AU2005245004B2 - Sensitization to another anticancer therapy and/or amelioration of a side effect of another anticancer therapy by treatment with a GST-activated anticancer compound - Google Patents

Sensitization to another anticancer therapy and/or amelioration of a side effect of another anticancer therapy by treatment with a GST-activated anticancer compound Download PDF

Info

Publication number
AU2005245004B2
AU2005245004B2 AU2005245004A AU2005245004A AU2005245004B2 AU 2005245004 B2 AU2005245004 B2 AU 2005245004B2 AU 2005245004 A AU2005245004 A AU 2005245004A AU 2005245004 A AU2005245004 A AU 2005245004A AU 2005245004 B2 AU2005245004 B2 AU 2005245004B2
Authority
AU
Australia
Prior art keywords
therapy
another anticancer
anticancer therapy
canfosfamide
anticancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2005245004A
Other languages
English (en)
Other versions
AU2005245004A1 (en
Inventor
Gail L. Brown
James G. Keck
Michael M. Wick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Telik Inc
Original Assignee
Telik Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Telik Inc filed Critical Telik Inc
Publication of AU2005245004A1 publication Critical patent/AU2005245004A1/en
Application granted granted Critical
Publication of AU2005245004B2 publication Critical patent/AU2005245004B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/475Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2005245004A 2004-05-20 2005-05-19 Sensitization to another anticancer therapy and/or amelioration of a side effect of another anticancer therapy by treatment with a GST-activated anticancer compound Ceased AU2005245004B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57279004P 2004-05-20 2004-05-20
US60/572,790 2004-05-20
PCT/US2005/017960 WO2005112973A1 (en) 2004-05-20 2005-05-19 Sensitization to another anticancer therapy and/or amelioration of a side effect of another anticancer therapy by treatment with a gst-activated anticancer compound

Publications (2)

Publication Number Publication Date
AU2005245004A1 AU2005245004A1 (en) 2005-12-01
AU2005245004B2 true AU2005245004B2 (en) 2011-08-04

Family

ID=34970551

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005245004A Ceased AU2005245004B2 (en) 2004-05-20 2005-05-19 Sensitization to another anticancer therapy and/or amelioration of a side effect of another anticancer therapy by treatment with a GST-activated anticancer compound

Country Status (12)

Country Link
US (2) US20050261202A1 (enExample)
EP (1) EP1755632A1 (enExample)
JP (1) JP2007538105A (enExample)
KR (1) KR101174685B1 (enExample)
CN (1) CN1953762B (enExample)
AR (1) AR048971A1 (enExample)
AU (1) AU2005245004B2 (enExample)
BR (1) BRPI0511296A (enExample)
CA (1) CA2566850A1 (enExample)
MX (1) MXPA06013375A (enExample)
TW (1) TW200538149A (enExample)
WO (1) WO2005112973A1 (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0011903D0 (en) * 2000-05-18 2000-07-05 Astrazeneca Ab Combination chemotherapy
TWI323662B (en) * 2002-11-15 2010-04-21 Telik Inc Combination cancer therapy with a gst-activated anticancer compound and another anticancer therapy
TW200538149A (en) 2004-05-20 2005-12-01 Telik Inc Sensitization to another anticancer therapy and/or amelioration of a side effect of another anticancer therapy by treatment with a GST-activated anticancer compound
CU23511B6 (es) * 2006-02-28 2010-04-13 Biorec B V Combinación farmacéutica para el tratamiento y/o quimiosensibilización de tumores refractarios a drogas anticancerígenas
ES2293834B1 (es) 2006-07-20 2009-02-16 Consejo Superior Investig. Cientificas Compuesto con actividad inhibidora de las interacciones ubc13-uev, composiciones farmaceuticas que lo comprenden y sus aplicaciones terapeuticas.
US8168661B2 (en) 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8173686B2 (en) 2006-11-06 2012-05-08 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8168662B1 (en) 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8178564B2 (en) * 2006-11-06 2012-05-15 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
EP2091914A4 (en) * 2006-11-08 2010-12-29 Chongxi Yu TRANSDERMAL ADMINISTRATION SYSTEMS FOR PEPTIDES AND RELATED CONNECTIONS
US20110033528A1 (en) * 2009-08-05 2011-02-10 Poniard Pharmaceuticals, Inc. Stabilized picoplatin oral dosage form
BRPI0809937A2 (pt) * 2007-04-14 2014-09-23 Southern Res Inst Métodos de potencialização de tratamento de radioterapia, de intensificação da radiossensibilidade e de diminuição da proliferação de população de células e de tratamento do crescimento de tumor
TW200916094A (en) * 2007-06-27 2009-04-16 Poniard Pharmaceuticals Inc Stabilized picoplatin dosage form
US20100260832A1 (en) * 2007-06-27 2010-10-14 Poniard Pharmaceuticals, Inc. Combination therapy for ovarian cancer
US20100310661A1 (en) * 2007-07-16 2010-12-09 Poniard Pharmaceuticals, Inc. Oral formulations for picoplatin
CA2704395A1 (en) * 2007-11-02 2009-05-14 Ziopharm Oncology, Inc. Combination therapy with organic arsenicals
ES2332557B1 (es) 2007-12-04 2011-02-02 Universidad Autonoma De Madrid Huella genomica para el pronostico de la evolucion de adenocarcinoma colorectal.
ES2332167B1 (es) 2007-12-04 2010-10-25 Universidad Autonoma De Madrid Empleo de trefoil factor-family 3 (tff3) en el pronostico de sujetos diagnosticados con cancer colorectal.
CN102006875A (zh) * 2008-02-08 2011-04-06 帕纳德制药公司 吡铂和贝伐单抗治疗结直肠癌的用途
ES2476602T3 (es) * 2008-03-14 2014-07-15 Bionumerik Pharmaceuticals, Inc. Composiciones y métodos quimioprotectores
ES2338843B1 (es) 2008-07-02 2011-01-24 Centro De Investigaciones Energeticas, Medioambientales Y Tecnologicas Huella genomica de cancer de mama.
EP2169078A1 (en) 2008-09-26 2010-03-31 Fundacion Gaiker Methods and kits for the diagnosis and the staging of colorectal cancer
BRPI1011439B8 (pt) 2009-05-08 2021-05-25 Yu Chongxi composição de alta penetração, composição farmacêutica, sistemas de aplicação terapêutico transdérmico e uso da referida composição
JP5806210B2 (ja) * 2009-06-05 2015-11-10 ティーエーユー・セラピューティクス・エルエルシー 癌または前癌状態を治療するための組み合わせ方法
MX360640B (es) 2010-03-01 2018-11-09 Tau Therapeutics Llc Star Diagnosis e imagenologia de cancer.
US20120251496A1 (en) * 2011-03-31 2012-10-04 Telik, Inc. Ezatiostat for treating multiple myeloma
US20120288554A1 (en) * 2011-05-12 2012-11-15 Telik, Inc. Canfosfamide monotherapy for treating multiple myeloma
WO2013092960A1 (en) 2011-12-22 2013-06-27 Fundacion Gaiker Methods and kits for the diagnosis of colorectal cancer
JP6280546B2 (ja) 2012-06-26 2018-02-14 デル マー ファーマシューティカルズ ジアンヒドロガラクチトール、ジアセチルジアンヒドロガラクチトール、ジブロモズルシトール、又はこれらの類似体若しくは誘導体を用いた、遺伝子多型又はahi1の調節不全若しくは変異を有する患者におけるチロシンキナーゼインヒビター抵抗性悪性腫瘍を処置するための方法
JP6340162B2 (ja) 2012-12-20 2018-06-06 日東電工株式会社 アポトーシス誘導剤
EP2983674A4 (en) 2013-04-08 2017-05-10 Dennis M. Brown Therapeutic benefit of suboptimally administered chemical compounds
CN106573062B (zh) 2014-06-17 2020-08-25 日东电工株式会社 细胞凋亡诱导剂

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004045593A2 (en) * 2002-11-15 2004-06-03 Telik, Inc. Combination cancer therapy with a gst-activated anticancer compound and another anticancer therapy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5556942A (en) * 1991-04-29 1996-09-17 Terrapin Technologies, Inc. Glutathione S-transferase-activated compounds
US5767147A (en) * 1995-04-21 1998-06-16 The Regents Of The University Of California Inhibition of glutathione transferase by haloenol lactones
WO1996040205A1 (en) 1995-06-07 1996-12-19 Terrapin Technologies, Inc. Metabolic effects of certain glutathione analogs
US5880097A (en) * 1996-01-04 1999-03-09 Terrapin Techologies, Inc. Tethered prodrugs
US6281223B1 (en) * 1999-04-13 2001-08-28 Supergen, Inc. Radioenhanced camptothecin derivative cancer treatments
TW200538149A (en) 2004-05-20 2005-12-01 Telik Inc Sensitization to another anticancer therapy and/or amelioration of a side effect of another anticancer therapy by treatment with a GST-activated anticancer compound

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004045593A2 (en) * 2002-11-15 2004-06-03 Telik, Inc. Combination cancer therapy with a gst-activated anticancer compound and another anticancer therapy

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
European Journal Of Cancer, Pergamon Press, Oxford, GB, vol. 38, November 2002, page S35 *

Also Published As

Publication number Publication date
US8207121B2 (en) 2012-06-26
AR048971A1 (es) 2006-06-14
CN1953762B (zh) 2012-04-25
TW200538149A (en) 2005-12-01
JP2007538105A (ja) 2007-12-27
KR101174685B1 (ko) 2012-08-16
WO2005112973A1 (en) 2005-12-01
US20080166428A1 (en) 2008-07-10
BRPI0511296A (pt) 2007-12-04
AU2005245004A1 (en) 2005-12-01
MXPA06013375A (es) 2007-03-01
CN1953762A (zh) 2007-04-25
EP1755632A1 (en) 2007-02-28
CA2566850A1 (en) 2005-12-01
KR20070012542A (ko) 2007-01-25
US20050261202A1 (en) 2005-11-24

Similar Documents

Publication Publication Date Title
AU2005245004B2 (en) Sensitization to another anticancer therapy and/or amelioration of a side effect of another anticancer therapy by treatment with a GST-activated anticancer compound
US20080159980A1 (en) Combination cancer therapy with a GST-activated anticancer compound and another anticancer therapy
US7485626B2 (en) Combinations of enzyme inhibitor-containing preparations and the use thereof
JP4991107B2 (ja) コンブレタスタチンおよび抗癌剤からなる組成物
KR20000016749A (ko) Naaladase 억제제로서 사용가능한 특정의 포스피닐 유도체
JP2006508980A5 (enExample)
Casazza et al. Paclitaxel (Taxol®) mechanisms of resistance
EP0770091B1 (en) Compounds for reversing drug resistance
KR20030096222A (ko) 디스타마이신 유도체를 포함하는 항종양 요법
Schilder et al. New therapies for ovarian cancer
JPH11507370A (ja) ウレタン媒介gst特異的分子放出システム
AU2005319579B2 (en) Process for and intermediates in the preparation of canfosfamide and its salts, pharmaceutical compositions containing some intermediates, and their use as anticancer agents
KR20210087972A (ko) 암 치료를 위한 암 치료제와 병용된 IRE1α 억제제

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired