AU2003300137A1 - Pharmaceutical formulation with an insoluble active agent for pulmonary administration - Google Patents
Pharmaceutical formulation with an insoluble active agent for pulmonary administration Download PDFInfo
- Publication number
- AU2003300137A1 AU2003300137A1 AU2003300137A AU2003300137A AU2003300137A1 AU 2003300137 A1 AU2003300137 A1 AU 2003300137A1 AU 2003300137 A AU2003300137 A AU 2003300137A AU 2003300137 A AU2003300137 A AU 2003300137A AU 2003300137 A1 AU2003300137 A1 AU 2003300137A1
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- Australia
- Prior art keywords
- pharmaceutical formulation
- particulates
- formulation according
- active agent
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- Prior art date
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- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
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- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43721002P | 2002-12-31 | 2002-12-31 | |
| US60/437,210 | 2002-12-31 | ||
| PCT/US2003/041703 WO2004060351A2 (en) | 2002-12-31 | 2003-12-31 | Pharmaceutical formulation with an insoluble active agent for pulmonary administration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2003300137A1 true AU2003300137A1 (en) | 2004-07-29 |
Family
ID=32713146
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003300137A Abandoned AU2003300137A1 (en) | 2002-12-31 | 2003-12-31 | Pharmaceutical formulation with an insoluble active agent for pulmonary administration |
Country Status (18)
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|---|---|
| US (1) | US20040156792A1 (https=) |
| EP (1) | EP1589947B2 (https=) |
| JP (1) | JP2006513236A (https=) |
| KR (1) | KR20050095838A (https=) |
| CN (1) | CN1741789A (https=) |
| AU (1) | AU2003300137A1 (https=) |
| BR (1) | BR0317810A (https=) |
| CA (1) | CA2511523C (https=) |
| EA (1) | EA200501001A1 (https=) |
| ES (1) | ES2589578T5 (https=) |
| HU (1) | HUP0500846A3 (https=) |
| MX (1) | MXPA05007158A (https=) |
| NO (1) | NO20053076L (https=) |
| PL (1) | PL378270A1 (https=) |
| PT (1) | PT1589947T (https=) |
| TR (1) | TR200502522T2 (https=) |
| WO (1) | WO2004060351A2 (https=) |
| ZA (1) | ZA200505155B (https=) |
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| US8404217B2 (en) | 2000-05-10 | 2013-03-26 | Novartis Ag | Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use |
| US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
| ES2525087T5 (es) | 2000-05-10 | 2018-06-28 | Novartis Ag | Polvos basados en fosfolípidos para administración de fármacos |
| JP2005514393A (ja) * | 2001-12-19 | 2005-05-19 | ネクター セラピューティクス | アミノグリコシドの肺への供給 |
| MXPA05007156A (es) * | 2002-12-31 | 2005-09-21 | Nektar Therapeutics | Formulacion farmaceuticas aerosolizable para terapia para infecciones fungicas. |
| CA2523475C (en) | 2003-05-28 | 2013-02-05 | Nektar Therapeutics | Pharmaceutical formulation comprising a water-insoluble active agent |
| US8513204B2 (en) * | 2004-06-21 | 2013-08-20 | Novartis Ag | Compositions comprising amphotericin B, mehods and systems |
| US9061027B2 (en) | 2004-08-27 | 2015-06-23 | Board Of Regents, The University Of Texas System | Enhanced delivery of drug compositions to treat life threatening infections |
| CA2623256A1 (en) * | 2005-09-29 | 2007-04-12 | Nektar Therapeutics | Receptacles and kits, such as for dry powder packaging |
| ITMI20051999A1 (it) * | 2005-10-21 | 2007-04-22 | Eratech S R L | Formulazioni inalatorie di farmaci in fora di polvere secca per somministrazione come tale o con nebulizzatore e dotate di elevata erogabilita' respirabilita' e stabilita' |
| US20120128728A1 (en) * | 2005-12-28 | 2012-05-24 | Novartis Pharma Ag | Compositions Comprising Amphotericin B |
| EP1986679B1 (en) * | 2006-02-22 | 2017-10-25 | MannKind Corporation | A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent |
| DE102006053375A1 (de) * | 2006-11-10 | 2008-05-15 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Mischung von Pulvern |
| MY152789A (en) * | 2007-07-31 | 2014-11-28 | Otsuka Pharma Co Ltd | Methods for producing aripiprazole suspension and freeze-dried formulation |
| EP2050437A1 (en) * | 2007-10-15 | 2009-04-22 | Laboratoires SMB | Improved pharmaceutical dry powder compositions for inhalation. |
| PL220269B1 (pl) | 2008-04-21 | 2015-09-30 | Przedsiębiorstwo Produkcji Farmaceutycznej Hasco Lek Spółka Akcyjna | Kompozytowy nośnik leków proszkowych, sposób wytwarzania nośnika leków oraz urządzenie do wytwarzania cząstek nośnika kompozytowego |
| WO2009140587A1 (en) | 2008-05-15 | 2009-11-19 | Novartis Ag | Pulmonary delivery of a fluoroquinolone |
| CA2835771C (en) | 2009-03-18 | 2017-01-24 | Incarda Therapeutics, Inc. | Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration |
| WO2010111132A2 (en) | 2009-03-27 | 2010-09-30 | Bend Research, Inc. | Spray-drying process |
| GB0908129D0 (en) * | 2009-05-12 | 2009-06-24 | Innovata Ltd | Composition |
| TR200904500A2 (tr) | 2009-06-10 | 2009-10-21 | Öner Levent | Ezetimib nanokristallerinin hazırlanması için yöntem ve farmasötik formülasyonları. |
| US9084976B2 (en) | 2010-09-03 | 2015-07-21 | Bend Research, Inc. | Spray-drying apparatus and methods of using the same |
| PT2611530T (pt) | 2010-09-03 | 2019-05-09 | Bend Res Inc | Aparelho de secagem por pulverização e métodos de utilização do mesmo |
| WO2012040502A1 (en) | 2010-09-24 | 2012-03-29 | Bend Research, Inc. | High-temperature spray drying process and apparatus |
| CN103228266B (zh) | 2010-10-29 | 2017-11-14 | 健康科学西部大学 | 三元混合物制剂 |
| JOP20120023B1 (ar) | 2011-02-04 | 2022-03-14 | Novartis Ag | صياغات مساحيق جافة من جسيمات تحتوي على واحد أو اثنين من المواد الفعالة لعلاج امراض ممرات الهواء الانسدادية او الالتهابية |
| KR20160142283A (ko) * | 2014-02-03 | 2016-12-12 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | 아연 프로토포르피린의 마이크로입자 전달용 제형물 |
| WO2016067132A1 (en) | 2014-10-31 | 2016-05-06 | Bend Research Inc. | Process for forming active domains dispersed in a matrix |
| CN104587457B (zh) * | 2015-01-13 | 2017-03-22 | 广东海大畜牧兽医研究院有限公司 | 一种利用难溶或不溶蛋白、多肽抗原制备纳米微粒疫苗的方法 |
| MX2018007512A (es) * | 2015-12-24 | 2018-09-17 | Philip Morris Products Sa | Capsula de particula de nicotina. |
| CN114847965A (zh) | 2016-02-01 | 2022-08-05 | 英凯达治疗公司 | 电子监测联合吸入药理学疗法管理心律失常 |
| CA3060702A1 (en) | 2017-05-10 | 2018-11-15 | Incarda Therapeutics, Inc. | Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration |
| MY200258A (en) * | 2017-06-28 | 2023-12-17 | Philip Morris Products Sa | Container with particles for use with inhaler |
| ES3040411T3 (en) | 2018-03-22 | 2025-10-30 | Incarda Therapeutics Inc | A novel method to slow ventricular rate |
| GB201817863D0 (en) | 2018-11-01 | 2018-12-19 | Nicoventures Trading Ltd | Aerosolisable formulation |
| GB201817865D0 (en) * | 2018-11-01 | 2018-12-19 | Nicoventures Trading Ltd | Aerosolisable formulation |
| GB201817860D0 (en) | 2018-11-01 | 2018-12-19 | Nicoventures Trading Ltd | Aerosolised formulation |
| KR102891439B1 (ko) | 2019-08-01 | 2025-11-25 | 인카다 테라퓨틱스, 인크. | 항부정맥 제제 |
| US11007185B2 (en) | 2019-08-01 | 2021-05-18 | Incarda Therapeutics, Inc. | Antiarrhythmic formulation |
| KR20240164801A (ko) | 2022-03-21 | 2024-11-20 | 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 | 암포테리신 b의 지질-코팅된 결정을 포함하는 이온 채널 보형 조성물 |
| US12605394B2 (en) | 2024-07-25 | 2026-04-21 | Visionary Assets, Llc | Compositions containing cannabinoid nanoparticles |
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| ES2525087T5 (es) † | 2000-05-10 | 2018-06-28 | Novartis Ag | Polvos basados en fosfolípidos para administración de fármacos |
| US6357490B1 (en) * | 2000-08-22 | 2002-03-19 | Advanced Inhalation Research, Inc. | System, method and apparatus for filling containers |
| CA2432319A1 (en) * | 2000-12-21 | 2002-07-18 | Nektar Therapeutics | Pulmonary delivery of polyene antifungal agents |
-
2003
- 2003-12-31 TR TR2005/02522T patent/TR200502522T2/xx unknown
- 2003-12-31 BR BR0317810-2A patent/BR0317810A/pt not_active IP Right Cessation
- 2003-12-31 WO PCT/US2003/041703 patent/WO2004060351A2/en not_active Ceased
- 2003-12-31 PT PT38003950T patent/PT1589947T/pt unknown
- 2003-12-31 PL PL378270A patent/PL378270A1/pl unknown
- 2003-12-31 US US10/750,934 patent/US20040156792A1/en not_active Abandoned
- 2003-12-31 MX MXPA05007158A patent/MXPA05007158A/es unknown
- 2003-12-31 JP JP2004564917A patent/JP2006513236A/ja not_active Withdrawn
- 2003-12-31 HU HU0500846A patent/HUP0500846A3/hu unknown
- 2003-12-31 ES ES03800395T patent/ES2589578T5/es not_active Expired - Lifetime
- 2003-12-31 CA CA2511523A patent/CA2511523C/en not_active Expired - Fee Related
- 2003-12-31 CN CNA2003801091328A patent/CN1741789A/zh active Pending
- 2003-12-31 KR KR1020057012444A patent/KR20050095838A/ko not_active Withdrawn
- 2003-12-31 AU AU2003300137A patent/AU2003300137A1/en not_active Abandoned
- 2003-12-31 EA EA200501001A patent/EA200501001A1/ru unknown
- 2003-12-31 EP EP03800395.0A patent/EP1589947B2/en not_active Expired - Lifetime
-
2005
- 2005-06-23 NO NO20053076A patent/NO20053076L/no not_active Application Discontinuation
- 2005-06-24 ZA ZA200505155A patent/ZA200505155B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0500846A3 (en) | 2008-10-28 |
| PL378270A1 (pl) | 2006-03-20 |
| ES2589578T5 (es) | 2019-07-23 |
| ES2589578T3 (es) | 2016-11-15 |
| CA2511523C (en) | 2013-10-15 |
| NO20053076L (no) | 2005-09-13 |
| ZA200505155B (en) | 2006-04-26 |
| CA2511523A1 (en) | 2004-07-22 |
| NO20053076D0 (no) | 2005-06-23 |
| EA200501001A1 (ru) | 2005-12-29 |
| JP2006513236A (ja) | 2006-04-20 |
| BR0317810A (pt) | 2005-11-29 |
| CN1741789A (zh) | 2006-03-01 |
| WO2004060351A3 (en) | 2004-09-30 |
| KR20050095838A (ko) | 2005-10-04 |
| US20040156792A1 (en) | 2004-08-12 |
| EP1589947B1 (en) | 2016-06-15 |
| PT1589947T (pt) | 2016-09-05 |
| EP1589947B8 (en) | 2016-08-24 |
| WO2004060351A2 (en) | 2004-07-22 |
| TR200502522T2 (tr) | 2005-09-21 |
| EP1589947B2 (en) | 2019-01-30 |
| HUP0500846A2 (en) | 2008-05-28 |
| MXPA05007158A (es) | 2005-09-21 |
| EP1589947A2 (en) | 2005-11-02 |
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| PC1 | Assignment before grant (sect. 113) |
Owner name: NOVARTIS AG Free format text: FORMER APPLICANT(S): NEKTAR THERAPEUTICS |
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| MK5 | Application lapsed section 142(2)(e) - patent request and compl. specification not accepted |