AU2005229437A1 - Filamentous fungal mutants with improved homologous recombination efficiency - Google Patents

Filamentous fungal mutants with improved homologous recombination efficiency Download PDF

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Publication number
AU2005229437A1
AU2005229437A1 AU2005229437A AU2005229437A AU2005229437A1 AU 2005229437 A1 AU2005229437 A1 AU 2005229437A1 AU 2005229437 A AU2005229437 A AU 2005229437A AU 2005229437 A AU2005229437 A AU 2005229437A AU 2005229437 A1 AU2005229437 A1 AU 2005229437A1
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gene
nhr
mutant
dna
filamentous fungus
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Abandoned
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AU2005229437A
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Inventor
Van Den Marco Alexander Berg
Petrus Jacobus Theodorus Dekker
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DSM IP Assets BV
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DSM IP Assets BV
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Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Publication of AU2005229437A1 publication Critical patent/AU2005229437A1/en
Priority to AU2012211485A priority Critical patent/AU2012211485A1/en
Abandoned legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/38Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Aspergillus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/385Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from Penicillium
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/145Fungal isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90Stable introduction of foreign DNA into chromosome
    • C12N15/902Stable introduction of foreign DNA into chromosome using homologous recombination
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/645Fungi ; Processes using fungi
    • C12R2001/80Penicillium
    • C12R2001/82Penicillium chrysogenum

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Mushroom Cultivation (AREA)
AU2005229437A 2004-04-02 2005-03-31 Filamentous fungal mutants with improved homologous recombination efficiency Abandoned AU2005229437A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2012211485A AU2012211485A1 (en) 2004-04-02 2012-08-10 Filamentous fungal mutants with improved homologous recombination efficiency

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04076057 2004-04-02
EP04076057.1 2004-04-02
PCT/EP2005/051464 WO2005095624A2 (fr) 2004-04-02 2005-03-31 Mutants fongiques filamenteux avec meilleure efficacite de recombinaison homologue

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2012211485A Division AU2012211485A1 (en) 2004-04-02 2012-08-10 Filamentous fungal mutants with improved homologous recombination efficiency

Publications (1)

Publication Number Publication Date
AU2005229437A1 true AU2005229437A1 (en) 2005-10-13

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ID=34966505

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Application Number Title Priority Date Filing Date
AU2005229437A Abandoned AU2005229437A1 (en) 2004-04-02 2005-03-31 Filamentous fungal mutants with improved homologous recombination efficiency

Country Status (12)

Country Link
US (2) US9243043B2 (fr)
EP (3) EP1733040B1 (fr)
JP (2) JP2007530065A (fr)
CN (1) CN101218348B (fr)
AT (1) ATE480632T1 (fr)
AU (1) AU2005229437A1 (fr)
CA (1) CA2559827A1 (fr)
DE (1) DE602005023427D1 (fr)
DK (1) DK1733040T3 (fr)
ES (1) ES2350048T3 (fr)
PL (1) PL1733040T3 (fr)
WO (1) WO2005095624A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109790510A (zh) * 2016-10-04 2019-05-21 丹尼斯科美国公司 在不存在诱导底物下丝状真菌细胞中的蛋白产生

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US20160130589A1 (en) 2016-05-12
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ATE480632T1 (de) 2010-09-15
DE602005023427D1 (de) 2010-10-21
US9657301B2 (en) 2017-05-23
US9243043B2 (en) 2016-01-26
PL1733040T3 (pl) 2011-01-31
DK1733040T3 (da) 2010-11-22
JP2007530065A (ja) 2007-11-01
EP3351637B1 (fr) 2020-06-10
CN101218348A (zh) 2008-07-09
EP3351637A1 (fr) 2018-07-25
EP1733040B1 (fr) 2010-09-08
CN101218348B (zh) 2014-07-30
CA2559827A1 (fr) 2005-10-13
ES2350048T3 (es) 2011-01-17
EP2172557A1 (fr) 2010-04-07
WO2005095624A2 (fr) 2005-10-13
EP1733040A2 (fr) 2006-12-20
JP2011152148A (ja) 2011-08-11
WO2005095624A3 (fr) 2006-02-16

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