AU2005274788A1 - Biomarkers of neurodegenerative disease - Google Patents

Biomarkers of neurodegenerative disease Download PDF

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Publication number
AU2005274788A1
AU2005274788A1 AU2005274788A AU2005274788A AU2005274788A1 AU 2005274788 A1 AU2005274788 A1 AU 2005274788A1 AU 2005274788 A AU2005274788 A AU 2005274788A AU 2005274788 A AU2005274788 A AU 2005274788A AU 2005274788 A1 AU2005274788 A1 AU 2005274788A1
Authority
AU
Australia
Prior art keywords
subject
biomarker
expression
protein
neurodegenerative disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2005274788A
Other languages
English (en)
Inventor
Paul D. Coleman
Christopher Cox
Howard J. Federoff
Roger M. Kurlan
Rebekah Loy
Kathleen Maguire-Zeiss
Fredrick Marshall
Timothy R. Mhyre
Pierre Tariot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Rochester
Original Assignee
University of Rochester
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Rochester filed Critical University of Rochester
Publication of AU2005274788A1 publication Critical patent/AU2005274788A1/en
Abandoned legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56972White blood cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2814Dementia; Cognitive disorders
    • G01N2800/2821Alzheimer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2835Movement disorders, e.g. Parkinson, Huntington, Tourette
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2005274788A 2004-07-19 2005-07-19 Biomarkers of neurodegenerative disease Abandoned AU2005274788A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58931804P 2004-07-19 2004-07-19
US60/589,318 2004-07-19
PCT/US2005/025491 WO2006020269A2 (en) 2004-07-19 2005-07-19 Biomarkers of neurodegenerative disease

Publications (1)

Publication Number Publication Date
AU2005274788A1 true AU2005274788A1 (en) 2006-02-23

Family

ID=35907991

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005274788A Abandoned AU2005274788A1 (en) 2004-07-19 2005-07-19 Biomarkers of neurodegenerative disease

Country Status (6)

Country Link
EP (1) EP1797425A2 (zh)
JP (1) JP2008506415A (zh)
CN (1) CN101137903A (zh)
AU (1) AU2005274788A1 (zh)
CA (1) CA2574727A1 (zh)
WO (1) WO2006020269A2 (zh)

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* Cited by examiner, † Cited by third party
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KR20180001596A (ko) 2008-01-18 2018-01-04 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 체액 내에서 질병 또는 병태의 시그너쳐의 검출 방법
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WO2010030365A2 (en) 2008-09-12 2010-03-18 Cornell Research Foundation, Inc. Wmc Thyroid tumors identified
US20100304371A1 (en) * 2009-05-29 2010-12-02 Ana Maria Zarraga Compositions and methods for detecting mycobacteria
CN101961240B (zh) * 2009-07-24 2012-05-30 瑞鼎科技股份有限公司 生物传感器、探针、感测设备以及生物传感器制作方法
JP5823299B2 (ja) * 2010-01-14 2015-11-25 学校法人 埼玉医科大学 糖代謝、脂質代謝、肥満、及び寿命の少なくともいずれかを制御する作用を有する物質のインビトロでのスクリーニング方法
WO2012012694A2 (en) 2010-07-23 2012-01-26 President And Fellows Of Harvard College Methods of detecting autoimmune or immune-related diseases or conditions
AU2011280936A1 (en) 2010-07-23 2013-02-28 President And Fellows Of Harvard College Methods of detecting prenatal or pregnancy-related diseases or conditions
EP4303584A3 (en) 2010-07-23 2024-04-03 President and Fellows of Harvard College Methods for detecting signatures of disease or conditions in bodily fluids
SG10201505724SA (en) 2010-07-23 2015-09-29 Harvard College Methods of detecting diseases or conditions using phagocytic cells
GB201021509D0 (en) * 2010-12-20 2011-02-02 Reactivlab Ltd Assay method
CN102135544A (zh) * 2011-02-23 2011-07-27 中国人民解放军第二军医大学 cyclin G1蛋白的应用
US20120232016A1 (en) * 2011-03-08 2012-09-13 Coleman Paul D Method and system to detect and diagnose alzheimer's disease
WO2012149607A1 (en) * 2011-05-03 2012-11-08 Commonwealth Scientific And Industrial Research Organisation Method for detection of a neurological disease
EP2825886A4 (en) * 2012-03-14 2015-11-18 Stephen Marx MEANS AND METHODS FOR THE DIAGNOSIS AND THERAPEUTICS OF DISEASES
CN102707065A (zh) * 2012-03-23 2012-10-03 常熟市虞山绿茶有限公司 Prohibitin蛋白抗体在制备诊断老年性痴呆的试剂盒中的应用
KR20150010793A (ko) 2012-05-25 2015-01-28 버그 엘엘씨 열 충격 단백질 (hsp) 90-베타의 조절에 의한 대사 증후군의 치료 방법들
KR20150035818A (ko) 2012-06-15 2015-04-07 해리 스타일리 순환 병든 세포를 사용하여 질환 또는 병태를 검출하는 방법
MX2014015425A (es) 2012-06-15 2015-07-14 Harry Stylli Metodos para detectar enfermedades o condiciones.
GB201212084D0 (en) * 2012-07-06 2012-08-22 Randox Lab Ltd Tropomyosin isoforms related to alzheimers disease and mild cognitive impairment
EP2965086A4 (en) 2013-03-09 2017-02-08 Harry Stylli Methods of detecting prostate cancer
EP2965077B1 (en) 2013-03-09 2022-07-13 Harry Stylli Methods of detecting cancer
US9588129B2 (en) * 2013-03-15 2017-03-07 Amira Medical Technologies Inc. Methods for analyzing blood to detect diseases associated with abnormal protein aggregation
KR101497797B1 (ko) * 2013-03-19 2015-03-04 이화여자대학교 산학협력단 열충격단백질(Heat shock protein) 및 LRPPRC 단백질 신호전달을 이용한 파킨슨병 치료제 스크리닝 방법
EP3751283A3 (en) 2013-07-11 2021-03-24 University of North Texas Health Science Center at Fort Worth Blood-based screen for detecting neurological diseases in primary care settings
CN103487587B (zh) * 2013-09-16 2017-02-01 承功(厦门)生物科技有限公司 老年痴呆症体外检测用检测板及其检测试剂盒
WO2015081166A1 (en) 2013-11-26 2015-06-04 University Of North Texas Health Science Center At Fort Worth Personalized medicine approach for treating cognitive loss
WO2015188198A2 (en) 2014-06-06 2015-12-10 Berg Llc Methods of treating a metabolic syndrome by modulating heat shock protein (hsp) 90-beta
WO2016040843A1 (en) 2014-09-11 2016-03-17 Harry Stylli Methods of detecting prostate cancer
US10282875B2 (en) 2015-12-11 2019-05-07 International Business Machines Corporation Graph-based analysis for bio-signal event sensing
CN105548574A (zh) * 2016-02-02 2016-05-04 潍坊三维生物工程集团有限公司 检测c1抑制剂含量的试剂盒、方法及用途
WO2017193115A1 (en) * 2016-05-06 2017-11-09 Nanosomix, Inc. Synaptic protein biomarkers and differential diagnosis of alzheimer's disease and other neurodegenerative disorders
US20210283097A1 (en) * 2016-07-26 2021-09-16 Ausio Pharmaceuticals, Llc Methods of diagnosing and treating alzheimer's disease with s-equol
US10914748B2 (en) 2016-09-08 2021-02-09 UNIVERSITé LAVAL Erythrocyte-derived extracellular vesicles as a biomarker for clinically assessing Parkinson's disease
EP3312611B1 (en) * 2016-10-21 2020-02-26 Dr. Power Stem Biomedical Research Inc., Ltd. Method for diagnosis of alzheimer's disease
US11193933B2 (en) 2016-10-26 2021-12-07 Dr. Power Stem Biomedical Research Inc., Ltd. Measuring GAPDH protein for diagnosis and treatment of alzheimer's disease
TWI622771B (zh) * 2016-10-27 2018-05-01 百威研發股份有限公司 診斷阿茲海默症方法
WO2018081878A1 (en) * 2016-11-07 2018-05-11 Macquarie University Modulation of protein accumulation and uses therefor
US10345302B2 (en) * 2017-02-19 2019-07-09 Sheng-He Huang Circulating astrocytes and MFSD2A as biomarkers
KR102633621B1 (ko) 2017-09-01 2024-02-05 벤 바이오사이언시스 코포레이션 진단 및 치료 모니터링용 바이오마커로서의 당펩티드의 식별 및 용도
EP4048320A4 (en) * 2019-10-21 2023-11-22 Macquarie University MODULATION OF CELL VIABILITY
CN113801929A (zh) * 2020-06-11 2021-12-17 香港科技大学 用于鉴定能够治疗阿尔茨海默病的药物的方法
CN111986730A (zh) * 2020-07-27 2020-11-24 中国科学院计算技术研究所苏州智能计算产业技术研究院 一种预测siRNA沉默效率的方法
WO2023049830A1 (en) * 2021-09-24 2023-03-30 Wake Forest University Health Sciences Detecting and treating conditions associated with neuronal senescence

Also Published As

Publication number Publication date
CN101137903A (zh) 2008-03-05
WO2006020269A2 (en) 2006-02-23
CA2574727A1 (en) 2006-02-23
JP2008506415A (ja) 2008-03-06
EP1797425A2 (en) 2007-06-20
WO2006020269A3 (en) 2007-04-05

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Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application