ATE439367T1 - Estergebundene makrolide, die sich für die behandlung von mikrobiellen infektionen eignen - Google Patents

Estergebundene makrolide, die sich für die behandlung von mikrobiellen infektionen eignen

Info

Publication number
ATE439367T1
ATE439367T1 AT05739739T AT05739739T ATE439367T1 AT E439367 T1 ATE439367 T1 AT E439367T1 AT 05739739 T AT05739739 T AT 05739739T AT 05739739 T AT05739739 T AT 05739739T AT E439367 T1 ATE439367 T1 AT E439367T1
Authority
AT
Austria
Prior art keywords
treatment
microbial infections
ester bonded
macrolides
macrolides suitable
Prior art date
Application number
AT05739739T
Other languages
German (de)
English (en)
Inventor
Sulejman Alihodzic
Stjepan Mutak
Drazen Pavlovic
Ivana Palej
Vlado Stimac
Samra Kapic
Adrijana Vinter
Skugor Maja Matanovic
Original Assignee
Glaxosmithkline Zagreb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Zagreb filed Critical Glaxosmithkline Zagreb
Application granted granted Critical
Publication of ATE439367T1 publication Critical patent/ATE439367T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT05739739T 2004-05-06 2005-05-02 Estergebundene makrolide, die sich für die behandlung von mikrobiellen infektionen eignen ATE439367T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56940204P 2004-05-06 2004-05-06
US58111804P 2004-06-18 2004-06-18
PCT/IB2005/001186 WO2005108412A1 (en) 2004-05-06 2005-05-02 Ester linked macrolides useful for the treatment of microbial infections

Publications (1)

Publication Number Publication Date
ATE439367T1 true ATE439367T1 (de) 2009-08-15

Family

ID=34967616

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05739739T ATE439367T1 (de) 2004-05-06 2005-05-02 Estergebundene makrolide, die sich für die behandlung von mikrobiellen infektionen eignen

Country Status (16)

Country Link
US (1) US20080255060A1 (https=)
EP (1) EP1756135B1 (https=)
JP (1) JP2007536371A (https=)
AR (1) AR049269A1 (https=)
AT (1) ATE439367T1 (https=)
AU (1) AU2005240849B2 (https=)
BR (1) BRPI0510328A (https=)
CA (1) CA2566085A1 (https=)
DE (1) DE602005015963D1 (https=)
ES (1) ES2331739T3 (https=)
IL (1) IL178876A0 (https=)
MA (1) MA28640B1 (https=)
MX (1) MXPA06012923A (https=)
NO (1) NO20065662L (https=)
RU (1) RU2006143051A (https=)
WO (1) WO2005108412A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2552682T3 (es) 2003-03-10 2015-12-01 Merck Sharp & Dohme Corp. Agentes antibacterianos novedosos
JP2008540503A (ja) 2005-05-10 2008-11-20 グラクソスミスクライン・イストラジヴァッキ・センタル・ザグレブ・ドルズバ・ゼー・オメイェノ・オドゴヴォルノスティオ 細菌感染症の処置に有用なエーテル結合マクロライド
KR101120483B1 (ko) * 2006-12-05 2012-02-29 브리스톨-마이어즈 스퀴브 컴페니 모틸라이드 다형체
CN105732745A (zh) 2007-10-25 2016-07-06 森普拉制药公司 大环内酯类抗菌剂的制备方法
AU2009308182B2 (en) 2008-10-24 2016-05-19 Cempra Pharmaceuticals, Inc. Biodefenses using triazole-containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
US9480679B2 (en) 2009-09-10 2016-11-01 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and MAC diseases
CN105198944B (zh) 2010-05-20 2018-06-01 森普拉制药公司 制备大环内酯和酮内酯及其中间体的方法
EP2613630A4 (en) 2010-09-10 2014-01-15 Cempra Pharmaceuticals Inc HYDROGEN BOND FOR THE PREPARATION OF FLUOROCHETOLIDES FOR THE TREATMENT OF DISEASES
MX2014011537A (es) 2012-03-27 2015-02-10 Cempra Pharmaceuticals Inc Formulaciones parenterales para la administracion de antibioticos macrolidos.
HK1217665A1 (zh) 2013-03-14 2017-01-20 森普拉制药公司 用於治療呼吸道疾病的方法及其製劑
RU2015138797A (ru) 2013-03-15 2017-04-24 Семпра Фармасьютикалс, Инк. Конвергентные способы получения макролидных антибактериальных агентов
GB201608236D0 (en) 2016-05-11 2016-06-22 Fidelta D O O Seco macrolide compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0127349D0 (en) * 2001-11-14 2002-01-02 Glaxo Group Ltd Macrolides
GB0225384D0 (en) * 2002-10-31 2002-12-11 Glaxo Group Ltd Novel compounds
GB0310984D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
SI1628989T1 (sl) * 2003-05-13 2007-06-30 Glaxo Group Ltd Nove cikliäśne spojine s 14 in 15 obroäśnimi äśleni
GB0310979D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
JP2008540503A (ja) * 2005-05-10 2008-11-20 グラクソスミスクライン・イストラジヴァッキ・センタル・ザグレブ・ドルズバ・ゼー・オメイェノ・オドゴヴォルノスティオ 細菌感染症の処置に有用なエーテル結合マクロライド

Also Published As

Publication number Publication date
NO20065662L (no) 2007-01-16
EP1756135B1 (en) 2009-08-12
IL178876A0 (en) 2007-03-08
AU2005240849A1 (en) 2005-11-17
EP1756135A1 (en) 2007-02-28
BRPI0510328A (pt) 2007-10-23
US20080255060A1 (en) 2008-10-16
JP2007536371A (ja) 2007-12-13
CA2566085A1 (en) 2005-11-17
MA28640B1 (fr) 2007-06-01
AR049269A1 (es) 2006-07-12
ES2331739T3 (es) 2010-01-14
DE602005015963D1 (de) 2009-09-24
WO2005108412A1 (en) 2005-11-17
AU2005240849B2 (en) 2008-10-23
RU2006143051A (ru) 2008-06-20
MXPA06012923A (es) 2007-07-18

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