ATE402720T1 - Konjugate von tc komplexen und zielgerichtete einheiten und ihre verwendung in nmr-diagnostik - Google Patents
Konjugate von tc komplexen und zielgerichtete einheiten und ihre verwendung in nmr-diagnostikInfo
- Publication number
- ATE402720T1 ATE402720T1 AT03772392T AT03772392T ATE402720T1 AT E402720 T1 ATE402720 T1 AT E402720T1 AT 03772392 T AT03772392 T AT 03772392T AT 03772392 T AT03772392 T AT 03772392T AT E402720 T1 ATE402720 T1 AT E402720T1
- Authority
- AT
- Austria
- Prior art keywords
- technetium
- aza
- diaminedioxime
- conjugates
- complexes
- Prior art date
Links
- 229910052713 technetium Inorganic materials 0.000 abstract 4
- GKLVYJBZJHMRIY-UHFFFAOYSA-N technetium atom Chemical compound [Tc] GKLVYJBZJHMRIY-UHFFFAOYSA-N 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 239000012217 radiopharmaceutical Substances 0.000 abstract 2
- 229940121896 radiopharmaceutical Drugs 0.000 abstract 2
- 230000002799 radiopharmaceutical effect Effects 0.000 abstract 2
- 239000002738 chelating agent Substances 0.000 abstract 1
- 238000010668 complexation reaction Methods 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- -1 technetium metal complex Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4732—Casein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Optics & Photonics (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0224799.7A GB0224799D0 (en) | 2002-10-25 | 2002-10-25 | Improved complex compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE402720T1 true ATE402720T1 (de) | 2008-08-15 |
Family
ID=9946533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03772392T ATE402720T1 (de) | 2002-10-25 | 2003-10-24 | Konjugate von tc komplexen und zielgerichtete einheiten und ihre verwendung in nmr-diagnostik |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1553986B1 (enExample) |
| JP (1) | JP2006508084A (enExample) |
| KR (1) | KR20050070080A (enExample) |
| CN (1) | CN1708322A (enExample) |
| AT (1) | ATE402720T1 (enExample) |
| AU (1) | AU2003279444A1 (enExample) |
| BR (1) | BR0315578A (enExample) |
| CA (1) | CA2501684A1 (enExample) |
| DE (1) | DE60322562D1 (enExample) |
| ES (1) | ES2309361T3 (enExample) |
| GB (1) | GB0224799D0 (enExample) |
| MX (1) | MXPA05004418A (enExample) |
| NO (1) | NO20051811L (enExample) |
| RU (1) | RU2005110960A (enExample) |
| WO (1) | WO2004037297A1 (enExample) |
| ZA (1) | ZA200502835B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0515974D0 (en) * | 2005-08-03 | 2005-09-07 | Ge Healthcare Ltd | Compounds and imaging methods |
| GB0520527D0 (en) * | 2005-10-10 | 2005-11-16 | Ge Healthcare Ltd | Automated method |
| GB0614337D0 (en) * | 2006-07-19 | 2006-08-30 | Acal Energy Ltd | Fuel Cells |
| US20120165650A1 (en) | 2010-12-22 | 2012-06-28 | General Electric Company | Her2 binders |
| ES2804509T3 (es) | 2010-07-27 | 2021-02-08 | Serac Healthcare Ltd | Composiciones radiofarmacéuticas |
| ES2739504T3 (es) | 2010-12-21 | 2020-01-31 | Ge Healthcare Ltd | Uso de anilina en la radioestabilización de una ligadura de oxima |
| JP5934246B2 (ja) * | 2010-12-22 | 2016-06-15 | テーエフシム | グリコ−ｃｆ２−セリンおよびグリコ−ｃｆ２−トレオニンの誘導体 |
| GB201103696D0 (en) * | 2011-03-04 | 2011-04-20 | Ge Healthcare Ltd | Technetium labelled peptides |
| US20130195756A1 (en) * | 2012-01-31 | 2013-08-01 | General Electric Company | 99mTc IMAGING AGENTS AND METHODS OF USE |
| GB201610176D0 (en) * | 2016-06-10 | 2016-07-27 | Edinburgh Molecular Imaging Ltd | Imaging agents and methods of use |
| CN112830940B (zh) * | 2020-09-07 | 2022-03-01 | 中国科学院宁波材料技术与工程研究所 | 2,5-呋喃二甲醛肟金属络合物及其制备方法、及在抗菌除霉消毒剂中的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69937996T2 (de) * | 1998-05-15 | 2009-01-02 | Ge Healthcare Ltd., Little Chalfont | Markierte glutamin- und lysinanaloge |
| WO2001077145A2 (en) * | 2000-04-12 | 2001-10-18 | Amersham Health As | Integrin binding peptide derivatives |
| WO2001089584A2 (en) * | 2000-05-23 | 2001-11-29 | Amersham Health As | Contrast agents |
| NO20004795D0 (no) * | 2000-09-26 | 2000-09-26 | Nycomed Imaging As | Peptidbaserte forbindelser |
| GB0105224D0 (en) * | 2001-03-02 | 2001-04-18 | Nycomed Amersham Plc | Improved peptide-chelate conjugates |
-
2002
- 2002-10-25 GB GBGB0224799.7A patent/GB0224799D0/en not_active Ceased
-
2003
- 2003-10-24 WO PCT/GB2003/004573 patent/WO2004037297A1/en not_active Ceased
- 2003-10-24 CN CNA2003801020619A patent/CN1708322A/zh active Pending
- 2003-10-24 RU RU2005110960/15A patent/RU2005110960A/ru not_active Application Discontinuation
- 2003-10-24 MX MXPA05004418A patent/MXPA05004418A/es not_active Application Discontinuation
- 2003-10-24 AT AT03772392T patent/ATE402720T1/de not_active IP Right Cessation
- 2003-10-24 BR BR0315578-1A patent/BR0315578A/pt not_active IP Right Cessation
- 2003-10-24 ES ES03772392T patent/ES2309361T3/es not_active Expired - Lifetime
- 2003-10-24 EP EP03772392A patent/EP1553986B1/en not_active Expired - Lifetime
- 2003-10-24 CA CA002501684A patent/CA2501684A1/en not_active Abandoned
- 2003-10-24 AU AU2003279444A patent/AU2003279444A1/en not_active Abandoned
- 2003-10-24 JP JP2004546174A patent/JP2006508084A/ja not_active Withdrawn
- 2003-10-24 KR KR1020057006999A patent/KR20050070080A/ko not_active Withdrawn
- 2003-10-24 DE DE60322562T patent/DE60322562D1/de not_active Expired - Lifetime
-
2005
- 2005-04-14 NO NO20051811A patent/NO20051811L/no not_active Application Discontinuation
-
2006
- 2006-01-19 ZA ZA200502835A patent/ZA200502835B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR0315578A (pt) | 2005-10-25 |
| KR20050070080A (ko) | 2005-07-05 |
| WO2004037297A1 (en) | 2004-05-06 |
| NO20051811D0 (no) | 2005-04-14 |
| ES2309361T3 (es) | 2008-12-16 |
| CN1708322A (zh) | 2005-12-14 |
| MXPA05004418A (es) | 2005-11-23 |
| EP1553986A1 (en) | 2005-07-20 |
| DE60322562D1 (de) | 2008-09-11 |
| RU2005110960A (ru) | 2005-11-20 |
| ZA200502835B (en) | 2006-03-29 |
| GB0224799D0 (en) | 2002-12-04 |
| EP1553986B1 (en) | 2008-07-30 |
| CA2501684A1 (en) | 2004-05-06 |
| JP2006508084A (ja) | 2006-03-09 |
| AU2003279444A1 (en) | 2004-05-13 |
| NO20051811L (no) | 2005-06-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR0210965A (pt) | Conjugado de quelador, complexo de radiometal, radiofármaco, kit para a preparação do mesmo, composto, e, processo para a preparação do mesmo | |
| ATE487498T1 (de) | Verbesserte radiometall-komplex-zusammensetzungen | |
| Ramogida et al. | H2 CHX dedpa and H4 CHX octapa Chiral Acyclic Chelating Ligands for 67/68Ga and 111In Radiopharmaceuticals | |
| ATE402720T1 (de) | Konjugate von tc komplexen und zielgerichtete einheiten und ihre verwendung in nmr-diagnostik | |
| Liu et al. | Labeling biomolecules with radiorhenium-A review of the bifunctional chelators | |
| WO2007042781A3 (en) | Automated method for preparing technetium complexes | |
| IL175667A (en) | Imaging factor that includes a synthetic caspase-3 inhibitor marked with the neuroimaging agent, a radiopharmaceutical containing it, a kit for preparation of the preparation and a method for diagnosis based on it | |
| DE60111729D1 (de) | Ternärligand-Komplexe verwendbar als Radiopharmazeutika | |
| NO20070348L (no) | Improved N4 Chelator Conjugates | |
| ATE556722T1 (de) | Herstellung von vierzähnigen peptidchelatkonjugaten zur diagnose von kolorektalem krebs | |
| Rattat et al. | Comparison of tridentate ligands in competition experiments for their ability to form a [99mTc (CO) 3] complex | |
| DE69723242D1 (de) | Ternäre radiopharmazeutische komplexe | |
| Banerjee et al. | Site directed maleimide bifunctional chelators for the M (CO) 3+ core (M= 99m Tc, Re) | |
| Su et al. | A Novel Amine− Dioxime Chelator for Technetium-99m: Synthesis and Evaluation of 2-Nitroimidazole-Containing Analogues as Markers for Hypoxic Cells | |
| NO20055334L (no) | Bifunksjonelle tridentate pyrazolylinneholdende ligander for RE og TC trikarbonylkomplekser | |
| Xu et al. | Synthesis and evaluation of hydroxamamide-based tetradentate ligands as a new class of thiol-free chelating molecules for 99mTc radiopharmaceuticals | |
| GB0421987D0 (en) | Novel technetium and rhenium complexes | |
| Rey et al. | Synthesis and characterization of mixed-ligand oxorhenium complexes with the SNN type of ligand. Isolation of a novel ReO [SN][S][S] complex | |
| WO2003027148A8 (en) | Disulfide-reduced neogalactosyl serum albumin and use of radiolabeled derivative thereof for liver imaging | |
| US20020082398A1 (en) | Cores for technetium radiopharmaceuticals | |
| Grimminger | Rhenium (V)-carbohydrate complexes with amino acids | |
| Ferdani et al. | Synthesis, Cu (II) complexation, 64Cu-labeling and biological evaluation of CB-TE1A1P | |
| Holland et al. | 89Zr-chemistry in the design of novel radiotracers for immunoPET |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |