AU2003256823B9 - Methods of treating and preventing RSV, hMPV, and PIV using anti-RSV, anti-hMPV, and anti-PIV antibodies - Google Patents

Methods of treating and preventing RSV, hMPV, and PIV using anti-RSV, anti-hMPV, and anti-PIV antibodies Download PDF

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Publication number
AU2003256823B9
AU2003256823B9 AU2003256823A AU2003256823A AU2003256823B9 AU 2003256823 B9 AU2003256823 B9 AU 2003256823B9 AU 2003256823 A AU2003256823 A AU 2003256823A AU 2003256823 A AU2003256823 A AU 2003256823A AU 2003256823 B9 AU2003256823 B9 AU 2003256823B9
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AU
Australia
Prior art keywords
antigen
antibodies
rsv
protein
binding fragments
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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AU2003256823A
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English (en)
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AU2003256823B2 (en
AU2003256823A1 (en
Inventor
Ronaldus A.M. Fouchier
Peter Kiener
Albertus D. M. E. Osterhaus
James F. Young
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vironovative BV
MedImmune LLC
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Vironovative BV
MedImmune LLC
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Publication of AU2003256823A1 publication Critical patent/AU2003256823A1/en
Assigned to MEDIMMUNE, INC., VIRONOVATIVE B.V. reassignment MEDIMMUNE, INC. Request for Assignment Assignors: MEDIMMUNE, INC., VIRONOVATIVE B.V.
Assigned to MEDIMMUNE, LLC, VIRONOVATIVE B.V. reassignment MEDIMMUNE, LLC Alteration of Name(s) of Applicant(s) under S113 Assignors: MEDIMMUNE, INC., VIRONOVATIVE B.V.
Publication of AU2003256823B2 publication Critical patent/AU2003256823B2/en
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Publication of AU2003256823B9 publication Critical patent/AU2003256823B9/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1027Paramyxoviridae, e.g. respiratory syncytial virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2003256823A 2002-07-25 2003-07-25 Methods of treating and preventing RSV, hMPV, and PIV using anti-RSV, anti-hMPV, and anti-PIV antibodies Ceased AU2003256823B9 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39847502P 2002-07-25 2002-07-25
US60/398,475 2002-07-25
PCT/US2003/023376 WO2004010935A2 (en) 2002-07-25 2003-07-25 Methods of treating and preventing rsv, hmpv, and piv using anti-rsv, anti-hmpv, and anti-piv antibodies

Publications (3)

Publication Number Publication Date
AU2003256823A1 AU2003256823A1 (en) 2004-02-16
AU2003256823B2 AU2003256823B2 (en) 2008-11-06
AU2003256823B9 true AU2003256823B9 (en) 2009-01-08

Family

ID=31188405

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003256823A Ceased AU2003256823B9 (en) 2002-07-25 2003-07-25 Methods of treating and preventing RSV, hMPV, and PIV using anti-RSV, anti-hMPV, and anti-PIV antibodies

Country Status (7)

Country Link
US (2) US20040096451A1 (enExample)
EP (1) EP1534327A4 (enExample)
JP (1) JP2005533861A (enExample)
AU (1) AU2003256823B9 (enExample)
CA (1) CA2494485A1 (enExample)
TW (1) TW200501985A (enExample)
WO (1) WO2004010935A2 (enExample)

Cited By (1)

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WO2020132774A1 (es) * 2018-12-28 2020-07-02 Pontificia Universidad Católica De Chile Anticuerpo monoclonal o una porción de unión a antígeno del mismo que se une a la proteína l del virus parainfluenza humano (piv); método y kit para detectar al virus piv

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EP2327418A1 (en) 2002-02-21 2011-06-01 MedImmune, LLC Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from other viruses
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WO2008106980A2 (en) * 2007-03-06 2008-09-12 Symphogen A/S Recombinant antibodies for treatment of respiratory syncytial virus infections
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NZ630920A (en) * 2012-03-20 2017-01-27 Humabs Biomed Sa Antibodies that neutralize rsv, mpv and pvm and uses thereof
EP2836505B1 (en) * 2012-04-10 2019-01-23 The Trustees Of The University Of Pennsylvania Human respiratory syncytial virus concensus antigens, nucleic acid constructs and vaccines made thereform, and methods of using same
EA039682B1 (ru) * 2012-06-04 2022-02-28 Хумабс Биомед Са Антитела, нейтрализующие rsv, mpv и pvm, и их применения
AU2014243756B2 (en) 2013-03-13 2018-09-27 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Prefusion RSV F proteins and their use
CL2015002152A1 (es) * 2015-07-31 2016-06-03 Pontificia Universidad Católica De Chile Anticuerpos monoclonales específicos para el antígeno p del virus respiratorio sincicial humano (vrsh), producidos y secretados por hibridomas celulares, útiles para la detección y el diagnostico de la infección causada por vrsh
EP3718565B1 (en) 2015-10-22 2022-04-27 ModernaTX, Inc. Respiratory virus vaccines
CN109069611B (zh) 2016-03-29 2022-11-04 美国政府(由卫生和人类服务部的部长所代表) 取代修饰的融合前rsv f蛋白及其用途
US11103578B2 (en) 2016-12-08 2021-08-31 Modernatx, Inc. Respiratory virus nucleic acid vaccines
WO2018109220A2 (en) 2016-12-16 2018-06-21 Institute For Research In Biomedicine Novel recombinant prefusion rsv f proteins and uses thereof
EP3375876A1 (en) * 2017-03-13 2018-09-19 Evonetix Ltd Method for producing double stranded polynucleotides based on oligonucleotides with selected and different melting temperatures
MA51230A (fr) 2018-01-29 2021-05-05 Merck Sharp & Dohme Protéines f rsv stabilisées et leurs utilisations
WO2020033742A1 (en) 2018-08-08 2020-02-13 Trellis Bioscience, Llc Improved rsv passive and active vaccines
EP3848389A4 (en) * 2018-09-03 2022-04-13 Pontificia Universidad Católica De Chile SPECIFIC MONOCLONAL ANTIBODIES AGAINST HUMAN RESPIRATORY SYNCYTIAL VIRUS (HRSV) N-ANTIGEN FOR TREATMENT, DETECTION AND DIAGNOSIS OF INFECTION
US11351242B1 (en) 2019-02-12 2022-06-07 Modernatx, Inc. HMPV/hPIV3 mRNA vaccine composition
JP7274904B2 (ja) * 2019-03-26 2023-05-17 田中貴金属工業株式会社 ヒトメタニューモウイルス検出用試薬
JP2024512215A (ja) * 2021-02-12 2024-03-19 メルク・シャープ・アンド・ドーム・エルエルシー メタニューモウイルス、抗原性メタニューモウイルスタンパク質に結合する抗体、及びその使用
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020132774A1 (es) * 2018-12-28 2020-07-02 Pontificia Universidad Católica De Chile Anticuerpo monoclonal o una porción de unión a antígeno del mismo que se une a la proteína l del virus parainfluenza humano (piv); método y kit para detectar al virus piv
US12195523B2 (en) 2018-12-28 2025-01-14 Pontificia Universidad Catolica De Chile Monoclonal antibody or antigen binding fragment thereof that binds to the L protein of the human parainfluenza virus (PIV); method and kit for detecting PIV

Also Published As

Publication number Publication date
AU2003256823B2 (en) 2008-11-06
WO2004010935A3 (en) 2004-11-11
US20040096451A1 (en) 2004-05-20
TW200501985A (en) 2005-01-16
US20100278813A1 (en) 2010-11-04
EP1534327A2 (en) 2005-06-01
AU2003256823A1 (en) 2004-02-16
JP2005533861A (ja) 2005-11-10
WO2004010935A2 (en) 2004-02-05
CA2494485A1 (en) 2004-02-05
EP1534327A4 (en) 2006-08-23

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