AU2003279084A1 - Novel compositions and methods for the treatment of psoriasis - Google Patents

Novel compositions and methods for the treatment of psoriasis Download PDF

Info

Publication number
AU2003279084A1
AU2003279084A1 AU2003279084A AU2003279084A AU2003279084A1 AU 2003279084 A1 AU2003279084 A1 AU 2003279084A1 AU 2003279084 A AU2003279084 A AU 2003279084A AU 2003279084 A AU2003279084 A AU 2003279084A AU 2003279084 A1 AU2003279084 A1 AU 2003279084A1
Authority
AU
Australia
Prior art keywords
seq
shows
sequence
cdna
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003279084A
Other languages
English (en)
Inventor
Sarah Bodary
Hilary Clark
Janet Jackman
Jill Schoenfeld
P Mickey Williams
William I. Wood
Thomas D. Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of AU2003279084A1 publication Critical patent/AU2003279084A1/en
Priority to AU2010203031A priority Critical patent/AU2010203031B2/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6881—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/20—Dermatological disorders
    • G01N2800/205—Scaling palpular diseases, e.g. psoriasis, pytiriasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • General Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Peptides Or Proteins (AREA)
AU2003279084A 2002-09-25 2003-09-25 Novel compositions and methods for the treatment of psoriasis Abandoned AU2003279084A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2010203031A AU2010203031B2 (en) 2002-09-25 2010-07-16 Novel compositions and methods for the treatment of psoriasis

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41400602P 2002-09-25 2002-09-25
US60/414,006 2002-09-25
PCT/US2003/030907 WO2004028479A2 (en) 2002-09-25 2003-09-25 Nouvelles compositions et methodes de traitement du psoriasis

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2010203031A Division AU2010203031B2 (en) 2002-09-25 2010-07-16 Novel compositions and methods for the treatment of psoriasis

Publications (1)

Publication Number Publication Date
AU2003279084A1 true AU2003279084A1 (en) 2004-04-19

Family

ID=32043325

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2003279084A Abandoned AU2003279084A1 (en) 2002-09-25 2003-09-25 Novel compositions and methods for the treatment of psoriasis
AU2010203031A Ceased AU2010203031B2 (en) 2002-09-25 2010-07-16 Novel compositions and methods for the treatment of psoriasis

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2010203031A Ceased AU2010203031B2 (en) 2002-09-25 2010-07-16 Novel compositions and methods for the treatment of psoriasis

Country Status (6)

Country Link
US (3) US20070042945A1 (enExample)
EP (2) EP2500438A3 (enExample)
JP (2) JP2006513700A (enExample)
AU (2) AU2003279084A1 (enExample)
CA (1) CA2499843A1 (enExample)
WO (1) WO2004028479A2 (enExample)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7638284B2 (en) * 2000-10-31 2009-12-29 The Curators Of The University Of Missouri Immunoglobulin A inducing protein and uses therefor
US7449548B2 (en) 2001-12-07 2008-11-11 Agensys, Inc. Nucleic acid and corresponding protein entitled 193P1E1B useful in treatment and detection of cancer
US7803906B2 (en) * 2002-03-22 2010-09-28 Gene Signal International Sa Composition comprising an angiogenesis related protein
US20040081653A1 (en) 2002-08-16 2004-04-29 Raitano Arthur B. Nucleic acids and corresponding proteins entitled 251P5G2 useful in treatment and detection of cancer
EP2500438A3 (en) * 2002-09-25 2012-11-28 Genentech, Inc. Novel compositions and methods for the treatment of psoriasis
CA2508948A1 (en) 2002-12-16 2004-07-15 Halozyme, Inc. Human chondroitinase glycoprotein (chasegp), process for preparing the same, and pharmaceutical compositions comprising thereof
WO2005051988A2 (en) * 2003-03-03 2005-06-09 Genentech, Inc. Compositions and methods for the treatment of systemic lupus erythematosis
AU2004219603A1 (en) * 2003-03-11 2004-09-23 Genentech, Inc. Novel compositions and methods for the treatment of immune related disease
DE602004029058D1 (de) * 2003-07-09 2010-10-21 Shinonogi & Co Ltd Inducer von atopischer dermatitis
WO2005019258A2 (en) * 2003-08-11 2005-03-03 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
US7473541B2 (en) * 2004-07-09 2009-01-06 Gross Richard W Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities
WO2005059099A2 (en) * 2003-12-11 2005-06-30 Washington University In St.Louis Human ipla2t
US20050186577A1 (en) 2004-02-20 2005-08-25 Yixin Wang Breast cancer prognostics
US7960100B1 (en) 2004-04-30 2011-06-14 Celera Corporation Colon cancer targets and uses thereof
US20090253770A1 (en) * 2004-05-18 2009-10-08 Kurume University Target gene mimitin of myc
GB0414325D0 (en) * 2004-06-25 2004-07-28 Celltech R&D Ltd A protein involved in cancer
WO2006017171A2 (en) * 2004-07-13 2006-02-16 Metabolex, Inc. Methods of diagnosing & treating obesity, diabetes and insulin resistance
AU2005316169B2 (en) * 2004-12-13 2011-11-17 Alethia Biotherapeutics Inc. Polynucleotides and polypeptide sequences involved in the process of bone remodeling
EP1851543A2 (en) 2005-02-24 2007-11-07 Compugen Ltd. Novel diagnostic markers, especially for in vivo imaging, and assays and methods of use thereof
CA2621992C (en) * 2005-09-09 2020-08-04 The Johns Hopkins University Manipulation of regulatory t cell and dc function by targeting neuritin gene using antibodies, agonists and antagonists
JP5376948B2 (ja) 2005-09-13 2013-12-25 ナショナル リサーチ カウンシル オブ カナダ 腫瘍細胞活性を調節する方法及び組成物
WO2007036021A1 (en) * 2005-09-27 2007-04-05 National Research Council Of Canada Blood-brain barrier epitopes and uses thereof
DE102005059242A1 (de) * 2005-12-12 2007-06-14 Johannes Gutenberg-Universität Mainz, Vertreten Durch Den Präsidenten Molekulare Marker für eine Tumordiagnose und -therapie
US20090270480A1 (en) * 2005-12-28 2009-10-29 Bernard Amegadzie Markers and Methods for Assessing and Treating Psoriasis and Related Disorders
US20090156540A1 (en) * 2006-03-07 2009-06-18 Mckenna Katherine Method for diagnosing and/or predicting the development of an allergic disorder and agents for treating and/or preventing same
FR2908784B1 (fr) 2006-11-17 2012-12-14 Oreal Utilisation cosmetique d'une proteine de la famille des ribonucleases
FR2908654B1 (fr) 2006-11-20 2014-04-04 Oreal Utilisation cosmetique de proteines de type chitinase
WO2008089440A2 (en) * 2007-01-18 2008-07-24 University Of Utah Research Foundation Compositions and methods for detecting, treating, or preventing reductive stress
EP2158317B1 (en) 2007-05-16 2018-03-28 Gene Signal International Sa Anti-tumor drug, medicament, composition, and use thereof
US9808506B2 (en) 2007-10-19 2017-11-07 Rappaport Family Institute For Research In The Medical Sciences Compositions comprising semaphorins for the treatment of cancer and methods of selection thereof
AU2008313274A1 (en) * 2007-10-19 2009-04-23 Rappaport Family Institute For Research In The Medical Sciences Compositions comprising semaphorins for the treatment of angiogenesis related diseases and methods of selection thereof
US8168586B1 (en) 2007-11-21 2012-05-01 Celera Corporation Cancer targets and uses thereof
FR2925314B1 (fr) * 2007-12-19 2012-11-23 Oreal Utilisation cosmetique de proteines de type transglutaminase 3
DE102008033381B4 (de) * 2008-07-07 2013-12-24 Alexander Steinle Modulation der Immunantwort durch den Rezeptor NKp65 und seine Liganden
WO2011063523A1 (en) 2009-11-24 2011-06-03 Alethia Biotherapeutics Inc. Anti-clusterin antibodies and antigen binding fragments and their use to reduce tumor volume
WO2011106839A1 (en) * 2010-03-03 2011-09-09 Children's Cancer Institute Australia for Medical Research Skin cancer prevention and treatment
CA2862739A1 (en) 2012-02-22 2013-08-29 Alethia Biotherapeutics Inc. Co-use of a clusterin inhibitor with an egfr inhibitor to treat cancer
KR20150023904A (ko) 2012-06-27 2015-03-05 버그 엘엘씨 전립선암의 진단 및 치료에서의 마커의 용도
GB201300684D0 (en) 2013-01-15 2013-02-27 Apitope Int Nv Peptide
US10201610B2 (en) * 2014-10-20 2019-02-12 The University Of Western Australia Interference peptides and use thereof
SG11201704660YA (en) 2014-12-08 2017-07-28 Berg Llc Use of markers including filamin a in the diagnosis and treatment of prostate cancer
AU2016235437B2 (en) * 2015-03-20 2019-05-09 The Trustees Of The University Of Pennsylvania ISG15 and its use as an adjuvant
BR112021010374A2 (pt) 2018-12-21 2021-08-24 23Andme, Inc. Anticorpos anti-il-36 e métodos de uso dos mesmos
KR102065171B1 (ko) * 2019-02-20 2020-01-13 (주)케어젠 대기오염물질에 의한 피부 손상 방지 및 항노화용 펩타이드와 이의 용도
CN112175949B (zh) * 2020-09-23 2021-05-04 山东大学第二医院 lncRNA RP11-394O4.6在抑制膀胱癌细胞生物学功能中的应用
WO2024246046A1 (en) 2023-05-31 2024-12-05 Corequest Sagl Gene delivery to cells of vectors comprising crat nucleotidic or aminoacidic sequences

Family Cites Families (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
FR2413974A1 (fr) 1978-01-06 1979-08-03 David Bernard Sechoir pour feuilles imprimees par serigraphie
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
JPS6023084B2 (ja) 1979-07-11 1985-06-05 味の素株式会社 代用血液
US4399216A (en) 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
ZA811368B (en) 1980-03-24 1982-04-28 Genentech Inc Bacterial polypedtide expression employing tryptophan promoter-operator
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4873191A (en) 1981-06-12 1989-10-10 Ohio University Genetic transformation of zygotes
US4485045A (en) 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
NZ201705A (en) 1981-08-31 1986-03-14 Genentech Inc Recombinant dna method for production of hepatitis b surface antigen in yeast
US4640835A (en) 1981-10-30 1987-02-03 Nippon Chemiphar Company, Ltd. Plasminogen activator derivatives
US4943529A (en) 1982-05-19 1990-07-24 Gist-Brocades Nv Kluyveromyces as a host strain
US4713339A (en) 1983-01-19 1987-12-15 Genentech, Inc. Polycistronic expression vector construction
AU2353384A (en) 1983-01-19 1984-07-26 Genentech Inc. Amplification in eukaryotic host cells
NZ207394A (en) 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4675187A (en) 1983-05-16 1987-06-23 Bristol-Myers Company BBM-1675, a new antibiotic complex
DD266710A3 (de) 1983-06-06 1989-04-12 Ve Forschungszentrum Biotechnologie Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase
US4544545A (en) 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
AU3145184A (en) 1983-08-16 1985-02-21 Zymogenetics Inc. High expression of foreign genes in schizosaccharomyces pombe
US4496689A (en) 1983-12-27 1985-01-29 Miles Laboratories, Inc. Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
US4736866B1 (en) 1984-06-22 1988-04-12 Transgenic non-human mammals
US4879231A (en) 1984-10-30 1989-11-07 Phillips Petroleum Company Transformation of yeasts of the genus pichia
EP0206448B1 (en) 1985-06-19 1990-11-14 Ajinomoto Co., Inc. Hemoglobin combined with a poly(alkylene oxide)
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
EP0272253A4 (en) 1986-03-07 1990-02-05 Massachusetts Inst Technology METHOD FOR IMPROVING GLYCOPROTE INSTABILITY.
GB8610600D0 (en) 1986-04-30 1986-06-04 Novo Industri As Transformation of trichoderma
US4791192A (en) 1986-06-26 1988-12-13 Takeda Chemical Industries, Ltd. Chemically modified protein with polyethyleneglycol
US4946783A (en) 1987-01-30 1990-08-07 President And Fellows Of Harvard College Periplasmic protease mutants of Escherichia coli
US5223425A (en) * 1987-04-02 1993-06-29 The Beth Israel Hospital Association DNA encoding human adipsin with complement D activity
US5010182A (en) 1987-07-28 1991-04-23 Chiron Corporation DNA constructs containing a Kluyveromyces alpha factor leader sequence for directing secretion of heterologous polypeptides
IL87737A (en) 1987-09-11 1993-08-18 Genentech Inc Method for culturing polypeptide factor dependent vertebrate recombinant cells
GB8724885D0 (en) 1987-10-23 1987-11-25 Binns M M Fowlpox virus promotors
JPH04501201A (ja) 1987-12-21 1992-03-05 ジ・アップジョン・カンパニー 発芽植物種子類のアグロバクテリウム媒介形質転換
AU4005289A (en) 1988-08-25 1990-03-01 Smithkline Beecham Corporation Recombinant saccharomyces
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
US5225538A (en) 1989-02-23 1993-07-06 Genentech, Inc. Lymphocyte homing receptor/immunoglobulin fusion proteins
FR2646437B1 (fr) 1989-04-28 1991-08-30 Transgene Sa Nouvelles sequences d'adn, leur application en tant que sequence codant pour un peptide signal pour la secretion de proteines matures par des levures recombinantes, cassettes d'expression, levures transformees et procede de preparation de proteines correspondant
DE394538T1 (de) 1989-04-28 1991-04-11 Rhein Biotech Ges. Fuer Biotechnologische Prozesse Und Produkte Mbh, 4000 Duesseldorf Hefezellen der schwanniomyces-gattung.
EP0402226A1 (en) 1989-06-06 1990-12-12 Institut National De La Recherche Agronomique Transformation vectors for yeast yarrowia
DE3920358A1 (de) 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
ATE144793T1 (de) 1989-06-29 1996-11-15 Medarex Inc Bispezifische reagenzien für die aids-therapie
FR2649120B1 (fr) 1989-06-30 1994-01-28 Cayla Nouvelle souche et ses mutants de champignons filamenteux, procede de production de proteines recombinantes a l'aide de ladite souche et souches et proteines obtenues selon ce procede
US5013556A (en) 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
JPH06500011A (ja) 1990-06-29 1994-01-06 ラージ　スケール　バイオロジー　コーポレイション 形質転換された微生物によるメラニンの製造
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
KR100272077B1 (ko) 1990-08-29 2000-11-15 젠팜인터내셔날,인코포레이티드 이종 항체를 생산할 수 있는 전이유전자를 가진 인간이외의 동물
US5661016A (en) 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5625126A (en) 1990-08-29 1997-04-29 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US5633425A (en) 1990-08-29 1997-05-27 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
US5122469A (en) 1990-10-03 1992-06-16 Genentech, Inc. Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins
US5206161A (en) 1991-02-01 1993-04-27 Genentech, Inc. Human plasma carboxypeptidase B
WO1993008829A1 (en) 1991-11-04 1993-05-13 The Regents Of The University Of California Compositions that mediate killing of hiv-infected cells
AU3178993A (en) 1991-11-25 1993-06-28 Enzon, Inc. Multivalent antigen-binding proteins
ES2091684T3 (es) 1992-11-13 1996-11-01 Idec Pharma Corp Aplicacion terapeutica de anticuerpos quimericos y radiomarcados contra el antigeno de diferenciacion restringida de los linfocitos b humanos para el tratamiento del linfoma de las celulas b.
EP0616812B1 (en) 1993-03-24 1999-11-03 Berlex Biosciences Combination with anti-hormonal compounds and binding molecules for the treatment of cancer
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
US6458939B1 (en) 1996-03-15 2002-10-01 Millennium Pharmaceuticals, Inc. Compositions and methods for the diagnosis, prevention, and treatment of neoplastic cell growth and proliferation
WO2002008284A2 (en) * 2000-07-20 2002-01-31 Genentech, Inc. Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
US5863769A (en) * 1997-01-28 1999-01-26 Smithkline Beecham Corporation DNA encoding interleukin-1 receptor antagonist (IL-1raβ)
JPH10221340A (ja) * 1997-02-07 1998-08-21 Advanced Sukin Res Kenkyusho:Kk 皮膚疾患の診断方法および薬効評価方法
US20020137890A1 (en) * 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
DE69939813D1 (de) * 1998-02-20 2008-12-11 Tanox Inc Inhibitoren der komplement-aktivierung
AU5772299A (en) * 1998-08-07 2000-02-28 Millennium Pharmaceuticals, Inc. Novel molecules of the tango-93-related protein family and uses thereof
AU6296899A (en) * 1998-10-08 2000-04-26 Zymogenetics Inc. Interleukin-1 homolog
EP2319929A1 (en) * 1998-12-23 2011-05-11 Genentech, Inc. IL-1 related polypeptides
US20020076762A1 (en) * 1999-05-14 2002-06-20 Incyte Pharmaceuticals, Inc. Full-length expressed genetic markers
FR2797402B1 (fr) * 1999-07-15 2004-03-12 Biomerieux Stelhys Utilisation d'un polypeptide pour detecter, prevenir ou traiter un etat pathologique associe a une maladie degenerative, neurologique ou autoimmune
AU6219400A (en) * 1999-07-16 2001-02-05 Interleukin Genetics, Inc. The il-1l1 gene and polypeptide products
EP1686134A3 (en) * 1999-12-01 2006-08-09 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
WO2001086002A2 (en) * 2000-05-09 2001-11-15 Genetics Institute, Llc Compositions, kits, and methods for identification, assessment, prevention, and therapy of psoriasis
EP1294871A1 (en) * 2000-06-21 2003-03-26 Amgen, Inc. Secreted epithelial colon stromal-1 polypeptides, nucleic acids encoding the same and uses thereof
EP2500438A3 (en) * 2002-09-25 2012-11-28 Genentech, Inc. Novel compositions and methods for the treatment of psoriasis

Also Published As

Publication number Publication date
EP2500438A2 (en) 2012-09-19
AU2010203031B2 (en) 2012-12-13
EP2500438A3 (en) 2012-11-28
US20090238832A1 (en) 2009-09-24
CA2499843A1 (en) 2004-04-08
WO2004028479A2 (en) 2004-04-08
AU2010203031A1 (en) 2010-08-05
EP1585482A4 (en) 2009-09-09
JP2010162016A (ja) 2010-07-29
JP2006513700A (ja) 2006-04-27
US20110190144A1 (en) 2011-08-04
EP1585482A2 (en) 2005-10-19
US20070042945A1 (en) 2007-02-22
WO2004028479A9 (en) 2009-04-23

Similar Documents

Publication Publication Date Title
AU2010203031B2 (en) Novel compositions and methods for the treatment of psoriasis
AU2003295401B2 (en) Compositions and methods for the treatment of natural killer cell related diseases
AU2003298607B2 (en) Compositions and methods for the treatment of immune related diseases
US20110182889A1 (en) Compositions and methods for the treatment of natural killer cell related diseases
US20110142841A1 (en) Compositions and methods for the treatment of systemic lupus erythematosis
AU2003284357A1 (en) Compositions and methods for the treatment of immune related diseases
US20120003246A1 (en) Novel composition and methods for the treatment of psoriasis
AU2003276874B2 (en) Novel compositions and methods for the treatment of immune related diseases
AU2004219603A1 (en) Novel compositions and methods for the treatment of immune related disease
AU2003267096B2 (en) Novel compositions and methods for the treatment of immune related diseases
US20140018250A1 (en) Compositions and methods for the treatment of immune related diseases
US20090186018A1 (en) Compositions and methods for the treatment of rheumatoid arthritis
AU2003247806B2 (en) Compositions and methods for the treatment of immune related diseases
AU2003263045A1 (en) Novel compositions and methods for the treatment of psoriasis
AU2007202846B2 (en) Compositions and methods for the treatment of immune related diseases
AU2011226945A1 (en) Compositions and methods for the treatment of immune related diseases
AU2003215353A1 (en) Compositions and methods for the treatment of immune related diseases
AU2012233034A1 (en) Novel compositions and methods for the treatment of immune related diseases

Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted