DE602005015963D1 - Estergebundene makrolide, die sich für die behandlung von mikrobiellen infektionen eignen - Google Patents

Estergebundene makrolide, die sich für die behandlung von mikrobiellen infektionen eignen

Info

Publication number
DE602005015963D1
DE602005015963D1 DE602005015963T DE602005015963T DE602005015963D1 DE 602005015963 D1 DE602005015963 D1 DE 602005015963D1 DE 602005015963 T DE602005015963 T DE 602005015963T DE 602005015963 T DE602005015963 T DE 602005015963T DE 602005015963 D1 DE602005015963 D1 DE 602005015963D1
Authority
DE
Germany
Prior art keywords
makrolids
estered
treatment
microbial infections
infections
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602005015963T
Other languages
German (de)
English (en)
Inventor
Sulejman Alihodzic
Stjepan Mutak
Drazen Pavlovic
Ivana Palej
Vlado Stimac
Samra Kapic
Adrijana Vinter
Skugor Maja Matanovic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fidelta doo
Original Assignee
GlaxoSmithKline Istrazivacki Centar Zagreb doo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GlaxoSmithKline Istrazivacki Centar Zagreb doo filed Critical GlaxoSmithKline Istrazivacki Centar Zagreb doo
Publication of DE602005015963D1 publication Critical patent/DE602005015963D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE602005015963T 2004-05-06 2005-05-02 Estergebundene makrolide, die sich für die behandlung von mikrobiellen infektionen eignen Expired - Lifetime DE602005015963D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56940204P 2004-05-06 2004-05-06
US58111804P 2004-06-18 2004-06-18
PCT/IB2005/001186 WO2005108412A1 (en) 2004-05-06 2005-05-02 Ester linked macrolides useful for the treatment of microbial infections

Publications (1)

Publication Number Publication Date
DE602005015963D1 true DE602005015963D1 (de) 2009-09-24

Family

ID=34967616

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005015963T Expired - Lifetime DE602005015963D1 (de) 2004-05-06 2005-05-02 Estergebundene makrolide, die sich für die behandlung von mikrobiellen infektionen eignen

Country Status (16)

Country Link
US (1) US20080255060A1 (https=)
EP (1) EP1756135B1 (https=)
JP (1) JP2007536371A (https=)
AR (1) AR049269A1 (https=)
AT (1) ATE439367T1 (https=)
AU (1) AU2005240849B2 (https=)
BR (1) BRPI0510328A (https=)
CA (1) CA2566085A1 (https=)
DE (1) DE602005015963D1 (https=)
ES (1) ES2331739T3 (https=)
IL (1) IL178876A0 (https=)
MA (1) MA28640B1 (https=)
MX (1) MXPA06012923A (https=)
NO (1) NO20065662L (https=)
RU (1) RU2006143051A (https=)
WO (1) WO2005108412A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2552682T3 (es) 2003-03-10 2015-12-01 Merck Sharp & Dohme Corp. Agentes antibacterianos novedosos
JP2008540503A (ja) 2005-05-10 2008-11-20 グラクソスミスクライン・イストラジヴァッキ・センタル・ザグレブ・ドルズバ・ゼー・オメイェノ・オドゴヴォルノスティオ 細菌感染症の処置に有用なエーテル結合マクロライド
KR101120483B1 (ko) * 2006-12-05 2012-02-29 브리스톨-마이어즈 스퀴브 컴페니 모틸라이드 다형체
CN105732745A (zh) 2007-10-25 2016-07-06 森普拉制药公司 大环内酯类抗菌剂的制备方法
AU2009308182B2 (en) 2008-10-24 2016-05-19 Cempra Pharmaceuticals, Inc. Biodefenses using triazole-containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
US9480679B2 (en) 2009-09-10 2016-11-01 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and MAC diseases
CN105198944B (zh) 2010-05-20 2018-06-01 森普拉制药公司 制备大环内酯和酮内酯及其中间体的方法
EP2613630A4 (en) 2010-09-10 2014-01-15 Cempra Pharmaceuticals Inc HYDROGEN BOND FOR THE PREPARATION OF FLUOROCHETOLIDES FOR THE TREATMENT OF DISEASES
MX2014011537A (es) 2012-03-27 2015-02-10 Cempra Pharmaceuticals Inc Formulaciones parenterales para la administracion de antibioticos macrolidos.
HK1217665A1 (zh) 2013-03-14 2017-01-20 森普拉制药公司 用於治療呼吸道疾病的方法及其製劑
RU2015138797A (ru) 2013-03-15 2017-04-24 Семпра Фармасьютикалс, Инк. Конвергентные способы получения макролидных антибактериальных агентов
GB201608236D0 (en) 2016-05-11 2016-06-22 Fidelta D O O Seco macrolide compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0127349D0 (en) * 2001-11-14 2002-01-02 Glaxo Group Ltd Macrolides
GB0225384D0 (en) * 2002-10-31 2002-12-11 Glaxo Group Ltd Novel compounds
GB0310984D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
SI1628989T1 (sl) * 2003-05-13 2007-06-30 Glaxo Group Ltd Nove cikliäśne spojine s 14 in 15 obroäśnimi äśleni
GB0310979D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
JP2008540503A (ja) * 2005-05-10 2008-11-20 グラクソスミスクライン・イストラジヴァッキ・センタル・ザグレブ・ドルズバ・ゼー・オメイェノ・オドゴヴォルノスティオ 細菌感染症の処置に有用なエーテル結合マクロライド

Also Published As

Publication number Publication date
NO20065662L (no) 2007-01-16
EP1756135B1 (en) 2009-08-12
IL178876A0 (en) 2007-03-08
AU2005240849A1 (en) 2005-11-17
EP1756135A1 (en) 2007-02-28
ATE439367T1 (de) 2009-08-15
BRPI0510328A (pt) 2007-10-23
US20080255060A1 (en) 2008-10-16
JP2007536371A (ja) 2007-12-13
CA2566085A1 (en) 2005-11-17
MA28640B1 (fr) 2007-06-01
AR049269A1 (es) 2006-07-12
ES2331739T3 (es) 2010-01-14
WO2005108412A1 (en) 2005-11-17
AU2005240849B2 (en) 2008-10-23
RU2006143051A (ru) 2008-06-20
MXPA06012923A (es) 2007-07-18

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