AU2003248558B8 - Method of treating diabetes - Google Patents
Method of treating diabetes Download PDFInfo
- Publication number
- AU2003248558B8 AU2003248558B8 AU2003248558A AU2003248558A AU2003248558B8 AU 2003248558 B8 AU2003248558 B8 AU 2003248558B8 AU 2003248558 A AU2003248558 A AU 2003248558A AU 2003248558 A AU2003248558 A AU 2003248558A AU 2003248558 B8 AU2003248558 B8 AU 2003248558B8
- Authority
- AU
- Australia
- Prior art keywords
- lower alkyl
- diabetic
- mammal
- together form
- independently hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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- 238000000034 method Methods 0.000 title claims description 88
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- 239000001257 hydrogen Substances 0.000 claims description 103
- 229910052739 hydrogen Inorganic materials 0.000 claims description 103
- -1 aminocarbonylmethyl Chemical group 0.000 claims description 98
- 150000001875 compounds Chemical class 0.000 claims description 94
- 239000000203 mixture Substances 0.000 claims description 85
- XKLMZUWKNUAPSZ-UHFFFAOYSA-N N-(2,6-dimethylphenyl)-2-{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl}acetamide Chemical group COC1=CC=CC=C1OCC(O)CN1CCN(CC(=O)NC=2C(=CC=CC=2C)C)CC1 XKLMZUWKNUAPSZ-UHFFFAOYSA-N 0.000 claims description 84
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Bioinformatics & Cheminformatics (AREA)
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- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
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| US38278102P | 2002-05-21 | 2002-05-21 | |
| US60/382,781 | 2002-05-21 | ||
| US45933203P | 2003-03-31 | 2003-03-31 | |
| US60/459,332 | 2003-03-31 | ||
| PCT/US2003/016277 WO2003099281A2 (en) | 2002-05-21 | 2003-05-21 | Administration of a partial fatty acid inhibitor such as ranolazine for the treatment of diabetes |
Publications (3)
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| AU2003248558A1 AU2003248558A1 (en) | 2003-12-12 |
| AU2003248558B2 AU2003248558B2 (en) | 2009-03-12 |
| AU2003248558B8 true AU2003248558B8 (en) | 2009-07-09 |
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| AU2003248558A Ceased AU2003248558B8 (en) | 2002-05-21 | 2003-05-21 | Method of treating diabetes |
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Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8822473B2 (en) | 2002-05-21 | 2014-09-02 | Gilead Sciences, Inc. | Method of treating diabetes |
| CA2486712C (en) * | 2002-05-21 | 2012-01-03 | Cv Therapeutics, Inc. | Method of treating diabetes |
| CA2593593A1 (en) * | 2005-01-06 | 2006-07-13 | Cv Therapeutics, Inc. | Sustained release pharmaceutical formulations comprising ranolazine |
| JP2010518169A (ja) * | 2007-02-13 | 2010-05-27 | ギリアード・パロ・アルト・インコーポレイテッド | 心血管疾患の処置のためのラノラジンの使用 |
| WO2008101008A1 (en) * | 2007-02-13 | 2008-08-21 | Cv Therapeutics, Inc. | Use of ranolazine for the treatment of coronary microvascular diseases |
| US20090111826A1 (en) * | 2007-02-13 | 2009-04-30 | Louis Lange | Use of ranolazine for the treatment of cardiovascular diseases |
| JP2010518171A (ja) * | 2007-02-13 | 2010-05-27 | ギリアード・パロ・アルト・インコーポレイテッド | 非冠微小血管疾患の処置のためのラノラジンの使用 |
| US20080233191A1 (en) * | 2007-03-22 | 2008-09-25 | Brent Blackburn | Use of ranolazine for elevated brain-type natriuretic peptide |
| CA2681444A1 (en) * | 2007-04-12 | 2008-10-23 | Cv Therapeutics, Inc. | Ranolazine for enhancing insulin secretion |
| RU2442585C2 (ru) * | 2007-05-31 | 2012-02-20 | Си Ви Терапьютикс, Инк. | Способ лечения диабета |
| ES2402675T3 (es) * | 2007-05-31 | 2013-05-07 | Gilead Palo Alto, Inc. | Ranolazina para el péptido natriurético de tipo cerebral a niveles elevados |
| KR20100038322A (ko) * | 2007-05-31 | 2010-04-14 | 씨브이 쎄러퓨틱스, 인코포레이티드 | 당뇨병 치료 방법 |
| US20090012103A1 (en) * | 2007-07-05 | 2009-01-08 | Matthew Abelman | Substituted heterocyclic compounds |
| AU2009212254A1 (en) * | 2008-02-06 | 2009-08-13 | Cv Therapeutics, Inc. | Use of Ranolazine for treating pain |
| US20110280941A1 (en) * | 2008-12-11 | 2011-11-17 | Mefford Scientific, Llc | Compositions of proton pump inhibitors and insulin secretagogues, and methods of their use to treat diabetes |
| CA2761771A1 (en) * | 2009-05-14 | 2010-11-18 | Gilead Sciences, Inc. | Ranolazine for the treatment of cns disorders |
| JO3183B1 (ar) * | 2010-01-29 | 2018-03-08 | Regeneron Pharma | طرق لمعالجة أمراض المناعة الذاتية مضادات dll4 |
| TW201717919A (zh) | 2015-07-02 | 2017-06-01 | 國際藥品股份公司 | 雷諾多重壓縮錠劑 |
| WO2018001582A1 (en) | 2016-06-30 | 2018-01-04 | Interquim, S.A. | Ranolazine multiple compressed tablets |
| CN110812344A (zh) * | 2019-12-17 | 2020-02-21 | 卓和药业集团有限公司 | 一种治疗糖尿病合并心绞痛的药物组合物及制备方法 |
| GR1010510B (el) * | 2022-06-07 | 2023-07-20 | Ελπεν Α.Ε. Φαρμακευτικη Βιομηχανια, | Στερεες φαρμακοτεχνικες μορφες παρατεταμενης αποδεσμευσης ρανολαζινης |
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- 2003-05-21 RU RU2004133670/14A patent/RU2320343C2/ru not_active IP Right Cessation
- 2003-05-21 US US10/443,314 patent/US20040063717A1/en not_active Abandoned
- 2003-05-21 WO PCT/US2003/016277 patent/WO2003099281A2/en not_active Ceased
- 2003-05-21 BR BR0311161-0A patent/BR0311161A/pt not_active Application Discontinuation
- 2003-05-21 EP EP10011229A patent/EP2332540A1/en not_active Withdrawn
- 2003-05-21 ES ES03755446.6T patent/ES2523873T3/es not_active Expired - Lifetime
- 2003-05-21 AU AU2003248558A patent/AU2003248558B8/en not_active Ceased
- 2003-05-21 IL IL16530403A patent/IL165304A0/xx unknown
- 2003-05-21 NZ NZ536678A patent/NZ536678A/en not_active IP Right Cessation
- 2003-05-21 CN CNB038113236A patent/CN100551370C/zh not_active Expired - Fee Related
- 2003-05-21 EP EP03755446.6A patent/EP1505977B1/en not_active Expired - Lifetime
- 2003-05-21 KR KR1020047018803A patent/KR101030943B1/ko not_active Expired - Fee Related
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- 2004-11-18 IL IL165304A patent/IL165304A/en active IP Right Grant
- 2004-11-19 ZA ZA2004/09331A patent/ZA200409331B/en unknown
- 2004-12-20 NO NO20045554A patent/NO330336B1/no not_active IP Right Cessation
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2010
- 2010-04-07 US US12/755,931 patent/US8314104B2/en not_active Expired - Fee Related
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- 2011-06-28 IL IL213809A patent/IL213809A0/en unknown
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- 2012-10-18 US US13/655,252 patent/US8883750B2/en not_active Expired - Fee Related
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| FR2805463A1 (fr) * | 2000-02-25 | 2001-08-31 | Adir | UTILISATION DE LA TRIMETAZIDINE POUR L'OBTENTION DE COMPOSITIONS PHARMACEUTIQUES DESTINEES A INHIBER L'ACYL-CoA ACETYLTRANSFERASE |
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