AU2002354846B2 - Pharmaceutical composition comprising factor VII polypeptides and factor XI polypeptides - Google Patents

Pharmaceutical composition comprising factor VII polypeptides and factor XI polypeptides Download PDF

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Publication number
AU2002354846B2
AU2002354846B2 AU2002354846A AU2002354846A AU2002354846B2 AU 2002354846 B2 AU2002354846 B2 AU 2002354846B2 AU 2002354846 A AU2002354846 A AU 2002354846A AU 2002354846 A AU2002354846 A AU 2002354846A AU 2002354846 B2 AU2002354846 B2 AU 2002354846B2
Authority
AU
Australia
Prior art keywords
factor
factor vii
related polypeptide
vii
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2002354846A
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English (en)
Other versions
AU2002354846A1 (en
Inventor
Rasmus Rojkjaer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk Health Care AG
Original Assignee
Novo Nordisk Health Care AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk Health Care AG filed Critical Novo Nordisk Health Care AG
Publication of AU2002354846A1 publication Critical patent/AU2002354846A1/en
Application granted granted Critical
Publication of AU2002354846B2 publication Critical patent/AU2002354846B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4846Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU2002354846A 2001-07-20 2002-07-19 Pharmaceutical composition comprising factor VII polypeptides and factor XI polypeptides Ceased AU2002354846B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200101127 2001-07-20
DKPA200101127 2001-07-20
PCT/DK2002/000505 WO2003007983A1 (en) 2001-07-20 2002-07-19 Pharmaceutical composition comprising factor vii polypeptides and factor xi polypeptides

Publications (2)

Publication Number Publication Date
AU2002354846A1 AU2002354846A1 (en) 2003-05-22
AU2002354846B2 true AU2002354846B2 (en) 2007-08-02

Family

ID=8160632

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002354846A Ceased AU2002354846B2 (en) 2001-07-20 2002-07-19 Pharmaceutical composition comprising factor VII polypeptides and factor XI polypeptides

Country Status (16)

Country Link
EP (1) EP1411973A1 (pt)
JP (1) JP2004534855A (pt)
KR (1) KR20040015821A (pt)
CN (1) CN1304050C (pt)
AU (1) AU2002354846B2 (pt)
BR (1) BR0211256A (pt)
CA (1) CA2452677A1 (pt)
CZ (1) CZ200439A3 (pt)
HU (1) HUP0400976A3 (pt)
IL (1) IL159622A0 (pt)
MX (1) MXPA04000415A (pt)
NO (1) NO20040235L (pt)
PL (1) PL369077A1 (pt)
RU (1) RU2298416C2 (pt)
WO (1) WO2003007983A1 (pt)
ZA (1) ZA200400012B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100411684C (zh) 1999-07-14 2008-08-20 诺沃挪第克健康护理股份公司 FVIIa或组织因子拮抗剂在调节基因表达和细胞迁移或趋化中的应用
ES2381110T3 (es) 2003-09-09 2012-05-23 Novo Nordisk Health Care Ag Polipéptidos de factor VII de coagulación
BRPI0416461A (pt) * 2003-11-20 2007-03-06 Novo Nordisk Healthcare Ag método para o tratamento de episódios de sangramento, formulação farmacêutica, e, uso de um polipeptìdeo fxi
WO2005074974A1 (en) * 2004-02-05 2005-08-18 Novo Nordisk Health Care Ag Use of factor viia for treating late complications of trauma
WO2006128497A1 (en) * 2005-06-01 2006-12-07 Novo Nordisk A/S Pharmaceutical formulation of factor xi
JP5739816B2 (ja) 2008-12-19 2015-06-24 バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated Tfpiインヒビターおよび使用法
NZ603028A (en) 2010-03-19 2014-11-28 Baxter Healthcare Sa Tfpi inhibitors and methods of use
AU2011313505B2 (en) * 2010-10-06 2015-09-17 Medimmune Limited Factor II and fibrinogen for treatment of haemostatic disorders
KR102263685B1 (ko) 2012-03-21 2021-06-11 다케다 야쿠힌 고교 가부시키가이샤 Tfpi 저해제 및 사용 방법
EP3099171A4 (en) * 2014-01-31 2017-08-09 Dana-Farber Cancer Institute, Inc. Dihydropteridinone derivatives and uses thereof
WO2016201370A1 (en) 2015-06-12 2016-12-15 Dana-Farber Cancer Institute, Inc. Combination therapy of transcription inhibitors and kinase inhibitors
CR20180336A (es) 2015-11-25 2018-08-06 Dana Farber Cancer Inst Inc Inhibidores de bromodominio bivalentes y usos de los mismos
US11958911B2 (en) 2017-02-10 2024-04-16 Shanghai Benemae Pharmaceutical Anti-coagulation factor XI antibody

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0225160A2 (en) * 1985-11-26 1987-06-10 Novo Nordisk A/S Compositions and methods for the treatment of bleeding disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59116213A (ja) * 1982-12-24 1984-07-05 Unitika Ltd エアゾ−ル組成物
US5580560A (en) * 1989-11-13 1996-12-03 Novo Nordisk A/S Modified factor VII/VIIa
FR2676231A1 (fr) * 1991-05-07 1992-11-13 Aetsrn Concentre de facteur xi de la coagulation sanguine a haute activite specifique, approprie a usage therapeutique et son procede de preparation.
EP2253703A1 (en) * 2000-09-13 2010-11-24 Novo Nordisk Health Care AG Human coagulation factor VII variants

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0225160A2 (en) * 1985-11-26 1987-06-10 Novo Nordisk A/S Compositions and methods for the treatment of bleeding disorders

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Bajaj et al (1983) Biochemistry, vol 22, pp 4047-4053 *
Zur et al (1980) J of Biol Chem, vol 255(12), pp 5703-5707 *

Also Published As

Publication number Publication date
CA2452677A1 (en) 2003-01-30
KR20040015821A (ko) 2004-02-19
PL369077A1 (en) 2005-04-18
HUP0400976A2 (hu) 2004-08-30
NO20040235L (no) 2004-03-17
WO2003007983A1 (en) 2003-01-30
CN1304050C (zh) 2007-03-14
MXPA04000415A (es) 2004-11-22
RU2298416C2 (ru) 2007-05-10
CN1556710A (zh) 2004-12-22
RU2004105031A (ru) 2005-04-20
ZA200400012B (en) 2004-08-17
JP2004534855A (ja) 2004-11-18
EP1411973A1 (en) 2004-04-28
HUP0400976A3 (en) 2006-01-30
IL159622A0 (en) 2004-06-01
CZ200439A3 (cs) 2005-03-16
BR0211256A (pt) 2004-07-27

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired