AU2005240849B2 - Ester linked macrolides useful for the treatment of microbial infections - Google Patents

Ester linked macrolides useful for the treatment of microbial infections Download PDF

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Publication number
AU2005240849B2
AU2005240849B2 AU2005240849A AU2005240849A AU2005240849B2 AU 2005240849 B2 AU2005240849 B2 AU 2005240849B2 AU 2005240849 A AU2005240849 A AU 2005240849A AU 2005240849 A AU2005240849 A AU 2005240849A AU 2005240849 B2 AU2005240849 B2 AU 2005240849B2
Authority
AU
Australia
Prior art keywords
ethoxy
oxo
dihydro
carboxy
propionyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2005240849A
Other languages
English (en)
Other versions
AU2005240849A1 (en
Inventor
Sulejman Alihodzic
Samra Kapic
Maja Matanovic
Stjepan Mutak
Ivana Palej
Drazen Pavlovic
Vlado Stimac
Adrijana Zupan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fidelta doo
Original Assignee
GlaxoSmithKline Istrazivacki Centar Zagreb doo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GlaxoSmithKline Istrazivacki Centar Zagreb doo filed Critical GlaxoSmithKline Istrazivacki Centar Zagreb doo
Publication of AU2005240849A1 publication Critical patent/AU2005240849A1/en
Application granted granted Critical
Publication of AU2005240849B2 publication Critical patent/AU2005240849B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AU2005240849A 2004-05-06 2005-05-02 Ester linked macrolides useful for the treatment of microbial infections Ceased AU2005240849B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US56940204P 2004-05-06 2004-05-06
US60/569,402 2004-05-06
US58111804P 2004-06-18 2004-06-18
US60/581,118 2004-06-18
PCT/IB2005/001186 WO2005108412A1 (en) 2004-05-06 2005-05-02 Ester linked macrolides useful for the treatment of microbial infections

Publications (2)

Publication Number Publication Date
AU2005240849A1 AU2005240849A1 (en) 2005-11-17
AU2005240849B2 true AU2005240849B2 (en) 2008-10-23

Family

ID=34967616

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005240849A Ceased AU2005240849B2 (en) 2004-05-06 2005-05-02 Ester linked macrolides useful for the treatment of microbial infections

Country Status (16)

Country Link
US (1) US20080255060A1 (https=)
EP (1) EP1756135B1 (https=)
JP (1) JP2007536371A (https=)
AR (1) AR049269A1 (https=)
AT (1) ATE439367T1 (https=)
AU (1) AU2005240849B2 (https=)
BR (1) BRPI0510328A (https=)
CA (1) CA2566085A1 (https=)
DE (1) DE602005015963D1 (https=)
ES (1) ES2331739T3 (https=)
IL (1) IL178876A0 (https=)
MA (1) MA28640B1 (https=)
MX (1) MXPA06012923A (https=)
NO (1) NO20065662L (https=)
RU (1) RU2006143051A (https=)
WO (1) WO2005108412A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2552682T3 (es) 2003-03-10 2015-12-01 Merck Sharp & Dohme Corp. Agentes antibacterianos novedosos
JP2008540503A (ja) 2005-05-10 2008-11-20 グラクソスミスクライン・イストラジヴァッキ・センタル・ザグレブ・ドルズバ・ゼー・オメイェノ・オドゴヴォルノスティオ 細菌感染症の処置に有用なエーテル結合マクロライド
KR101120483B1 (ko) * 2006-12-05 2012-02-29 브리스톨-마이어즈 스퀴브 컴페니 모틸라이드 다형체
CN105732745A (zh) 2007-10-25 2016-07-06 森普拉制药公司 大环内酯类抗菌剂的制备方法
AU2009308182B2 (en) 2008-10-24 2016-05-19 Cempra Pharmaceuticals, Inc. Biodefenses using triazole-containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
US9480679B2 (en) 2009-09-10 2016-11-01 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and MAC diseases
CN105198944B (zh) 2010-05-20 2018-06-01 森普拉制药公司 制备大环内酯和酮内酯及其中间体的方法
EP2613630A4 (en) 2010-09-10 2014-01-15 Cempra Pharmaceuticals Inc HYDROGEN BOND FOR THE PREPARATION OF FLUOROCHETOLIDES FOR THE TREATMENT OF DISEASES
MX2014011537A (es) 2012-03-27 2015-02-10 Cempra Pharmaceuticals Inc Formulaciones parenterales para la administracion de antibioticos macrolidos.
HK1217665A1 (zh) 2013-03-14 2017-01-20 森普拉制药公司 用於治療呼吸道疾病的方法及其製劑
RU2015138797A (ru) 2013-03-15 2017-04-24 Семпра Фармасьютикалс, Инк. Конвергентные способы получения макролидных антибактериальных агентов
GB201608236D0 (en) 2016-05-11 2016-06-22 Fidelta D O O Seco macrolide compounds

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003042228A1 (en) * 2001-11-14 2003-05-22 Glaxo Group Limited Macrolides
WO2004101585A1 (en) * 2003-05-13 2004-11-25 Glaxo Group Limited Macrolides substituded at the 4'-position

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0225384D0 (en) * 2002-10-31 2002-12-11 Glaxo Group Ltd Novel compounds
SI1628989T1 (sl) * 2003-05-13 2007-06-30 Glaxo Group Ltd Nove cikliäśne spojine s 14 in 15 obroäśnimi äśleni
GB0310979D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
JP2008540503A (ja) * 2005-05-10 2008-11-20 グラクソスミスクライン・イストラジヴァッキ・センタル・ザグレブ・ドルズバ・ゼー・オメイェノ・オドゴヴォルノスティオ 細菌感染症の処置に有用なエーテル結合マクロライド

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003042228A1 (en) * 2001-11-14 2003-05-22 Glaxo Group Limited Macrolides
WO2004101585A1 (en) * 2003-05-13 2004-11-25 Glaxo Group Limited Macrolides substituded at the 4'-position

Also Published As

Publication number Publication date
NO20065662L (no) 2007-01-16
EP1756135B1 (en) 2009-08-12
IL178876A0 (en) 2007-03-08
AU2005240849A1 (en) 2005-11-17
EP1756135A1 (en) 2007-02-28
ATE439367T1 (de) 2009-08-15
BRPI0510328A (pt) 2007-10-23
US20080255060A1 (en) 2008-10-16
JP2007536371A (ja) 2007-12-13
CA2566085A1 (en) 2005-11-17
MA28640B1 (fr) 2007-06-01
AR049269A1 (es) 2006-07-12
ES2331739T3 (es) 2010-01-14
DE602005015963D1 (de) 2009-09-24
WO2005108412A1 (en) 2005-11-17
RU2006143051A (ru) 2008-06-20
MXPA06012923A (es) 2007-07-18

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired