AU2002334799B2 - Cripto-specific antibodies - Google Patents

Cripto-specific antibodies Download PDF

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Publication number
AU2002334799B2
AU2002334799B2 AU2002334799A AU2002334799A AU2002334799B2 AU 2002334799 B2 AU2002334799 B2 AU 2002334799B2 AU 2002334799 A AU2002334799 A AU 2002334799A AU 2002334799 A AU2002334799 A AU 2002334799A AU 2002334799 B2 AU2002334799 B2 AU 2002334799B2
Authority
AU
Australia
Prior art keywords
antibody
cripto
antibodies
tumor
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2002334799A
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English (en)
Other versions
AU2002334799A1 (en
Inventor
Heather Adkins
Steven Donald Miklasz
Paul Rayhorn
Michele Sanicola-Nadel
Susan Gail Schiffer
Kevin P. Williams
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biogen MA Inc
Original Assignee
Biogen MA Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2002/011950 external-priority patent/WO2002088170A2/en
Application filed by Biogen MA Inc filed Critical Biogen MA Inc
Publication of AU2002334799A1 publication Critical patent/AU2002334799A1/en
Assigned to BIOGEN IDEC MA INC. reassignment BIOGEN IDEC MA INC. Amend patent request/document other than specification (104) Assignors: BIOGEN, INC.
Application granted granted Critical
Publication of AU2002334799B2 publication Critical patent/AU2002334799B2/en
Assigned to BIOGEN MA INC. reassignment BIOGEN MA INC. Request to Amend Deed and Register Assignors: BIOGEN IDEC MA INC.
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2002334799A 2001-04-26 2002-10-01 Cripto-specific antibodies Ceased AU2002334799B2 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US60/286,782 2001-04-26
US60/293,020 2001-05-17
US60/301,091 2001-06-26
US36700202P 2002-03-22 2002-03-22
US60/367,002 2002-03-22
AUPCT/US2002/011950 2002-04-17
PCT/US2002/011950 WO2002088170A2 (en) 2001-04-26 2002-04-17 Cripto blocking antibodies and uses thereof
PCT/US2002/031462 WO2003083041A2 (en) 2002-03-22 2002-10-01 Cripto-specific antibodies

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
AU2002303364A Division AU2002303364A1 (en) 2001-04-26 2002-04-17 Cripto blocking antibodies and uses thereof

Publications (2)

Publication Number Publication Date
AU2002334799A1 AU2002334799A1 (en) 2003-10-13
AU2002334799B2 true AU2002334799B2 (en) 2009-05-07

Family

ID=29586137

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002334799A Ceased AU2002334799B2 (en) 2001-04-26 2002-10-01 Cripto-specific antibodies

Country Status (4)

Country Link
EP (1) EP1494693B1 (https=)
JP (1) JP2005520566A (https=)
AU (1) AU2002334799B2 (https=)
WO (1) WO2003083041A2 (https=)

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US20100111856A1 (en) 2004-09-23 2010-05-06 Herman Gill Zirconium-radiolabeled, cysteine engineered antibody conjugates
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US20100041032A1 (en) * 2006-04-28 2010-02-18 Biogen Idec Ma Inc. Composition and methods for the detection of cripto-3
WO2008150530A2 (en) * 2007-06-01 2008-12-11 Biogen Idec Ma Inc. Cripto binding molecules
WO2009011572A1 (en) 2007-07-13 2009-01-22 Bac Ip B.V. Single-domain antigen-binding proteins that bind mammalian igg
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GB0020953D0 (en) * 2000-08-24 2000-10-11 Smithkline Beecham Biolog Vaccine
PL207087B1 (pl) * 2001-04-26 2010-10-29 Biogen Przeciwciało, które wiąże się swoiście z białkiem Cripto, zawierająca je kompozycja farmaceutyczna i zastosowanie przeciwciała

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Also Published As

Publication number Publication date
EP1494693A4 (en) 2006-08-02
WO2003083041A2 (en) 2003-10-09
WO2003083041A3 (en) 2003-12-04
AU2002334799A1 (en) 2003-10-13
EP1494693A2 (en) 2005-01-12
JP2005520566A (ja) 2005-07-14
EP1494693B1 (en) 2010-12-08
WO2003083041A8 (en) 2004-09-16

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