AU2003225636A1 - Immunizing composition and method for inducing an immune response against the ss-secretase cleavage site of amyloid precursor protein - Google Patents
Immunizing composition and method for inducing an immune response against the ss-secretase cleavage site of amyloid precursor proteinInfo
- Publication number
- AU2003225636A1 AU2003225636A1 AU2003225636A AU2003225636A AU2003225636A1 AU 2003225636 A1 AU2003225636 A1 AU 2003225636A1 AU 2003225636 A AU2003225636 A AU 2003225636A AU 2003225636 A AU2003225636 A AU 2003225636A AU 2003225636 A1 AU2003225636 A1 AU 2003225636A1
- Authority
- AU
- Australia
- Prior art keywords
- inducing
- immune response
- cleavage site
- response against
- precursor protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0007—Nervous system antigens; Prions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/64—Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units
- A61K2039/645—Dendrimers; Multiple antigen peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36134402P | 2002-03-05 | 2002-03-05 | |
| US60/361,344 | 2002-03-05 | ||
| PCT/US2003/006388 WO2003076455A2 (en) | 2002-03-05 | 2003-03-04 | Immunizing composition and method for inducing an immune response against the ss-secretase cleavage site of amyloid precursor protein |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2003225636A8 AU2003225636A8 (en) | 2003-09-22 |
| AU2003225636A1 true AU2003225636A1 (en) | 2003-09-22 |
Family
ID=27805031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003225636A Abandoned AU2003225636A1 (en) | 2002-03-05 | 2003-03-04 | Immunizing composition and method for inducing an immune response against the ss-secretase cleavage site of amyloid precursor protein |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US7494655B2 (enExample) |
| EP (2) | EP2292247A3 (enExample) |
| JP (3) | JP2005532276A (enExample) |
| AU (1) | AU2003225636A1 (enExample) |
| CA (1) | CA2477675C (enExample) |
| ES (1) | ES2392247T3 (enExample) |
| IL (3) | IL163812A0 (enExample) |
| WO (1) | WO2003076455A2 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1398019A1 (de) | 2002-09-13 | 2004-03-17 | Cognis France S.A. | Verfahren zum Schutz und zur Modulation von Dermal Epidermal Junctions |
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| WO2005033278A2 (en) * | 2003-09-30 | 2005-04-14 | Ludwig Institute For Cancer Research | In vivo efficacy of ny-eso-1 plus iscom |
| BRPI0516674A (pt) * | 2004-10-28 | 2008-09-16 | Sanko Junyaku Kk | método de análise de mal de alzheimer e reagente de diagnóstico |
| JP5213718B2 (ja) | 2005-10-18 | 2013-06-19 | スターファーマ・プロプライエタリー・リミテッド | 殺微生物性デンドリマー組成物のデリバリーシステム |
| HUE031341T2 (hu) | 2005-10-25 | 2017-07-28 | Starpharma Pty Ltd | Ellenõrzött sztöchiometriájú makromolekuláris vegyületek |
| PL1976877T5 (pl) | 2005-11-30 | 2017-09-29 | Abbvie Inc | Przeciwciała monoklonalne przeciwko białku amyloidu beta oraz ich zastosowania |
| RU2442793C2 (ru) | 2005-11-30 | 2012-02-20 | Эбботт Лэборетриз | АНТИТЕЛА ПРОТИВ ГЛОБУЛОМЕРА Аβ, ИХ АНТИГЕНСВЯЗЫВАЮЩИЕ ЧАСТИ, СООТВЕТСТВУЮЩИЕ ГИБРИДОМЫ, НУКЛЕИНОВЫЕ КИСЛОТЫ, ВЕКТОРЫ, КЛЕТКИ-ХОЗЯЕВА, СПОСОБЫ ПОЛУЧЕНИЯ УКАЗАННЫХ АНТИТЕЛ, КОМПОЗИЦИИ, СОДЕРЖАЩИЕ УКАЗАННЫЕ АНТИТЕЛА, ПРИМЕНЕНИЯ УКАЗАННЫХ АНТИТЕЛ И СПОСОБЫ ИСПОЛЬЗОВАНИЯ УКАЗАННЫХ АНТИТЕЛ |
| WO2007082331A1 (en) | 2006-01-20 | 2007-07-26 | Starpharma Pty Limited | Modified macromolecule |
| AU2007229268B2 (en) | 2006-03-22 | 2013-01-10 | Starpharma Pty Limited | Contraceptive composition |
| US20090324554A1 (en) * | 2006-07-21 | 2009-12-31 | Ramot At Tel Aviv University Ltd. | Method for inhibiting or treating a disease associated with intracellular formation of protein fibrillar or aggregates |
| WO2008017125A1 (en) | 2006-08-11 | 2008-02-14 | Starpharma Pty Ltd | Targeted polylysine dendrimer therapeutic agent |
| EP2091959A4 (en) | 2006-11-28 | 2010-05-05 | Alzhyme Pty Ltd | IMPROVED PEPTIDE COMPOSITION |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| US8895004B2 (en) | 2007-02-27 | 2014-11-25 | AbbVie Deutschland GmbH & Co. KG | Method for the treatment of amyloidoses |
| WO2009041501A1 (ja) | 2007-09-27 | 2009-04-02 | Virus Ikagaku Kenkyusho Inc. | ヘルペスウイルスの潜伏感染に関与する因子及びその利用 |
| GB0720912D0 (en) | 2007-10-25 | 2007-12-05 | Univ Cardiff | Monoclonal Anitbody for APP |
| KR101397554B1 (ko) * | 2007-11-09 | 2014-05-21 | 재단법인서울대학교산학협력재단 | 치매(알츠하이머 병)의 진단, 예방, 치료제 및 이들의스크리닝 방법 |
| CA2707859A1 (en) | 2007-12-11 | 2009-06-18 | Glaxo Group Limited | Antigen binding proteins specific against beta amyloid |
| WO2009124119A2 (en) * | 2008-04-01 | 2009-10-08 | The Trustes of Columbia University in the City of New York | Phosphodiesterase inhibitors and uses thereof |
| WO2009155538A1 (en) * | 2008-06-20 | 2009-12-23 | Merck & Co., Inc. | Compositions and methods of depleting amyloid-beta peptides from cerebrospinal fluid to treat alzheimer's disease |
| AR073295A1 (es) | 2008-09-16 | 2010-10-28 | Genentech Inc | Metodos para tratar la esclerosis multiple progresiva. articulo de fabricacion. |
| AU2009316326A1 (en) * | 2008-11-24 | 2010-05-27 | Ramot At Tel-Aviv University Ltd. | Method for treating Parkinson' s disease using filamentous bacteriophage |
| JP2012513464A (ja) | 2008-12-23 | 2012-06-14 | ザ トラスティーズ オブ コロンビア ユニヴァーシティ イン ザ シティ オブ ニューヨーク | ホスホジエステラーゼ阻害剤及びその使用 |
| WO2011031720A1 (en) * | 2009-09-11 | 2011-03-17 | Arizona Board Of Regents Acting For And On Behalf Of Arizona State University | Bispecific nanobodies as a therapeutic for alzheimer's disease |
| WO2011130377A2 (en) | 2010-04-15 | 2011-10-20 | Abbott Laboratories | Amyloid-beta binding proteins |
| US9062101B2 (en) | 2010-08-14 | 2015-06-23 | AbbVie Deutschland GmbH & Co. KG | Amyloid-beta binding proteins |
| WO2015199247A1 (ja) * | 2014-06-27 | 2015-12-30 | 日本たばこ産業株式会社 | 気分障害を診断、治療又は予防する方法 |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| CN106349334A (zh) * | 2015-07-15 | 2017-01-25 | 韩震 | 一种多肽化合物及其制备方法与应用 |
| JP6641387B2 (ja) | 2015-12-28 | 2020-02-05 | 日本たばこ産業株式会社 | 融合タンパク質及びその利用 |
| CN111201030B (zh) | 2017-07-25 | 2024-11-01 | 真和制药有限公司 | 通过阻断tim-3和其配体的相互作用治疗癌症 |
| KR20210124308A (ko) | 2019-01-30 | 2021-10-14 | 트루바인딩 아이엔씨. | 항-gal3 항체 및 이의 용도 |
| MX2022014786A (es) | 2020-05-26 | 2023-01-16 | Truebinding Inc | Metodos para tratar enfermedades inflamatorias mediante el bloqueo de galectina-3. |
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| US4376861A (en) | 1976-06-23 | 1983-03-15 | The Dow Chemical Company | Method for preparing 2-alkenyl-2-oxazolines |
| US4289872A (en) | 1979-04-06 | 1981-09-15 | Allied Corporation | Macromolecular highly branched homogeneous compound based on lysine units |
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4517122A (en) | 1982-02-12 | 1985-05-14 | The Dow Chemical Company | Cyclic peptides |
| US4600535A (en) | 1982-02-12 | 1986-07-15 | The Dow Chemical Company | Cyclic peptides |
| US4558120A (en) | 1983-01-07 | 1985-12-10 | The Dow Chemical Company | Dense star polymer |
| US4507466A (en) | 1983-01-07 | 1985-03-26 | The Dow Chemical Corporation | Dense star polymers having core, core branches, terminal groups |
| US4568737A (en) | 1983-01-07 | 1986-02-04 | The Dow Chemical Company | Dense star polymers and dendrimers |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4515920A (en) | 1984-04-30 | 1985-05-07 | The Rockefeller University | Synthesis of peptides and proteins |
| JPS6147500A (ja) | 1984-08-15 | 1986-03-07 | Res Dev Corp Of Japan | キメラモノクロ−ナル抗体及びその製造法 |
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| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
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| US20020052311A1 (en) | 1999-09-03 | 2002-05-02 | Beka Solomon | Methods and compostions for the treatment and/or diagnosis of neurological diseases and disorders |
| JP2003509020A (ja) | 1999-09-03 | 2003-03-11 | ラモット・ユニバーシティ・オーソリティ・フォー・アプライド・リサーチ・アンド・インダストリアル・ディベロップメント・リミテッド | プラーク形成疾患の診断、治療、予防に有用な薬剤、組成物、その使用法 |
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| GB0720912D0 (en) * | 2007-10-25 | 2007-12-05 | Univ Cardiff | Monoclonal Anitbody for APP |
-
2003
- 2003-03-04 IL IL16381203A patent/IL163812A0/xx unknown
- 2003-03-04 EP EP10185941A patent/EP2292247A3/en not_active Withdrawn
- 2003-03-04 ES ES03744143T patent/ES2392247T3/es not_active Expired - Lifetime
- 2003-03-04 EP EP03744143A patent/EP1480666B1/en not_active Expired - Lifetime
- 2003-03-04 AU AU2003225636A patent/AU2003225636A1/en not_active Abandoned
- 2003-03-04 WO PCT/US2003/006388 patent/WO2003076455A2/en not_active Ceased
- 2003-03-04 US US10/506,665 patent/US7494655B2/en not_active Expired - Fee Related
- 2003-03-04 JP JP2003574670A patent/JP2005532276A/ja active Pending
- 2003-03-04 CA CA2477675A patent/CA2477675C/en not_active Expired - Fee Related
-
2004
- 2004-08-30 IL IL163812A patent/IL163812A/en not_active IP Right Cessation
-
2007
- 2007-04-03 US US11/695,948 patent/US7854931B2/en not_active Expired - Fee Related
-
2010
- 2010-05-18 JP JP2010114047A patent/JP2010248197A/ja active Pending
- 2010-12-06 US US12/961,248 patent/US8613928B2/en not_active Expired - Fee Related
-
2011
- 2011-05-08 IL IL212752A patent/IL212752A/en not_active IP Right Cessation
-
2013
- 2013-05-21 JP JP2013107244A patent/JP5717210B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003225636A8 (en) | 2003-09-22 |
| US20070172484A1 (en) | 2007-07-26 |
| IL212752A0 (en) | 2011-07-31 |
| WO2003076455A3 (en) | 2004-04-08 |
| EP2292247A3 (en) | 2011-10-05 |
| JP2010248197A (ja) | 2010-11-04 |
| US20110070249A1 (en) | 2011-03-24 |
| CA2477675C (en) | 2013-05-21 |
| JP2013181034A (ja) | 2013-09-12 |
| US7494655B2 (en) | 2009-02-24 |
| IL163812A (en) | 2011-06-30 |
| US8613928B2 (en) | 2013-12-24 |
| IL212752A (en) | 2014-01-30 |
| ES2392247T3 (es) | 2012-12-07 |
| EP1480666A4 (en) | 2006-06-07 |
| EP2292247A2 (en) | 2011-03-09 |
| EP1480666B1 (en) | 2012-06-13 |
| US20060034855A1 (en) | 2006-02-16 |
| CA2477675A1 (en) | 2003-09-18 |
| JP2005532276A (ja) | 2005-10-27 |
| US7854931B2 (en) | 2010-12-21 |
| JP5717210B2 (ja) | 2015-05-13 |
| EP1480666A2 (en) | 2004-12-01 |
| IL163812A0 (en) | 2005-12-18 |
| WO2003076455A2 (en) | 2003-09-18 |
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