NO20062877L - Stabile liposomsammensetninger som omfatter lipofile aminholdige farmasoytiske midler - Google Patents
Stabile liposomsammensetninger som omfatter lipofile aminholdige farmasoytiske midlerInfo
- Publication number
- NO20062877L NO20062877L NO20062877A NO20062877A NO20062877L NO 20062877 L NO20062877 L NO 20062877L NO 20062877 A NO20062877 A NO 20062877A NO 20062877 A NO20062877 A NO 20062877A NO 20062877 L NO20062877 L NO 20062877L
- Authority
- NO
- Norway
- Prior art keywords
- pharmaceutically acceptable
- lipophilic amine
- compositions
- composition
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
Abstract
Stabil liposomsammensetning for levering av et farmasøytisk middel, hvor sammensetningen omfatter: (a) et egnet vandig medium, (b) liposomer dannet av et egnet fosfolipid; (c) minst ett farmasøytisk middel som i det minste delvis er innkapslet i liposomene, og er valgt fra (i) et lipofilt amin og en farmasøytisk akseptabel syre, hvor den farmasøytisk akseptable syren er valgt fra en organisk eller uorganisk syre, og (ii) et farmasøytisk akseptabelt organisk syresalt av et lipofilt amin, og eventuelt en farmasøytisk akseptabel organisk syre; hvor mengden av den farmasøytisk akseptable syren som er tilstede i sammensetningen, er slik at liposomsammensetningens pH-verdi er mindre enn eller omtrent lik pKa-verdien for aminogruppen i det farmasøytisk aktive lipofile aminet. Det er også tilveiebrakt sammensetninger, sett og fremgangsmåter for fremstilling av samme, så vel som fremgangsmåter for ytterligere å bedre stabiliteten på sammensetningene ved autoklavering, foruten fremgangsmåter for å identifisere stabile liposomsammensetninger ifølge den foreliggende oppfinnelsen.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US52331603P | 2003-11-20 | 2003-11-20 | |
PCT/CA2004/002002 WO2005048986A1 (en) | 2003-11-20 | 2004-11-22 | Stable liposome compositions comprising lipophilic amine containing pharmaceutical agents |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20062877L true NO20062877L (no) | 2006-08-21 |
Family
ID=34619598
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20062877A NO20062877L (no) | 2003-11-20 | 2006-06-19 | Stabile liposomsammensetninger som omfatter lipofile aminholdige farmasoytiske midler |
Country Status (13)
Country | Link |
---|---|
US (1) | US20070269502A1 (no) |
EP (1) | EP1689364A4 (no) |
JP (1) | JP2007511545A (no) |
KR (1) | KR20060123341A (no) |
CN (2) | CN1893926B (no) |
AU (1) | AU2004290476A1 (no) |
BR (1) | BRPI0416650A (no) |
CA (1) | CA2588012A1 (no) |
MX (1) | MXPA06005688A (no) |
NO (1) | NO20062877L (no) |
RU (1) | RU2369384C2 (no) |
WO (1) | WO2005048986A1 (no) |
ZA (1) | ZA200604808B (no) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4599849B2 (ja) * | 2004-02-18 | 2010-12-15 | コニカミノルタエムジー株式会社 | リポソーム含有製剤の製造方法、およびリポソーム含有製剤 |
US9045716B2 (en) | 2006-11-08 | 2015-06-02 | Cp Kelco U.S., Inc. | Surfactant thickened systems comprising microfibrous cellulose and methods of making same |
US8772359B2 (en) * | 2006-11-08 | 2014-07-08 | Cp Kelco U.S., Inc. | Surfactant thickened systems comprising microfibrous cellulose and methods of making same |
WO2009107753A1 (ja) * | 2008-02-29 | 2009-09-03 | 財団法人 名古屋産業科学研究所 | 後眼部到達用リポソーム及び後眼部疾患用医薬組成物 |
US9445975B2 (en) | 2008-10-03 | 2016-09-20 | Access Business Group International, Llc | Composition and method for preparing stable unilamellar liposomal suspension |
WO2010077165A1 (en) * | 2008-12-31 | 2010-07-08 | Obschestvo S Ogranichennoi Otvetstvennostju Scientific Company Flamena | Phospholipid emulsion containing dihydroquercetin, and method of producing thereof |
US20110318406A1 (en) * | 2010-06-23 | 2011-12-29 | Eley Crispin G S | Lecithin carrier vesicles and methods of making the same |
EP2771341A4 (en) * | 2011-10-28 | 2015-09-23 | Univ Texas | NEW COMPOSITIONS AND METHOD FOR THE TREATMENT OF CANCER |
CN104203216A (zh) * | 2012-02-17 | 2014-12-10 | 效思因公司 | 热敏纳米颗粒制剂及其制备方法 |
WO2014017233A1 (ja) * | 2012-07-27 | 2014-01-30 | 住友重機械工業株式会社 | 微生物用活性調節剤及び微生物の活性を調節する方法 |
RU2529179C1 (ru) * | 2013-04-23 | 2014-09-27 | Общество с ограниченной ответственностью "Уральский центр биофармацевтических технологий" | Стабилизатор липосомальных суспензий и способ его получения |
AU2016256979B2 (en) | 2015-05-04 | 2021-01-28 | Versantis AG | Method for preparing transmembrane pH-gradient vesicles |
CN108697681B (zh) | 2016-02-15 | 2022-01-25 | 建明(中国)科技有限公司 | 水溶性亲脂性材料 |
EP3727333A1 (en) * | 2017-12-21 | 2020-10-28 | Taiwan Liposome Company Ltd | Sustained-release triptan compositions and method of use the same through subdermal route or the like |
US20220249375A1 (en) * | 2019-06-28 | 2022-08-11 | Jiangsu Hengrui Medicine Co., Ltd. | Sustained-release lipid composition and preparation method therefor |
CN112823009A (zh) * | 2019-08-28 | 2021-05-18 | 上海谷森医药有限公司 | 糠酸氟替卡松脂质体制剂及其制备方法 |
RU2712079C1 (ru) * | 2019-09-05 | 2020-01-24 | Федеральное государственное бюджетное учреждение науки "Уральский научно-практический центр радиационной медицины Федерального медико-биологического агентства" (ФГБУН УНПЦ РМ ФМБА России) | Липосомальное лекарственное средство для лечения местных радиационных поражений кожи |
CN113197848B (zh) * | 2021-05-24 | 2023-06-09 | 成都欣捷高新技术开发股份有限公司 | 一种重酒石酸间羟胺药物组合物及其制备方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0152379A3 (de) * | 1984-02-15 | 1986-10-29 | Ciba-Geigy Ag | Verfahren zur Herstellung von pharmazeutischen Zusammensetzungen enthaltend unilamellare Liposomen |
AU598958B2 (en) * | 1987-11-12 | 1990-07-05 | Vestar, Inc. | Improved amphotericin b liposome preparation |
WO1990003808A1 (en) * | 1988-10-07 | 1990-04-19 | The Liposome Company, Inc. | Heat treating liposomes |
WO1990014105A1 (en) * | 1989-05-15 | 1990-11-29 | The Liposome Company, Inc. | Accumulation of drugs into liposomes by a proton gradient |
JP3383704B2 (ja) * | 1993-04-02 | 2003-03-04 | わかもと製薬株式会社 | 安定なリポソーム水分散液 |
US5451408A (en) * | 1994-03-23 | 1995-09-19 | Liposome Pain Management, Ltd. | Pain management with liposome-encapsulated analgesic drugs |
GB9605915D0 (en) * | 1996-03-21 | 1996-05-22 | Univ Bruxelles | Liposome encapsulated amphiphilic drug compositions |
GB9708066D0 (en) * | 1997-04-22 | 1997-06-11 | Woolcombers Group Plc | Compositions and their use |
AU2003225689B2 (en) * | 2002-03-05 | 2009-03-26 | Transave, Inc. | Methods for entrapment of bioactive agent in a liposome or lipid complex |
-
2004
- 2004-11-22 CN CN2004800343913A patent/CN1893926B/zh not_active Expired - Fee Related
- 2004-11-22 CA CA002588012A patent/CA2588012A1/en not_active Abandoned
- 2004-11-22 KR KR1020067011847A patent/KR20060123341A/ko not_active Application Discontinuation
- 2004-11-22 RU RU2006121554/15A patent/RU2369384C2/ru not_active IP Right Cessation
- 2004-11-22 MX MXPA06005688A patent/MXPA06005688A/es not_active Application Discontinuation
- 2004-11-22 AU AU2004290476A patent/AU2004290476A1/en not_active Abandoned
- 2004-11-22 CN CN2010101414947A patent/CN101889981A/zh active Pending
- 2004-11-22 JP JP2006540118A patent/JP2007511545A/ja active Pending
- 2004-11-22 EP EP04818742A patent/EP1689364A4/en not_active Withdrawn
- 2004-11-22 US US10/580,077 patent/US20070269502A1/en not_active Abandoned
- 2004-11-22 WO PCT/CA2004/002002 patent/WO2005048986A1/en active Application Filing
- 2004-11-22 BR BRPI0416650-7A patent/BRPI0416650A/pt not_active IP Right Cessation
-
2006
- 2006-06-12 ZA ZA200604808A patent/ZA200604808B/xx unknown
- 2006-06-19 NO NO20062877A patent/NO20062877L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU2004290476A1 (en) | 2005-06-02 |
US20070269502A1 (en) | 2007-11-22 |
RU2369384C2 (ru) | 2009-10-10 |
CN101889981A (zh) | 2010-11-24 |
RU2006121554A (ru) | 2007-12-27 |
EP1689364A4 (en) | 2008-10-29 |
MXPA06005688A (es) | 2006-12-14 |
CN1893926A (zh) | 2007-01-10 |
ZA200604808B (en) | 2007-11-28 |
CA2588012A1 (en) | 2005-06-02 |
BRPI0416650A (pt) | 2007-01-16 |
CN1893926B (zh) | 2010-09-08 |
JP2007511545A (ja) | 2007-05-10 |
EP1689364A1 (en) | 2006-08-16 |
KR20060123341A (ko) | 2006-12-01 |
WO2005048986A1 (en) | 2005-06-02 |
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |