CA2494485A1 - Methods of treating and preventing rsv, hmpv, and piv using anti-rsv, anti-hmpv, and anti-piv antibodies - Google Patents
Methods of treating and preventing rsv, hmpv, and piv using anti-rsv, anti-hmpv, and anti-piv antibodies Download PDFInfo
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- CA2494485A1 CA2494485A1 CA002494485A CA2494485A CA2494485A1 CA 2494485 A1 CA2494485 A1 CA 2494485A1 CA 002494485 A CA002494485 A CA 002494485A CA 2494485 A CA2494485 A CA 2494485A CA 2494485 A1 CA2494485 A1 CA 2494485A1
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- antigen
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1027—Paramyxoviridae, e.g. respiratory syncytial virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
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| US39847502P | 2002-07-25 | 2002-07-25 | |
| US60/398,475 | 2002-07-25 | ||
| PCT/US2003/023376 WO2004010935A2 (en) | 2002-07-25 | 2003-07-25 | Methods of treating and preventing rsv, hmpv, and piv using anti-rsv, anti-hmpv, and anti-piv antibodies |
Publications (1)
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| CA2494485A1 true CA2494485A1 (en) | 2004-02-05 |
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| EP (1) | EP1534327A4 (enExample) |
| JP (1) | JP2005533861A (enExample) |
| AU (1) | AU2003256823B9 (enExample) |
| CA (1) | CA2494485A1 (enExample) |
| TW (1) | TW200501985A (enExample) |
| WO (1) | WO2004010935A2 (enExample) |
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| US6855493B2 (en) | 2000-11-28 | 2005-02-15 | Medimmune, Inc. | Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment |
| WO2002057302A2 (en) | 2001-01-19 | 2002-07-25 | Vironovative B.V. | A virus causing respiratory tract illness in susceptible mammals |
| EP2327418A1 (en) | 2002-02-21 | 2011-06-01 | MedImmune, LLC | Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from other viruses |
| US20050152899A1 (en) * | 2002-05-10 | 2005-07-14 | Kinch Michael S. | EphA2 agonistic monoclonal antibodies and methods of use thereof |
| EP1575509B1 (en) * | 2002-05-10 | 2011-10-26 | Purdue Research Foundation | Epha2 agonistic monoclonal antibodies and methods of use thereof |
| WO2003094859A2 (en) * | 2002-05-10 | 2003-11-20 | Medimmune, Inc. | Epha2 monoclonal antibodies and methods of use thereof |
| US7132100B2 (en) | 2002-06-14 | 2006-11-07 | Medimmune, Inc. | Stabilized liquid anti-RSV antibody formulations |
| JP2006524693A (ja) * | 2003-04-11 | 2006-11-02 | メディミューン，インコーポレーテッド | ＥｐｈＡ２および非腫瘍性過増殖性細胞障害 |
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| US20060083741A1 (en) * | 2004-10-08 | 2006-04-20 | Hoffman Rebecca S | Treatment of respiratory syncytial virus (RSV) infection |
| US20060115485A1 (en) * | 2004-10-29 | 2006-06-01 | Medimmune, Inc. | Methods of preventing and treating RSV infections and related conditions |
| WO2006110214A2 (en) * | 2005-04-08 | 2006-10-19 | Medimmune, Inc. | Antibodies against mammalian metapneumovirus |
| JP2008546805A (ja) | 2005-06-23 | 2008-12-25 | メディミューン，エルエルシー | 最適な凝集および断片化プロフィールを有する抗体製剤 |
| US20090053790A1 (en) | 2006-01-31 | 2009-02-26 | Ishihara Sangyo Kaisha, Ltd. | Polypeptide Having Affinity for Envelope Virus Constituent and Use Thereof in Transferring Substance Into Cell |
| KR20080113223A (ko) * | 2006-03-06 | 2008-12-29 | 심포젠 에이/에스 | 호흡기세포 융합 바이러스 감염 치료용 재조합 폴리클로날 항체 |
| WO2008106980A2 (en) * | 2007-03-06 | 2008-09-12 | Symphogen A/S | Recombinant antibodies for treatment of respiratory syncytial virus infections |
| EP1997830A1 (en) | 2007-06-01 | 2008-12-03 | AIMM Therapeutics B.V. | RSV specific binding molecules and means for producing them |
| MX2012000036A (es) * | 2009-06-24 | 2012-02-28 | Glaxosmithkline Biolog Sa | Vacuna. |
| US8840889B2 (en) | 2009-08-13 | 2014-09-23 | The Johns Hopkins University | Methods of modulating immune function |
| US8568726B2 (en) | 2009-10-06 | 2013-10-29 | Medimmune Limited | RSV specific binding molecule |
| NZ703035A (en) | 2010-07-09 | 2016-06-24 | Crucell Holland Bv | Anti-human respiratory syncytial virus (rsv) antibodies and methods of use |
| WO2012089231A1 (en) * | 2010-12-30 | 2012-07-05 | Okairòs Ag | Paramyxovirus vaccines |
| NZ630920A (en) * | 2012-03-20 | 2017-01-27 | Humabs Biomed Sa | Antibodies that neutralize rsv, mpv and pvm and uses thereof |
| EP2836505B1 (en) * | 2012-04-10 | 2019-01-23 | The Trustees Of The University Of Pennsylvania | Human respiratory syncytial virus concensus antigens, nucleic acid constructs and vaccines made thereform, and methods of using same |
| EA039682B1 (ru) * | 2012-06-04 | 2022-02-28 | Хумабс Биомед Са | Антитела, нейтрализующие rsv, mpv и pvm, и их применения |
| AU2014243756B2 (en) | 2013-03-13 | 2018-09-27 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Prefusion RSV F proteins and their use |
| CL2015002152A1 (es) * | 2015-07-31 | 2016-06-03 | Pontificia Universidad Católica De Chile | Anticuerpos monoclonales específicos para el antígeno p del virus respiratorio sincicial humano (vrsh), producidos y secretados por hibridomas celulares, útiles para la detección y el diagnostico de la infección causada por vrsh |
| EP3718565B1 (en) | 2015-10-22 | 2022-04-27 | ModernaTX, Inc. | Respiratory virus vaccines |
| CN109069611B (zh) | 2016-03-29 | 2022-11-04 | 美国政府(由卫生和人类服务部的部长所代表) | 取代修饰的融合前rsv f蛋白及其用途 |
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| WO2018109220A2 (en) | 2016-12-16 | 2018-06-21 | Institute For Research In Biomedicine | Novel recombinant prefusion rsv f proteins and uses thereof |
| EP3375876A1 (en) * | 2017-03-13 | 2018-09-19 | Evonetix Ltd | Method for producing double stranded polynucleotides based on oligonucleotides with selected and different melting temperatures |
| MA51230A (fr) | 2018-01-29 | 2021-05-05 | Merck Sharp & Dohme | Protéines f rsv stabilisées et leurs utilisations |
| WO2020033742A1 (en) | 2018-08-08 | 2020-02-13 | Trellis Bioscience, Llc | Improved rsv passive and active vaccines |
| EP3848389A4 (en) * | 2018-09-03 | 2022-04-13 | Pontificia Universidad Católica De Chile | SPECIFIC MONOCLONAL ANTIBODIES AGAINST HUMAN RESPIRATORY SYNCYTIAL VIRUS (HRSV) N-ANTIGEN FOR TREATMENT, DETECTION AND DIAGNOSIS OF INFECTION |
| CL2018003869A1 (es) | 2018-12-28 | 2021-01-15 | Univ Pontificia Catolica Chile | Anticuerpos monoclonales específicos para la proteína quimérica l del virus de la parainfluenza humana (piv), secuencias nucleotídicas; método y kit de diagnóstico de infección producida por piv |
| US11351242B1 (en) | 2019-02-12 | 2022-06-07 | Modernatx, Inc. | HMPV/hPIV3 mRNA vaccine composition |
| JP7274904B2 (ja) * | 2019-03-26 | 2023-05-17 | 田中貴金属工業株式会社 | ヒトメタニューモウイルス検出用試薬 |
| JP2024512215A (ja) * | 2021-02-12 | 2024-03-19 | メルク・シャープ・アンド・ドーム・エルエルシー | メタニューモウイルス、抗原性メタニューモウイルスタンパク質に結合する抗体、及びその使用 |
| US20230174632A1 (en) * | 2021-12-08 | 2023-06-08 | IgGenix, Inc. | Combinations for allergy therapy |
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| JP2006524511A (ja) * | 2003-04-25 | 2006-11-02 | メッドイミューン バクシーンズ，インコーポレイティド | メタニューモウイルス由来の異種抗原を含む組換えパラインフルエンザウイルス発現系およびワクチン |
| EP2494987A1 (en) * | 2003-04-25 | 2012-09-05 | MedImmune Vaccines, Inc. | Metapneumovirus strains and their use in vaccine formulations and as vectors for expression of antigenic sequences and methods for propagating virus |
| KR20070110924A (ko) * | 2005-03-10 | 2007-11-20 | 메드이뮨 백신즈 인코포레이티드 | 메타뉴모바이러스주 및 항원성 서열의 발현용 벡터 및 백신제제로서의 이의 용도 및 바이러스의 증식 방법 |
| WO2006110214A2 (en) * | 2005-04-08 | 2006-10-19 | Medimmune, Inc. | Antibodies against mammalian metapneumovirus |
-
2003
- 2003-07-25 TW TW092120397A patent/TW200501985A/zh unknown
- 2003-07-25 US US10/628,088 patent/US20040096451A1/en not_active Abandoned
- 2003-07-25 JP JP2004524853A patent/JP2005533861A/ja active Pending
- 2003-07-25 AU AU2003256823A patent/AU2003256823B9/en not_active Ceased
- 2003-07-25 WO PCT/US2003/023376 patent/WO2004010935A2/en not_active Ceased
- 2003-07-25 CA CA002494485A patent/CA2494485A1/en not_active Abandoned
- 2003-07-25 EP EP03771876A patent/EP1534327A4/en not_active Withdrawn
-
2007
- 2007-12-11 US US12/001,458 patent/US20100278813A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003256823B2 (en) | 2008-11-06 |
| WO2004010935A3 (en) | 2004-11-11 |
| US20040096451A1 (en) | 2004-05-20 |
| TW200501985A (en) | 2005-01-16 |
| AU2003256823B9 (en) | 2009-01-08 |
| US20100278813A1 (en) | 2010-11-04 |
| EP1534327A2 (en) | 2005-06-01 |
| AU2003256823A1 (en) | 2004-02-16 |
| JP2005533861A (ja) | 2005-11-10 |
| WO2004010935A2 (en) | 2004-02-05 |
| EP1534327A4 (en) | 2006-08-23 |
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| Date | Code | Title | Description |
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| EEER | Examination request | ||
| FZDE | Discontinued | ||
| FZDE | Discontinued |
Effective date: 20100726 |