU 2005304093 A AU2005304093 A AU 2005304093A AU 2005304093 A1 AU2005304093 A1 AU 2005304093A1
- Authority
- AU
- Australia
- Prior art keywords
- silicone
- active ingredient
- weight
- polymer
- suspension
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 229920002379 silicone rubber Polymers 0.000 title claims description 67
- 239000004480 active ingredient Substances 0.000 title description 74
- MYSWGUAQZAJSOK-UHFFFAOYSA-N ciprofloxacin Chemical compound C12=CC(N3CCNCC3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 MYSWGUAQZAJSOK-UHFFFAOYSA-N 0.000 claims description 54
- 239000000203 mixture Substances 0.000 claims description 31
- 229920001296 polysiloxane Polymers 0.000 claims description 27
- 229960003405 ciprofloxacin Drugs 0.000 claims description 26
- 150000001875 compounds Chemical class 0.000 claims description 22
- 150000003839 salts Chemical class 0.000 claims description 17
- 238000000034 method Methods 0.000 claims description 13
- 229920001971 elastomer Polymers 0.000 claims description 12
- 230000000845 anti-microbial effect Effects 0.000 claims description 11
- 239000000806 elastomer Substances 0.000 claims description 9
- 238000004519 manufacturing process Methods 0.000 claims description 9
- 238000002156 mixing Methods 0.000 claims description 4
- 210000001635 urinary tract Anatomy 0.000 claims description 4
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical compound C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 claims 4
- 239000004599 antimicrobial Substances 0.000 claims 1
- 238000007493 shaping process Methods 0.000 claims 1
- 210000003462 vein Anatomy 0.000 claims 1
- -1 polysiloxane Polymers 0.000 description 52
- 229920000642 polymer Polymers 0.000 description 51
- 239000000725 suspension Substances 0.000 description 50
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 33
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 30
- 239000004945 silicone rubber Substances 0.000 description 29
- 239000002245 particle Substances 0.000 description 26
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 22
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 20
- 238000004132 cross linking Methods 0.000 description 17
- 229960003237 betaine Drugs 0.000 description 15
- 125000001624 naphthyl group Chemical group 0.000 description 15
- 238000010058 rubber compounding Methods 0.000 description 15
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 14
- 239000000463 material Substances 0.000 description 14
- 229920002554 vinyl polymer Polymers 0.000 description 14
- 239000011324 bead Substances 0.000 description 13
- 239000003054 catalyst Substances 0.000 description 13
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- 208000015181 infectious disease Diseases 0.000 description 13
- 229930182566 Gentamicin Natural products 0.000 description 12
- CEAZRRDELHUEMR-URQXQFDESA-N Gentamicin Chemical compound O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N CEAZRRDELHUEMR-URQXQFDESA-N 0.000 description 12
- 239000013543 active substance Substances 0.000 description 12
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- 238000009826 distribution Methods 0.000 description 11
- 230000000694 effects Effects 0.000 description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 11
- GSDSWSVVBLHKDQ-UHFFFAOYSA-N 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid Chemical compound FC1=CC(C(C(C(O)=O)=C2)=O)=C3N2C(C)COC3=C1N1CCN(C)CC1 GSDSWSVVBLHKDQ-UHFFFAOYSA-N 0.000 description 10
- 229920001817 Agar Polymers 0.000 description 10
- 239000008272 agar Substances 0.000 description 10
- 229960001229 ciprofloxacin hydrochloride Drugs 0.000 description 10
- DIOIOSKKIYDRIQ-UHFFFAOYSA-N ciprofloxacin hydrochloride Chemical compound Cl.C12=CC(N3CCNCC3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 DIOIOSKKIYDRIQ-UHFFFAOYSA-N 0.000 description 10
- 239000002609 medium Substances 0.000 description 10
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- 229960001180 norfloxacin Drugs 0.000 description 10
- OGJPXUAPXNRGGI-UHFFFAOYSA-N norfloxacin Chemical compound C1=C2N(CC)C=C(C(O)=O)C(=O)C2=CC(F)=C1N1CCNCC1 OGJPXUAPXNRGGI-UHFFFAOYSA-N 0.000 description 10
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- 239000011521 glass Substances 0.000 description 8
- 229930027917 kanamycin Natural products 0.000 description 8
- 229960000318 kanamycin Drugs 0.000 description 8
- SBUJHOSQTJFQJX-NOAMYHISSA-N kanamycin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N SBUJHOSQTJFQJX-NOAMYHISSA-N 0.000 description 8
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- 239000011159 matrix material Substances 0.000 description 8
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- 241000894006 Bacteria Species 0.000 description 7
- 241000191967 Staphylococcus aureus Species 0.000 description 7
- 238000006243 chemical reaction Methods 0.000 description 7
- 238000000227 grinding Methods 0.000 description 7
- 239000001257 hydrogen Substances 0.000 description 7
- 229910052739 hydrogen Inorganic materials 0.000 description 7
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 7
- 229920003023 plastic Polymers 0.000 description 7
- 239000004033 plastic Substances 0.000 description 7
- 230000000052 comparative effect Effects 0.000 description 6
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 6
- 238000006459 hydrosilylation reaction Methods 0.000 description 6
- 239000004615 ingredient Substances 0.000 description 6
- 230000005764 inhibitory process Effects 0.000 description 6
- 150000002739 metals Chemical class 0.000 description 6
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 6
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 6
- 230000002940 repellent Effects 0.000 description 6
- 208000032840 Catheter-Related Infections Diseases 0.000 description 5
- 241000588724 Escherichia coli Species 0.000 description 5
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 5
- 125000000217 alkyl group Chemical group 0.000 description 5
- 239000003242 anti bacterial agent Substances 0.000 description 5
- 239000003795 chemical substances by application Substances 0.000 description 5
- 239000004205 dimethyl polysiloxane Substances 0.000 description 5
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical group [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 description 5
- IDYZIJYBMGIQMJ-UHFFFAOYSA-N enoxacin Chemical compound N1=C2N(CC)C=C(C(O)=O)C(=O)C2=CC(F)=C1N1CCNCC1 IDYZIJYBMGIQMJ-UHFFFAOYSA-N 0.000 description 5
- 229960002549 enoxacin Drugs 0.000 description 5
- 150000003840 hydrochlorides Chemical class 0.000 description 5
- 239000003112 inhibitor Substances 0.000 description 5
- 229960003702 moxifloxacin Drugs 0.000 description 5
- FABPRXSRWADJSP-MEDUHNTESA-N moxifloxacin Chemical compound COC1=C(N2C[C@H]3NCCC[C@H]3C2)C(F)=CC(C(C(C(O)=O)=C2)=O)=C1N2C1CC1 FABPRXSRWADJSP-MEDUHNTESA-N 0.000 description 5
- FHFYDNQZQSQIAI-UHFFFAOYSA-N pefloxacin Chemical compound C1=C2N(CC)C=C(C(O)=O)C(=O)C2=CC(F)=C1N1CCN(C)CC1 FHFYDNQZQSQIAI-UHFFFAOYSA-N 0.000 description 5
- 239000007787 solid Substances 0.000 description 5
- 229910052684 Cerium Inorganic materials 0.000 description 4
- 241000588914 Enterobacter Species 0.000 description 4
- OJMMVQQUTAEWLP-UHFFFAOYSA-N Lincomycin Natural products CN1CC(CCC)CC1C(=O)NC(C(C)O)C1C(O)C(O)C(O)C(SC)O1 OJMMVQQUTAEWLP-UHFFFAOYSA-N 0.000 description 4
- URWAJWIAIPFPJE-UHFFFAOYSA-N Rickamicin Natural products O1CC(O)(C)C(NC)C(O)C1OC1C(O)C(OC2C(CC=C(CN)O2)N)C(N)CC1N URWAJWIAIPFPJE-UHFFFAOYSA-N 0.000 description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 4
- 239000002253 acid Substances 0.000 description 4
- 229910052782 aluminium Inorganic materials 0.000 description 4
- 229960004821 amikacin Drugs 0.000 description 4
- LKCWBDHBTVXHDL-RMDFUYIESA-N amikacin Chemical compound O([C@@H]1[C@@H](N)C[C@H]([C@@H]([C@H]1O)O[C@@H]1[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O1)O)NC(=O)[C@@H](O)CCN)[C@H]1O[C@H](CN)[C@@H](O)[C@H](O)[C@H]1O LKCWBDHBTVXHDL-RMDFUYIESA-N 0.000 description 4
- 229940126575 aminoglycoside Drugs 0.000 description 4
- 229940088710 antibiotic agent Drugs 0.000 description 4
- 229940045985 antineoplastic platinum compound Drugs 0.000 description 4
- 150000004649 carbonic acid derivatives Chemical class 0.000 description 4
- 229960004621 cinoxacin Drugs 0.000 description 4
- VDUWPHTZYNWKRN-UHFFFAOYSA-N cinoxacin Chemical compound C1=C2N(CC)N=C(C(O)=O)C(=O)C2=CC2=C1OCO2 VDUWPHTZYNWKRN-UHFFFAOYSA-N 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 4
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- 229910052747 lanthanoid Inorganic materials 0.000 description 4
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- 229960000808 netilmicin Drugs 0.000 description 4
- ZBGPYVZLYBDXKO-HILBYHGXSA-N netilmycin Chemical compound O([C@@H]1[C@@H](N)C[C@H]([C@@H]([C@H]1O)O[C@@H]1[C@]([C@H](NC)[C@@H](O)CO1)(C)O)NCC)[C@H]1OC(CN)=CC[C@H]1N ZBGPYVZLYBDXKO-HILBYHGXSA-N 0.000 description 4
- 244000052769 pathogen Species 0.000 description 4
- 229960004236 pefloxacin Drugs 0.000 description 4
- JOHZPMXAZQZXHR-UHFFFAOYSA-N pipemidic acid Chemical compound N1=C2N(CC)C=C(C(O)=O)C(=O)C2=CN=C1N1CCNCC1 JOHZPMXAZQZXHR-UHFFFAOYSA-N 0.000 description 4
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- NLVFBUXFDBBNBW-PBSUHMDJSA-N tobramycin Chemical compound N[C@@H]1C[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N NLVFBUXFDBBNBW-PBSUHMDJSA-N 0.000 description 4
- 238000011282 treatment Methods 0.000 description 4
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- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
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- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical group [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 3
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
- A61L29/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/04—Macromolecular materials
- A61L29/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004054040.3 | 2004-11-05 | ||
| DE102004054040A DE102004054040A1 (de) | 2004-11-05 | 2004-11-05 | Wirkstoffhaltige Silikonelastomere |
| PCT/EP2005/011365 WO2006050806A1 (en) | 2004-11-05 | 2005-10-22 | Antimicroboial active ingredient-containing silicone elastomers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2005304093A1 true AU2005304093A1 (en) | 2006-05-18 |
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|---|---|---|---|
| AU2005304093A Abandoned AU2005304093A1 (en) | 2004-11-05 | 2005-10-22 | Antimicroboial active ingredient-containing silicone elastomers |
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| Country | Link |
|---|---|
| US (1) | US20090076480A1 (enExample) |
| EP (1) | EP1809348A1 (enExample) |
| JP (1) | JP2008518699A (enExample) |
| AU (1) | AU2005304093A1 (enExample) |
| CA (1) | CA2586166A1 (enExample) |
| DE (1) | DE102004054040A1 (enExample) |
| IL (1) | IL182619A0 (enExample) |
| RU (1) | RU2007120703A (enExample) |
| TW (1) | TW200630128A (enExample) |
| WO (1) | WO2006050806A1 (enExample) |
| ZA (1) | ZA200703505B (enExample) |
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|---|---|---|---|---|
| DE102006020644A1 (de) * | 2006-04-28 | 2007-10-31 | Bayer Innovation Gmbh | Antiseptikahaltige Silikonelastomere |
| DE102007000214A1 (de) * | 2007-04-10 | 2008-10-16 | Invendo Medical Gmbh | Verfahren zur Reibungsverringerung eines medizintechnischen Kautschukschlauchs |
| US8747883B2 (en) | 2010-06-02 | 2014-06-10 | Princeton Trade & Technology, Inc. | Medical item for long term drug release |
| US11033624B2 (en) | 2010-06-02 | 2021-06-15 | Novaflux Inc. | Medical item for prevention and treatment of ear infection |
| US20130172192A1 (en) * | 2012-01-04 | 2013-07-04 | Momentive Performance Materials Inc. | Ionically cross-linked silicone composition |
| WO2015168642A1 (en) | 2014-05-02 | 2015-11-05 | Labib Mohamed E | Drug-releasing device usable in mucosal body cavities |
| WO2017194099A1 (de) | 2016-05-11 | 2017-11-16 | Wacker Chemie Ag | Antimikrobielles vernetztes siliconpolymer |
| EP3886927B1 (en) * | 2018-11-29 | 2023-06-14 | Ethicon, Inc | Low temperature cured silicone lubricious coatings |
| WO2021053996A1 (ja) * | 2019-09-17 | 2021-03-25 | テルモ株式会社 | 医療器具および医療器具の製造方法 |
| US11712229B2 (en) | 2020-05-28 | 2023-08-01 | Ethicon, Inc. | Systems, devices and methods for dispensing and curing silicone based topical skin adhesives |
| US11718753B2 (en) | 2020-05-28 | 2023-08-08 | Ethicon, Inc. | Topical skin closure compositions and systems |
| US11518604B2 (en) | 2020-05-28 | 2022-12-06 | Ethicon, Inc. | Systems, methods and devices for aerosol spraying of silicone based topical skin adhesives for sealing wounds |
| US11589867B2 (en) | 2020-05-28 | 2023-02-28 | Ethicon, Inc. | Anisotropic wound closure systems |
| US12465577B2 (en) | 2020-05-28 | 2025-11-11 | Ethicon, Inc. | Antimicrobial topical skin closure compositions and systems |
| US11479669B2 (en) | 2020-05-28 | 2022-10-25 | Ethicon, Inc. | Topical skin closure compositions and systems |
| US11820890B2 (en) | 2021-04-01 | 2023-11-21 | Stratasys Inc | Pulverulent thermoplastic polymer blends |
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| BE494972A (enExample) * | 1949-04-07 | |||
| US3002951A (en) * | 1959-04-27 | 1961-10-03 | Dow Corning | Method of polymerizing cyclic diorganosiloxanes |
| NL129346C (enExample) * | 1966-06-23 | |||
| US3715334A (en) * | 1970-11-27 | 1973-02-06 | Gen Electric | Platinum-vinylsiloxanes |
| BE791632A (fr) * | 1971-11-20 | 1973-05-21 | Schering Ag | Supports a base de caoutchouc siliconique pour agents medicamenteux |
| US4343788A (en) * | 1979-06-29 | 1982-08-10 | The Procter & Gamble Company | Antimicrobial polymer compositions |
| JP2636838B2 (ja) * | 1986-01-13 | 1997-07-30 | ユニチカ株式会社 | 抗菌剤徐放性導尿カテーテル |
| US5019096A (en) * | 1988-02-11 | 1991-05-28 | Trustees Of Columbia University In The City Of New York | Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same |
| US5261896A (en) * | 1990-01-10 | 1993-11-16 | Rochester Medical Corporation | Sustained release bactericidal cannula |
| DE4428458A1 (de) * | 1994-08-11 | 1996-02-15 | Bayer Ag | Cycloaliphatische thermoplastische Polyurethanelastomere |
| DE19638570A1 (de) * | 1996-09-20 | 1998-03-26 | Bayer Ag | Wirkstoffhaltige thermoplastische Polyurethane |
| DE19812160C1 (de) * | 1998-03-20 | 1999-07-08 | Bayer Ag | Formkörper aus wirkstoffhaltigen thermoplastischen Polyurethanen |
| ATE228300T1 (de) * | 1998-11-12 | 2002-12-15 | Bayer Ag | Wirkstoffhaltige polyetherblockamide |
| KR100564229B1 (ko) * | 2002-06-25 | 2006-03-28 | (주)마이크로 사이언스 테크 | 항균성 또는 항응혈성 의료용품 및 이의 제조방법 |
| US7285570B2 (en) * | 2003-04-17 | 2007-10-23 | The Procter & Gamble Company | Compositions and methods for regulating mammalian keratinous tissue |
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-
2005
- 2005-10-22 RU RU2007120703/15A patent/RU2007120703A/ru not_active Application Discontinuation
- 2005-10-22 JP JP2007539494A patent/JP2008518699A/ja active Pending
- 2005-10-22 EP EP05813711A patent/EP1809348A1/en not_active Withdrawn
- 2005-10-22 WO PCT/EP2005/011365 patent/WO2006050806A1/en not_active Ceased
- 2005-10-22 AU AU2005304093A patent/AU2005304093A1/en not_active Abandoned
- 2005-10-22 US US11/718,587 patent/US20090076480A1/en not_active Abandoned
- 2005-10-22 CA CA002586166A patent/CA2586166A1/en not_active Abandoned
- 2005-11-04 TW TW094138659A patent/TW200630128A/zh unknown
-
2007
- 2007-04-17 IL IL182619A patent/IL182619A0/en not_active IP Right Cessation
- 2007-05-02 ZA ZA200703505A patent/ZA200703505B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006050806A1 (en) | 2006-05-18 |
| ZA200703505B (en) | 2008-09-25 |
| US20090076480A1 (en) | 2009-03-19 |
| IL182619A0 (en) | 2007-07-24 |
| EP1809348A1 (en) | 2007-07-25 |
| TW200630128A (en) | 2006-09-01 |
| DE102004054040A1 (de) | 2006-05-11 |
| JP2008518699A (ja) | 2008-06-05 |
| RU2007120703A (ru) | 2008-12-10 |
| CA2586166A1 (en) | 2006-05-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |