AU2003279444A1 - Conjugates of tc complexes and targeting moieties and their use in mri diagnostic - Google Patents

Conjugates of tc complexes and targeting moieties and their use in mri diagnostic Download PDF

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Publication number
AU2003279444A1
AU2003279444A1 AU2003279444A AU2003279444A AU2003279444A1 AU 2003279444 A1 AU2003279444 A1 AU 2003279444A1 AU 2003279444 A AU2003279444 A AU 2003279444A AU 2003279444 A AU2003279444 A AU 2003279444A AU 2003279444 A1 AU2003279444 A1 AU 2003279444A1
Authority
AU
Australia
Prior art keywords
complex composition
technetium
technetium complex
acid
kit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003279444A
Other languages
English (en)
Inventor
David Jonathan Barnett
Georg Brauers
Gillian Farrar
Joanne Sarah Lewis
Harry John Wadsworth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare Ltd
Original Assignee
GE Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare Ltd filed Critical GE Healthcare Ltd
Publication of AU2003279444A1 publication Critical patent/AU2003279444A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4732—Casein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2003279444A 2002-10-25 2003-10-24 Conjugates of tc complexes and targeting moieties and their use in mri diagnostic Abandoned AU2003279444A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0224799.7 2002-10-25
GBGB0224799.7A GB0224799D0 (en) 2002-10-25 2002-10-25 Improved complex compositions
PCT/GB2003/004573 WO2004037297A1 (en) 2002-10-25 2003-10-24 Conjugates of tc complexes and targeting moieties and their use in mri diagnostic

Publications (1)

Publication Number Publication Date
AU2003279444A1 true AU2003279444A1 (en) 2004-05-13

Family

ID=9946533

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003279444A Abandoned AU2003279444A1 (en) 2002-10-25 2003-10-24 Conjugates of tc complexes and targeting moieties and their use in mri diagnostic

Country Status (16)

Country Link
EP (1) EP1553986B1 (enExample)
JP (1) JP2006508084A (enExample)
KR (1) KR20050070080A (enExample)
CN (1) CN1708322A (enExample)
AT (1) ATE402720T1 (enExample)
AU (1) AU2003279444A1 (enExample)
BR (1) BR0315578A (enExample)
CA (1) CA2501684A1 (enExample)
DE (1) DE60322562D1 (enExample)
ES (1) ES2309361T3 (enExample)
GB (1) GB0224799D0 (enExample)
MX (1) MXPA05004418A (enExample)
NO (1) NO20051811L (enExample)
RU (1) RU2005110960A (enExample)
WO (1) WO2004037297A1 (enExample)
ZA (1) ZA200502835B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0515974D0 (en) * 2005-08-03 2005-09-07 Ge Healthcare Ltd Compounds and imaging methods
GB0520527D0 (en) * 2005-10-10 2005-11-16 Ge Healthcare Ltd Automated method
GB0614337D0 (en) * 2006-07-19 2006-08-30 Acal Energy Ltd Fuel Cells
US20120165650A1 (en) 2010-12-22 2012-06-28 General Electric Company Her2 binders
ES2804509T3 (es) 2010-07-27 2021-02-08 Serac Healthcare Ltd Composiciones radiofarmacéuticas
ES2739504T3 (es) 2010-12-21 2020-01-31 Ge Healthcare Ltd Uso de anilina en la radioestabilización de una ligadura de oxima
JP5934246B2 (ja) * 2010-12-22 2016-06-15 テーエフシム グリコ−ｃｆ２−セリンおよびグリコ−ｃｆ２−トレオニンの誘導体
GB201103696D0 (en) * 2011-03-04 2011-04-20 Ge Healthcare Ltd Technetium labelled peptides
US20130195756A1 (en) * 2012-01-31 2013-08-01 General Electric Company 99mTc IMAGING AGENTS AND METHODS OF USE
GB201610176D0 (en) * 2016-06-10 2016-07-27 Edinburgh Molecular Imaging Ltd Imaging agents and methods of use
CN112830940B (zh) * 2020-09-07 2022-03-01 中国科学院宁波材料技术与工程研究所 2,5-呋喃二甲醛肟金属络合物及其制备方法、及在抗菌除霉消毒剂中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69937996T2 (de) * 1998-05-15 2009-01-02 Ge Healthcare Ltd., Little Chalfont Markierte glutamin- und lysinanaloge
WO2001077145A2 (en) * 2000-04-12 2001-10-18 Amersham Health As Integrin binding peptide derivatives
WO2001089584A2 (en) * 2000-05-23 2001-11-29 Amersham Health As Contrast agents
NO20004795D0 (no) * 2000-09-26 2000-09-26 Nycomed Imaging As Peptidbaserte forbindelser
GB0105224D0 (en) * 2001-03-02 2001-04-18 Nycomed Amersham Plc Improved peptide-chelate conjugates

Also Published As

Publication number Publication date
BR0315578A (pt) 2005-10-25
KR20050070080A (ko) 2005-07-05
WO2004037297A1 (en) 2004-05-06
NO20051811D0 (no) 2005-04-14
ES2309361T3 (es) 2008-12-16
CN1708322A (zh) 2005-12-14
MXPA05004418A (es) 2005-11-23
EP1553986A1 (en) 2005-07-20
DE60322562D1 (de) 2008-09-11
RU2005110960A (ru) 2005-11-20
ZA200502835B (en) 2006-03-29
GB0224799D0 (en) 2002-12-04
ATE402720T1 (de) 2008-08-15
EP1553986B1 (en) 2008-07-30
CA2501684A1 (en) 2004-05-06
JP2006508084A (ja) 2006-03-09
NO20051811L (no) 2005-06-27

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Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted