AU2003243587B2 - Compounds useful for the treatment of cancer, compositions thereof and methods therewith - Google Patents

Compounds useful for the treatment of cancer, compositions thereof and methods therewith Download PDF

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Publication number
AU2003243587B2
AU2003243587B2 AU2003243587A AU2003243587A AU2003243587B2 AU 2003243587 B2 AU2003243587 B2 AU 2003243587B2 AU 2003243587 A AU2003243587 A AU 2003243587A AU 2003243587 A AU2003243587 A AU 2003243587A AU 2003243587 B2 AU2003243587 B2 AU 2003243587B2
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AU
Australia
Prior art keywords
substituted
branched
unbranched
alkyl
independently
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2003243587A
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English (en)
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AU2003243587A1 (en
Inventor
Jeffrey Mckenna
Frank Mercurio
Veronique Plantevin
Weilin Xie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Signal Pharmaceuticals LLC
Original Assignee
Signal Pharmaceuticals LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Signal Pharmaceuticals LLC filed Critical Signal Pharmaceuticals LLC
Publication of AU2003243587A1 publication Critical patent/AU2003243587A1/en
Application granted granted Critical
Publication of AU2003243587B2 publication Critical patent/AU2003243587B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
AU2003243587A 2002-06-17 2003-06-17 Compounds useful for the treatment of cancer, compositions thereof and methods therewith Ceased AU2003243587B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US38946102P 2002-06-17 2002-06-17
US60/389,461 2002-06-17
US10/463,009 2003-06-16
US10/463,009 US7037936B2 (en) 2002-06-17 2003-06-16 Compounds useful for the treatment of cancer, compositions thereof and methods therewith
PCT/US2003/018905 WO2003105774A2 (en) 2002-06-17 2003-06-17 Compounds useful for the treatment of cancer, compositions thereof and methods therewith

Publications (2)

Publication Number Publication Date
AU2003243587A1 AU2003243587A1 (en) 2003-12-31
AU2003243587B2 true AU2003243587B2 (en) 2008-02-28

Family

ID=29740147

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003243587A Ceased AU2003243587B2 (en) 2002-06-17 2003-06-17 Compounds useful for the treatment of cancer, compositions thereof and methods therewith

Country Status (10)

Country Link
US (2) US7037936B2 (enExample)
EP (1) EP1551388A4 (enExample)
JP (1) JP2006515560A (enExample)
CN (1) CN1674888A (enExample)
AU (1) AU2003243587B2 (enExample)
CA (1) CA2488891A1 (enExample)
IL (1) IL165839A0 (enExample)
MX (1) MXPA04012675A (enExample)
NZ (1) NZ537653A (enExample)
WO (1) WO2003105774A2 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050100529A1 (en) * 2003-11-06 2005-05-12 Zeldis Jerome B. Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of asbestos-related diseases and disorders
US8175808B2 (en) * 2005-04-01 2012-05-08 Sloan Kettering Institute For Cancer Research Method for determining disease treatment duration
CA2632968A1 (en) 2005-12-02 2007-06-07 Isis Pharmaceuticals, Inc. Antibacterial 4,5-substituted aminoglycoside analogs having multiple substituents
WO2010030704A2 (en) 2008-09-10 2010-03-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010030690A1 (en) 2008-09-10 2010-03-18 Isis Pharmaceuticals, Inc. Antibacterial 4,6-substituted 6', 6" and 1 modified aminoglycoside analogs
WO2010042850A1 (en) 2008-10-09 2010-04-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010042851A1 (en) 2008-10-09 2010-04-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
EP2486044A2 (en) 2009-10-09 2012-08-15 Achaogen, Inc. Antibacterial aminoglycoside analogs
CN102985405B (zh) * 2010-07-02 2016-07-06 Aska制药株式会社 杂环化合物及p27Kip1分解抑制剂
TW201304784A (zh) 2010-11-17 2013-02-01 Achaogen Inc 抗菌性胺基糖苷類似物
WO2012075232A1 (en) * 2010-12-04 2012-06-07 Trevena, Inc. Opioid receptor ligands and methods of using and making the same
JP2024523237A (ja) 2021-06-18 2024-06-28 ホンジーン バイオテック コーポレイション 官能化されたn-アセチルガラクトサミンヌクレオシド
WO2023034719A1 (en) 2021-08-30 2023-03-09 Hongene Biotech Corporation Functionalized n-acetylgalactosamine analogs
EP4448540A1 (en) 2021-12-15 2024-10-23 Hongene Biotech Corporation Functionalized n-acetylgalactosamine analogs
WO2024118503A1 (en) 2022-11-28 2024-06-06 Hongene Biotech Corporation Functionalized n-acetylgalactosamine analogs

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3328249A (en) * 1965-06-21 1967-06-27 Sterling Drug Inc Process for counteracting depressive states
US3485873A (en) * 1966-12-21 1969-12-23 Sterling Drug Inc N-benzyl-n-methyl-omega-phenyl-omega-cycloalkyl-lower-alkylamines
GB9201755D0 (en) 1992-01-28 1992-03-11 British Bio Technology Compounds
CA2341064A1 (en) 1998-08-28 2000-03-09 New York University Novel ubiquitin ligases as therapeutic targets
DE69943222D1 (de) 1998-12-10 2011-04-07 Signal Pharm Llc Menschliche ubiqutin ligase e3. verwendung für die modulation von nf-kappa b
US20010044445A1 (en) * 1999-04-08 2001-11-22 Bamaung Nwe Y. Azole inhibitors of cytokine production
WO2002055665A2 (en) 2001-01-05 2002-07-18 Univ New York Methods to identify compounds useful for the treatment of proliferative and differentiative disorders
MXPA04011930A (es) * 2002-05-31 2005-03-31 Yamanouchi Pharma Co Ltd Derivados de tetrahidropirano.

Also Published As

Publication number Publication date
US20060142352A1 (en) 2006-06-29
US7037936B2 (en) 2006-05-02
JP2006515560A (ja) 2006-06-01
AU2003243587A1 (en) 2003-12-31
US20060030617A1 (en) 2006-02-09
IL165839A0 (en) 2006-01-15
EP1551388A2 (en) 2005-07-13
EP1551388A4 (en) 2009-07-15
CA2488891A1 (en) 2003-12-24
MXPA04012675A (es) 2005-08-15
WO2003105774A2 (en) 2003-12-24
CN1674888A (zh) 2005-09-28
NZ537653A (en) 2007-09-28
WO2003105774A3 (en) 2004-08-12

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MK14 Patent ceased section 143(a) (annual fees not paid) or expired