AU2004290476A1 - Stable liposome compositions comprising lipophilic amine containing pharmaceutical agents - Google Patents
Stable liposome compositions comprising lipophilic amine containing pharmaceutical agents Download PDFInfo
- Publication number
- AU2004290476A1 AU2004290476A1 AU2004290476A AU2004290476A AU2004290476A1 AU 2004290476 A1 AU2004290476 A1 AU 2004290476A1 AU 2004290476 A AU2004290476 A AU 2004290476A AU 2004290476 A AU2004290476 A AU 2004290476A AU 2004290476 A1 AU2004290476 A1 AU 2004290476A1
- Authority
- AU
- Australia
- Prior art keywords
- composition
- liposome
- stable
- composition according
- sterile
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 238000000034 method Methods 0.000 claims description 90
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- 125000003277 amino group Chemical group 0.000 claims description 34
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- 239000012736 aqueous medium Substances 0.000 claims description 25
- 238000003860 storage Methods 0.000 claims description 25
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- 231100000440 toxicity profile Toxicity 0.000 description 1
- 229960002051 trandolapril Drugs 0.000 description 1
- LLPOLZWFYMWNKH-UHFFFAOYSA-N trans-dihydrocodeinone Natural products C1C(N(CCC234)C)C2CCC(=O)C3OC2=C4C1=CC=C2OC LLPOLZWFYMWNKH-UHFFFAOYSA-N 0.000 description 1
- PHLBKPHSAVXXEF-UHFFFAOYSA-N trazodone Chemical compound ClC1=CC=CC(N2CCN(CCCN3C(N4C=CC=CC4=N3)=O)CC2)=C1 PHLBKPHSAVXXEF-UHFFFAOYSA-N 0.000 description 1
- 229960003991 trazodone Drugs 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- ZEWQUBUPAILYHI-UHFFFAOYSA-N trifluoperazine Chemical compound C1CN(C)CCN1CCCN1C2=CC(C(F)(F)F)=CC=C2SC2=CC=CC=C21 ZEWQUBUPAILYHI-UHFFFAOYSA-N 0.000 description 1
- 229960002324 trifluoperazine Drugs 0.000 description 1
- XSCGXQMFQXDFCW-UHFFFAOYSA-N triflupromazine Chemical compound C1=C(C(F)(F)F)C=C2N(CCCN(C)C)C3=CC=CC=C3SC2=C1 XSCGXQMFQXDFCW-UHFFFAOYSA-N 0.000 description 1
- 229960003904 triflupromazine Drugs 0.000 description 1
- 229960001032 trihexyphenidyl Drugs 0.000 description 1
- FEZBIKUBAYAZIU-UHFFFAOYSA-N trimethobenzamide Chemical compound COC1=C(OC)C(OC)=CC(C(=O)NCC=2C=CC(OCCN(C)C)=CC=2)=C1 FEZBIKUBAYAZIU-UHFFFAOYSA-N 0.000 description 1
- 229960004161 trimethobenzamide Drugs 0.000 description 1
- 238000000825 ultraviolet detection Methods 0.000 description 1
- 229940005605 valeric acid Drugs 0.000 description 1
- 229960001722 verapamil Drugs 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
- ORZHVTYKPFFVMG-UHFFFAOYSA-N xylenol orange Chemical compound OC(=O)CN(CC(O)=O)CC1=C(O)C(C)=CC(C2(C3=CC=CC=C3S(=O)(=O)O2)C=2C=C(CN(CC(O)=O)CC(O)=O)C(O)=C(C)C=2)=C1 ORZHVTYKPFFVMG-UHFFFAOYSA-N 0.000 description 1
- 238000000733 zeta-potential measurement Methods 0.000 description 1
- 229960001360 zolmitriptan Drugs 0.000 description 1
- ULSDMUVEXKOYBU-ZDUSSCGKSA-N zolmitriptan Chemical compound C1=C2C(CCN(C)C)=CNC2=CC=C1C[C@H]1COC(=O)N1 ULSDMUVEXKOYBU-ZDUSSCGKSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52331603P | 2003-11-20 | 2003-11-20 | |
| US60/523,316 | 2003-11-20 | ||
| PCT/CA2004/002002 WO2005048986A1 (en) | 2003-11-20 | 2004-11-22 | Stable liposome compositions comprising lipophilic amine containing pharmaceutical agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2004290476A1 true AU2004290476A1 (en) | 2005-06-02 |
Family
ID=34619598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2004290476A Abandoned AU2004290476A1 (en) | 2003-11-20 | 2004-11-22 | Stable liposome compositions comprising lipophilic amine containing pharmaceutical agents |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20070269502A1 (https=) |
| EP (1) | EP1689364A4 (https=) |
| JP (1) | JP2007511545A (https=) |
| KR (1) | KR20060123341A (https=) |
| CN (2) | CN1893926B (https=) |
| AU (1) | AU2004290476A1 (https=) |
| BR (1) | BRPI0416650A (https=) |
| CA (1) | CA2588012A1 (https=) |
| MX (1) | MXPA06005688A (https=) |
| NO (1) | NO20062877L (https=) |
| RU (1) | RU2369384C2 (https=) |
| WO (1) | WO2005048986A1 (https=) |
| ZA (1) | ZA200604808B (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4599849B2 (ja) * | 2004-02-18 | 2010-12-15 | コニカミノルタエムジー株式会社 | リポソーム含有製剤の製造方法、およびリポソーム含有製剤 |
| US8772359B2 (en) | 2006-11-08 | 2014-07-08 | Cp Kelco U.S., Inc. | Surfactant thickened systems comprising microfibrous cellulose and methods of making same |
| US9045716B2 (en) | 2006-11-08 | 2015-06-02 | Cp Kelco U.S., Inc. | Surfactant thickened systems comprising microfibrous cellulose and methods of making same |
| WO2009107753A1 (ja) | 2008-02-29 | 2009-09-03 | 財団法人 名古屋産業科学研究所 | 後眼部到達用リポソーム及び後眼部疾患用医薬組成物 |
| US9445975B2 (en) | 2008-10-03 | 2016-09-20 | Access Business Group International, Llc | Composition and method for preparing stable unilamellar liposomal suspension |
| CH702736B1 (de) * | 2008-12-31 | 2012-12-14 | Obschestvo S Organichennoi Otvetstvennostju Scient Company Flamena | Phospholipid-Emulsion, die Dihydroquerzetin beinhaltet. |
| EP2585046A4 (en) * | 2010-06-23 | 2013-11-06 | Brightside Innovations Inc | LECITHINTRÄGERVESIKEL AND METHOD FOR THE PRODUCTION THEREOF |
| EP2771341A4 (en) * | 2011-10-28 | 2015-09-23 | Univ Texas | NEW COMPOSITIONS AND METHOD FOR THE TREATMENT OF CANCER |
| JP2015507019A (ja) * | 2012-02-17 | 2015-03-05 | セルシオン コーポレイション | 感熱性ナノ粒子製剤およびその製造方法 |
| JPWO2014017233A1 (ja) * | 2012-07-27 | 2016-07-07 | 住友重機械工業株式会社 | 微生物用活性調節剤及び微生物の活性を調節する方法 |
| RU2529179C1 (ru) * | 2013-04-23 | 2014-09-27 | Общество с ограниченной ответственностью "Уральский центр биофармацевтических технологий" | Стабилизатор липосомальных суспензий и способ его получения |
| AU2016256979B2 (en) | 2015-05-04 | 2021-01-28 | Genfit | Method for preparing transmembrane pH-gradient vesicles |
| EP3416636A4 (en) * | 2016-02-15 | 2019-10-16 | Kemin Industries, Inc. | WATER-SOLUBLE LIPOPHILIC SUBSTANCES |
| WO2019126766A1 (en) * | 2017-12-21 | 2019-06-27 | Taiwan Liposome Co., Ltd. | Sustained-release triptan compositions and method of use the same through subdermal route or the like |
| EP3991722A4 (en) * | 2019-06-28 | 2022-10-05 | Jiangsu Hengrui Medicine Co., Ltd. | LIPID COMPOSITION WITH DELAYED RELEASE AND THEIR PROCESS OF PRODUCTION |
| CN112823009A (zh) * | 2019-08-28 | 2021-05-18 | 上海谷森医药有限公司 | 糠酸氟替卡松脂质体制剂及其制备方法 |
| RU2712079C1 (ru) * | 2019-09-05 | 2020-01-24 | Федеральное государственное бюджетное учреждение науки "Уральский научно-практический центр радиационной медицины Федерального медико-биологического агентства" (ФГБУН УНПЦ РМ ФМБА России) | Липосомальное лекарственное средство для лечения местных радиационных поражений кожи |
| CN113197848B (zh) * | 2021-05-24 | 2023-06-09 | 成都欣捷高新技术开发股份有限公司 | 一种重酒石酸间羟胺药物组合物及其制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0152379A3 (de) * | 1984-02-15 | 1986-10-29 | Ciba-Geigy Ag | Verfahren zur Herstellung von pharmazeutischen Zusammensetzungen enthaltend unilamellare Liposomen |
| AU598958B2 (en) * | 1987-11-12 | 1990-07-05 | Vestar, Inc. | Improved amphotericin b liposome preparation |
| WO1990003808A1 (en) * | 1988-10-07 | 1990-04-19 | The Liposome Company, Inc. | Heat treating liposomes |
| WO1990014105A1 (en) * | 1989-05-15 | 1990-11-29 | The Liposome Company, Inc. | Accumulation of drugs into liposomes by a proton gradient |
| JP3383704B2 (ja) * | 1993-04-02 | 2003-03-04 | わかもと製薬株式会社 | 安定なリポソーム水分散液 |
| US5451408A (en) * | 1994-03-23 | 1995-09-19 | Liposome Pain Management, Ltd. | Pain management with liposome-encapsulated analgesic drugs |
| GB9605915D0 (en) * | 1996-03-21 | 1996-05-22 | Univ Bruxelles | Liposome encapsulated amphiphilic drug compositions |
| GB9708066D0 (en) * | 1997-04-22 | 1997-06-11 | Woolcombers Group Plc | Compositions and their use |
| WO2003075889A1 (en) * | 2002-03-05 | 2003-09-18 | Transave, Inc. | An inhalation system for prevention and treatment of intracellular infections |
-
2004
- 2004-11-22 BR BRPI0416650-7A patent/BRPI0416650A/pt not_active IP Right Cessation
- 2004-11-22 JP JP2006540118A patent/JP2007511545A/ja active Pending
- 2004-11-22 CA CA002588012A patent/CA2588012A1/en not_active Abandoned
- 2004-11-22 CN CN2004800343913A patent/CN1893926B/zh not_active Expired - Fee Related
- 2004-11-22 AU AU2004290476A patent/AU2004290476A1/en not_active Abandoned
- 2004-11-22 KR KR1020067011847A patent/KR20060123341A/ko not_active Ceased
- 2004-11-22 US US10/580,077 patent/US20070269502A1/en not_active Abandoned
- 2004-11-22 CN CN2010101414947A patent/CN101889981A/zh active Pending
- 2004-11-22 EP EP04818742A patent/EP1689364A4/en not_active Withdrawn
- 2004-11-22 MX MXPA06005688A patent/MXPA06005688A/es not_active Application Discontinuation
- 2004-11-22 RU RU2006121554/15A patent/RU2369384C2/ru not_active IP Right Cessation
- 2004-11-22 WO PCT/CA2004/002002 patent/WO2005048986A1/en not_active Ceased
-
2006
- 2006-06-12 ZA ZA200604808A patent/ZA200604808B/xx unknown
- 2006-06-19 NO NO20062877A patent/NO20062877L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20062877L (no) | 2006-08-21 |
| ZA200604808B (en) | 2007-11-28 |
| RU2369384C2 (ru) | 2009-10-10 |
| RU2006121554A (ru) | 2007-12-27 |
| CN101889981A (zh) | 2010-11-24 |
| EP1689364A1 (en) | 2006-08-16 |
| CN1893926B (zh) | 2010-09-08 |
| EP1689364A4 (en) | 2008-10-29 |
| MXPA06005688A (es) | 2006-12-14 |
| US20070269502A1 (en) | 2007-11-22 |
| CN1893926A (zh) | 2007-01-10 |
| BRPI0416650A (pt) | 2007-01-16 |
| WO2005048986A1 (en) | 2005-06-02 |
| CA2588012A1 (en) | 2005-06-02 |
| KR20060123341A (ko) | 2006-12-01 |
| JP2007511545A (ja) | 2007-05-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC1 | Assignment before grant (sect. 113) |
Owner name: YM BIOSCIENCES INC. Free format text: FORMER APPLICANT(S): DELEX THERAPEUTICS INC. |
|
| MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |