AU2005278903A1 - Glycerol branched polyethylene glycol human growth hormone conjugates, process for their preparation, and methods of use thereof - Google Patents
Glycerol branched polyethylene glycol human growth hormone conjugates, process for their preparation, and methods of use thereof Download PDFInfo
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- AU2005278903A1 AU2005278903A1 AU2005278903A AU2005278903A AU2005278903A1 AU 2005278903 A1 AU2005278903 A1 AU 2005278903A1 AU 2005278903 A AU2005278903 A AU 2005278903A AU 2005278903 A AU2005278903 A AU 2005278903A AU 2005278903 A1 AU2005278903 A1 AU 2005278903A1
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- Prior art keywords
- hgh
- peg
- growth hormone
- conjugate
- seq
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60594504P | 2004-08-31 | 2004-08-31 | |
| US60/605,945 | 2004-08-31 | ||
| PCT/IB2005/002939 WO2006024953A2 (en) | 2004-08-31 | 2005-08-25 | Glycerol branched polyethylene glycol human growth hormone conjugates, process for their preparation, and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
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| AU2005278903A1 true AU2005278903A1 (en) | 2006-03-09 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2005278903A Abandoned AU2005278903A1 (en) | 2004-08-31 | 2005-08-25 | Glycerol branched polyethylene glycol human growth hormone conjugates, process for their preparation, and methods of use thereof |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1789092A2 (ru) |
| JP (1) | JP2008511610A (ru) |
| KR (1) | KR20070042567A (ru) |
| CN (1) | CN101010105A (ru) |
| AP (1) | AP2007003919A0 (ru) |
| AR (1) | AR050851A1 (ru) |
| AU (1) | AU2005278903A1 (ru) |
| BR (1) | BRPI0515118A (ru) |
| CA (1) | CA2577999A1 (ru) |
| CR (1) | CR8942A (ru) |
| EA (1) | EA200700380A1 (ru) |
| EC (1) | ECSP077281A (ru) |
| GT (1) | GT200500235A (ru) |
| IL (1) | IL181085A0 (ru) |
| MA (1) | MA28908B1 (ru) |
| MX (1) | MX2007002441A (ru) |
| NL (1) | NL1029828C2 (ru) |
| NO (1) | NO20071322L (ru) |
| PE (1) | PE20060654A1 (ru) |
| TN (1) | TNSN07078A1 (ru) |
| TW (1) | TW200621291A (ru) |
| UY (1) | UY29088A1 (ru) |
| WO (1) | WO2006024953A2 (ru) |
| ZA (1) | ZA200701802B (ru) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69838552T2 (de) | 1997-07-14 | 2008-05-21 | Bolder Biotechnology, Inc., Louisville | Derivate des wachstumshormons und verwandte proteine |
| US7495087B2 (en) | 1997-07-14 | 2009-02-24 | Bolder Biotechnology, Inc. | Cysteine muteins in the C-D loop of human interleukin-11 |
| EP2305804B1 (en) | 1999-01-14 | 2015-05-06 | Bolder Biotechnology, Inc. | MonoPEGylated human growth hormone |
| US7855279B2 (en) | 2005-09-27 | 2010-12-21 | Amunix Operating, Inc. | Unstructured recombinant polymers and uses thereof |
| EP1834963A1 (en) * | 2006-03-13 | 2007-09-19 | Siegfried Ltd. | Di-polymer protein conjugates and processes for their preparation |
| US20090117077A1 (en) * | 2006-05-12 | 2009-05-07 | Dong-A Pharm. Co., Ltd. | Polyethylene glycol-interferon alpha conjugate |
| JP2008069073A (ja) * | 2006-09-12 | 2008-03-27 | Yokohama Tlo Co Ltd | ラクトフェリン複合体及びその製造方法 |
| KR101079993B1 (ko) * | 2006-11-17 | 2011-11-04 | 동아제약주식회사 | 폴리에틸렌글리콜 과립구 콜로니 자극인자 접합체 |
| CL2008002399A1 (es) | 2007-08-16 | 2009-01-02 | Pharmaessentia Corp | Conjugado sustancialmente puro que posee una porcion polimerica, una porcion proteica (interferon alfa 2b) y un ligante alifatico de 1 a 10 atomos de carbono, util en el tratamiento de las hepatitis b o c. |
| EP2300501B1 (en) * | 2008-07-23 | 2014-08-20 | Hanmi Science Co., Ltd. | A polypeptide complex comprising non-peptidyl polymer having three functional ends |
| EA020347B1 (ru) | 2008-07-31 | 2014-10-30 | Фармаиссэншиа Корп. | Пептид-полимерные конъюгаты |
| US8535655B2 (en) | 2008-10-10 | 2013-09-17 | Polyactiva Pty Ltd. | Biodegradable polymer—bioactive moiety conjugates |
| WO2010040187A1 (en) | 2008-10-10 | 2010-04-15 | The Bionic Ear Institute | Polymer-bioactive agent conjugates |
| EP2355853B1 (en) * | 2008-10-10 | 2016-12-07 | Polyactiva Pty Ltd | Biodegradable polymer - bioactive moiety conjugates |
| US8680050B2 (en) | 2009-02-03 | 2014-03-25 | Amunix Operating Inc. | Growth hormone polypeptides fused to extended recombinant polypeptides and methods of making and using same |
| BR122021021381B1 (pt) | 2009-02-03 | 2023-05-16 | Amunix Pharmaceuticals, Inc | Método de aprimoramento de uma propriedade de uma proteína biologicamente ativa |
| US8703717B2 (en) | 2009-02-03 | 2014-04-22 | Amunix Operating Inc. | Growth hormone polypeptides and methods of making and using same |
| US9849188B2 (en) | 2009-06-08 | 2017-12-26 | Amunix Operating Inc. | Growth hormone polypeptides and methods of making and using same |
| US8841249B2 (en) | 2009-08-06 | 2014-09-23 | Novo Nordisk A/S | Growth hormones with prolonged in-vivo efficacy |
| CN101831067A (zh) * | 2010-05-31 | 2010-09-15 | 王二新 | 聚乙二醇脂类缀合物及其在制备药物中的应用 |
| EP2446898A1 (en) | 2010-09-30 | 2012-05-02 | Laboratorios Del. Dr. Esteve, S.A. | Use of growth hormone to enhance the immune response in immunosuppressed patients |
| CN102367290B (zh) * | 2011-04-26 | 2013-05-08 | 厦门赛诺邦格生物科技有限公司 | 链官能化的多级支化聚乙二醇及其合成方法 |
| WO2014110867A1 (zh) * | 2013-01-17 | 2014-07-24 | 厦门赛诺邦格生物科技有限公司 | 一种单一官能化的支化聚乙二醇及其修饰的生物相关物质 |
| CN104877127B (zh) | 2015-06-23 | 2017-11-10 | 厦门赛诺邦格生物科技股份有限公司 | 一种八臂聚乙二醇衍生物、制备方法及其修饰的生物相关物质 |
| MY191506A (en) | 2014-11-06 | 2022-06-28 | Pharmaessentia Corp | Dosage regimen for pegylated interferon |
| US11518781B2 (en) | 2017-12-29 | 2022-12-06 | Hoffmann-La Roche Inc. | Process for providing PEGylated protein composition |
| US20200362002A1 (en) * | 2017-12-29 | 2020-11-19 | Hoffmann-La Roche Inc. | Process for providing pegylated protein composition |
| US20200323993A1 (en) * | 2017-12-29 | 2020-10-15 | Hoffmann-La Roche Inc. | Process for providing pegylated protein composition |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993000109A1 (en) * | 1991-06-28 | 1993-01-07 | Genentech, Inc. | Method of stimulating immune response using growth hormone |
| JP3092531B2 (ja) * | 1996-11-05 | 2000-09-25 | 日本油脂株式会社 | コハク酸イミジル基置換ポリオキシアルキレン誘導体の製造方法 |
| DE69838552T2 (de) * | 1997-07-14 | 2008-05-21 | Bolder Biotechnology, Inc., Louisville | Derivate des wachstumshormons und verwandte proteine |
| JP3921781B2 (ja) * | 1998-02-12 | 2007-05-30 | 日本油脂株式会社 | カルボキシル基含有ポリオキシアルキレン化合物 |
| EP2305804B1 (en) * | 1999-01-14 | 2015-05-06 | Bolder Biotechnology, Inc. | MonoPEGylated human growth hormone |
| HUP0500997A2 (en) * | 2001-11-20 | 2007-11-28 | Pharmacia Corp | Chemically-modified human growth hormone conjugates |
| ES2897470T3 (es) * | 2002-09-09 | 2022-03-01 | Nektar Therapeutics | Alcanales poliméricos solubles en agua |
| JP4412461B2 (ja) * | 2002-11-20 | 2010-02-10 | 日油株式会社 | 修飾された生体関連物質、その製造方法および中間体 |
| EP1581260B1 (en) * | 2002-12-31 | 2014-09-17 | Nektar Therapeutics | Polymeric reagents comprising a ketone or a related functional group |
| WO2005000360A2 (en) * | 2003-05-23 | 2005-01-06 | Nektar Therapeutics Al, Corporation | Peg derivatives having an amidocarbonate linkage |
-
2005
- 2005-08-25 KR KR1020077004912A patent/KR20070042567A/ko not_active Application Discontinuation
- 2005-08-25 MX MX2007002441A patent/MX2007002441A/es unknown
- 2005-08-25 JP JP2007529040A patent/JP2008511610A/ja active Pending
- 2005-08-25 BR BRPI0515118-0A patent/BRPI0515118A/pt not_active IP Right Cessation
- 2005-08-25 WO PCT/IB2005/002939 patent/WO2006024953A2/en active Application Filing
- 2005-08-25 CA CA002577999A patent/CA2577999A1/en not_active Abandoned
- 2005-08-25 AP AP2007003919A patent/AP2007003919A0/xx unknown
- 2005-08-25 CN CNA2005800291171A patent/CN101010105A/zh active Pending
- 2005-08-25 AU AU2005278903A patent/AU2005278903A1/en not_active Abandoned
- 2005-08-25 EP EP05784225A patent/EP1789092A2/en not_active Withdrawn
- 2005-08-25 EA EA200700380A patent/EA200700380A1/ru unknown
- 2005-08-26 PE PE2005000991A patent/PE20060654A1/es not_active Application Discontinuation
- 2005-08-29 AR ARP050103612A patent/AR050851A1/es unknown
- 2005-08-29 UY UY29088A patent/UY29088A1/es not_active Application Discontinuation
- 2005-08-30 TW TW094129583A patent/TW200621291A/zh unknown
- 2005-08-30 GT GT200500235A patent/GT200500235A/es unknown
- 2005-08-30 NL NL1029828A patent/NL1029828C2/nl not_active IP Right Cessation
-
2007
- 2007-01-31 IL IL181085A patent/IL181085A0/en unknown
- 2007-02-26 CR CR8942A patent/CR8942A/es not_active Application Discontinuation
- 2007-02-27 EC EC2007007281A patent/ECSP077281A/es unknown
- 2007-02-27 TN TNP2007000078A patent/TNSN07078A1/fr unknown
- 2007-02-28 MA MA29724A patent/MA28908B1/fr unknown
- 2007-02-28 ZA ZA200701802A patent/ZA200701802B/xx unknown
- 2007-03-09 NO NO20071322A patent/NO20071322L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| TNSN07078A1 (fr) | 2008-06-02 |
| CN101010105A (zh) | 2007-08-01 |
| ECSP077281A (es) | 2007-03-29 |
| MA28908B1 (fr) | 2007-10-01 |
| AP2007003919A0 (en) | 2007-02-28 |
| IL181085A0 (en) | 2007-07-04 |
| MX2007002441A (es) | 2007-05-04 |
| CA2577999A1 (en) | 2006-03-09 |
| TW200621291A (en) | 2006-07-01 |
| EP1789092A2 (en) | 2007-05-30 |
| GT200500235A (es) | 2006-03-21 |
| UY29088A1 (es) | 2006-03-31 |
| NL1029828A1 (nl) | 2006-03-01 |
| CR8942A (es) | 2007-08-16 |
| ZA200701802B (en) | 2008-08-27 |
| WO2006024953A2 (en) | 2006-03-09 |
| JP2008511610A (ja) | 2008-04-17 |
| NO20071322L (no) | 2007-05-29 |
| BRPI0515118A (pt) | 2008-07-01 |
| AR050851A1 (es) | 2006-11-29 |
| NL1029828C2 (nl) | 2006-10-20 |
| KR20070042567A (ko) | 2007-04-23 |
| PE20060654A1 (es) | 2006-08-12 |
| WO2006024953A3 (en) | 2007-01-18 |
| EA200700380A1 (ru) | 2007-10-26 |
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