AU2003244515A1 - Albumin-fused anti-angiogenesis peptides - Google Patents

Albumin-fused anti-angiogenesis peptides Download PDF

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Publication number
AU2003244515A1
AU2003244515A1 AU2003244515A AU2003244515A AU2003244515A1 AU 2003244515 A1 AU2003244515 A1 AU 2003244515A1 AU 2003244515 A AU2003244515 A AU 2003244515A AU 2003244515 A AU2003244515 A AU 2003244515A AU 2003244515 A1 AU2003244515 A1 AU 2003244515A1
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AU
Australia
Prior art keywords
albumin
fusion protein
albumin fusion
fragment
angiogenesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003244515A
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English (en)
Inventor
Ilhan Celik
Hans-Peter Hauser
Joanna Hay
Oliver Kisker
Peter Mertins
Darrell Sleep
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Albumedix Ltd
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Novozymes Delta Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes Delta Ltd filed Critical Novozymes Delta Ltd
Publication of AU2003244515A1 publication Critical patent/AU2003244515A1/en
Assigned to NOVOZYMES DELTA LIMITED reassignment NOVOZYMES DELTA LIMITED Request for Assignment Assignors: DELTA BIOTECHNOLOGY LIMITED
Abandoned legal-status Critical Current

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    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
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    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38Albumins
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    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/643Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/765Serum albumin, e.g. HSA
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    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
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    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
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    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
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    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/26Endoribonucleases producing 5'-phosphomonoesters (3.1.26)
    • C12Y301/26003Ribonuclease III (3.1.26.3)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
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AU2003244515A 2002-02-07 2003-02-07 Albumin-fused anti-angiogenesis peptides Abandoned AU2003244515A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35554702P 2002-02-07 2002-02-07
US60/355,547 2002-02-07
PCT/IB2003/000433 WO2003066085A1 (en) 2002-02-07 2003-02-07 Albumin-fused anti-angiogenesis peptides

Publications (1)

Publication Number Publication Date
AU2003244515A1 true AU2003244515A1 (en) 2003-09-02

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ID=27734531

Family Applications (5)

Application Number Title Priority Date Filing Date
AU2003244515A Abandoned AU2003244515A1 (en) 2002-02-07 2003-02-07 Albumin-fused anti-angiogenesis peptides
AU2003244516A Abandoned AU2003244516A1 (en) 2002-02-07 2003-02-07 Hiv inhibiting proteins
AU2003210885A Ceased AU2003210885B2 (en) 2002-02-07 2003-02-07 Albumin-fused kunitz domain peptides
AU2008264153A Abandoned AU2008264153A1 (en) 2002-02-07 2008-12-23 HIV inhibiting proteins
AU2009212820A Expired - Fee Related AU2009212820B2 (en) 2002-02-07 2009-08-27 Albumin-fused kunitz domain peptides

Family Applications After (4)

Application Number Title Priority Date Filing Date
AU2003244516A Abandoned AU2003244516A1 (en) 2002-02-07 2003-02-07 Hiv inhibiting proteins
AU2003210885A Ceased AU2003210885B2 (en) 2002-02-07 2003-02-07 Albumin-fused kunitz domain peptides
AU2008264153A Abandoned AU2008264153A1 (en) 2002-02-07 2008-12-23 HIV inhibiting proteins
AU2009212820A Expired - Fee Related AU2009212820B2 (en) 2002-02-07 2009-08-27 Albumin-fused kunitz domain peptides

Country Status (10)

Country Link
US (4) US20060122374A1 (https=)
EP (4) EP1572930A4 (https=)
JP (4) JP2005538932A (https=)
KR (4) KR20110014661A (https=)
CN (3) CN1646154B (https=)
AU (5) AU2003244515A1 (https=)
CA (3) CA2475382A1 (https=)
NZ (3) NZ579419A (https=)
WO (3) WO2003066824A2 (https=)
ZA (3) ZA200406124B (https=)

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US6057287A (en) 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
ES2229236T3 (es) 1994-01-11 2005-04-16 Dyax Corporation Inhibidores de la plasmina humana derivados de los dominios de kunitz.
WO2003103475A2 (en) 2002-06-07 2003-12-18 Dyax Corp. Prevention and reduction of blood loss
US7153829B2 (en) 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
GB0217033D0 (en) 2002-07-23 2002-08-28 Delta Biotechnology Ltd Gene and polypeptide sequences
JP2005537006A (ja) 2002-08-28 2005-12-08 ダイアックス、コープ 臓器及び組織の保存方法
JP2006517400A (ja) 2002-12-19 2006-07-27 ネクター セラピューティクス アラバマ,コーポレイション シアノビリン変異体−ポリマー接合体
CA2513213C (en) * 2003-01-22 2013-07-30 Human Genome Sciences, Inc. Albumin fusion proteins
US6989369B2 (en) 2003-02-07 2006-01-24 Dyax Corp. Kunitz domain peptides
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